ES432106A1 - Procedimiento para la preparacion de d-homo-20-cetopregna- nos. - Google Patents
Procedimiento para la preparacion de d-homo-20-cetopregna- nos.Info
- Publication number
- ES432106A1 ES432106A1 ES432106A ES432106A ES432106A1 ES 432106 A1 ES432106 A1 ES 432106A1 ES 432106 A ES432106 A ES 432106A ES 432106 A ES432106 A ES 432106A ES 432106 A1 ES432106 A1 ES 432106A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- carbon
- see formula
- ketopregnanes
- homo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2360443A DE2360443A1 (de) | 1973-11-30 | 1973-11-30 | D-homo-20-ketopregnane |
| DE19742445161 DE2445161A1 (de) | 1974-09-19 | 1974-09-19 | D-homo-20-ketopregnane ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES432106A1 true ES432106A1 (es) | 1976-11-01 |
Family
ID=25766200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432106A Expired ES432106A1 (es) | 1973-11-30 | 1974-11-20 | Procedimiento para la preparacion de d-homo-20-cetopregna- nos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4045574A (es) |
| JP (1) | JPS5084561A (es) |
| AT (1) | AT347611B (es) |
| CA (1) | CA1030522A (es) |
| CH (1) | CH618183A5 (es) |
| DD (1) | DD115659A5 (es) |
| DK (1) | DK134348C (es) |
| ES (1) | ES432106A1 (es) |
| FR (1) | FR2253512B1 (es) |
| GB (1) | GB1494097A (es) |
| IE (1) | IE40423B1 (es) |
| IL (1) | IL46153A (es) |
| NL (1) | NL7415577A (es) |
| SE (1) | SE408426B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4879316A (en) * | 1987-02-26 | 1989-11-07 | The University Of Tennessee Research Corporation | Interpenetrating polymer network ion exchange membranes and method for preparing same |
| US6787530B1 (en) | 1996-08-23 | 2004-09-07 | Monash University | Use of pregnane-diones as analgesic agents |
| ES2271636T3 (es) * | 2002-08-16 | 2007-04-16 | PHARMACIA & UPJOHN COMPANY LLC | Intermediarios de 5 androsten-3-ol esteroides y procedimientos para su preparacion. |
| US20070066579A1 (en) * | 2002-08-16 | 2007-03-22 | White Michael J | 5-androsten-3beta-ol steroid intermediates and processs for their preparation |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| BR112015026380A8 (pt) | 2013-04-17 | 2019-12-31 | Sage Therapeutics Inc | esteróides de c21-n-pirazolil 19-nor c3,3-dissubstituídos e métodos de uso destes |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| CN117304245A (zh) | 2013-04-17 | 2023-12-29 | 萨奇治疗股份有限公司 | 刺激神经活性的19-去甲类固醇及其使用方法 |
| AU2014290400B2 (en) | 2013-07-19 | 2019-12-05 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| EP3488852B1 (en) | 2013-08-23 | 2020-10-28 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| AU2015331597B2 (en) | 2014-10-16 | 2020-04-30 | Sage Therapeutics, Inc. | Compositions and methods for treating CNS disorders |
| CN117024502A (zh) | 2014-10-16 | 2023-11-10 | 萨奇治疗股份有限公司 | 靶向cns障碍的组合物和方法 |
| EP3719029A1 (en) | 2014-11-27 | 2020-10-07 | Sage Therapeutics, Inc. | Compositions for inducing sedation |
| DK3250210T3 (da) | 2015-01-26 | 2021-03-08 | Sage Therapeutics Inc | Sammensætninger og fremgangsmåder til behandling af cns-forstyrrelser |
| WO2016134301A2 (en) | 2015-02-20 | 2016-08-25 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| NZ749664A (en) | 2016-07-11 | 2025-08-29 | Sage Therapeutics Inc | C17, c20, and c21 substituted neuroactive steroids and their methods of use |
| JP7065825B2 (ja) | 2016-07-11 | 2022-05-12 | セージ セラピューティクス， インコーポレイテッド | Ｃ７、ｃ１２、およびｃ１６置換神経刺激性ステロイドおよびそれらの使用方法 |
| MA51316A (fr) * | 2017-12-22 | 2020-10-28 | Sage Therapeutics Inc | Compositions et méthodes permettant de traiter les troubles du snc |
| EP3902818A1 (en) | 2018-12-05 | 2021-11-03 | Sage Therapeutics, Inc. | Neuroactive steroids and their methods of use |
| KR102821994B1 (ko) | 2019-01-08 | 2025-06-19 | 쳉두 캉홍 파마슈티칼 코., 엘티디. | 스테로이드 화합물, 및 이의 용도와 제조방법 |
| AR119047A1 (es) | 2019-05-31 | 2021-11-17 | Sage Therapeutics Inc | Esteroides neuroactivos como moduladores de gabaa y su uso en el tratamiento de trastornos del snc |
| TWI896548B (zh) * | 2019-06-27 | 2025-09-11 | 美商賽吉醫療公司 | 用於治療cns病症之組合物及方法 |
| WO2020264495A1 (en) * | 2019-06-27 | 2020-12-30 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2860158A (en) * | 1954-10-18 | 1958-11-11 | Sterling Drug Inc | Compounds of the perhydrochrysene series and preparation thereof |
| US3686223A (en) * | 1968-12-26 | 1972-08-22 | Sterling Drug Inc | D-homoestratrienes |
| US3833621A (en) * | 1972-03-20 | 1974-09-03 | Richardson Merrell Inc | 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same |
-
1974
- 1974-11-20 ES ES432106A patent/ES432106A1/es not_active Expired
- 1974-11-20 DK DK604174A patent/DK134348C/da active
- 1974-11-25 GB GB51006/74A patent/GB1494097A/en not_active Expired
- 1974-11-27 AT AT950774A patent/AT347611B/de not_active IP Right Cessation
- 1974-11-28 SE SE7414960A patent/SE408426B/xx unknown
- 1974-11-28 IE IE2448/74A patent/IE40423B1/xx unknown
- 1974-11-28 DD DD182648A patent/DD115659A5/xx unknown
- 1974-11-28 CH CH1580574A patent/CH618183A5/de not_active IP Right Cessation
- 1974-11-29 IL IL46153A patent/IL46153A/xx unknown
- 1974-11-29 US US05/528,328 patent/US4045574A/en not_active Expired - Lifetime
- 1974-11-29 NL NL7415577A patent/NL7415577A/xx not_active Application Discontinuation
- 1974-11-29 JP JP49137657A patent/JPS5084561A/ja active Pending
- 1974-12-02 FR FR7439371A patent/FR2253512B1/fr not_active Expired
- 1974-12-02 CA CA215,097A patent/CA1030522A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AT347611B (de) | 1979-01-10 |
| SE7414960L (es) | 1975-06-02 |
| GB1494097A (en) | 1977-12-07 |
| DD115659A5 (es) | 1975-10-12 |
| IE40423L (en) | 1975-05-30 |
| DK604174A (es) | 1975-07-28 |
| ATA950774A (de) | 1978-05-15 |
| IL46153A (en) | 1979-01-31 |
| CA1030522A (en) | 1978-05-02 |
| NL7415577A (nl) | 1975-06-03 |
| FR2253512A1 (es) | 1975-07-04 |
| DK134348C (da) | 1977-03-21 |
| FR2253512B1 (es) | 1978-02-03 |
| IE40423B1 (en) | 1979-05-23 |
| IL46153A0 (en) | 1975-02-10 |
| SE408426B (sv) | 1979-06-11 |
| US4045574A (en) | 1977-08-30 |
| AU7586774A (en) | 1976-06-03 |
| JPS5084561A (es) | 1975-07-08 |
| CH618183A5 (es) | 1980-07-15 |
| DK134348B (da) | 1976-10-25 |
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