EE200300586A - Adenosiini A2A retseptori agonisti ja antikolinergilise vahendi kombinatsioon obstruktiivsete hingamisteede haiguste raviks - Google Patents
Adenosiini A2A retseptori agonisti ja antikolinergilise vahendi kombinatsioon obstruktiivsete hingamisteede haiguste raviksInfo
- Publication number
- EE200300586A EE200300586A EEP200300586A EEP200300586A EE200300586A EE 200300586 A EE200300586 A EE 200300586A EE P200300586 A EEP200300586 A EE P200300586A EE P200300586 A EEP200300586 A EE P200300586A EE 200300586 A EE200300586 A EE 200300586A
- Authority
- EE
- Estonia
- Prior art keywords
- adenosine
- treatment
- combination
- receptor agonist
- anticholinergic agent
- Prior art date
Links
- 229940122086 Adenosine A2a receptor agonist Drugs 0.000 title 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title 1
- 208000027771 Obstructive airways disease Diseases 0.000 title 1
- 239000002465 adenosine A2a receptor agonist Substances 0.000 title 1
- 239000000812 cholinergic antagonist Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29384201P | 2001-05-25 | 2001-05-25 | |
| GB0129275A GB0129275D0 (en) | 2001-12-06 | 2001-12-06 | Pharmaceutical combination |
| GB0210238A GB0210238D0 (en) | 2002-05-03 | 2002-05-03 | Pharmaceutical composition |
| PCT/EP2002/005725 WO2002096462A1 (en) | 2001-05-25 | 2002-05-24 | An adenosine a2a receptor agonist and an anticholinergic agent in combination for treating obstructive airways diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200300586A true EE200300586A (et) | 2004-04-15 |
Family
ID=27256345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300586A EE200300586A (et) | 2001-05-25 | 2002-05-24 | Adenosiini A2A retseptori agonisti ja antikolinergilise vahendi kombinatsioon obstruktiivsete hingamisteede haiguste raviks |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20040171576A1 (et) |
| EP (1) | EP1395287A1 (et) |
| KR (1) | KR20030097901A (et) |
| CN (1) | CN1535161A (et) |
| AP (1) | AP2003002911A0 (et) |
| BG (1) | BG108383A (et) |
| BR (1) | BR0209986A (et) |
| CA (1) | CA2448086A1 (et) |
| CO (1) | CO5540324A2 (et) |
| CZ (1) | CZ20033126A3 (et) |
| EE (1) | EE200300586A (et) |
| HU (1) | HUP0400029A2 (et) |
| IL (1) | IL158774A0 (et) |
| MA (1) | MA27028A1 (et) |
| MX (1) | MXPA03010787A (et) |
| NO (1) | NO20035202D0 (et) |
| OA (1) | OA12609A (et) |
| PA (1) | PA8546101A1 (et) |
| PL (1) | PL366899A1 (et) |
| SK (1) | SK14302003A3 (et) |
| SV (1) | SV2003001055A (et) |
| WO (1) | WO2002096462A1 (et) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7378400B2 (en) | 1999-02-01 | 2008-05-27 | University Of Virginia Patent Foundation | Method to reduce an inflammatory response from arthritis |
| US6232297B1 (en) | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
| US7427606B2 (en) * | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
| AU2002362443B2 (en) | 2001-10-01 | 2008-05-15 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs having A2A agonist activity and compositions thereof |
| GB0129273D0 (en) * | 2001-12-06 | 2002-01-23 | Pfizer Ltd | Crystalline drug form |
| AR044519A1 (es) | 2003-05-02 | 2005-09-14 | Novartis Ag | Derivados de piridin-tiazol amina y de pirimidin-tiazol amina |
| GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| AR049384A1 (es) * | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
| WO2006023272A1 (en) | 2004-08-02 | 2006-03-02 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having a2a agonist activity |
| WO2006028618A1 (en) | 2004-08-02 | 2006-03-16 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity |
| EP1778712B1 (en) | 2004-08-02 | 2013-01-30 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity |
| GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
| GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| GB0511065D0 (en) * | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| EP2532678A1 (en) | 2005-10-21 | 2012-12-12 | Novartis AG | Human antibodies against il13 and therapeutic uses |
| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| JP2010504933A (ja) | 2006-09-29 | 2010-02-18 | ノバルティス アーゲー | Pi3k脂質キナーゼ阻害剤としてのピラゾロピリミジン |
| BRPI0718266A2 (pt) | 2006-10-30 | 2014-01-07 | Novartis Ag | Compostos heterocíclicos como agentes anti-inflamatórios. |
| PT2231642E (pt) | 2008-01-11 | 2014-03-12 | Novartis Ag | Pirimidinas como inibidores de quinase |
| WO2010088335A1 (en) | 2009-01-29 | 2010-08-05 | Novartis Ag | Substituted benzimidazoles for the treatment of astrocytomas |
| US8389526B2 (en) | 2009-08-07 | 2013-03-05 | Novartis Ag | 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives |
| KR20120089643A (ko) | 2009-08-12 | 2012-08-13 | 노파르티스 아게 | 헤테로시클릭 히드라존 화합물, 및 암 및 염증을 치료하기 위한 그의 용도 |
| PE20170003A1 (es) | 2009-08-17 | 2017-03-15 | Intellikine Llc | Compuestos heterociclicos y usos de los mismos |
| IN2012DN01453A (et) | 2009-08-20 | 2015-06-05 | Novartis Ag | |
| WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
| US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
| EP2673277A1 (en) | 2011-02-10 | 2013-12-18 | Novartis AG | [1, 2, 4]triazolo [4, 3 -b]pyridazine compounds as inhibitors of the c-met tyrosine kinase |
| WO2012116237A2 (en) | 2011-02-23 | 2012-08-30 | Intellikine, Llc | Heterocyclic compounds and uses thereof |
| EA201391230A1 (ru) | 2011-02-25 | 2014-01-30 | АйАрЭм ЭлЭлСи | Соединения и композиции в качестве ингибиторов trk |
| UY34329A (es) | 2011-09-15 | 2013-04-30 | Novartis Ag | Compuestos de triazolopiridina |
| WO2013078440A2 (en) | 2011-11-23 | 2013-05-30 | Intellikine, Llc | Enhanced treatment regimens using mtor inhibitors |
| WO2013149581A1 (en) | 2012-04-03 | 2013-10-10 | Novartis Ag | Combination products with tyrosine kinase inhibitors and their use |
| WO2014151147A1 (en) | 2013-03-15 | 2014-09-25 | Intellikine, Llc | Combination of kinase inhibitors and uses thereof |
| TW201605450A (zh) | 2013-12-03 | 2016-02-16 | 諾華公司 | Mdm2抑制劑與BRAF抑制劑之組合及其用途 |
| WO2016011658A1 (en) | 2014-07-25 | 2016-01-28 | Novartis Ag | Combination therapy |
| EP3174869B1 (en) | 2014-07-31 | 2020-08-19 | Novartis AG | Combination therapy of a met inhibitor and an egfr inhibitor |
| TW202140550A (zh) | 2020-01-29 | 2021-11-01 | 瑞士商諾華公司 | 使用抗tslp抗體治療炎性或阻塞性氣道疾病之方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant |
| ATE331726T1 (de) * | 1998-10-16 | 2006-07-15 | Pfizer | Adenine-derivate |
| GB9924363D0 (en) * | 1999-10-14 | 1999-12-15 | Pfizer Central Res | Purine derivatives |
-
2002
- 2002-05-24 BR BR0209986-1A patent/BR0209986A/pt not_active IP Right Cessation
- 2002-05-24 EP EP02745316A patent/EP1395287A1/en not_active Withdrawn
- 2002-05-24 SK SK1430-2003A patent/SK14302003A3/sk not_active Application Discontinuation
- 2002-05-24 WO PCT/EP2002/005725 patent/WO2002096462A1/en not_active Ceased
- 2002-05-24 CA CA002448086A patent/CA2448086A1/en not_active Abandoned
- 2002-05-24 OA OA1200300303A patent/OA12609A/en unknown
- 2002-05-24 CZ CZ20033126A patent/CZ20033126A3/cs unknown
- 2002-05-24 AP APAP/P/2003/002911A patent/AP2003002911A0/en unknown
- 2002-05-24 US US10/479,085 patent/US20040171576A1/en not_active Abandoned
- 2002-05-24 CN CNA028106180A patent/CN1535161A/zh active Pending
- 2002-05-24 HU HU0400029A patent/HUP0400029A2/hu unknown
- 2002-05-24 IL IL15877402A patent/IL158774A0/xx unknown
- 2002-05-24 PL PL02366899A patent/PL366899A1/xx unknown
- 2002-05-24 EE EEP200300586A patent/EE200300586A/et unknown
- 2002-05-24 KR KR10-2003-7015411A patent/KR20030097901A/ko not_active Ceased
- 2002-05-24 SV SV2002001055A patent/SV2003001055A/es not_active Application Discontinuation
- 2002-05-24 PA PA20028546101A patent/PA8546101A1/es unknown
- 2002-05-24 MX MXPA03010787A patent/MXPA03010787A/es unknown
-
2003
- 2003-11-18 CO CO03101662A patent/CO5540324A2/es not_active Application Discontinuation
- 2003-11-20 MA MA27409A patent/MA27028A1/fr unknown
- 2003-11-24 NO NO20035202A patent/NO20035202D0/no not_active Application Discontinuation
- 2003-11-24 BG BG108383A patent/BG108383A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL158774A0 (en) | 2004-05-12 |
| SV2003001055A (es) | 2003-11-14 |
| US20040171576A1 (en) | 2004-09-02 |
| PL366899A1 (en) | 2005-02-07 |
| PA8546101A1 (es) | 2003-12-10 |
| WO2002096462A1 (en) | 2002-12-05 |
| CN1535161A (zh) | 2004-10-06 |
| EP1395287A1 (en) | 2004-03-10 |
| OA12609A (en) | 2006-06-09 |
| BG108383A (bg) | 2004-08-31 |
| BR0209986A (pt) | 2004-04-06 |
| MA27028A1 (fr) | 2004-12-20 |
| NO20035202D0 (no) | 2003-11-24 |
| AP2003002911A0 (en) | 2003-12-31 |
| HUP0400029A2 (hu) | 2004-04-28 |
| SK14302003A3 (sk) | 2004-08-03 |
| MXPA03010787A (es) | 2004-03-02 |
| CZ20033126A3 (cs) | 2004-09-15 |
| KR20030097901A (ko) | 2003-12-31 |
| CO5540324A2 (es) | 2005-07-29 |
| CA2448086A1 (en) | 2002-12-05 |
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