ES402637A1 - Procedimiento para la preparacion de fenilaminoalcanos. - Google Patents
Procedimiento para la preparacion de fenilaminoalcanos.Info
- Publication number
- ES402637A1 ES402637A1 ES402637A ES402637A ES402637A1 ES 402637 A1 ES402637 A1 ES 402637A1 ES 402637 A ES402637 A ES 402637A ES 402637 A ES402637 A ES 402637A ES 402637 A1 ES402637 A1 ES 402637A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- halogen
- cmh2m
- cnh2n
- signifies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZFXYFBGIUFBOJW-UHFFFAOYSA-N theophylline Chemical compound O=C1N(C)C(=O)N(C)C2=C1NC=N2 ZFXYFBGIUFBOJW-UHFFFAOYSA-N 0.000 abstract 3
- 125000003277 amino group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002560 nitrile group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960000278 theophylline Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/32—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by introduction of halogenated alkyl groups into ring compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
- C07C205/08—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to acyclic carbon atoms
- C07C205/09—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
- C07C45/565—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procedimiento para la preparación de fenilaminoalcanos de la fórmula general I **fórmula** en la que Cl significa un átomo de cloro en posición 4 o 6, R1 y R2 significan hidrógeno o un grupo metilo, R4 significa hidrógeno , un radical alcohilo inferior, un grupo bencilo o teofilin (7)-etilo, o uno de los radicales -CnH2n-R5 (en que n significa 1 o 2 y R5 significa un grupo carboxilo, un grupo alcoxicarbonilo, un grupo aminocarbonilo o un grupo nitrilo), CmH2m- R6 o CmH2m-1(C6H5)-R6 (en que m significa 2, 3 o 4 , y R6 significa halógeno, un grupo hidroxilo, un grupo amino o un grupo acilamino),-CnH2n-CO-R (en que n significa 1 o 2; R significa un grupo alcohilo inferior o un grupo fenilo) o -CO-R7 (en que R7 significa un grupo alcoxi inferior, alcohiltio inferior o un grupo benciloxi o un radical alcohilo, que puede estar sustituido por un átomo de halógeno, un grupo hidroxilo o un grupo amino), así como sus formas ópticamente activas y/o sales con anión ácido fisiológicamente compatible),
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2021620A DE2021620C3 (de) | 1970-05-02 | 1970-05-02 | Neue Phenylaminoalkane und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES402637A1 true ES402637A1 (es) | 1975-12-16 |
Family
ID=5770113
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES390778A Expired ES390778A1 (es) | 1970-05-02 | 1971-04-30 | Un procedimiento para la fabricacion de fenilaminoalcanos. |
| ES402637A Expired ES402637A1 (es) | 1970-05-02 | 1972-05-12 | Procedimiento para la preparacion de fenilaminoalcanos. |
| ES402638A Expired ES402638A1 (es) | 1970-05-02 | 1972-05-12 | Procedimiento para la preparacion de fenilaminoalcanos. |
| ES402636A Expired ES402636A1 (es) | 1970-05-02 | 1972-05-12 | Procedimiento para la preparacion de fenilaminoalcanos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES390778A Expired ES390778A1 (es) | 1970-05-02 | 1971-04-30 | Un procedimiento para la fabricacion de fenilaminoalcanos. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES402638A Expired ES402638A1 (es) | 1970-05-02 | 1972-05-12 | Procedimiento para la preparacion de fenilaminoalcanos. |
| ES402636A Expired ES402636A1 (es) | 1970-05-02 | 1972-05-12 | Procedimiento para la preparacion de fenilaminoalcanos. |
Country Status (22)
| Country | Link |
|---|---|
| JP (4) | JPS5750773B1 (es) |
| AT (6) | AT317171B (es) |
| BE (1) | BE766654A (es) |
| BG (5) | BG21017A3 (es) |
| CH (4) | CH570968A5 (es) |
| CS (3) | CS170545B2 (es) |
| DE (1) | DE2021620C3 (es) |
| ES (4) | ES390778A1 (es) |
| FI (1) | FI53571C (es) |
| FR (1) | FR2092123B1 (es) |
| GB (1) | GB1354451A (es) |
| HU (1) | HU162545B (es) |
| IE (1) | IE35608B1 (es) |
| IL (1) | IL36743A (es) |
| NL (1) | NL169462C (es) |
| NO (1) | NO133708C (es) |
| PL (3) | PL91964B1 (es) |
| RO (5) | RO57821A (es) |
| SE (1) | SE374355B (es) |
| SU (2) | SU398031A3 (es) |
| YU (6) | YU35571B (es) |
| ZA (1) | ZA712788B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2239012A1 (de) * | 1972-08-08 | 1974-02-21 | Knoll Ag | Basisch substituierte theophyllinabkoemmlinge |
| EP0146067A3 (en) * | 1983-12-06 | 1987-03-04 | Merrell Dow Pharmaceuticals Inc. | Novel substrates for d-amino acid oxidase |
| JPS6314015U (es) * | 1986-07-11 | 1988-01-29 | ||
| JPS63136497A (ja) * | 1986-11-28 | 1988-06-08 | Hitachi Medical Corp | Ｘ線装置 |
| JPH0378128U (es) * | 1989-11-30 | 1991-08-07 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2029385A1 (es) * | 1969-01-27 | 1970-10-23 | Science Union & Cie |
-
1970
- 1970-05-02 DE DE2021620A patent/DE2021620C3/de not_active Expired
-
1971
- 1971-04-28 RO RO70104A patent/RO57821A/ro unknown
- 1971-04-28 SU SU1649251A patent/SU398031A3/ru active
- 1971-04-28 SU SU1820134A patent/SU440824A3/ru active
- 1971-04-28 RO RO7100070107A patent/RO62296A/ro unknown
- 1971-04-28 RO RO70106A patent/RO57681A/ro unknown
- 1971-04-28 RO RO66747A patent/RO57814A/ro unknown
- 1971-04-28 RO RO7100070105A patent/RO62418A/ro unknown
- 1971-04-29 CH CH29775A patent/CH570968A5/xx not_active IP Right Cessation
- 1971-04-29 CH CH29975A patent/CH579023A5/xx not_active IP Right Cessation
- 1971-04-29 CS CS3115A patent/CS170545B2/cs unknown
- 1971-04-29 CS CS722324A patent/CS194665B2/cs unknown
- 1971-04-29 CH CH632271A patent/CH561169A5/xx not_active IP Right Cessation
- 1971-04-29 CS CS2325A patent/CS175428B2/cs unknown
- 1971-04-29 CH CH29875A patent/CH579022A5/xx not_active IP Right Cessation
- 1971-04-29 NL NLAANVRAGE7105946,A patent/NL169462C/xx not_active IP Right Cessation
- 1971-04-29 YU YU1080/71A patent/YU35571B/xx unknown
- 1971-04-30 AT AT375071A patent/AT317171B/de active
- 1971-04-30 AT AT518673A patent/AT317176B/de not_active IP Right Cessation
- 1971-04-30 FR FR7115627A patent/FR2092123B1/fr not_active Expired
- 1971-04-30 BG BG22776A patent/BG21017A3/xx unknown
- 1971-04-30 IE IE545/71A patent/IE35608B1/xx unknown
- 1971-04-30 HU HUBO1290A patent/HU162545B/hu unknown
- 1971-04-30 BG BG019046A patent/BG21016A3/xx unknown
- 1971-04-30 PL PL1971177491A patent/PL91964B1/pl unknown
- 1971-04-30 NO NO1615/71A patent/NO133708C/no unknown
- 1971-04-30 BG BG017446A patent/BG18601A3/xx unknown
- 1971-04-30 BG BG019045A patent/BG19589A3/xx unknown
- 1971-04-30 IL IL36743A patent/IL36743A/xx unknown
- 1971-04-30 AT AT518573A patent/AT317175B/de not_active IP Right Cessation
- 1971-04-30 SE SE7105652A patent/SE374355B/xx unknown
- 1971-04-30 AT AT518473A patent/AT317174B/de active
- 1971-04-30 ZA ZA712788A patent/ZA712788B/xx unknown
- 1971-04-30 GB GB1244371A patent/GB1354451A/en not_active Expired
- 1971-04-30 ES ES390778A patent/ES390778A1/es not_active Expired
- 1971-04-30 BG BG019047A patent/BG19131A3/xx unknown
- 1971-04-30 FI FI1212/71A patent/FI53571C/fi active
- 1971-04-30 AT AT518273A patent/AT317172B/de not_active IP Right Cessation
- 1971-04-30 PL PL1971147865A patent/PL85189B1/pl unknown
- 1971-04-30 AT AT518373A patent/AT317173B/de not_active IP Right Cessation
- 1971-04-30 PL PL1971177492A patent/PL90714B1/pl unknown
- 1971-05-01 JP JP46029370A patent/JPS5750773B1/ja active Pending
- 1971-05-03 BE BE766654A patent/BE766654A/xx not_active IP Right Cessation
-
1972
- 1972-05-12 ES ES402637A patent/ES402637A1/es not_active Expired
- 1972-05-12 ES ES402638A patent/ES402638A1/es not_active Expired
- 1972-05-12 ES ES402636A patent/ES402636A1/es not_active Expired
-
1978
- 1978-10-26 YU YU2499/78A patent/YU36286B/xx unknown
- 1978-10-26 YU YU2498/78A patent/YU36285B/xx unknown
- 1978-10-26 YU YU02500/78A patent/YU36482B/xx unknown
-
1980
- 1980-06-16 YU YU1590/80A patent/YU37114B/xx unknown
- 1980-09-17 JP JP12902980A patent/JPS5655352A/ja active Granted
- 1980-09-17 JP JP12902780A patent/JPS5655350A/ja active Granted
- 1980-09-17 JP JP55129028A patent/JPS589090B2/ja not_active Expired
-
1981
- 1981-02-20 YU YU00433/81A patent/YU43381A/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19850206 |