[go: up one dir, main page]

ES458957A1 - PROCEDURE FOR THE PREPARATION OF NEW 1-ARYLOXI-2-HI-DROXI-3-AMINOPROPANES. - Google Patents

PROCEDURE FOR THE PREPARATION OF NEW 1-ARYLOXI-2-HI-DROXI-3-AMINOPROPANES.

Info

Publication number
ES458957A1
ES458957A1 ES458957A ES458957A ES458957A1 ES 458957 A1 ES458957 A1 ES 458957A1 ES 458957 A ES458957 A ES 458957A ES 458957 A ES458957 A ES 458957A ES 458957 A1 ES458957 A1 ES 458957A1
Authority
ES
Spain
Prior art keywords
aminopropanes
preparation
new
aryloxi
droxi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458957A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES458957A1 publication Critical patent/ES458957A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyridine Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevos 1-ariloxi-2-hidroxi-3-aminopropanos de la fórmula I *** en la que R1 y R1¿ son iguales o diferentes y representan hidrógeno, un radical alcohilo o alcoxi con 1-4 átomo de carbono, el grupo alilo, un átomo de halógeno o el grupo nitro, R2 significa un radical de ácido acrílico o un radical de nitrilo de ácido acrílico.Process for the preparation of new 1-aryloxy-2-hydroxy-3-aminopropanes of formula I *** in which R1 and R1¿ are the same or different and represent hydrogen, an alkyl or alkoxy radical with 1-4 carbon atoms. carbon, allyl group, halogen atom or nitro group, R2 means acrylic acid radical or acrylic acid nitrile radical.

ES458957A 1976-05-25 1977-05-19 PROCEDURE FOR THE PREPARATION OF NEW 1-ARYLOXI-2-HI-DROXI-3-AMINOPROPANES. Expired ES458957A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2623314A DE2623314C2 (en) 1976-05-25 1976-05-25 1-aryloxy-2-hydroxy-3-aminopropanes, processes for their preparation and pharmaceuticals containing them

Publications (1)

Publication Number Publication Date
ES458957A1 true ES458957A1 (en) 1978-07-16

Family

ID=5978907

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458957A Expired ES458957A1 (en) 1976-05-25 1977-05-19 PROCEDURE FOR THE PREPARATION OF NEW 1-ARYLOXI-2-HI-DROXI-3-AMINOPROPANES.

Country Status (18)

Country Link
JP (1) JPS5312827A (en)
AT (1) AT354421B (en)
AU (1) AU511704B2 (en)
BE (1) BE855041A (en)
CA (1) CA1108633A (en)
CH (5) CH637105A5 (en)
DE (1) DE2623314C2 (en)
DK (1) DK227177A (en)
ES (1) ES458957A1 (en)
FI (1) FI67698C (en)
FR (1) FR2353520A1 (en)
GB (1) GB1577670A (en)
HU (1) HU179198B (en)
IL (1) IL52148A (en)
IT (1) IT1077193B (en)
NL (1) NL7705587A (en)
SE (1) SE440903B (en)
ZA (1) ZA773120B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2415622A1 (en) * 1978-01-25 1979-08-24 Lipha AMINO ALCOHOLS DERIVED FROM METHYL ORTHO-HYDROXY CINNAMATE APPLICABLE ESPECIALLY AS MEDICINAL PRODUCTS
DE2824764A1 (en) * 1978-06-06 1979-12-20 Hoechst Ag NEW PYRIDYL PIPERAZINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION
DE2961251D1 (en) * 1978-08-15 1982-01-14 Smithkline Beckman Corp A method of preparing a 2-hydroxy-3-isopropyl or a 2-hydroxy-3-tert-butylaminopropyl aromatic ether
FR2459235A1 (en) * 1979-06-14 1981-01-09 Sanofi Sa NOVEL SULFONYL-ANILINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
JPH0629833B2 (en) * 1984-06-15 1994-04-20 株式会社島津製作所 Fatigue testing machine
GB8603120D0 (en) * 1986-02-07 1986-03-12 Pfizer Ltd Anti-dysrhythmia agents
ES2244438T3 (en) 1999-05-24 2005-12-16 Mitsubishi Pharma Corporation PHENOXYPROPYLAMINE COMPOUNDS.
DE19941657A1 (en) * 1999-09-01 2001-03-08 Schwabe Willmar Gmbh & Co Cinnamic acid nitriles, process for their preparation and use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
FR2132570B1 (en) * 1971-04-09 1974-08-02 Lipha
BE791650R (en) * 1971-11-18 1973-05-21 Ici Ltd ALKANOLAMINE DERIVATIVES.
ES411826A1 (en) * 1973-02-20 1976-01-01 Liade Sa Lab Process for preparing pharmacologically active 1-aryloxy-2- propanolamines

Also Published As

Publication number Publication date
JPS5312827A (en) 1978-02-04
AU511704B2 (en) 1980-09-04
FR2353520B1 (en) 1980-07-25
DE2623314A1 (en) 1977-12-08
FI67698C (en) 1985-05-10
AT354421B (en) 1979-01-10
CH637107A5 (en) 1983-07-15
FR2353520A1 (en) 1977-12-30
JPS6214545B2 (en) 1987-04-02
CH640507A5 (en) 1984-01-13
IT1077193B (en) 1985-05-04
CH637109A5 (en) 1983-07-15
DK227177A (en) 1977-11-26
ZA773120B (en) 1978-04-26
CA1108633A (en) 1981-09-08
GB1577670A (en) 1980-10-29
ATA370177A (en) 1979-06-15
FI771630A7 (en) 1977-11-26
HU179198B (en) 1982-09-28
IL52148A (en) 1982-07-30
DE2623314C2 (en) 1984-08-02
AU2543477A (en) 1978-11-30
SE7706059L (en) 1977-11-26
FI67698B (en) 1985-01-31
BE855041A (en) 1977-11-25
CH637105A5 (en) 1983-07-15
CH637108A5 (en) 1983-07-15
SE440903B (en) 1985-08-26
NL7705587A (en) 1977-11-29
IL52148A0 (en) 1977-07-31

Similar Documents

Publication Publication Date Title
ES455149A1 (en) PROCEDURE FOR PREPARING N-PHENYL-N'-BENZOIL-UREAS.
ES470155A1 (en) A PROCEDURE FOR OBTAINING SPIROAMINE DERIVATIVES
ES470781A1 (en) 1-(4-Acylamino-phenyl)-2-amino-ethanols and salts thereof
ES463407A1 (en) PROCEDURE FOR THE PREPARATION OF NEW SUBSTITUTED FLUORACIL-RESOR-CINAS.
ES465525A1 (en) PROCEDURE FOR OBTAINING NEW PHENYLETHYLAMINES.
ES458957A1 (en) PROCEDURE FOR THE PREPARATION OF NEW 1-ARYLOXI-2-HI-DROXI-3-AMINOPROPANES.
BG28068A3 (en) METHOD FOR OBTAINING -3- CHLORCEPHALOSPORINS
BG28849A3 (en) METHOD OF OBTAINING GAMAPYRONES
ES452971A1 (en) 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-1,4-diazepines
ES458807A1 (en) A PROCEDURE FOR PREPARING PHENYLALKANOYLAMINES.
BG30475A3 (en) METHOD FOR OBTAINING DEPOSTEROID ESTERS
BG31073A3 (en) METHOD FOR PREPARATION OF 1,5-SUBSTITUTED-2-PYRROLIDONES
ES471254A1 (en) PROCEDURE FOR THE PREPARATION OF NEW IMIDAZO-ISOQUI- NOLEIN-DIONAS
SE7408826L (en)
ES462890A1 (en) PROCEDURE FOR THE PREPARATION OF 1- (N-ACIL-CARBAMOIL) -2-CYANAZI-RIDINS WITH CANCEROSTATIC EFFECT AND IMMUNITY STIMULATOR.
ES394322A1 (en) PROCEDURE FOR THE PREPARATION OF SUBSTITUTED 2-BENZYPHENOLS.
FR2319703A1 (en) NEW LUBRICATING COMPOSITIONS WITH IMPROVED ANTI-WEAR PROPERTIES
ES457563A1 (en) Dipeptide derivatives
BG33283A3 (en) METHOD FOR PREPARING PYRIDAZINYLHYDRAZONES
ES292885A1 (en) Procedure for preparing 4-desdimethylamin-4-substitute-amino-6-desmetiltetraciclines (Machine-translation by Google Translate, not legally binding)
ES357870A1 (en) PROCEDURE FOR THE PREPARATION OF BENZODIA-CEPINE DERIVATIVES.
BG28062A3 (en) Method of obtaining of 6a,10a, cishexahydrodibenzopyranones
ES462005A1 (en) Phenylalkylamino-alkyl derivatives of quinazolinone and phthalazinone
BG28057A4 (en) METHOD FOR OBTAINING 3-HYDROXYLETHYLENCHROMANOLS
ES454299A1 (en) PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 3-NITROPI-RAZOL.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990201