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ES409535A2 - PROCEDURE FOR THE PREPARATION OF N- (FUNYL-METHYL). MOR- FINANOS. - Google Patents

PROCEDURE FOR THE PREPARATION OF N- (FUNYL-METHYL). MOR- FINANOS.

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Publication number
ES409535A2
ES409535A2 ES409535A ES409535A ES409535A2 ES 409535 A2 ES409535 A2 ES 409535A2 ES 409535 A ES409535 A ES 409535A ES 409535 A ES409535 A ES 409535A ES 409535 A2 ES409535 A2 ES 409535A2
Authority
ES
Spain
Prior art keywords
formula
methyl
compound
hydrogen atom
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES409535A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Priority to ES409535A priority Critical patent/ES409535A2/en
Publication of ES409535A2 publication Critical patent/ES409535A2/en
Expired legal-status Critical Current

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Abstract

Improvements introduced in the object of the main patent No. 399,875, applied for on February 17, 1972, for: "Procedure for the preparation of N- (furyl-methyl) -morphonanes" of the general formula **(See formula)** wherein R signifies a hydrogen atom or a methyl or acetyl group and R1 signifies a hydrogen atom or a methyl or ethyl group, and their acid addition salts, characterized in that a quaternary ammonium salt of the formula **(See formula)** wherein R'and Z are as defined above, and R2 means an easy group to remove by Hofmann removal, preferably a phenethyl, naphthylethyl or 1,2-diphenylethyl group, and X means a halide or sulfonate anion, by treatment with alkalis, to form a compound of formula IV, and - if compounds of formula IV are obtained, in which Z does not have the meaning of R1, the substituent Z is transformed by chemical reaction into a hydrogen atom or in a methyl or ethyl group; and if desired - for the preparation of a compound of the formula I, in which R signifies a hydrogen atom, a compound of the formula is de-alcoholized or deacylated **(See formula)** wherein R1 has the meanings mentioned above and R'signifies an alcoholic, aralcohyl or acyl group; and if desired - for the preparation of a compound of the formula I, in which R means a methyl or acetyl group - a compound of the formula IVa is methylated or acetylated, in which R1 has the aforementioned meanings and R' designates a hydrogen atom, and eventually the compounds of the general formula I are transformed into their physiologically harmless acid addition salts. (Machine-translation by Google Translate, not legally binding)
ES409535A 1972-12-12 1972-12-12 PROCEDURE FOR THE PREPARATION OF N- (FUNYL-METHYL). MOR- FINANOS. Expired ES409535A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES409535A ES409535A2 (en) 1972-12-12 1972-12-12 PROCEDURE FOR THE PREPARATION OF N- (FUNYL-METHYL). MOR- FINANOS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES409535A ES409535A2 (en) 1972-12-12 1972-12-12 PROCEDURE FOR THE PREPARATION OF N- (FUNYL-METHYL). MOR- FINANOS.

Publications (1)

Publication Number Publication Date
ES409535A2 true ES409535A2 (en) 1976-12-16

Family

ID=8462868

Family Applications (1)

Application Number Title Priority Date Filing Date
ES409535A Expired ES409535A2 (en) 1972-12-12 1972-12-12 PROCEDURE FOR THE PREPARATION OF N- (FUNYL-METHYL). MOR- FINANOS.

Country Status (1)

Country Link
ES (1) ES409535A2 (en)

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20170704