ES446295A1 - Derivatives of salicylic acid suitable for use in therapeutics - Google Patents
Derivatives of salicylic acid suitable for use in therapeuticsInfo
- Publication number
- ES446295A1 ES446295A1 ES446295A ES446295A ES446295A1 ES 446295 A1 ES446295 A1 ES 446295A1 ES 446295 A ES446295 A ES 446295A ES 446295 A ES446295 A ES 446295A ES 446295 A1 ES446295 A1 ES 446295A1
- Authority
- ES
- Spain
- Prior art keywords
- salicylic acid
- chlorophenoxy
- therapeutics
- derivatives
- acid suitable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical class OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 150000007530 organic bases Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- MGCJZWTXXQEHHR-UHFFFAOYSA-N 3-(4-chlorophenoxy)-2-(2-methylpropanoyloxy)benzoic acid Chemical compound ClC1=CC=C(OC2=C(C(C(=O)O)=CC=C2)OC(C(C)C)=O)C=C1 MGCJZWTXXQEHHR-UHFFFAOYSA-N 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960004889 salicylic acid Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of 4-chlorophenoxy-isobutyryl-salicylic acid, of formula I: ** (See formula) ** as well as its salts with mineral and organic bases, in which the phenol function of salicylic acid is esterified by reaction with para-chlorophenoxy-isobutyric acid chloride or by reaction with the anhydride of said para-chlorophenoxy-isobutyric acid; and, optionally, the compound obtained is reacted with mineral or organic bases to produce the corresponding salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7509195A FR2305188A1 (en) | 1975-03-24 | 1975-03-24 | NEW DERIVATIVES OF SALICYLIC ACID, USED IN THERAPEUTICS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES446295A1 true ES446295A1 (en) | 1977-12-01 |
Family
ID=9153004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES446295A Expired ES446295A1 (en) | 1975-03-24 | 1976-03-23 | Derivatives of salicylic acid suitable for use in therapeutics |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE839959A (en) |
| CH (1) | CH610876A5 (en) |
| DE (1) | DE2612321A1 (en) |
| ES (1) | ES446295A1 (en) |
| FR (1) | FR2305188A1 (en) |
| GB (1) | GB1501074A (en) |
| LU (1) | LU74624A1 (en) |
| NL (1) | NL7603068A (en) |
| PT (1) | PT64940B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2730174C2 (en) * | 1977-07-04 | 1981-12-10 | Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren | Aminobenzoic acid derivatives and medicaments containing such aminobenzoic acid derivatives |
| US4615330A (en) * | 1983-09-05 | 1986-10-07 | Olympus Optical Co., Ltd. | Noise suppressor for electronic endoscope |
-
1975
- 1975-03-24 FR FR7509195A patent/FR2305188A1/en active Granted
-
1976
- 1976-03-23 LU LU74624A patent/LU74624A1/xx unknown
- 1976-03-23 DE DE19762612321 patent/DE2612321A1/en not_active Withdrawn
- 1976-03-23 ES ES446295A patent/ES446295A1/en not_active Expired
- 1976-03-24 NL NL7603068A patent/NL7603068A/en not_active Application Discontinuation
- 1976-03-24 CH CH365976A patent/CH610876A5/en not_active IP Right Cessation
- 1976-03-24 GB GB1190876A patent/GB1501074A/en not_active Expired
- 1976-03-24 PT PT6494076A patent/PT64940B/en unknown
- 1976-03-24 BE BE165500A patent/BE839959A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7603068A (en) | 1976-09-28 |
| GB1501074A (en) | 1978-02-15 |
| DE2612321A1 (en) | 1976-10-07 |
| PT64940A (en) | 1976-04-01 |
| FR2305188A1 (en) | 1976-10-22 |
| PT64940B (en) | 1977-08-25 |
| FR2305188B1 (en) | 1979-03-16 |
| CH610876A5 (en) | 1979-05-15 |
| BE839959A (en) | 1976-07-16 |
| LU74624A1 (en) | 1976-09-01 |
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