ES437411A1 - Dihydroxy phenyl benzyl ketone derivatives - Google Patents
Dihydroxy phenyl benzyl ketone derivativesInfo
- Publication number
- ES437411A1 ES437411A1 ES75437411A ES437411A ES437411A1 ES 437411 A1 ES437411 A1 ES 437411A1 ES 75437411 A ES75437411 A ES 75437411A ES 437411 A ES437411 A ES 437411A ES 437411 A1 ES437411 A1 ES 437411A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen
- carbon atoms
- methyl
- ketone derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PRSPQRYSDMXKSO-UHFFFAOYSA-N 1-(2,3-dihydroxyphenyl)-2-phenylethanone Chemical class OC1=CC=CC(C(=O)CC=2C=CC=CC=2)=C1O PRSPQRYSDMXKSO-UHFFFAOYSA-N 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 125000003158 alcohol group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- OTKCEEWUXHVZQI-UHFFFAOYSA-N 1,2-diphenylethanone Chemical class C=1C=CC=CC=1C(=O)CC1=CC=CC=C1 OTKCEEWUXHVZQI-UHFFFAOYSA-N 0.000 abstract 1
- 238000005618 Fries rearrangement reaction Methods 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000000010 aprotic solvent Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000005286 illumination Methods 0.000 abstract 1
- 239000011968 lewis acid catalyst Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- SUSQOBVLVYHIEX-UHFFFAOYSA-N phenylacetonitrile Chemical compound N#CCC1=CC=CC=C1 SUSQOBVLVYHIEX-UHFFFAOYSA-N 0.000 abstract 1
- -1 phenylacetyl Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedure for the preparation of phenylbenzyl ketone derivatives of the general formula I **(See formula)** (wherein R1 means a hydrogen atom or an alcohol group with 1 to 6 carbon atoms, and R2 means a hydrogen atom or an alcohol group with 1 to 20 carbon atoms unsubstituted or substituted by an alkoxy group with 1 to 6 carbon atoms, an OH group, a phenyl group or a halogen-phenyl group, provided that in the event that R2 means hydrogen, R1 cannot represent methyl or ethyl, and in the event that R2 means methyl, R1 cannot represent hydrogen, methyl or ethyl, characterized in that a compound of the general formula III is reacted **(See formula)** (where R1 and R2 have the above meanings, provided that at least one of these symbols is not hydrogen, or one of the symbols means hydrogen or an eventually substituted alcoholic group, as indicated above, and the other symbol means a phenylacetyl group), with benzyl cyanide in an aprotic solvent in the presence of an acid catalyst, or said compound is subjected to a Fries rearrangement in the presence of a Lewis acid catalyst or under illumination. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI1193A HU168744B (en) | 1971-12-02 | 1971-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES437411A1 true ES437411A1 (en) | 1977-01-01 |
Family
ID=10994424
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES408947A Expired ES408947A1 (en) | 1971-12-02 | 1972-11-24 | Dihydroxy phenyl benzyl ketone derivatives |
| ES75437411A Expired ES437411A1 (en) | 1971-12-02 | 1975-05-02 | Dihydroxy phenyl benzyl ketone derivatives |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES408947A Expired ES408947A1 (en) | 1971-12-02 | 1972-11-24 | Dihydroxy phenyl benzyl ketone derivatives |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS4862746A (en) |
| AR (2) | AR209254A1 (en) |
| AT (1) | AT335424B (en) |
| ES (2) | ES408947A1 (en) |
| FR (1) | FR2162175B1 (en) |
| GB (1) | GB1374925A (en) |
| HU (1) | HU168744B (en) |
| SU (2) | SU501664A3 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0478559T3 (en) * | 1990-04-18 | 1996-02-19 | Chinoin Gyogyszer Es Vegyeszet | Improved method for making kentone compounds |
| JPH09301916A (en) * | 1996-05-14 | 1997-11-25 | Hoechst Japan Ltd | Polyhydroxyphenol derivatives and prophylactic / therapeutic agents comprising bone and cartilage diseases comprising them |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1525941A (en) * | 1966-01-14 | 1968-05-24 | Merck & Co Inc | Process for the manufacture of [(2-methylene-alkanoyl) phenoxy] alkanoic acids |
| CH513793A (en) * | 1968-05-15 | 1971-10-15 | Merck Patent Gmbh | Process for the preparation of diarylacylophenones |
-
1971
- 1971-12-02 HU HUCI1193A patent/HU168744B/hu unknown
-
1972
- 1972-11-24 ES ES408947A patent/ES408947A1/en not_active Expired
- 1972-11-27 AT AT1006772A patent/AT335424B/en not_active IP Right Cessation
- 1972-11-28 AR AR245347A patent/AR209254A1/en active
- 1972-11-30 GB GB5537172A patent/GB1374925A/en not_active Expired
- 1972-12-01 FR FR7242849A patent/FR2162175B1/fr not_active Expired
- 1972-12-01 JP JP47120563A patent/JPS4862746A/ja active Pending
- 1972-12-02 SU SU1855104A patent/SU501664A3/en active
-
1973
- 1973-11-15 SU SU731969303A patent/SU731889A3/en active
-
1975
- 1975-04-04 AR AR258246A patent/AR210466A1/en active
- 1975-05-02 ES ES75437411A patent/ES437411A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES408947A1 (en) | 1976-04-16 |
| AT335424B (en) | 1977-03-10 |
| GB1374925A (en) | 1974-11-20 |
| AR209254A1 (en) | 1977-04-15 |
| HU168744B (en) | 1976-07-28 |
| FR2162175B1 (en) | 1976-04-23 |
| FR2162175A1 (en) | 1973-07-13 |
| AR210466A1 (en) | 1977-08-15 |
| ATA1006772A (en) | 1976-07-15 |
| SU731889A3 (en) | 1980-04-30 |
| JPS4862746A (en) | 1973-09-01 |
| SU501664A3 (en) | 1976-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES402057A1 (en) | Compounds tetracloroftalidos cromogenicos (Machine-translation by Google Translate, not legally binding) | |
| KR880013916A (en) | Method for producing β-D-phenylthioxillosides | |
| Sheradsky | The rearrangement of O-vinyloximes a new synthesis of substituted pyrroles | |
| ES437411A1 (en) | Dihydroxy phenyl benzyl ketone derivatives | |
| ES428295A1 (en) | Procedure for the obtaining of sulphonated canfene derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES403209A1 (en) | Novel acetophenone oxime derivatives | |
| KR870002115A (en) | Process for preparing 6-phenoxymethyl-4-hydroxy tetrahydropyran-2-one | |
| ES400841A1 (en) | 2-hydroxybenzophenones | |
| GB1259081A (en) | ||
| ES412047A1 (en) | Preparation of dihydrocoumarin and of alkyl derivatives thereof | |
| ES392355A1 (en) | D-homosteroid imides and a process for the preparation thereof | |
| ES389122A1 (en) | PROCEDURE FOR OBTAINING DIBENZOHETERO-CICLICOS DERIVATIVES. | |
| ES451697A1 (en) | Method for the preparation of 2-alkyl indanes | |
| ES402224A1 (en) | A PROCEDURE FOR THE PREPARATION OF ALPHA-ANILINOCARBONITRILES. | |
| ES415282A1 (en) | A procedure to prepare new aromatic esters. (Machine-translation by Google Translate, not legally binding) | |
| ES437041A1 (en) | A procedure for preparing 1-ftalazone derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES422248A1 (en) | Procedure for the preparation of 7-chlorine-1,2-dihydro-5-phenyl - 1,4-benzodiazepin-2-onas. (Machine-translation by Google Translate, not legally binding) | |
| ES402328A1 (en) | Preparation of 4-hydroxybenzodioxoles | |
| GB1470759A (en) | Process for the preparation of bis-hydroxyaryl-compounds | |
| ES373998A1 (en) | Procedure for the production of orthosethyled feniletilaminas. (Machine-translation by Google Translate, not legally binding) | |
| ES402471A1 (en) | A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 1-ARI-LOXI-3-AMINO-PROPANOL. | |
| ES435696A1 (en) | A method for the preparation of acid 3- (benzoil trisustituido) -propionico. (Machine-translation by Google Translate, not legally binding) | |
| KR840002774A (en) | Method for producing fluorophenoxybenzyl esters | |
| ES373486A1 (en) | New mixed acetals and process for the production of mixed acetals | |
| ES421341A1 (en) | Di-hydroxygenzenesulphonic acid salts |