ES399188A1 - Procedimiento para la obtencion de derivados de la dibenzo (b,f) (1,4) oxazepina. - Google Patents
Procedimiento para la obtencion de derivados de la dibenzo (b,f) (1,4) oxazepina.Info
- Publication number
- ES399188A1 ES399188A1 ES399188A ES399188A ES399188A1 ES 399188 A1 ES399188 A1 ES 399188A1 ES 399188 A ES399188 A ES 399188A ES 399188 A ES399188 A ES 399188A ES 399188 A1 ES399188 A1 ES 399188A1
- Authority
- ES
- Spain
- Prior art keywords
- see formula
- formula
- compounds
- heating
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000000221 oxazepines Chemical class 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 alkyl nitrite Chemical compound 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- NPUACKRELIJTFM-UHFFFAOYSA-N cr gas Chemical class C1=NC2=CC=CC=C2OC2=CC=CC=C21 NPUACKRELIJTFM-UHFFFAOYSA-N 0.000 abstract 1
- 239000012954 diazonium Substances 0.000 abstract 1
- 150000001989 diazonium salts Chemical class 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/20—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8422170A | 1970-10-26 | 1970-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES399188A1 true ES399188A1 (es) | 1975-06-01 |
Family
ID=22183579
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES396390A Expired ES396390A1 (es) | 1970-10-26 | 1971-10-26 | Procedimiento para la obtencion de derivados de la dibenzo (b,f) (1,4) oxazepinas. |
| ES399188A Expired ES399188A1 (es) | 1970-10-26 | 1972-01-25 | Procedimiento para la obtencion de derivados de la dibenzo (b,f) (1,4) oxazepina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES396390A Expired ES396390A1 (es) | 1970-10-26 | 1971-10-26 | Procedimiento para la obtencion de derivados de la dibenzo (b,f) (1,4) oxazepinas. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3660406A (es) |
| AR (2) | AR192587A1 (es) |
| AT (2) | AT311983B (es) |
| BE (1) | BE774398A (es) |
| CA (1) | CA971169A (es) |
| CH (1) | CH576470A5 (es) |
| CS (1) | CS172359B2 (es) |
| DD (1) | DD97210A5 (es) |
| DE (1) | DE2153349A1 (es) |
| DK (1) | DK134066B (es) |
| ES (2) | ES396390A1 (es) |
| FR (1) | FR2111840B1 (es) |
| GB (1) | GB1340898A (es) |
| HK (1) | HK63276A (es) |
| IL (1) | IL37953A (es) |
| NL (1) | NL7114713A (es) |
| PL (1) | PL81422B1 (es) |
| SE (1) | SE380528B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI803030A7 (fi) * | 1979-10-01 | 1981-01-01 | Sandoz Ag | Dibentsatsepiinijohdannaiset, niiden tuotanto ja niitä sisältävät farmaseuttiset yhdistelmät. |
| US6423708B1 (en) * | 1996-09-30 | 2002-07-23 | Pfizer Inc | Aralkyl and aralkylidene heterocyclic lactams and imides |
| CN1741803A (zh) * | 2003-01-23 | 2006-03-01 | 阿卡蒂亚药品公司 | N－脱甲基氯氮平在治疗人神经精神疾病中的用途 |
| CA2550735A1 (en) * | 2003-12-22 | 2005-07-14 | Acadia Pharmaceuticals Inc. | Amino substituted diaryl[a,d]cycloheptene analogs as muscarinic agonists and methods of treatment of neuropsychiatric disorders |
| CN120981447A (zh) * | 2023-03-08 | 2025-11-18 | 法兰克福大学 | Slack激活化合物及其医学用途 |
| EP4428132A1 (en) * | 2023-03-08 | 2024-09-11 | Johann-Wolfgang-Goethe-Universität Frankfurt am Main | Slack-activating compounds and their medical use |
-
1970
- 1970-10-26 US US84221A patent/US3660406A/en not_active Expired - Lifetime
-
1971
- 1971-09-29 GB GB4542771A patent/GB1340898A/en not_active Expired
- 1971-10-17 IL IL37953A patent/IL37953A/xx unknown
- 1971-10-19 CA CA125,540A patent/CA971169A/en not_active Expired
- 1971-10-21 AR AR238595A patent/AR192587A1/es active
- 1971-10-25 PL PL1971151205A patent/PL81422B1/pl unknown
- 1971-10-25 DK DK517771AA patent/DK134066B/da unknown
- 1971-10-25 AT AT1056772A patent/AT311983B/de active
- 1971-10-25 AT AT921871A patent/AT311979B/de active
- 1971-10-25 SE SE7113522A patent/SE380528B/xx unknown
- 1971-10-25 BE BE774398A patent/BE774398A/xx unknown
- 1971-10-26 CS CS7545A patent/CS172359B2/cs unknown
- 1971-10-26 FR FR7138476A patent/FR2111840B1/fr not_active Expired
- 1971-10-26 ES ES396390A patent/ES396390A1/es not_active Expired
- 1971-10-26 DE DE2153349A patent/DE2153349A1/de active Pending
- 1971-10-26 DD DD158567A patent/DD97210A5/xx unknown
- 1971-10-26 NL NL7114713A patent/NL7114713A/xx unknown
- 1971-10-26 CH CH1557371A patent/CH576470A5/xx not_active IP Right Cessation
-
1972
- 1972-01-25 ES ES399188A patent/ES399188A1/es not_active Expired
- 1972-06-22 AR AR242690A patent/AR192798A1/es active
-
1976
- 1976-10-07 HK HK632/76*UA patent/HK63276A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK63276A (en) | 1976-10-15 |
| AR192587A1 (es) | 1973-02-28 |
| AT311979B (de) | 1973-12-10 |
| IL37953A0 (en) | 1971-12-29 |
| AU3400171A (en) | 1973-04-05 |
| AT311983B (de) | 1973-12-10 |
| SU437301A3 (ru) | 1974-07-25 |
| FR2111840B1 (es) | 1975-08-01 |
| US3660406A (en) | 1972-05-02 |
| GB1340898A (en) | 1973-12-19 |
| SE380528B (sv) | 1975-11-10 |
| FR2111840A1 (es) | 1972-06-09 |
| IL37953A (en) | 1975-07-28 |
| CA971169A (en) | 1975-07-15 |
| BE774398A (fr) | 1972-04-25 |
| DD97210A5 (es) | 1973-04-20 |
| DE2153349A1 (de) | 1972-04-27 |
| PL81422B1 (en) | 1975-08-30 |
| NL7114713A (es) | 1972-04-28 |
| DK134066C (es) | 1977-02-07 |
| CH576470A5 (es) | 1976-06-15 |
| ES396390A1 (es) | 1975-01-01 |
| DK134066B (da) | 1976-09-06 |
| AR192798A1 (es) | 1973-03-14 |
| CS172359B2 (es) | 1976-12-29 |
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