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ES409217A1 - A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 5-NITROIMIDAZOLE. - Google Patents

A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 5-NITROIMIDAZOLE.

Info

Publication number
ES409217A1
ES409217A1 ES409217A ES409217A ES409217A1 ES 409217 A1 ES409217 A1 ES 409217A1 ES 409217 A ES409217 A ES 409217A ES 409217 A ES409217 A ES 409217A ES 409217 A1 ES409217 A1 ES 409217A1
Authority
ES
Spain
Prior art keywords
lower alkyl
formula
general formula
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES409217A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES409217A1 publication Critical patent/ES409217A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • C07D233/92Nitro radicals attached in position 4 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A procedure for the preparation of 5-nitroimidazole derivatives, of the general formula ** (See formula) ** in which R1 represents a lower alkyl, hydroxy- (lower alkyl) or (lower alkylcarbonyloxy) - (lower alkyl) group; R2 represents a hydrogen atom or a lower alkyl group and R3 a lower alkyl group or R2 and R3, together with the carbon atom to which they are attached, represent a hexagonal alicyclic ring, and its acid addition salts, characterized by reacting an amidoxime of the general formula and its acid addition salts, characterized by reacting an amidoxime of the general formula ** (See formula) ** R1 has the same meaning that has been attributed to it in formula I, with a carbonyl compound of the general formula ** (See formula) ** in which R2 and R3 have the same meaning as attributed to them in formula I, or with a respective acetal or ketal. (Machine-translation by Google Translate, not legally binding)
ES409217A 1971-12-03 1972-12-02 A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 5-NITROIMIDAZOLE. Expired ES409217A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1761271A CH563390A5 (en) 1971-12-03 1971-12-03

Publications (1)

Publication Number Publication Date
ES409217A1 true ES409217A1 (en) 1976-04-01

Family

ID=4426746

Family Applications (1)

Application Number Title Priority Date Filing Date
ES409217A Expired ES409217A1 (en) 1971-12-03 1972-12-02 A PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 5-NITROIMIDAZOLE.

Country Status (19)

Country Link
JP (1) JPS4864071A (en)
AR (1) AR197009A1 (en)
AT (1) AT318607B (en)
AU (1) AU468156B2 (en)
BE (1) BE792182A (en)
BR (1) BR7208497D0 (en)
CA (1) CA984395A (en)
CH (1) CH563390A5 (en)
DE (1) DE2252805A1 (en)
DK (1) DK132554C (en)
EG (1) EG10647A (en)
ES (1) ES409217A1 (en)
FR (1) FR2162176B1 (en)
GB (1) GB1358467A (en)
IL (1) IL40622A (en)
NL (1) NL7214493A (en)
PH (1) PH9530A (en)
SE (1) SE382987B (en)
ZA (1) ZA727455B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2506767A1 (en) * 1981-05-26 1982-12-03 Synthelabo HETEROCYCLIC DERIVATIVES OF AMIDOXIMES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70886A1 (en) * 1968-10-08 1970-01-20 Process for the preparation of 3- [4-Nitroimidazolyt- (5)] - 1,2,4-oxadiazoles
US3575998A (en) * 1969-09-16 1971-04-20 Merck & Co Inc Oxadiazolyl-substituted nitroimidazoles
US3658832A (en) * 1969-12-08 1972-04-25 American Cyanamid Co Novel antimicrobial nitroimidazolyl-1 2 4-oxadiazoles

Also Published As

Publication number Publication date
FR2162176B1 (en) 1975-08-08
AR197009A1 (en) 1974-03-08
NL7214493A (en) 1973-06-05
IL40622A (en) 1975-08-31
CH563390A5 (en) 1975-06-30
AT318607B (en) 1974-11-11
FR2162176A1 (en) 1973-07-13
BR7208497D0 (en) 1973-09-20
BE792182A (en) 1973-06-01
EG10647A (en) 1976-10-31
ZA727455B (en) 1973-07-25
IL40622A0 (en) 1972-12-29
AU4813772A (en) 1974-04-26
SE382987B (en) 1976-02-23
GB1358467A (en) 1974-07-03
AU468156B2 (en) 1976-01-08
DK132554B (en) 1975-12-29
PH9530A (en) 1976-01-09
JPS4864071A (en) 1973-09-05
CA984395A (en) 1976-02-24
DK132554C (en) 1976-05-31
DE2252805A1 (en) 1973-06-07

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