ES411562A1 - Procedure for the production of cumarine and cumarinimide compounds. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the production of cumarine and cumarinimide compounds. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES411562A1 ES411562A1 ES411562A ES411562A ES411562A1 ES 411562 A1 ES411562 A1 ES 411562A1 ES 411562 A ES411562 A ES 411562A ES 411562 A ES411562 A ES 411562A ES 411562 A1 ES411562 A1 ES 411562A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- formula
- compound
- defined above
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 6
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 4
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 2
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 2
- 125000004429 atom Chemical group 0.000 abstract 2
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N coumarin Chemical compound C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229960000956 coumarin Drugs 0.000 abstract 1
- 235000001671 coumarin Nutrition 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Process for the production of coumarin and coumarinimide compounds, of formula I, **(See formula)** wherein R1 signifies an unsubstituted or substituted alkyl or phenyl radical, said alkyl radical containing from 1 to 6 carbon atoms, R2 signifying a hydrogen atom or an unsubstituted or substituted alkyl or phenyl radical, said alkyl radical containing 1 to 6 carbon atoms, or R1 and R2, together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocyclic ring, saturated, partially saturated or unsaturated, means a hydrogen atom, an acyl radical, an organic ester radical, or an unsubstituted or substituted alkyl or phenyl radical, said acyl and alkyl radicals containing from 1 to 6 carbon atoms, R4 and R5, which may be the same or different, each signify an atom of hydrogen, an acyl radical, an organic acid ester radical, or an unsubstituted or substituted alkyl, phenyl, or heterocyclic radical, where the alkyl radical contains from 1 to 6 carbon atoms, the acyl radical contains from 1 to 6 atoms carbon, and the heterocyclic radical has 5 or 6 members, being saturated, partially saturated or unsaturated, or R4 and R5, together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocyclic ring, without substituted or substituted, saturated, partially saturated or unsaturated, and X means an oxygen atom or is = NH; characterized in that a compound of formula II is condensed, **(See formula)** wherein R1 and R2 are as defined above, with a compound of formula III, **(See formula)** wherein R3, R4 and R5 are as defined above, to provide a compound of the formula **(See formula)** wherein R1, R2, R3, R4 and R5 are as defined above, and, in case a compound of formula I is desired to be obtained, where X stands for an oxygen atom, the compound is hydrolyzed of formula Ib, as defined above, to provide a compound of formula Ic, **(See formula)** wherein R1, R2, R3, R4 and R5 are as defined above. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH218272A CH556375A (en) | 1972-02-15 | 1972-02-15 | PROCESS FOR THE PREPARATION IN WATER OF HARDLY SOLUBLE CUMARIN COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES411562A1 true ES411562A1 (en) | 1976-05-16 |
Family
ID=4227798
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES411562A Expired ES411562A1 (en) | 1972-02-15 | 1973-02-13 | Procedure for the production of cumarine and cumarinimide compounds. (Machine-translation by Google Translate, not legally binding) |
Country Status (8)
| Country | Link |
|---|---|
| BR (2) | BR7301084D0 (en) |
| CS (2) | CS166049B2 (en) |
| DD (1) | DD105442A5 (en) |
| ES (1) | ES411562A1 (en) |
| HU (2) | HU166003B (en) |
| IN (1) | IN141304B (en) |
| IT (1) | IT982857B (en) |
| ZA (2) | ZA731083B (en) |
-
1973
- 1973-02-13 ES ES411562A patent/ES411562A1/en not_active Expired
- 1973-02-13 HU HUSA002463 patent/HU166003B/hu unknown
- 1973-02-13 HU HUSA002461 patent/HU165841B/hu unknown
- 1973-02-13 DD DD16883673A patent/DD105442A5/xx unknown
- 1973-02-14 BR BR108473A patent/BR7301084D0/en unknown
- 1973-02-14 CS CS107973A patent/CS166049B2/cs unknown
- 1973-02-14 BR BR108073A patent/BR7301080D0/en unknown
- 1973-02-14 CS CS108073A patent/CS167373B2/cs unknown
- 1973-02-14 IT IT4823573A patent/IT982857B/en active
- 1973-02-15 ZA ZA731083A patent/ZA731083B/en unknown
- 1973-02-15 ZA ZA731084A patent/ZA731084B/en unknown
-
1974
- 1974-02-11 IN IN278/CAL/1974A patent/IN141304B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA731084B (en) | 1974-10-30 |
| DD105442A5 (en) | 1974-04-20 |
| ZA731083B (en) | 1974-09-25 |
| CS166049B2 (en) | 1976-01-29 |
| IT982857B (en) | 1974-10-21 |
| CS167373B2 (en) | 1976-04-29 |
| HU166003B (en) | 1974-12-28 |
| HU165841B (en) | 1974-11-28 |
| BR7301084D0 (en) | 1973-12-18 |
| BR7301080D0 (en) | 1973-12-18 |
| IN141304B (en) | 1977-02-12 |
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