ES518582A0 - Un procedimiento para preparar una composicion farmaceutica acuosa que contiene ubidecarenona. - Google Patents
Un procedimiento para preparar una composicion farmaceutica acuosa que contiene ubidecarenona.Info
- Publication number
- ES518582A0 ES518582A0 ES518582A ES518582A ES518582A0 ES 518582 A0 ES518582 A0 ES 518582A0 ES 518582 A ES518582 A ES 518582A ES 518582 A ES518582 A ES 518582A ES 518582 A0 ES518582 A0 ES 518582A0
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- procedure
- pharmaceutical composition
- composition containing
- aqueous pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 2
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 2
- 235000017471 coenzyme Q10 Nutrition 0.000 title abstract 2
- 229960004747 ubidecarenone Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56209972A JPS58113127A (ja) | 1981-12-28 | 1981-12-28 | ユビデカレノン含有水性液 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8402503A1 ES8402503A1 (es) | 1984-02-01 |
| ES518582A0 true ES518582A0 (es) | 1984-02-01 |
Family
ID=16581723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES518582A Granted ES518582A0 (es) | 1981-12-28 | 1982-12-27 | Un procedimiento para preparar una composicion farmaceutica acuosa que contiene ubidecarenona. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4483873A (es) |
| EP (1) | EP0083108B1 (es) |
| JP (1) | JPS58113127A (es) |
| KR (1) | KR880002410B1 (es) |
| AT (1) | ATE22006T1 (es) |
| CA (1) | CA1176568A (es) |
| DE (1) | DE3273257D1 (es) |
| ES (1) | ES518582A0 (es) |
| NO (1) | NO156553C (es) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1157269B (it) * | 1982-03-19 | 1987-02-11 | Seuref Ag | Nuove formulazioni farmaceutiche contenenti il coenzima q10 adatte per la somministrazione topica |
| JPS5910511A (ja) * | 1982-07-07 | 1984-01-20 | Eisai Co Ltd | 脂溶性物質含有水性液 |
| JPS6025918A (ja) * | 1983-07-25 | 1985-02-08 | Ajinomoto Co Inc | 脂溶性薬物含有水性液 |
| CH661438A5 (it) * | 1984-04-09 | 1987-07-31 | Seuref Ag | Composizioni farmaceutiche ad azione antianossica e metabolica cerebrale. |
| IT1191608B (it) * | 1985-02-01 | 1988-03-23 | Zambon Spa | Composizione farmaceutica e forme farmaceutiche che la contengono |
| US4824669A (en) * | 1985-04-11 | 1989-04-25 | Board Of Regents, The University Of Texas System | Formulations of coenzyme Q10 for intravenous use |
| DE3524788A1 (de) * | 1985-07-11 | 1987-01-22 | Lentia Gmbh | Stabile, intravenoes applizierbare, waessrige fettemulsion und ein verfahren zu deren herstellung |
| CH667387A5 (it) * | 1985-12-24 | 1988-10-14 | Seuref Ag | Formulazioni farmaceutiche acquose di ubichinone. |
| US4911929A (en) * | 1986-08-29 | 1990-03-27 | The United States Of America As Represented By The Secretary Of The Navy | Blood substitute comprising liposome-encapsulated hemoglobin |
| US5154930A (en) * | 1987-03-05 | 1992-10-13 | The Liposome Company, Inc. | Pharmacological agent-lipid solution preparation |
| CA1323306C (en) * | 1987-03-05 | 1993-10-19 | Mircea C. Popescu | Pharmacological agent-lipid solution preparation |
| IT1250672B (it) * | 1991-07-11 | 1995-04-21 | Idb Holding Spa | Formulazioni orali di ubidecarenone in soluzione acquosa |
| ES2051643B1 (es) * | 1992-10-13 | 1995-02-16 | Inverni Della Beffa Farma | Formulaciones orales de ubidecarenona en forma de soluciones acuosas. |
| GR1001364B (el) * | 1992-10-16 | 1993-10-29 | Inverni Della Beffa Farma | Από του στόματος συν?έσεις ουβιδεκαρενόνης υπό μορφήν υδατικών διαλυμάτων. |
| JP3106820B2 (ja) * | 1993-12-08 | 2000-11-06 | アールティーエー・アソシエーツ有限会社 | 畜肉、魚肉およびこれらの加工品の鮮度保持剤並びに生産性改善剤 |
| DE4405545A1 (de) * | 1994-02-22 | 1995-08-31 | Dietl Hans | Fettlösliche Vitamine enthaltende Zubereitung zur oralen Applikation |
| US6403116B1 (en) | 2000-11-03 | 2002-06-11 | Triarco Inductries, Inc. | Coenzyme Q10 formulation |
| US6300377B1 (en) * | 2001-02-22 | 2001-10-09 | Raj K. Chopra | Coenzyme Q products exhibiting high dissolution qualities |
| US20050260752A1 (en) * | 2003-04-01 | 2005-11-24 | Wilding Martin G | Culture medium containing enhancers of oxidative phosphorylation |
| US7438903B2 (en) * | 2003-06-06 | 2008-10-21 | Nbty, Inc. | Methods and compositions that enhance bioavailability of coenzyme-Q10 |
| EP2371363B1 (en) | 2004-01-22 | 2020-04-08 | University of Miami | Coenzyme Q10 formulations for use in the treatment of solid tumours |
| US7803366B2 (en) * | 2004-05-07 | 2010-09-28 | Nbty, Inc. | Methods and compositions that enhance bioavailability of coenzyme-Q10 |
| KR20100136997A (ko) | 2008-04-11 | 2010-12-29 | 싸이토테크 랩스, 엘엘씨 | 암세포에서 아폽토시스를 유도하는 방법 및 용도 |
| JPWO2010021034A1 (ja) * | 2008-08-20 | 2012-01-26 | 昭和電工株式会社 | 皮膚外用剤 |
| WO2010111397A1 (en) * | 2009-03-24 | 2010-09-30 | Adds Pharmaceuticals Llc | Stabilized solubility-enhanced formulations for oral delivery |
| SG10201402287TA (en) | 2009-05-11 | 2014-07-30 | Berg Llc | Methods for the diagnosis of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
| WO2012138765A1 (en) | 2011-04-04 | 2012-10-11 | Berg Pharma Llc | Methods of treating central nervous system tumors |
| MX380565B (es) | 2013-04-08 | 2025-03-12 | Berg Llc | Terapias combinadas de coenzima q10 para el tratamiento de cáncer. |
| AU2014315186B2 (en) | 2013-09-04 | 2020-02-27 | Berg Llc | Methods of treatment of cancer by continuous infusion of coenzyme Q10 |
| US20170189350A1 (en) | 2015-11-16 | 2017-07-06 | Berg Llc | Methods of treatment of temozolomide-resistant glioma using coenzyme q10 |
| PL3476388T3 (pl) | 2017-10-24 | 2022-01-24 | Difass International S.P.A. | Kompozycja zawierająca koenzym q10 i piperynę |
| EP4101442B1 (en) * | 2021-06-11 | 2025-09-03 | Tradichem Industrial Services, S.L. | Process for preparing compacted coenzyme q10 particles of high density and improved flowability |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5845403B2 (ja) * | 1976-02-14 | 1983-10-08 | エーザイ株式会社 | 補酵素ｑを主成分とする膵機能亢進剤 |
| JPS5356315A (en) * | 1976-11-01 | 1978-05-22 | Eisai Co Ltd | Emulsified solution of fat soluble drugs |
| JPS5562010A (en) * | 1978-10-31 | 1980-05-10 | Ajinomoto Co Inc | Fat emulsion for intravenous injection |
| JPS5618914A (en) * | 1979-07-25 | 1981-02-23 | Eisai Co Ltd | Ubidecarenone composition having good absorbability |
| FR2471384A1 (fr) * | 1979-12-11 | 1981-06-19 | Richter Gedeon Vegyeszet | Procede de preparation de tartrate d'ergotamine |
| FR2472384A1 (fr) * | 1979-12-27 | 1981-07-03 | Sederma Sa | Utilisation en cosmetologie de complexes naturels constitues d'ubiquinones et de phospholipides |
-
1981
- 1981-12-28 JP JP56209972A patent/JPS58113127A/ja active Granted
-
1982
- 1982-12-23 CA CA000418509A patent/CA1176568A/en not_active Expired
- 1982-12-23 US US06/452,844 patent/US4483873A/en not_active Expired - Fee Related
- 1982-12-27 ES ES518582A patent/ES518582A0/es active Granted
- 1982-12-27 NO NO824380A patent/NO156553C/no unknown
- 1982-12-28 DE DE8282112068T patent/DE3273257D1/de not_active Expired
- 1982-12-28 AT AT82112068T patent/ATE22006T1/de not_active IP Right Cessation
- 1982-12-28 KR KR8205848A patent/KR880002410B1/ko not_active Expired
- 1982-12-28 EP EP82112068A patent/EP0083108B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES8402503A1 (es) | 1984-02-01 |
| EP0083108B1 (en) | 1986-09-10 |
| NO156553C (no) | 1987-10-14 |
| NO156553B (no) | 1987-07-06 |
| ATE22006T1 (de) | 1986-09-15 |
| US4483873A (en) | 1984-11-20 |
| CA1176568A (en) | 1984-10-23 |
| JPS58113127A (ja) | 1983-07-05 |
| KR840002650A (ko) | 1984-07-16 |
| EP0083108A3 (en) | 1983-12-14 |
| NO824380L (no) | 1983-06-29 |
| JPH0322363B2 (es) | 1991-03-26 |
| KR880002410B1 (ko) | 1988-11-08 |
| DE3273257D1 (en) | 1986-10-16 |
| EP0083108A2 (en) | 1983-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20010402 |