ES2141463T3 - Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans. - Google Patents
Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans.Info
- Publication number
- ES2141463T3 ES2141463T3 ES96830093T ES96830093T ES2141463T3 ES 2141463 T3 ES2141463 T3 ES 2141463T3 ES 96830093 T ES96830093 T ES 96830093T ES 96830093 T ES96830093 T ES 96830093T ES 2141463 T3 ES2141463 T3 ES 2141463T3
- Authority
- ES
- Spain
- Prior art keywords
- carnitine
- treatment
- derivative
- arteriosclerosis obliterans
- medication containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
SE MUESTRA EL USO DE UN PROPIONIL L-CARNITINA Y SALES ACEPTABLES FARMACOLOGICAMENTE DE LA MISMA PARA ELABORAR UN MEDICAMENTO PARA TRATAR LAS REMISIONES DE LA ARTERIOESCLEROSIS CRONICA QUE ESTA INDICADO SELECTIVAMENTE PARA EL TRATAMIENTO DE PACIENTES CON REMISION INTERMITENTE INCAPACITANTE SEVERA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96830093A EP0793962B1 (en) | 1996-03-04 | 1996-03-04 | Medicament containing a carnitine derivative for treating arteriosclerosis obliterans |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2141463T3 true ES2141463T3 (es) | 2000-03-16 |
Family
ID=8225823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES96830093T Expired - Lifetime ES2141463T3 (es) | 1996-03-04 | 1996-03-04 | Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5811457A (es) |
| EP (1) | EP0793962B1 (es) |
| JP (1) | JPH09323927A (es) |
| KR (1) | KR100346883B1 (es) |
| AT (1) | ATE187329T1 (es) |
| CA (1) | CA2198833C (es) |
| DE (1) | DE69605531T2 (es) |
| DK (1) | DK0793962T3 (es) |
| ES (1) | ES2141463T3 (es) |
| GR (1) | GR3032903T3 (es) |
| PT (1) | PT793962E (es) |
| TW (1) | TW349863B (es) |
| ZA (1) | ZA971808B (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
| IT1295408B1 (it) * | 1997-10-03 | 1999-05-12 | Sigma Tau Ind Farmaceuti | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
| AU1258699A (en) * | 1998-11-11 | 2000-05-29 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of propionylcarnitine for the manufacture of a medicament for inhibiting smooth muscle cell proliferation |
| EP1128823A1 (en) * | 1998-11-11 | 2001-09-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Use of propionyl l-carnitine for the preparation of a medicament capable of inducing apoptosis |
| IT1316998B1 (it) * | 2000-03-02 | 2003-05-26 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento degli effetticitotossici indotti dall'uso di agenti immunosoppressori. |
| ITRM20010708A1 (it) * | 2001-12-04 | 2003-06-04 | Sigma Tau Ind Farmaceuti | Uso di una alcanoil l-carnitina per il trattamento della disfunzione erettile. |
| KR20040101521A (ko) * | 2002-04-18 | 2004-12-02 | 추가이 세이야쿠 가부시키가이샤 | 혈관 내피의 혈관 장력 조절 기능을 개선하기 위한 의약조성물 |
| US7776913B2 (en) * | 2002-12-13 | 2010-08-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Carnitines for treating or preventing disorders caused by andropause |
| US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
| WO2006061341A1 (en) * | 2004-12-10 | 2006-06-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of propionyl l-carnitine for the preparation of a high-dose medicament for the treatment of peripheral arterial disease |
| US7560485B2 (en) * | 2005-10-04 | 2009-07-14 | Sigma-Tau Industrie Parmaceutiche Riunite S.P.A. | Method for treating intermittent claudication comprising the administration of propionyl L-carnitine and a concomitant physical training |
| EP2353596A1 (en) | 2010-02-02 | 2011-08-10 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency |
| KR20130089158A (ko) | 2010-06-16 | 2013-08-09 | 시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이. | 신경 조직에서 신경발생을 증가시키기 위한 방법에 사용하기 위한 아세틸-카르니틴 |
| WO2012069221A1 (en) | 2010-11-22 | 2012-05-31 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutical method for the treatment of the leber optic |
| EP2648717A1 (en) | 2010-12-09 | 2013-10-16 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Composition for topical use for treating skin disorders |
| EP2783695A1 (en) | 2013-03-28 | 2014-10-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1206954B (it) * | 1979-02-12 | 1989-05-17 | Sigma Tau Ind Farmaceuti | Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche |
| IT1142934B (it) * | 1981-11-06 | 1986-10-15 | Sigma Tau Ind Farmaceuti | Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene |
| US4968719A (en) * | 1989-04-03 | 1990-11-06 | Sigma Tau, Industrie Farmaceutiche Riunite Spa | Method for treating vascular disease |
-
1996
- 1996-03-04 PT PT96830093T patent/PT793962E/pt unknown
- 1996-03-04 DK DK96830093T patent/DK0793962T3/da active
- 1996-03-04 EP EP96830093A patent/EP0793962B1/en not_active Expired - Lifetime
- 1996-03-04 DE DE69605531T patent/DE69605531T2/de not_active Expired - Lifetime
- 1996-03-04 ES ES96830093T patent/ES2141463T3/es not_active Expired - Lifetime
- 1996-03-04 AT AT96830093T patent/ATE187329T1/de active
- 1996-09-16 US US08/714,424 patent/US5811457A/en not_active Expired - Lifetime
-
1997
- 1997-01-28 TW TW086100923A patent/TW349863B/zh not_active IP Right Cessation
- 1997-02-12 KR KR1019970004057A patent/KR100346883B1/ko not_active Expired - Fee Related
- 1997-02-28 CA CA002198833A patent/CA2198833C/en not_active Expired - Fee Related
- 1997-03-03 ZA ZA971808A patent/ZA971808B/xx unknown
- 1997-03-04 JP JP9048765A patent/JPH09323927A/ja active Pending
-
2000
- 2000-03-08 GR GR20000400598T patent/GR3032903T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9701294A (es) | 1997-09-30 |
| JPH09323927A (ja) | 1997-12-16 |
| DK0793962T3 (da) | 2000-05-22 |
| KR100346883B1 (ko) | 2003-01-06 |
| TW349863B (en) | 1999-01-11 |
| ATE187329T1 (de) | 1999-12-15 |
| CA2198833C (en) | 2003-07-22 |
| EP0793962A1 (en) | 1997-09-10 |
| EP0793962B1 (en) | 1999-12-08 |
| US5811457A (en) | 1998-09-22 |
| ZA971808B (en) | 1998-07-31 |
| DE69605531D1 (de) | 2000-01-13 |
| CA2198833A1 (en) | 1997-09-04 |
| PT793962E (pt) | 2000-05-31 |
| KR970064602A (ko) | 1997-10-13 |
| DE69605531T2 (de) | 2000-05-31 |
| GR3032903T3 (en) | 2000-07-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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