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ES401263A1 - Penicillin synthesis - Google Patents

Penicillin synthesis

Info

Publication number
ES401263A1
ES401263A1 ES72401263A ES401263A ES401263A1 ES 401263 A1 ES401263 A1 ES 401263A1 ES 72401263 A ES72401263 A ES 72401263A ES 401263 A ES401263 A ES 401263A ES 401263 A1 ES401263 A1 ES 401263A1
Authority
ES
Spain
Prior art keywords
amino
penicillin
formula
acid
penicillin synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES72401263A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES401263A1 publication Critical patent/ES401263A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A process for the production of α-amino- (p-hydroxybenzyl) penicillin of formula (I): **(See formula)** and you get out of it; the procedure of which is to react a silylated derivative of 6-aminopenicilanic acid with a reactive derivative of α-amino-p-hydroxyphenylacetic acid in which the amino group is protected and then separate the silyl group or groups by hydrolysis or alcoholysis. (Machine-translation by Google Translate, not legally binding)
ES72401263A 1972-03-28 1972-03-28 Penicillin synthesis Expired ES401263A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB846071 1972-03-28

Publications (1)

Publication Number Publication Date
ES401263A1 true ES401263A1 (en) 1975-02-16

Family

ID=9852898

Family Applications (1)

Application Number Title Priority Date Filing Date
ES72401263A Expired ES401263A1 (en) 1972-03-28 1972-03-28 Penicillin synthesis

Country Status (2)

Country Link
ES (1) ES401263A1 (en)
GB (1) GB1339605A (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980637A (en) * 1975-03-17 1976-09-14 Bristol-Myers Company Production of amoxicillin
GB1532672A (en) * 1976-07-20 1978-11-15 Bristol Myers Co Process for the preparation of amoxicillin trihydrate
ES459494A1 (en) * 1977-06-04 1978-05-01 Palomo Coll A Luis Process for the preparation of hydroxy-alpha-amino-benzyl penicillin
NL162387C (en) * 1977-09-06 1980-05-16 Gist Brocades Nv PROCESS FOR PREPARING 6- (D-ALPHA-AMINO-P- HYDROXYPHENYLACETAMIDO) PENICILLANIC ACID.
US4278600A (en) 1979-03-19 1981-07-14 Bristol-Myers Company Production of penicillins
US4240960A (en) * 1979-03-19 1980-12-23 Bristol-Myers Company Trimethylsilyl substituted penicillins
US4310458A (en) 1979-03-19 1982-01-12 Bristol-Myers Company Production of penicillins
US4231954A (en) 1979-04-20 1980-11-04 American Home Products Corporation Dane salt and process for preparing aminopenicillins therefrom
US4351766A (en) * 1979-07-12 1982-09-28 Bristol-Myers Company Production of penicillins
DE3509618A1 (en) 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS A MEDICINAL PRODUCT
US7230097B2 (en) 2003-03-10 2007-06-12 Lupin Ltd. Process for preparation of 7-[α-Amino (4-hydroxyphenyl) acetamido]-3-substituted-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
GB1339605A (en) 1973-12-05

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