ES2067395B1 - Derivados de nucleosidos o analogos a nucleosidos. - Google Patents
Derivados de nucleosidos o analogos a nucleosidos.Info
- Publication number
- ES2067395B1 ES2067395B1 ES9300478A ES9300478A ES2067395B1 ES 2067395 B1 ES2067395 B1 ES 2067395B1 ES 9300478 A ES9300478 A ES 9300478A ES 9300478 A ES9300478 A ES 9300478A ES 2067395 B1 ES2067395 B1 ES 2067395B1
- Authority
- ES
- Spain
- Prior art keywords
- nucleoside
- nucleosides
- derivatives
- analogs
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002777 nucleoside Substances 0.000 title abstract 7
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 abstract 2
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- GFFGJBXGBJISGV-RVQWGROCSA-N 2,8-ditritio-7h-purin-6-amine Chemical compound [3H]C1=NC(N)=C2NC([3H])=NC2=N1 GFFGJBXGBJISGV-RVQWGROCSA-N 0.000 abstract 1
- -1 HYDROXYL GROUP Chemical group 0.000 abstract 1
- RWQNBRDOKXIBIV-CNRUNOGKSA-N [3H]Cc1c[nH]c(=O)[nH]c1=O Chemical compound [3H]Cc1c[nH]c(=O)[nH]c1=O RWQNBRDOKXIBIV-CNRUNOGKSA-N 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940104302 cytosine Drugs 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
DERIVADOS DE NUCLEOSIDOS O ANALOGOS A NUCLEOSIDOS QUE COMPRENDEN UNA BASE NITROGENADA SELECCIONADA ENTRE ADENINA, GUANINA, CITOSINA, URACILO Y TIMINA, Y QUE TIENEN LA FORMULA GENERAL I: NU-O-FA EN LA QUE O REPRESENTA UN ATOMO DE OXIGENO, NU ES UN NUCLEOSIDO O ANALOGO A NUCLEOSIDO Y FA ES UN GRUPO ACILO DE UN ACIDO GRASO C18 A C20 MONO-INSATURADO, ESTERIFICADO CON UN GRUPO HIDROXILO EN LA POSICION 5" DEL RESTO AZUCAR DEL NUCLEOSIDO O CON UN GRUPO HIDROXILO DE LA CADENA NO CICLICA DEL ANALOGO A NUCLEOSIDO. TAMBIEN SE DESCRIBEN COMPOSICIONES ANTI-VIRICAS FARMACEUTICAS Y VETERINARIAS QUE COMPRENDEN UN COMPUESTO DE LA FORMULA I SOLO O EN COMBINACION CON UN VEHICULO FARMACEUTICAMENTE ACEPTABLE. ESTOS DERIVADOS Y COMPOSICIONES SON UTILES PARA TRATAR UN PACIENTE HUMANO O ANIMAL QUE SUFRA UNA INFECCION VIRICA Y PARA REDUCIR LA CARGA INFECCIOSA.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9300478A ES2067395B1 (es) | 1993-03-10 | 1993-03-10 | Derivados de nucleosidos o analogos a nucleosidos. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9300478A ES2067395B1 (es) | 1993-03-10 | 1993-03-10 | Derivados de nucleosidos o analogos a nucleosidos. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2067395A1 ES2067395A1 (es) | 1995-03-16 |
| ES2067395B1 true ES2067395B1 (es) | 1996-01-01 |
Family
ID=8281044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9300478A Expired - Fee Related ES2067395B1 (es) | 1993-03-10 | 1993-03-10 | Derivados de nucleosidos o analogos a nucleosidos. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES2067395B1 (es) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3100478A1 (de) * | 1981-01-09 | 1982-08-12 | Dr. Thilo & Co GmbH, 8021 Sauerlach | 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel |
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| WO1988007532A1 (en) * | 1987-03-24 | 1988-10-06 | Nycomed A.S. | 2',3' dideoxyribofuranoxide derivatives |
-
1993
- 1993-03-10 ES ES9300478A patent/ES2067395B1/es not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2067395A1 (es) | 1995-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20141120 |