[go: up one dir, main page]

ES480602A1 - Un procedimiento para la preparacion de nuevos derivados de indol. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de indol.

Info

Publication number
ES480602A1
ES480602A1 ES480602A ES480602A ES480602A1 ES 480602 A1 ES480602 A1 ES 480602A1 ES 480602 A ES480602 A ES 480602A ES 480602 A ES480602 A ES 480602A ES 480602 A1 ES480602 A1 ES 480602A1
Authority
ES
Spain
Prior art keywords
formula
preparation
pharmaceutical compositions
indole derivatives
indicated above
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480602A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Publication of ES480602A1 publication Critical patent/ES480602A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Un procedimiento para la preparación de nuevos derivados de indel, de la fórmula general II **(Fórmula-01)** o una sal de adición de ácido o amónico cuaternaria respectiva, en donde R5 representa hidrógeno, hidroxilo, alcoxilo inferior o alquilo inferior, R6 representa hidrógeno o alquilo inferior, y R7 representa fenilo, alcoxi-fenilo inferior, halofenilo, o tenilo y X representa oxígeno o azufre, caracterizado porque se acila un derivado de indol de la fórmula V **(Fórmula-02)** en donde R5, R6 y X tienen el significado antes indicado, con un agente acilante que contiene el grupo COR7 en donde R7 tiene el significado antes indicado y, si se desea, se aisla el producto de la fórmula II como una sal de adición de ácido o amónica cuaternaria.
ES480602A 1977-12-01 1979-05-16 Un procedimiento para la preparacion de nuevos derivados de indol. Expired ES480602A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB50053/77A GB1586817A (en) 1977-12-01 1977-12-01 Indole derivatives

Publications (1)

Publication Number Publication Date
ES480602A1 true ES480602A1 (es) 1980-04-01

Family

ID=10454471

Family Applications (4)

Application Number Title Priority Date Filing Date
ES475565A Expired ES475565A1 (es) 1977-12-01 1978-11-30 Un procedimiento para la preparacion de nuevos derivados de indol
ES480602A Expired ES480602A1 (es) 1977-12-01 1979-05-16 Un procedimiento para la preparacion de nuevos derivados de indol.
ES480603A Expired ES480603A1 (es) 1977-12-01 1979-05-16 Un procedimiento para la preparacion de nuevos derivados de indol.
ES480604A Expired ES480604A1 (es) 1977-12-01 1979-05-16 Un procedimiento para la preparacion de nuevos derivados de indol.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES475565A Expired ES475565A1 (es) 1977-12-01 1978-11-30 Un procedimiento para la preparacion de nuevos derivados de indol

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES480603A Expired ES480603A1 (es) 1977-12-01 1979-05-16 Un procedimiento para la preparacion de nuevos derivados de indol.
ES480604A Expired ES480604A1 (es) 1977-12-01 1979-05-16 Un procedimiento para la preparacion de nuevos derivados de indol.

Country Status (20)

Country Link
US (1) US4209521A (es)
EP (1) EP0002886B1 (es)
JP (1) JPS5585586A (es)
AT (1) AT365591B (es)
AU (1) AU516185B2 (es)
CA (1) CA1093558A (es)
DE (1) DE2861179D1 (es)
DK (1) DK513678A (es)
ES (4) ES475565A1 (es)
FI (1) FI783473A7 (es)
GB (1) GB1586817A (es)
HU (1) HU179361B (es)
IE (1) IE47461B1 (es)
IT (1) IT1100596B (es)
NZ (1) NZ188773A (es)
PH (1) PH19933A (es)
PT (1) PT68850A (es)
SU (4) SU1042612A3 (es)
YU (1) YU280378A (es)
ZA (1) ZA786058B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4722930A (en) * 1980-03-01 1988-02-02 John Wyeth And Brother Limited 3-benzoyl-1-[(oxo or thioheteroaryl-ylalkyl)-piperid-4-yl]ureas and derivatives
US4806552A (en) * 1980-03-01 1989-02-21 John Wyeth & Brother, Limited Pyridyl- and/or pyridoyl-(piperid-4-yl) ureas and analogues thereof
IL62200A (en) * 1980-03-01 1984-09-30 Wyeth John & Brother Ltd Piperidine derivatives,their preparation and pharmaceutical compositions containing them
US4808601A (en) * 1984-09-19 1989-02-28 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US4752609A (en) * 1985-06-20 1988-06-21 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
GB8528234D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
WO2004105753A1 (ja) * 2003-05-29 2004-12-09 Kyowa Medex Co., Ltd. 抗うつ剤または抗うつ用飲食品
AR070398A1 (es) * 2008-02-22 2010-03-31 Gruenenthal Chemie Derivados sustituidos de indol
SG11202003739SA (en) * 2017-11-03 2020-05-28 Bioimics Ab Anti-infective heterocyclic compounds and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1425354A (en) * 1973-10-10 1976-02-18 Wyeth John & Brother Ltd Indole derivatives
GB1494805A (en) * 1975-07-17 1977-12-14 Wyeth John & Brother Ltd Indole derivatives
US4061641A (en) * 1973-10-10 1977-12-06 John Wyeth & Brother Limited Ureidopiperidino-ketoalkyl indoles
ZA76475B (en) * 1975-03-10 1977-08-31 Ciba Geigy Ag Indolyalkylpiperidines

Also Published As

Publication number Publication date
IE47461B1 (en) 1984-03-21
JPS6257606B2 (es) 1987-12-02
SU1083910A3 (ru) 1984-03-30
EP0002886A2 (en) 1979-07-11
PH19933A (en) 1986-08-14
AU516185B2 (en) 1981-05-21
ATA853578A (de) 1981-06-15
NZ188773A (en) 1981-03-16
GB1586817A (en) 1981-03-25
SU1087073A3 (ru) 1984-04-15
DE2861179D1 (en) 1981-12-24
EP0002886B1 (en) 1981-10-14
SU1110380A3 (ru) 1984-08-23
HU179361B (en) 1982-10-28
YU280378A (en) 1983-01-21
SU1042612A3 (ru) 1983-09-15
US4209521A (en) 1980-06-24
IT7830109A0 (it) 1978-11-23
IT1100596B (it) 1985-09-28
ES475565A1 (es) 1980-01-16
CA1093558A (en) 1981-01-13
ZA786058B (en) 1980-05-28
IE782100L (en) 1979-06-01
JPS5585586A (en) 1980-06-27
ES480604A1 (es) 1980-04-01
ES480603A1 (es) 1980-04-01
FI783473A7 (fi) 1979-06-02
AT365591B (de) 1982-01-25
EP0002886A3 (en) 1979-07-25
AU4123178A (en) 1979-06-07
DK513678A (da) 1979-06-02
PT68850A (en) 1978-12-01

Similar Documents

Publication Publication Date Title
AR223455A1 (es) Composiciones fungicidas que contienen derivados de n-(3-(p-ter.butil-fenil)o 3-(p-ter.butilciclohexil)-2-metilpropil o-2-metilprop-2-enil)-morfolina o piperidina y sus n-oxidos,estos compuestos para su exclusivo uso en dichas composiciones y procedimiento para su preparacion
HK12184A (en) Substituted ortho-anisamides, methods of preparing them, compositions containing them and their application as psychotropic agents
ES8406429A1 (es) "un metodo de preparacion de nuevas sulfonamidas sustituidas" nota: se solicita como divisional de la patente de invencion n 516.504.
BR8000046A (pt) Composicao, dispersao de um solido silicoso em um meio organico formado de uma composicao, dispersao de silica em um meio organico, composicao dental, e recipiente pequeno
ATE46157T1 (de) Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel.
FR2285854A1 (fr) Derives du phenyl-2 benzofuranne et compositions cosmetiques les contenant
ES435246A1 (es) Procedimiento para preparar derivados de piperidina.
ES480602A1 (es) Un procedimiento para la preparacion de nuevos derivados de indol.
SE7611137L (sv) 1-bensazolylalkyl-4-substituerade piperidiner
FI810559L (fi) Nya 3,4,5-trihydroxipiperidinderivat foerfaranden foer deras framstaellning och deras anvaendning som laekemedel samt i djurnaering
CO4980887A1 (es) Nueva 3,4-diariltiazolina-2-uno o 2-tiono derivados, sus metodos de preparacion y su uso terapeutico
FI803264L (fi) 2-hydroxialkyl-3,4,5-trihydroxipiperidiner foerfarande foer framstaellning av dem och anvaendning av dem som laekemedel
ES470861A1 (es) Procedimiento de preparacion de derivados de benzoil-2 clo- ro-4 glicinanilidas
BE876701A (fr) Compositions stabilisees contenant des lactoproteines
IT7922664A0 (it) Derivati di-o-n-alchilici della glicerina come stimolanti di immunita'.
FR2292428A1 (fr) Compositions fongicides contenant des diaryloxy-triazolyl-o,n-acetals
FR2320052A1 (fr) Nouvelles compositions fongicides contenant des derives 1,2,4-triazoliques et des gibberellines
FI822099A0 (fi) Maettade aminocyklitderivat, deras framstaellning och dessa innehaollande laekemedel
EP0018417A4 (en) New piperidine derivatives and pharmaceutical compositions containing them.
IT1057961B (it) Scatola per cerniera per mobili
IL50263A (en) 4-(2-benzoyloxy or phenoxyalkanoyl-oxy-3-tert-butylaminopropoxy)indole derivatives,their production and pharmaceutical compositions containing them
BE820701A (fr) Nouvelles compositions antimicrobiennes contenant des derives 1-propyl-triazolyliques
BE888238A (fr) Compositions stabilisees contenant des derives n-aminosulfenyles du carbofuranne,
AR002259A1 (es) Derivados de 1-oxo-2-(fenilsulfonilamino)pentilpiperidina, su preparacion, compuestos intermedios y composicion que contiene a dichos derivados.
ES462862A1 (es) Un procedimiento para preparar una composicion de aril-hi- drazonas con propiedades biocidas.