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ES470861A1 - Procedimiento de preparacion de derivados de benzoil-2 clo- ro-4 glicinanilidas - Google Patents

Procedimiento de preparacion de derivados de benzoil-2 clo- ro-4 glicinanilidas

Info

Publication number
ES470861A1
ES470861A1 ES470861A ES470861A ES470861A1 ES 470861 A1 ES470861 A1 ES 470861A1 ES 470861 A ES470861 A ES 470861A ES 470861 A ES470861 A ES 470861A ES 470861 A1 ES470861 A1 ES 470861A1
Authority
ES
Spain
Prior art keywords
glycinanilides
benzoyl
chloro
preparation
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES470861A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Publication of ES470861A1 publication Critical patent/ES470861A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)

Abstract

Procedimiento de preparación de derivados de benzoil-2 cloro-4 glicinanilidas, que responden a la fórmula general I: **(Fórmula)** en la cual: R representa un átomo de hidrógeno, un grupo alcohilo, alcanilo, alcinilo, alcoilamino, o -CH2-cicloalcoilo de 3 a 6 eslabones; R1 y R2 pueden ser idénticos o diferentes y se eligen entre los grupos alcohilo, hidroxialcoilo, alcoxialcoilo, aciloxialcoilo, arilo, aralcoilo eventualmente substituido una o varias veces por un radical alcoxi, alcenilo, alcinilo, eventualmente substituido una o varias veces por un radical alcohilo inferior, alcilamino, cicloalcoilo de 3 a 6 eslabones y eventualmente substituido sobre el carbono en alfa por un radical alcinilo, los heterociclos saturados.
ES470861A 1977-06-16 1978-06-16 Procedimiento de preparacion de derivados de benzoil-2 clo- ro-4 glicinanilidas Expired ES470861A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7718511A FR2403330A1 (fr) 1977-06-16 1977-06-16 Nouveaux derives de benzoyl-2-chloro-4-glycinanilides substitues, leur procede de preparation et leur application en tant que medicaments

Publications (1)

Publication Number Publication Date
ES470861A1 true ES470861A1 (es) 1979-02-01

Family

ID=9192181

Family Applications (1)

Application Number Title Priority Date Filing Date
ES470861A Expired ES470861A1 (es) 1977-06-16 1978-06-16 Procedimiento de preparacion de derivados de benzoil-2 clo- ro-4 glicinanilidas

Country Status (9)

Country Link
US (1) US4372975A (es)
EP (1) EP0000299B1 (es)
JP (1) JPS5436238A (es)
CA (1) CA1124256A (es)
DE (1) DE2860270D1 (es)
ES (1) ES470861A1 (es)
FR (1) FR2403330A1 (es)
IT (1) IT1156820B (es)
ZA (1) ZA783410B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2436776A1 (fr) * 1978-09-25 1980-04-18 Fabre Sa Pierre Nouveaux derives d'ortho chloro benzoyl-2 chloro-4 glycylanilide, leur preparation et leur application en tant que medicaments
FR2449677B1 (fr) * 1979-02-26 1986-03-28 Fabre Sa Pierre Nouveaux derives de benzoyl-2 glycylanilides substitues, leur preparation et leur application en tant que medicaments anxiolytiques
FR2459793A1 (fr) * 1979-06-25 1981-01-16 Fabre Sa Pierre Nouveaux derives de benzoyl-2 nitro-4 anilides, leur preparation et leur application en tant que medicaments
FR2492818B1 (fr) * 1980-10-28 1988-03-04 Fabre Sa Pierre Ortho halogeno benzoyl-2 halogeno-4 glycylanilides substitues, leur preparation et leur application comme medicaments
FR2552083B1 (fr) * 1983-09-15 1986-05-09 Cerm Cent Europ Rech Mauvernay Derives de (alkynyloxy-3 hydroxy-2-propyl)-4 piperazinyl-1 n-phenyl acetamide, leur preparation et leur application en therapeutique
DE4312778C3 (de) * 1993-04-20 2001-10-25 Vossloh Schwabe Gmbh Elektrische Anschlußklemmeinrichtung
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
CA2485681C (en) 2002-05-24 2012-10-16 Millennium Pharmaceuticals, Inc. Ccr9 inhibitors and methods of use thereof
US20070021466A1 (en) * 2002-11-18 2007-01-25 Solomon Ungashe CCR2 inhibitors and methods of use thereof
US7227035B2 (en) * 2002-11-18 2007-06-05 Chemocentryx Bis-aryl sulfonamides
US20060111351A1 (en) * 2002-11-18 2006-05-25 Solomon Ungashe Aryl sulfonamides
ATE363470T1 (de) * 2002-11-18 2007-06-15 Chemocentryx Inc Arylsulfonamide
US7420055B2 (en) 2002-11-18 2008-09-02 Chemocentryx, Inc. Aryl sulfonamides
US7741519B2 (en) * 2007-04-23 2010-06-22 Chemocentryx, Inc. Bis-aryl sulfonamides
CN105001105A (zh) * 2015-06-26 2015-10-28 华中药业股份有限公司 一种2-甲氨基-5-氯二苯甲酮的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK104746C (da) * 1960-06-27 1966-06-27 Hoffmann La Roche Fremgangsmåde til fremstilling af 2-α-aminoalkanoylamido-benzophenon-forbindelser eller syreadditionssalte eller kvaternære ammoniumforbindelser deraf.
US3202699A (en) * 1961-07-11 1965-08-24 Hoffmann La Roche Carbobenzoxyglycylamino-benzophenones
US3914215A (en) * 1967-11-27 1975-10-21 Sankyo Co Benzodiazepine derivatives and process for preparing the same
BG17604A3 (bg) * 1968-07-01 1973-11-10 Sankyo Co Ltd Метод за получаване на бензодиазепинови производни
IL33103A (en) * 1968-10-18 1974-06-30 Sparamedica Ag Oxazolo benzodiazepines,their preparation and pharmaceutical compositions containing them
US3927010A (en) * 1969-10-17 1975-12-16 Hoffmann La Roche Diarylmethane derivatives and processes for their preparation
SE410732B (sv) * 1971-12-13 1979-10-29 Sumitomo Chemical Co Analogiforfarande for framstellning av anilidderivat med terapeutisk verkan
US3928415A (en) * 1973-05-08 1975-12-23 Cassella Farbwerke Mainkur Ag Benzophenone derivatives and process for their production II
AU471999B2 (en) 1973-08-10 1976-05-13 Sankyo Company Limited Substituted amino-acetylamino-benzophenone compounds
DE2356239A1 (de) * 1973-11-10 1975-05-15 Cassella Farbwerke Mainkur Ag Benzophenon-derivate und verfahren zu ihrer herstellung
JPS5139654A (ja) * 1974-09-27 1976-04-02 Sumitomo Chemical Co Aminoasetoaniridojudotai no shinkinaseizoho

Also Published As

Publication number Publication date
ZA783410B (en) 1979-06-27
EP0000299A1 (fr) 1979-01-10
FR2403330A1 (fr) 1979-04-13
IT1156820B (it) 1987-02-04
US4372975A (en) 1983-02-08
CA1124256A (fr) 1982-05-25
DE2860270D1 (en) 1981-02-05
IT7849859A0 (it) 1978-06-14
FR2403330B1 (es) 1982-11-05
JPS5436238A (en) 1979-03-16
EP0000299B1 (fr) 1980-11-12

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