ES289641A1 - Procedimiento para preparar nuevos compuestos de la 6-metil y la 1,6-dimetil-ergolina ii - Google Patents
Procedimiento para preparar nuevos compuestos de la 6-metil y la 1,6-dimetil-ergolina iiInfo
- Publication number
- ES289641A1 ES289641A1 ES0289641A ES289641A ES289641A1 ES 289641 A1 ES289641 A1 ES 289641A1 ES 0289641 A ES0289641 A ES 0289641A ES 289641 A ES289641 A ES 289641A ES 289641 A1 ES289641 A1 ES 289641A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- acid
- dihydrolysergol
- general formula
- ergoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical compound O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- -1 acyl radical Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 230000002196 ecbolic effect Effects 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- SIOXPEMLGUPBBT-UHFFFAOYSA-N picolinic acid Chemical compound OC(=O)C1=CC=CC=N1 SIOXPEMLGUPBBT-UHFFFAOYSA-N 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1341062 | 1962-07-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES289641A1 true ES289641A1 (es) | 1963-10-16 |
Family
ID=11144424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0289641A Expired ES289641A1 (es) | 1962-07-05 | 1963-07-04 | Procedimiento para preparar nuevos compuestos de la 6-metil y la 1,6-dimetil-ergolina ii |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE634493A (es) |
| ES (1) | ES289641A1 (es) |
| GB (1) | GB1047164A (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1048122B (it) * | 1973-05-23 | 1980-11-20 | Simes | Carbammati di ergoline |
-
1963
- 1963-07-01 GB GB26066/63A patent/GB1047164A/en not_active Expired
- 1963-07-04 ES ES0289641A patent/ES289641A1/es not_active Expired
- 1963-07-04 BE BE634493A patent/BE634493A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE634493A (fr) | 1963-11-18 |
| GB1047164A (en) | 1966-11-02 |
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