ES423985A1 - Procedure for the preparation of n, N-bis- (2- (3,4-dihydroxypenyl) -2-hydroxyethyl) -hexameethylendiamine and of its salts by addition of acid. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of n, N-bis- (2- (3,4-dihydroxypenyl) -2-hydroxyethyl) -hexameethylendiamine and of its salts by addition of acid. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES423985A1 ES423985A1 ES423985A ES423985A ES423985A1 ES 423985 A1 ES423985 A1 ES 423985A1 ES 423985 A ES423985 A ES 423985A ES 423985 A ES423985 A ES 423985A ES 423985 A1 ES423985 A1 ES 423985A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxyethyl
- bis
- translation
- salts
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- NAQMVNRVTILPCV-UHFFFAOYSA-N hexane-1,6-diamine Chemical compound NCCCCCCN NAQMVNRVTILPCV-UHFFFAOYSA-N 0.000 abstract 1
- OXLZNBCNGJWPRV-UHFFFAOYSA-N hexoprenaline Chemical compound C=1C=C(O)C(O)=CC=1C(O)CNCCCCCCNCC(O)C1=CC=C(O)C(O)=C1 OXLZNBCNGJWPRV-UHFFFAOYSA-N 0.000 abstract 1
- 150000004678 hydrides Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Procedure for the preparation of N, N'-bis- [2- (3,4-dihydroxyphenyl) -2-hydroxyethyl] -hexamethylenediamine and its salts by addition of acid, characterized in that 1,6-hexandiamine is condensed with a compound of the formula **(See formula)** wherein R means a protecting group capable of being separated by hydrogenolysis and R'means hydrogen or a lower alcohol radical, the compound obtained of the formula **(See formula)** it is reduced with a complex hydride, thereafter the protecting groups are removed in the usual way and the reaction product is subsequently optionally converted to the free base or a desired acid addition salt. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2312234A DE2312234A1 (en) | 1973-03-12 | 1973-03-12 | Hexamethylene-diamine derivs from 1,6-hexane-diamine - esp. N,N'-bis (2-(3,4-dihydroxyphenyl)-2-hydroxyethyl)- deriv |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES423985A1 true ES423985A1 (en) | 1976-05-01 |
Family
ID=5874542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES423985A Expired ES423985A1 (en) | 1973-03-12 | 1974-03-06 | Procedure for the preparation of n, N-bis- (2- (3,4-dihydroxypenyl) -2-hydroxyethyl) -hexameethylendiamine and of its salts by addition of acid. (Machine-translation by Google Translate, not legally binding) |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS49125326A (en) |
| DD (1) | DD112253A5 (en) |
| DE (1) | DE2312234A1 (en) |
| ES (1) | ES423985A1 (en) |
| NL (1) | NL7403216A (en) |
| SU (1) | SU504476A3 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6541669B1 (en) | 1998-06-08 | 2003-04-01 | Theravance, Inc. | β2-adrenergic receptor agonists |
| US6713651B1 (en) | 1999-06-07 | 2004-03-30 | Theravance, Inc. | β2-adrenergic receptor agonists |
| US6683115B2 (en) | 1999-06-02 | 2004-01-27 | Theravance, Inc. | β2-adrenergic receptor agonists |
| UA73965C2 (en) | 1999-12-08 | 2005-10-17 | Theravance Inc | b2 ADRENERGIC RECEPTOR ANTAGONISTS |
-
1973
- 1973-03-12 DE DE2312234A patent/DE2312234A1/en active Pending
-
1974
- 1974-03-06 ES ES423985A patent/ES423985A1/en not_active Expired
- 1974-03-07 SU SU2009792A patent/SU504476A3/en active
- 1974-03-11 JP JP49027992A patent/JPS49125326A/ja active Pending
- 1974-03-11 NL NL7403216A patent/NL7403216A/xx unknown
- 1974-03-12 DD DD177147A patent/DD112253A5/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7403216A (en) | 1974-09-16 |
| JPS49125326A (en) | 1974-11-30 |
| DD112253A5 (en) | 1975-04-05 |
| SU504476A3 (en) | 1976-02-25 |
| DE2312234A1 (en) | 1974-09-19 |
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