ES462923A1 - Un procedimiento para la obtencion de una composicion de ba-citracina de cinc. - Google Patents
Un procedimiento para la obtencion de una composicion de ba-citracina de cinc.Info
- Publication number
- ES462923A1 ES462923A1 ES462923A ES462923A ES462923A1 ES 462923 A1 ES462923 A1 ES 462923A1 ES 462923 A ES462923 A ES 462923A ES 462923 A ES462923 A ES 462923A ES 462923 A1 ES462923 A1 ES 462923A1
- Authority
- ES
- Spain
- Prior art keywords
- bacitracin
- zinc
- feed supplement
- composition
- zinc bacitracin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010001478 Bacitracin Proteins 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 6
- UCRLQOPRDMGYOA-DFTDUNEMSA-L zinc;(4r)-4-[[(2s)-2-[[(4r)-2-[(1s,2s)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2s,3s)-1-[[(3s,6r,9s,12r,15s,18r,21s)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2s)-butan-2-yl]-6-(carbox Chemical compound [Zn+2].C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2NC=NC=2)C(=O)N[C@H](CC([O-])=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 UCRLQOPRDMGYOA-DFTDUNEMSA-L 0.000 title abstract 4
- 239000006052 feed supplement Substances 0.000 title abstract 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 2
- 229960003071 bacitracin Drugs 0.000 abstract 2
- 229930184125 bacitracin Natural products 0.000 abstract 2
- CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 abstract 2
- 229910000019 calcium carbonate Inorganic materials 0.000 abstract 1
- 239000012876 carrier material Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 239000012798 spherical particle Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
- -1 zinc cations Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Birds (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Feed For Specific Animals (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Un procedimiento para la obtención de una composición de bacitracina de zinc con una estabilidad mejorada adecuada para empleo en piensos para animales que incluye precipitar bacitracina de zinc a partir de un caldo de fermentación, ajustar el pH del caldo de fermentación con álcali dentro del intervalo de 6,0 a 7,0, separar el agua para proporcionar una suspensión que contiene entre aproximadamente 10-35 preferiblemente 25 a 35% en peso de materia seca, añadir aproximadamente 50 a 100% en peso basado en la materia seca de la suspensión de un vehículo finamente dividido, en el que el 80% en peso de las partículas que forman el vehículo tienen una dimensión por debajo de 40 micras, mezclar la mezcla para dispersar uniformemente las partículas del vehículo, secar por pulverización dicha dispersión uniforme a una temperatura entre aproximadamente 300º a 450ºC, de modo que el agua se separe fácilmente para producir partículas sustancialmente esféricas y finamente divididas que contienen la bacitracina de zinc en contacto íntimo con el vehículo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/730,092 US4096246A (en) | 1976-10-06 | 1976-10-06 | Zinc bacitracin composition for use as a feed supplement and method for making the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES462923A1 true ES462923A1 (es) | 1978-07-16 |
Family
ID=24933869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462923A Expired ES462923A1 (es) | 1976-10-06 | 1977-10-05 | Un procedimiento para la obtencion de una composicion de ba-citracina de cinc. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4096246A (es) |
| JP (1) | JPS5362679A (es) |
| AR (1) | AR216489A1 (es) |
| AU (1) | AU512180B2 (es) |
| BE (1) | BE859438A (es) |
| CA (1) | CA1099640A (es) |
| CS (1) | CS196391B2 (es) |
| DE (1) | DE2745035A1 (es) |
| DK (1) | DK147651C (es) |
| ES (1) | ES462923A1 (es) |
| FI (1) | FI61789C (es) |
| FR (1) | FR2366800A1 (es) |
| GB (1) | GB1575126A (es) |
| HU (1) | HU178419B (es) |
| IE (1) | IE45708B1 (es) |
| IL (1) | IL53066A (es) |
| IT (1) | IT1088851B (es) |
| LU (1) | LU78264A1 (es) |
| MX (1) | MX4733E (es) |
| NL (1) | NL7710984A (es) |
| NO (1) | NO144815C (es) |
| PL (1) | PL104611B1 (es) |
| SE (1) | SE425046B (es) |
| YU (1) | YU41570B (es) |
| ZA (1) | ZA775986B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4164572A (en) * | 1976-10-06 | 1979-08-14 | A/S Apothekernes Laboratorium For Specialpraeparater | Zinc bacitracin composition for use as a feed supplement and method for making the same |
| DE3422782A1 (de) * | 1984-06-20 | 1986-01-02 | Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim | Zinkbacitracin enthaltender futtermittelzusatz |
| DE3725946A1 (de) * | 1987-08-05 | 1989-02-16 | Boehringer Ingelheim Vetmed | Stabilisierter futtermittelzusatz und verfahren zu seiner herstellung |
| DK0765157T3 (da) * | 1994-06-15 | 1999-10-25 | Dumex Ltd As | Pellets |
| US5958458A (en) * | 1994-06-15 | 1999-09-28 | Dumex-Alpharma A/S | Pharmaceutical multiple unit particulate formulation in the form of coated cores |
| CN106359898A (zh) * | 2016-08-30 | 2017-02-01 | 齐鲁制药(内蒙古)有限公司 | 一种杆菌肽锌预混剂的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2739063A (en) * | 1951-08-29 | 1956-03-20 | Commercial Solvents Corp | Bacitracin feed supplements from crude fermentation liquors |
| US2809892A (en) * | 1954-11-01 | 1957-10-15 | Commerical Solvents Corp | Zinc bacitracin feed supplement |
| US3019109A (en) * | 1960-05-10 | 1962-01-30 | American Cyanamid Co | Stabilization of antibiotics in feeds and feed supplements |
| US3116207A (en) * | 1961-06-07 | 1963-12-31 | Commercial Solvents Corp | Process for the protection of textiles |
| US3345178A (en) * | 1963-10-18 | 1967-10-03 | Dawe S Lab Inc | Precipitation of bacitracin upon an inert, insoluble, inorganic support for use in animal feeds |
| GB1182759A (en) * | 1967-06-21 | 1970-03-04 | Commercial Solvents Corp | Improvements in or relating to the production of Mixtures of Cycloserine and O-Carbamyl-D-Serine |
| GB1209634A (en) * | 1967-06-29 | 1970-10-21 | Rit Rech Ind Therapeut | Stabilized antibiotic compositions for animal feeding and process for preparing them |
-
1976
- 1976-10-06 US US05/730,092 patent/US4096246A/en not_active Expired - Lifetime
-
1977
- 1977-10-05 CS CS776451A patent/CS196391B2/cs unknown
- 1977-10-05 IT IT28303/77A patent/IT1088851B/it active
- 1977-10-05 SE SE7711158A patent/SE425046B/xx not_active IP Right Cessation
- 1977-10-05 DK DK440277A patent/DK147651C/da not_active IP Right Cessation
- 1977-10-05 NO NO773397A patent/NO144815C/no unknown
- 1977-10-05 ES ES462923A patent/ES462923A1/es not_active Expired
- 1977-10-05 CA CA288,187A patent/CA1099640A/en not_active Expired
- 1977-10-05 MX MX776457U patent/MX4733E/es unknown
- 1977-10-05 FR FR7729965A patent/FR2366800A1/fr active Granted
- 1977-10-05 GB GB41476/77A patent/GB1575126A/en not_active Expired
- 1977-10-05 YU YU2382/77A patent/YU41570B/xx unknown
- 1977-10-06 PL PL1977201332A patent/PL104611B1/pl unknown
- 1977-10-06 LU LU78264A patent/LU78264A1/xx unknown
- 1977-10-06 DE DE19772745035 patent/DE2745035A1/de not_active Withdrawn
- 1977-10-06 AU AU29418/77A patent/AU512180B2/en not_active Expired
- 1977-10-06 JP JP11954877A patent/JPS5362679A/ja active Pending
- 1977-10-06 AR AR269481A patent/AR216489A1/es active
- 1977-10-06 FI FI772951A patent/FI61789C/fi not_active IP Right Cessation
- 1977-10-06 IL IL53066A patent/IL53066A/xx unknown
- 1977-10-06 NL NL7710984A patent/NL7710984A/xx not_active Application Discontinuation
- 1977-10-06 HU HU77AO453A patent/HU178419B/hu unknown
- 1977-10-06 ZA ZA00775986A patent/ZA775986B/xx unknown
- 1977-10-06 BE BE181502A patent/BE859438A/xx not_active IP Right Cessation
- 1977-10-16 IE IE2041/77A patent/IE45708B1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990201 |