ES481238A1 - Procedimiento para la obtencion de amino-alcoholes n-alqui- lados. - Google Patents
Procedimiento para la obtencion de amino-alcoholes n-alqui- lados.Info
- Publication number
- ES481238A1 ES481238A1 ES481238A ES481238A ES481238A1 ES 481238 A1 ES481238 A1 ES 481238A1 ES 481238 A ES481238 A ES 481238A ES 481238 A ES481238 A ES 481238A ES 481238 A1 ES481238 A1 ES 481238A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- carbon atoms
- formula
- treatment
- depression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001414 amino alcohols Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000001629 suppression Effects 0.000 abstract 2
- 206010002942 Apathy Diseases 0.000 abstract 1
- 206010012390 Depression postoperative Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 201000009916 Postpartum depression Diseases 0.000 abstract 1
- 102000004305 alpha Adrenergic Receptors Human genes 0.000 abstract 1
- 108090000861 alpha Adrenergic Receptors Proteins 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 abstract 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 230000000297 inotrophic effect Effects 0.000 abstract 1
- 229940053544 other antidepressants in atc Drugs 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 229960000581 salicylamide Drugs 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 230000002889 sympathetic effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
Procedimiento para la obtención de aminoalcoholes N-alquilados de fórmula **(Fórmula)** donde Ar significa un resto insustituido, o sustituido por hidroxi, de carácter aromático, n tiene los valores ceros ó 1 y Alk significa un resto alquileno con 2 hasta 5 átomos de carbono, donde el átomo de nitrógeno y el átomo de oxígeno, o en caso de que n esté por cero, el resto fenilo están separados entre sí como mínimo por dos átomos de carbono, y sus sales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH613678 | 1978-06-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES481238A1 true ES481238A1 (es) | 1980-02-16 |
Family
ID=4304840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES481238A Expired ES481238A1 (es) | 1978-06-05 | 1979-06-04 | Procedimiento para la obtencion de amino-alcoholes n-alqui- lados. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4460580A (es) |
| EP (1) | EP0005848B1 (es) |
| JP (1) | JPS54163543A (es) |
| KR (4) | KR840000926B1 (es) |
| AR (3) | AR229581A1 (es) |
| AT (1) | ATE511T1 (es) |
| AU (1) | AU522483B2 (es) |
| CA (1) | CA1124241A (es) |
| CY (1) | CY1256A (es) |
| DD (1) | DD144050A5 (es) |
| DE (1) | DE2961669D1 (es) |
| DK (1) | DK229879A (es) |
| ES (1) | ES481238A1 (es) |
| FI (1) | FI791727A7 (es) |
| GB (1) | GB2026474B (es) |
| GR (1) | GR74057B (es) |
| HK (1) | HK15585A (es) |
| HU (1) | HU182019B (es) |
| IL (1) | IL57471A (es) |
| MY (1) | MY8500690A (es) |
| NO (1) | NO149034C (es) |
| NZ (1) | NZ190632A (es) |
| PL (5) | PL116612B1 (es) |
| PT (1) | PT69723A (es) |
| SG (1) | SG45884G (es) |
| ZA (1) | ZA792748B (es) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2965655D1 (en) * | 1978-06-28 | 1983-07-21 | Beecham Group Plc | Secondary amines, their preparation, pharmaceutical compositions containing them and their use |
| ZA803879B (en) | 1979-06-29 | 1981-06-24 | Glaxo Group Ltd | Heterocyclic compounds, processes for their preparation and their use |
| DD157796A5 (de) * | 1979-12-04 | 1982-12-08 | Ciba Geigy Ag | Verfahren zur herstellung neuer derivate des 2-amino-aethanols |
| JPS5726653A (en) * | 1980-05-09 | 1982-02-12 | Ciba Geigy Ag | Substituted phenyl ether |
| DE3026534A1 (de) * | 1980-07-12 | 1982-03-18 | C.H. Boehringer Sohn, 6507 Ingelheim | 3,1-benzoxazin-2-one, ihre herstellung und verwendung |
| GR74992B (es) * | 1980-08-13 | 1984-07-12 | Ciba Geigy Ag | |
| JPS57185243A (en) * | 1981-05-08 | 1982-11-15 | Ciba Geigy Ag | Substituted 2-aminoethanol |
| US4466965A (en) * | 1982-07-26 | 1984-08-21 | American Hospital Supply Corporation | Phthalazine compounds, compositions and use |
| FR2543139B1 (fr) * | 1983-03-22 | 1985-08-16 | Cerm Cent Europ Rech Mauvernay | Derives de (1-alcoxy 2-amino) ethyl pyridine ou pyrazine, leur preparation et leur application en therapeutique |
| DE3621775A1 (de) * | 1986-03-13 | 1988-01-07 | Thomae Gmbh Dr K | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE3608290A1 (de) * | 1986-03-13 | 1987-09-24 | Thomae Gmbh Dr K | Neue substituierte thiazole und oxazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| CA1287061C (en) * | 1986-06-27 | 1991-07-30 | Roche Holding Ltd. | Pyridine ethanolamine derivatives |
| GB8714901D0 (en) * | 1986-07-23 | 1987-07-29 | Ici Plc | Amide derivatives |
| DE3627663A1 (de) * | 1986-08-14 | 1988-03-03 | Bayer Ag | Heteroarylethylamine, verfahren zu ihrer herstellung und ihre verwendung als leistungsfoerderer bei tieren |
| US5108363A (en) * | 1988-02-19 | 1992-04-28 | Gensia Pharmaceuticals, Inc. | Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist |
| GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
| JPH0466934A (ja) * | 1990-07-04 | 1992-03-03 | Fuji Photo Film Co Ltd | ハロゲン化銀写真感光材料 |
| US5232948A (en) * | 1990-09-10 | 1993-08-03 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted monocyclic aryl compounds exhibiting selective leukotriene b4 antagonist activity |
| US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
| US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
| US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| ES2256370T3 (es) * | 1991-08-23 | 2006-07-16 | Nps Pharmaceuticals, Inc. | Moleculas activas para el receptor de calcio. |
| US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
| US5208252A (en) * | 1992-07-24 | 1993-05-04 | Ortho Pharmaceutical Corporation | Aminoethylthiophene derivatives |
| US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| WO1995019336A1 (de) * | 1994-01-12 | 1995-07-20 | Iovis Biomedical And Pharmaceutical Consultants | Phenylethanolaminether und ihre verwendung als beta-adrenorezeptor-agonisten |
| HU229474B1 (en) | 1994-10-21 | 2014-01-28 | Nps Pharma Inc | Calcium receptor-active compounds, pharmaceutical compositions containing them and use of the compositions |
| ES2201300T3 (es) * | 1996-05-01 | 2004-03-16 | Nps Pharmaceuticals, Inc. | Compuestos activos frente a receptores de iones inorganicos. |
| KR100380520B1 (ko) * | 2000-09-08 | 2003-04-23 | 한국화학연구원 | 피리딘을 포함한 β-아미노알코올 유도체 |
| US20050151459A1 (en) * | 2002-04-22 | 2005-07-14 | Geerdinck Leonie M. | Luminescent screen |
| US7538141B2 (en) * | 2004-03-23 | 2009-05-26 | Alan Daniel Brown | Compounds for the treatment of diseases |
| WO2011112243A2 (en) * | 2010-03-08 | 2011-09-15 | The University Of Tennessee Research Foundation | Beta -adrenergic receptor agonists and uses thereof |
| ITMI20122221A1 (it) * | 2012-12-21 | 2014-06-22 | C4T S C A R L | Nuovi composti del 2,3-diidro-4h-1,3-benzossazin-4-one, metodo per prepararli e forma farmaceutica che li comprende |
| CN104008939B (zh) * | 2014-06-19 | 2016-05-11 | 苏州普京真空技术有限公司 | 一种耐用电子枪灯丝 |
| USD954933S1 (en) | 2018-06-01 | 2022-06-14 | Chiaro Technology Limited | Breast pump accessory |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1178400A (en) * | 1966-12-13 | 1970-01-21 | Delalande Sa | Nitrogen Substituted Amines and their process of Preparation. |
| DE1543538A1 (de) * | 1966-12-30 | 1976-02-05 | Degussa | Verfahren zur herstellung neuer heterocyclischer aminoalkohole |
| US4012444A (en) * | 1969-07-08 | 1977-03-15 | Allen & Hanburys Limited | 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof |
| GB1301134A (en) * | 1970-07-18 | 1972-12-29 | Pfizer Ltd | SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES |
| GB1398738A (en) * | 1972-12-05 | 1975-06-25 | Pfizer Ltd | Propanolamine derivatives |
| US4082772A (en) * | 1975-04-18 | 1978-04-04 | American Home Products Corporation | Thiophene ethanolamines |
| US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
-
1979
- 1979-05-30 DD DD79213267A patent/DD144050A5/de unknown
- 1979-05-30 FI FI791727A patent/FI791727A7/fi not_active Application Discontinuation
- 1979-06-01 CA CA328,929A patent/CA1124241A/en not_active Expired
- 1979-06-01 AT AT79101724T patent/ATE511T1/de active
- 1979-06-01 NO NO791841A patent/NO149034C/no unknown
- 1979-06-01 EP EP79101724A patent/EP0005848B1/de not_active Expired
- 1979-06-01 DE DE7979101724T patent/DE2961669D1/de not_active Expired
- 1979-06-01 DK DK229879A patent/DK229879A/da not_active Application Discontinuation
- 1979-06-01 CY CY1256A patent/CY1256A/xx unknown
- 1979-06-01 NZ NZ190632A patent/NZ190632A/en unknown
- 1979-06-04 ES ES481238A patent/ES481238A1/es not_active Expired
- 1979-06-04 PL PL1979222399A patent/PL116612B1/pl unknown
- 1979-06-04 PL PL1979222398A patent/PL117158B1/pl unknown
- 1979-06-04 PL PL1979216090A patent/PL116529B1/pl unknown
- 1979-06-04 AU AU47736/79A patent/AU522483B2/en not_active Ceased
- 1979-06-04 ZA ZA792748A patent/ZA792748B/xx unknown
- 1979-06-04 PL PL1979222397A patent/PL117155B1/pl unknown
- 1979-06-04 GB GB7919470A patent/GB2026474B/en not_active Expired
- 1979-06-04 HU HU79CI1940A patent/HU182019B/hu unknown
- 1979-06-04 PT PT69723A patent/PT69723A/pt unknown
- 1979-06-04 KR KR7901814A patent/KR840000926B1/ko not_active Expired
- 1979-06-04 PL PL1979222400A patent/PL116597B1/pl unknown
- 1979-06-04 IL IL57471A patent/IL57471A/xx unknown
- 1979-06-05 GR GR59274A patent/GR74057B/el unknown
- 1979-06-05 JP JP6952479A patent/JPS54163543A/ja active Pending
-
1980
- 1980-12-17 AR AR283670A patent/AR229581A1/es active
- 1980-12-17 AR AR283669A patent/AR229951A1/es active
- 1980-12-17 AR AR283668A patent/AR229022A1/es active
-
1982
- 1982-03-12 KR KR1019820001067A patent/KR830000680A/ko not_active Ceased
- 1982-03-12 KR KR1019820001068A patent/KR830000681A/ko not_active Ceased
- 1982-03-12 KR KR1019820001066A patent/KR830000679A/ko not_active Ceased
- 1982-06-24 US US06/391,814 patent/US4460580A/en not_active Expired - Fee Related
-
1984
- 1984-06-23 SG SG458/84A patent/SG45884G/en unknown
-
1985
- 1985-03-07 HK HK155/85A patent/HK15585A/xx unknown
- 1985-12-30 MY MY690/85A patent/MY8500690A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |