EE9700310A - N-propargüül-1-aminoindaani R-enantiomeeri, selle soolade ja kompositsioonide kasutamine - Google Patents

N-propargüül-1-aminoindaani R-enantiomeeri, selle soolade ja kompositsioonide kasutamine

Info

Publication number: EE9700310A
Authority: EE; Estonia
Prior art keywords: aminoindan; propargyl; enantiomer; salts; compositions
Prior art date: 1995-05-22

Application number

EE9700310A

Other languages

English (en)

Other versions

EE03741B1 (et

Inventor

B. H. Youdim Moussa

P. M. Finberg John

Levy Ruth

Sterling Jeffrey

Lerner David

Yellin Haim

Veinberg Alex

Original Assignee

Teva Pharmaceutical Industries, Ltd.

Technion Research And Development Foundation Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-22

Filing date

1996-05-22

Publication date

1998-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23772591&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE9700310(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-05-22 Application filed by Teva Pharmaceutical Industries, Ltd., Technion Research And Development Foundation Ltd. filed Critical Teva Pharmaceutical Industries, Ltd.

1998-06-15 Publication of EE9700310A publication Critical patent/EE9700310A/et

2002-06-17 Publication of EE03741B1 publication Critical patent/EE03741B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
- C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
- C07C211/42—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Emergency Medicine (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)

EE9700310A 1995-05-22 1996-05-22 N-propargüül-1-aminoindaani R-enantiomeeri, sellesoolade ja kompositsioonide kasutamine EE03741B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/446,439 US5744500A (en)	1990-01-03	1995-05-22	Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof
PCT/US1996/007465 WO1996037199A1 (en)	1995-05-22	1996-05-22	Use of r-enantiomer of n-propargyl-1-aminoindan, salts, and compositions thereof

Publications (2)

Publication Number	Publication Date
EE9700310A true EE9700310A (et)	1998-06-15
EE03741B1 EE03741B1 (et)	2002-06-17

Family

ID=23772591

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9700310A EE03741B1 (et)	1995-05-22	1996-05-22	N-propargüül-1-aminoindaani R-enantiomeeri, sellesoolade ja kompositsioonide kasutamine

Country Status (21)

Country	Link
US (6)	US5744500A (et)
EP (1)	EP0828485A4 (et)
JP (1)	JP3341898B2 (et)
KR (1)	KR100412154B1 (et)
CN (1)	CN1096853C (et)
AU (1)	AU699090B2 (et)
BR (1)	BR9608733A (et)
CA (1)	CA2221458A1 (et)
CZ (1)	CZ288724B6 (et)
EE (1)	EE03741B1 (et)
HU (1)	HUP9901629A3 (et)
IL (1)	IL118247A (et)
LT (1)	LT4455B (et)
LV (1)	LV12083B (et)
MX (1)	MX9708977A (et)
NO (1)	NO975331L (et)
NZ (1)	NZ308866A (et)
PL (1)	PL184124B1 (et)
RU (1)	RU2203653C2 (et)
SK (1)	SK283675B6 (et)
WO (1)	WO1996037199A1 (et)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
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1995
- 1995-05-22 US US08/446,439 patent/US5744500A/en not_active Expired - Lifetime
1996
- 1996-05-14 IL IL11824796A patent/IL118247A/en not_active IP Right Cessation
- 1996-05-22 PL PL96323470A patent/PL184124B1/pl not_active IP Right Cessation
- 1996-05-22 CA CA002221458A patent/CA2221458A1/en not_active Abandoned
- 1996-05-22 EP EP96920401A patent/EP0828485A4/en not_active Ceased
- 1996-05-22 SK SK1574-97A patent/SK283675B6/sk unknown
- 1996-05-22 RU RU97121002/14A patent/RU2203653C2/ru not_active IP Right Cessation
- 1996-05-22 NZ NZ308866A patent/NZ308866A/en not_active IP Right Cessation
- 1996-05-22 HU HU9901629A patent/HUP9901629A3/hu unknown
- 1996-05-22 EE EE9700310A patent/EE03741B1/et not_active IP Right Cessation
- 1996-05-22 KR KR1019970708371A patent/KR100412154B1/ko not_active Expired - Fee Related
- 1996-05-22 US US08/952,705 patent/US6316504B1/en not_active Expired - Lifetime
- 1996-05-22 WO PCT/US1996/007465 patent/WO1996037199A1/en not_active Ceased
- 1996-05-22 AU AU58723/96A patent/AU699090B2/en not_active Expired
- 1996-05-22 CZ CZ19973699A patent/CZ288724B6/cs not_active IP Right Cessation
- 1996-05-22 JP JP53584496A patent/JP3341898B2/ja not_active Expired - Fee Related
- 1996-05-22 CN CN96195710A patent/CN1096853C/zh not_active Expired - Fee Related
- 1996-05-22 BR BR9608733-1A patent/BR9608733A/pt not_active Application Discontinuation
- 1996-05-22 MX MX9708977A patent/MX9708977A/es unknown
1997
- 1997-11-20 NO NO975331A patent/NO975331L/no not_active Application Discontinuation
- 1997-12-22 LT LT97-200A patent/LT4455B/lt not_active IP Right Cessation
1998
- 1998-01-20 LV LVP-97-267A patent/LV12083B/en unknown
2001
- 2001-10-26 US US10/016,268 patent/US6630514B2/en not_active Expired - Fee Related
2002
- 2002-11-27 US US10/305,478 patent/US6956060B2/en not_active Expired - Fee Related
2005
- 2005-06-17 US US11/155,864 patent/US20060094783A1/en not_active Abandoned
2006
- 2006-11-10 US US11/595,726 patent/US20070100001A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2000508292A (ja)	2000-07-04
PL184124B1 (pl)	2002-09-30
HUP9901629A2 (hu)	2000-02-28
EE03741B1 (et)	2002-06-17
CZ288724B6 (cs)	2001-08-15
US6956060B2 (en)	2005-10-18
HK1015269A1 (en)	1999-10-15
US20060094783A1 (en)	2006-05-04
JP3341898B2 (ja)	2002-11-05
US5744500A (en)	1998-04-28
LV12083A (lv)	1998-07-20
SK157497A3 (en)	1998-05-06
KR19990021896A (ko)	1999-03-25
US20030212145A1 (en)	2003-11-13
SK283675B6 (sk)	2003-11-04
US6630514B2 (en)	2003-10-07
WO1996037199A8 (en)	1999-08-12
EP0828485A1 (en)	1998-03-18
US20070100001A1 (en)	2007-05-03
WO1996037199A1 (en)	1996-11-28
KR100412154B1 (ko)	2004-07-05
PL323470A1 (en)	1998-03-30
AU699090B2 (en)	1998-11-19
CZ369997A3 (cs)	1999-06-16
NZ308866A (en)	1999-09-29
NO975331L (no)	1998-01-20
CN1096853C (zh)	2002-12-25
EP0828485A4 (en)	1998-12-02
AU5872396A (en)	1996-12-11
RU2203653C2 (ru)	2003-05-10
CA2221458A1 (en)	1996-11-28
LT4455B (lt)	1999-01-25
LV12083B (en)	1998-09-20
LT97200A (en)	1998-09-25
MX9708977A (es)	1998-03-31
US6316504B1 (en)	2001-11-13
US20030065038A1 (en)	2003-04-03
IL118247A (en)	2002-07-25
NO975331D0 (no)	1997-11-20
IL118247A0 (en)	1996-09-12
BR9608733A (pt)	1999-12-07
CN1191481A (zh)	1998-08-26
HUP9901629A3 (en)	2000-03-28

Publication	Publication Date	Title
EE9700310A (et)	1998-06-15	N-propargüül-1-aminoindaani R-enantiomeeri, selle soolade ja kompositsioonide kasutamine
FI955235A7 (fi)	1996-05-03	Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
FI940904A7 (fi)	1994-11-29	Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI941378L (fi)	1994-09-25	Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
EE200200341A (et)	2003-10-15	Asendatud oksasolidinoonid ja nende kasutamine
FI962494L (fi)	1996-06-14	5-(2-imidatsolinyyliamino)bentsimidatsolijohdannaisia, niiden valmistus ja niiden käyttö alpha-2-adrenoseptoriagonisteina
FI945281A7 (fi)	1995-05-11	Heterosykliset yhdisteet, niiden valmistus ja käyttö
FI963183A7 (fi)	1996-10-16	Vesipitoinen dispersiokoostumus, ja sitä käyttävä koostumus
BR9508677A (pt)	1997-12-23	Copolímero prodesso de preparação do mesmo e composição orgânica
FI972629A7 (fi)	1997-06-18	Aryyli- ja heteroaryylisulfonamidijohdoksia, niiden valmistus ja niiden käyttö endoteliinin antagonisteina
DK0736525T3 (da)	2000-10-30	Benzonitriler som 5-HT-agonister og -antagonister
EE200000621A (et)	2002-06-17	Pikornaviirusevastased ühendid, nende valmistamine ja kasutamine
FI962043L (fi)	1996-05-14	Substituoidut 5-rengas-heterosyklit, niiden valmistus ja niiden käyttö
FI970094A7 (fi)	1997-01-10	Substituoidut bentsamidiinit, niiden valmistus ja käyttö lääkeaineena
FI990134L (fi)	1999-03-24	Pyridatsino-(4,5-beta)-kinoliini-5-oksidijohdannaisia, niiden valmistus ja niiden käyttö glysiiniantagonisteina
FI944417A7 (fi)	1995-03-25	Atsoliyhdisteet, niiden valmistus ja käyttö
EE9900524A (et)	2000-06-15	N-triasolüül-2-indoolkarboksamiidid ja nende kasutamine CCK-A agonistidena
EE200100347A (et)	2002-12-16	3,3-biarüülpiperidiini ja 2,2-biarüülmorfoliini derivaadid
FI964031L (fi)	1996-10-08	Bentsamidijohdannainen, mainittua johdannaista sisältävät koostumukset ja sen käyttö
FI970997L (fi)	1997-03-10	Bentsosykloalkeeniyhdisteet, niiden valmistus ja käyttö
FI972306A0 (fi)	1997-05-30	Substituoituja 2-aryylikarbonyylioksimetyyli-1,2,5-tiadiatsolidin -3- oni-1,1-dioksidi-johdannaisia ja niitä sisältäviä koostumuksia ja menetelmiä niiden käyttämiseksi
FI954229L (fi)	1995-09-08	Heterosykliset yhdisteet, niiden käyttö ja valmistus
FI944040A7 (fi)	1995-03-04	Laktolijohdannaiset, niiden valmistus ja käyttö
EE9900311A (et)	2000-02-15	Söödalisandi valmistamise meetod, söödalisand ja selle kasutamine
FI970750L (fi)	1997-03-13	Indoli-2,3-dioni-3-oksimijohdannaisia, niiden valmistus ja käyttö

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