[go: up one dir, main page]

ES443459A1 - A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES443459A1
ES443459A1 ES443459A ES443459A ES443459A1 ES 443459 A1 ES443459 A1 ES 443459A1 ES 443459 A ES443459 A ES 443459A ES 443459 A ES443459 A ES 443459A ES 443459 A1 ES443459 A1 ES 443459A1
Authority
ES
Spain
Prior art keywords
translation
procedure
preparation
formula
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES443459A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/533,385 external-priority patent/US4000282A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES443459A1 publication Critical patent/ES443459A1/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A procedure for the preparation of new 3-cyanopyridine derivatives of the formula: **(See formula)** where R is isopropyl or tert-butyl and pharmaceutically acceptable acid addition salts thereof, the process of which consists of: a) hydrolyze a compound of formula: **(See formula)** and its pharmaceutically acceptable acid addition salts, the process of which is to hydrolyze a compound of the formula: **(See formula)** where R is isopropyl or tert-butyl and R1 is hydrogen or an aldehyde moiety. b) if desired, prepare said salts of (I) by treating the product obtained in the previous step with a pharmaceutically acceptable acid, using the portions of reagents that are suitable. (Machine-translation by Google Translate, not legally binding)
ES443459A 1974-12-16 1975-12-12 A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding) Expired ES443459A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/533,385 US4000282A (en) 1974-12-16 1974-12-16 2-(3-tert. butyl or isopropylamino-2-hydroxypropoxy)-3-cyanopyridines

Publications (1)

Publication Number Publication Date
ES443459A1 true ES443459A1 (en) 1977-08-01

Family

ID=24125731

Family Applications (3)

Application Number Title Priority Date Filing Date
ES443459A Expired ES443459A1 (en) 1974-12-16 1975-12-12 A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)
ES458429A Expired ES458429A1 (en) 1974-12-16 1977-05-02 A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)
ES458425A Expired ES458425A1 (en) 1974-12-16 1977-05-04 A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES458429A Expired ES458429A1 (en) 1974-12-16 1977-05-02 A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)
ES458425A Expired ES458425A1 (en) 1974-12-16 1977-05-04 A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)

Country Status (16)

Country Link
AT (1) ATA946575A (en)
CS (1) CS188983B2 (en)
DD (1) DD122527A5 (en)
DK (1) DK544875A (en)
EG (1) EG11860A (en)
ES (3) ES443459A1 (en)
FI (1) FI753382A7 (en)
HU (1) HU171489B (en)
IE (1) IE42373B1 (en)
IL (1) IL48611A0 (en)
NO (1) NO754088L (en)
NZ (1) NZ179476A (en)
PH (1) PH12275A (en)
RO (1) RO68167A (en)
SU (2) SU608473A3 (en)
ZA (1) ZA757804B (en)

Also Published As

Publication number Publication date
IL48611A0 (en) 1976-02-29
ZA757804B (en) 1977-07-27
SU608473A3 (en) 1978-05-25
NO754088L (en) 1976-06-17
FI753382A7 (en) 1976-06-17
ATA946575A (en) 1979-09-15
EG11860A (en) 1977-11-30
SU618040A3 (en) 1978-07-30
CS188983B2 (en) 1979-03-30
RO68167A (en) 1981-11-24
DK544875A (en) 1976-06-17
IE42373L (en) 1976-06-16
IE42373B1 (en) 1980-07-30
ES458425A1 (en) 1978-03-16
PH12275A (en) 1978-12-12
ES458429A1 (en) 1978-11-16
DD122527A5 (en) 1976-10-12
HU171489B (en) 1978-01-28
NZ179476A (en) 1978-03-06

Similar Documents

Publication Publication Date Title
ES394370A1 (en) Pharmacologically active 3-piperazinyl-carbonyloxy-2-pyridyl-isoindolin-1-ones
ES454085A1 (en) Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -noroximorphone new. (Machine-translation by Google Translate, not legally binding)
ES432334A1 (en) 11 amidoarukiru 44 suruhoniruupiperajinkagobutsunoseizoho
ES443459A1 (en) A procedure for the preparation of new derivatives of 3-cyanopyridines. (Machine-translation by Google Translate, not legally binding)
JPS52264A (en) Process for preparing novel isoxazole derivatives
ES404315A1 (en) Nitrosourea derivatives
ES444036A1 (en) Process for the preparation of 2-2-thienyl-ethylamine and derivatives thereof
ES298104A1 (en) Procedure for the preparation of new oxazolinic and tiazolinic derivatives with nematocide action (Machine-translation by Google Translate, not legally binding)
ES462843A1 (en) Compound and production thereof
ES446187A1 (en) Oxime ethers having anti-depressive activity
FI762309A7 (en)
ES444005A2 (en) Salts of 2-alkylthiazole-5-methanol derivatives
ES438695A1 (en) A procedure for the preparation of prostate acid derivatives. (Machine-translation by Google Translate, not legally binding)
ES364980A1 (en) A method for preparing new adamantan derivatives. (Machine-translation by Google Translate, not legally binding)
ES314496A1 (en) Procedure for the preparation of tiazolinic heterociclic derivatives. (Machine-translation by Google Translate, not legally binding)
ES451091A1 (en) Improvement concerning about organic compound
ES433723A1 (en) Procedure for obtaining a derivative of 2-pirrolidinone. (Machine-translation by Google Translate, not legally binding)
ES325448A1 (en) Procedure for producing 4-amino-5-halo-2-benzamide derivatives. (Machine-translation by Google Translate, not legally binding)
ES429817A1 (en) 6-trichloroacetamido-penicillanic acid derivatives and their preparation
ES433453A1 (en) Arylpiperazine derivatives of adenine
ES434751A1 (en) Pharmaceutically useful indanylpropionic acid derivatives
ES443210A1 (en) Process for preparing hydratropic acid and derivatives thereof and intermediates useful in the process
JPS51146481A (en) Process for preparing arabinofuranosylcytosine derivatives
ES403885A1 (en) A procedure for preparing derivatives substituted in n 'of N- (trimetoxy-3,4,5) cinamoil-piperazine. (Machine-translation by Google Translate, not legally binding)
ES410009A1 (en) Process for preparing 7-acylamino-3-substituted-3-cephem-4- carboxylic acid derivatives