ES456639A1 - Un procedimiento de preparacion de los derivados del ciclo- penta (b) tiofeno. - Google Patents
Un procedimiento de preparacion de los derivados del ciclo- penta (b) tiofeno.Info
- Publication number
- ES456639A1 ES456639A1 ES456639A ES456639A ES456639A1 ES 456639 A1 ES456639 A1 ES 456639A1 ES 456639 A ES456639 A ES 456639A ES 456639 A ES456639 A ES 456639A ES 456639 A1 ES456639 A1 ES 456639A1
- Authority
- ES
- Spain
- Prior art keywords
- cyclopenta
- thiophene derivatives
- lower alkyl
- hydrogen
- thiophene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003577 thiophenes Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- KVPBSBOTFRNKOM-UHFFFAOYSA-N 2h-cyclopenta[b]thiophene Chemical class C1=CC2=CCSC2=C1 KVPBSBOTFRNKOM-UHFFFAOYSA-N 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Un procedimiento de preparación de los derivados del ciclopenta{b} tiofeno de fórmula: **(fórmula)** donde R{sub,1} representa un radical alquilo inferior, de cadena lineal o ramificada, de 1 a 4 átomos de carbono, principalmente etilo o isopropilo, R{sub,2} representa un átomo de hidrógeno o un radical alquilo inferior de 1 a 4 átomos de carbono, principalmente metilo, R{sub,3} representa un átomo de hidrógeno o un radical alquilo inferior de 1 a 4 átomos de carbono o un grupo aminoalquilo inferior.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB10049/76A GB1544963A (en) | 1976-03-12 | 1976-03-12 | Cyclopenta(b)thiophene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES456639A1 true ES456639A1 (es) | 1978-02-01 |
Family
ID=9960512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES456639A Expired ES456639A1 (es) | 1976-03-12 | 1977-03-08 | Un procedimiento de preparacion de los derivados del ciclo- penta (b) tiofeno. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4122091A (es) |
| JP (1) | JPS52111561A (es) |
| AR (1) | AR212755A1 (es) |
| AT (1) | ATA160977A (es) |
| AU (1) | AU506384B2 (es) |
| BE (1) | BE852375A (es) |
| DD (1) | DD129909A5 (es) |
| DE (1) | DE2709295A1 (es) |
| DK (1) | DK106377A (es) |
| ES (1) | ES456639A1 (es) |
| FR (1) | FR2346348A1 (es) |
| GB (1) | GB1544963A (es) |
| NL (1) | NL7702681A (es) |
| NO (1) | NO770864L (es) |
| PT (1) | PT66276B (es) |
| SE (1) | SE7702166L (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| FR2578845B1 (fr) * | 1985-03-12 | 1987-05-22 | Roussel Uclaf | Nouveaux derives de l'acide thiophene acetique, leur procede de preparation, les intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant |
| IT1404379B1 (it) * | 2011-02-11 | 2013-11-22 | Lembo | Eterocicli ad attivita' antiipertensiva |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH540247A (de) * | 1967-04-21 | 1973-09-28 | Ciba Geigy Ag | Verfahren zur Herstellung von heterocyclischen, Asthylendoppelbindungen enthaltenden Verbindungen |
| SE7411096L (es) * | 1973-09-11 | 1975-03-12 | Sandoz Ag |
-
1976
- 1976-03-12 GB GB10049/76A patent/GB1544963A/en not_active Expired
-
1977
- 1977-02-17 FR FR7704599A patent/FR2346348A1/fr active Granted
- 1977-02-28 SE SE7702166A patent/SE7702166L/xx unknown
- 1977-03-03 DE DE19772709295 patent/DE2709295A1/de active Pending
- 1977-03-07 AR AR266767A patent/AR212755A1/es active
- 1977-03-08 US US05/775,534 patent/US4122091A/en not_active Expired - Lifetime
- 1977-03-08 ES ES456639A patent/ES456639A1/es not_active Expired
- 1977-03-08 PT PT66276A patent/PT66276B/pt unknown
- 1977-03-10 AU AU23150/77A patent/AU506384B2/en not_active Expired
- 1977-03-10 JP JP2658877A patent/JPS52111561A/ja active Pending
- 1977-03-10 AT AT160977A patent/ATA160977A/de not_active IP Right Cessation
- 1977-03-11 NO NO770864A patent/NO770864L/no unknown
- 1977-03-11 DK DK106377A patent/DK106377A/da unknown
- 1977-03-11 BE BE2055728A patent/BE852375A/xx unknown
- 1977-03-11 NL NL7702681A patent/NL7702681A/xx not_active Application Discontinuation
- 1977-03-14 DD DD7700197843A patent/DD129909A5/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7702681A (nl) | 1977-09-14 |
| BE852375A (fr) | 1977-07-01 |
| FR2346348B1 (es) | 1978-11-03 |
| SE7702166L (sv) | 1977-09-13 |
| AU2315077A (en) | 1978-09-14 |
| DD129909A5 (de) | 1978-02-15 |
| JPS52111561A (en) | 1977-09-19 |
| AU506384B2 (en) | 1979-12-20 |
| AR212755A1 (es) | 1978-09-29 |
| US4122091A (en) | 1978-10-24 |
| DE2709295A1 (de) | 1977-09-15 |
| FR2346348A1 (fr) | 1977-10-28 |
| PT66276A (fr) | 1977-04-01 |
| ATA160977A (de) | 1980-01-15 |
| PT66276B (fr) | 1978-08-08 |
| NO770864L (no) | 1977-09-13 |
| DK106377A (da) | 1977-09-13 |
| GB1544963A (en) | 1979-04-25 |
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