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ES301833A1 - Un procedimiento para la prepación de 19-alkil-esteroides - Google Patents

Un procedimiento para la prepación de 19-alkil-esteroides

Info

Publication number
ES301833A1
ES301833A1 ES301833A ES301833A ES301833A1 ES 301833 A1 ES301833 A1 ES 301833A1 ES 301833 A ES301833 A ES 301833A ES 301833 A ES301833 A ES 301833A ES 301833 A1 ES301833 A1 ES 301833A1
Authority
ES
Spain
Prior art keywords
formula
steroid
compound
alkyl
partial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES301833A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of ES301833A1 publication Critical patent/ES301833A1/es
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
ES301833A 1963-07-09 1964-07-08 Un procedimiento para la prepación de 19-alkil-esteroides Expired ES301833A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH851363A CH433275A (de) 1963-07-09 1963-07-09 Verfahren zur Herstellung von 19-Alkylsteroiden

Publications (1)

Publication Number Publication Date
ES301833A1 true ES301833A1 (es) 1962-12-16

Family

ID=4341402

Family Applications (1)

Application Number Title Priority Date Filing Date
ES301833A Expired ES301833A1 (es) 1963-07-09 1964-07-08 Un procedimiento para la prepación de 19-alkil-esteroides

Country Status (10)

Country Link
US (1) US3309387A (es)
BE (1) BE650260A (es)
BR (1) BR6460648D0 (es)
CH (1) CH433275A (es)
DE (1) DE1468035C3 (es)
DK (1) DK115400B (es)
ES (1) ES301833A1 (es)
GB (1) GB1040554A (es)
NL (1) NL6406879A (es)
SE (1) SE312554B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH464189A (de) * 1966-04-20 1968-10-31 Hoffmann La Roche Verfahren zur Herstellung von 19-Alkenylsteroiden
US3859272A (en) * 1968-07-23 1975-01-07 Hoechst Ag 19-alkylene-14- ' -hydroxy-cardenolide derivatives and process for preparing them
US4139617A (en) * 1974-05-13 1979-02-13 Richardson-Merrell Inc. 19-Oxygenated-androst-5-enes for the enhancement of libido
WO2005020928A2 (en) * 2003-08-29 2005-03-10 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
CN1882606A (zh) * 2003-11-24 2006-12-20 默克公司 雌激素受体调节剂
CN1968960A (zh) * 2004-06-10 2007-05-23 默克公司 雌激素受体调节剂
AU2005267210A1 (en) * 2004-06-30 2006-02-02 Merck & Co., Inc. Estrogen receptor modulators
US9670244B2 (en) * 2006-02-27 2017-06-06 The Regents Of The University Of California Oxysterol compounds and the hedgehog pathway
JP2011505357A (ja) * 2007-12-03 2011-02-24 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア ヘッジホッグシグナル伝達、骨誘導、抗脂肪生成、及びｗｎｔシグナル伝達を活性するためのオキシステロール
EP2847206A4 (en) 2012-05-07 2016-01-20 Univ California OXYSTEROL ANALOGUE OXY133 FOR INDUCTION OF OSTEOGENESIS AND HEDGEHOG SIGNALING AND ADIPOGENESIS INHIBITION
EP2991652A4 (en) 2013-05-02 2016-12-07 Univ California BONE-LAYERED BONE-RELATED OSTEOGENIC OXYSTEROL AGENTS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2844603A (en) * 1955-07-05 1958-07-22 Searle & Co Process for oxidation of steroids with peroxytrifluoroacetic acid
NL286295A (es) * 1961-12-04
NL292848A (es) * 1962-05-16
US3206458A (en) * 1962-06-12 1965-09-14 Syntex Corp 19-substituted pregnenes
US3102127A (en) * 1962-06-12 1963-08-27 Syntex Corp 19-methylene-androstane derivatives

Also Published As

Publication number Publication date
DE1468035A1 (de) 1968-12-12
BE650260A (es) 1965-01-08
DK115400B (da) 1969-10-06
GB1040554A (en) 1966-09-01
DE1468035C3 (de) 1974-03-21
CH433275A (de) 1967-04-15
DE1468035B2 (de) 1973-08-02
SE312554B (es) 1969-07-21
US3309387A (en) 1967-03-14
BR6460648D0 (pt) 1973-12-26
NL6406879A (es) 1965-01-11

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