EE200300328A - IL-18 inhibiitorite kasutamine südamehaiguse raviks ja/või ennetamiseks - Google Patents

IL-18 inhibiitorite kasutamine südamehaiguse raviks ja/või ennetamiseks

Info

Publication number: EE200300328A
Authority: EE; Estonia
Prior art keywords: inhibitors; prevention; treatment; heart disease; heart
Prior art date: 2001-01-29

Application number

EEP200300328A

Other languages

English (en)

Inventor

Dinarello Charles

Pomerantz Benjamin

Reznikov Leonid

Harken Alden

Chvatchko Yolande

Original Assignee

Applied Research Systems Ars Holding N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-29

Filing date

2002-01-28

Publication date

2003-10-15

2002-01-28 Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.

2003-10-15 Publication of EE200300328A publication Critical patent/EE200300328A/et

2012-04-16 Publication of EE05534B1 publication Critical patent/EE05534B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Cell Biology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

EEP200300328A 2001-01-29 2002-01-28 IL-18 inhibiitorite kasutamine ravimi valmistamiseks kardiomopaatia raviks ja/v?i ennetamiseks EE05534B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01101959		2001-01-29
PCT/EP2002/000844 WO2002060479A1 (en)	2001-01-29	2002-01-28	Use of il-18 inhibitors for the treatment and/or prevention of heart disease

Publications (2)

Publication Number	Publication Date
EE200300328A true EE200300328A (et)	2003-10-15
EE05534B1 EE05534B1 (et)	2012-04-16

Family

ID=8176323

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300328A EE05534B1 (et)	2001-01-29	2002-01-28	IL-18 inhibiitorite kasutamine ravimi valmistamiseks kardiomopaatia raviks ja/v?i ennetamiseks

Country Status (31)

Country	Link
US (1)	US20040234523A1 (et)
EP (1)	EP1355668B1 (et)
JP (2)	JP4860897B2 (et)
KR (1)	KR100857376B1 (et)
CN (1)	CN1326562C (et)
AR (1)	AR032422A1 (et)
AT (1)	ATE380558T1 (et)
BG (1)	BG66483B1 (et)
BR (1)	BR0206819A (et)
CA (1)	CA2435466C (et)
CY (1)	CY1107203T1 (et)
CZ (1)	CZ305653B6 (et)
DE (1)	DE60224004T2 (et)
DK (1)	DK1355668T3 (et)
EA (2)	EA010180B1 (et)
EE (1)	EE05534B1 (et)
ES (1)	ES2295332T3 (et)
HR (1)	HRP20030609A2 (et)
HU (1)	HU229164B1 (et)
IL (2)	IL157024A0 (et)
ME (1)	ME00549B (et)
MX (1)	MXPA03006776A (et)
NO (1)	NO331083B1 (et)
PL (1)	PL213568B1 (et)
PT (1)	PT1355668E (et)
RS (1)	RS51125B (et)
SI (1)	SI1355668T1 (et)
SK (1)	SK287620B6 (et)
UA (1)	UA80676C2 (et)
WO (1)	WO2002060479A1 (et)
ZA (1)	ZA200305439B (et)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102206277A (zh)	2000-02-10	2011-10-05	雅培制药有限公司	结合人白介素-18的抗体及制备和使用方法
CA2424983A1 (en)	2000-10-11	2002-04-18	Viron Therapeutics, Inc.	Nucleic acid molecules and polypeptides for immune modulation
US7718368B2 (en)	2000-12-04	2010-05-18	Viron Therapeutics Inc.	Immunomodulatory protein and useful embodiments thereof
US20080076708A1 (en)	2003-05-13	2008-03-27	Valter Altarocca	Active Variants of the Il-18 Binding Protein and Medical Uses Thereof
US7968684B2 (en)	2003-11-12	2011-06-28	Abbott Laboratories	IL-18 binding proteins
JP4961559B2 (ja) *	2004-03-11	2012-06-27	友昭星野	インターロイキン１８阻害剤を有効成分とする疾患の予防又は治療剤
PL1885753T3 (pl)	2005-06-03	2011-12-30	Ares Trading Sa	Wytwarzanie rekombinowanego białka wiążącego IL-18
ATE529433T1 (de)	2005-06-10	2011-11-15	Ares Trading Sa	Verfahren zur reinigung eines il-18-bindenden proteins
AU2008324814B2 (en) *	2007-11-05	2013-05-16	Solventum Intellectual Properties Company	Identification of tissue for debridement
JOP20200308A1 (ar)	2012-09-07	2017-06-16	Novartis Ag	جزيئات إرتباط il-18
KR102321172B1 (ko) *	2013-09-05	2021-11-05	에이비2 바이오 에스에이	염증성 질환에서 il-18 결합 단백질(ｉｌ-18ｂｐ)
CA2972689A1 (en) *	2015-03-05	2016-09-09	Ab2 Bio Sa	Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases
WO2018013509A1 (en) *	2016-07-11	2018-01-18	Arizona Board Of Regents On Behalf Of The University Of Arizona	Compositions and methods for diagnosing and treating arrhythmias

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6204261B1 (en) *	1995-12-20	2001-03-20	Vertex Pharmaceuticals Incorporated	Inhibitors of interleukin-1β Converting enzyme inhibitors
US5605690A (en) *	1989-09-05	1997-02-25	Immunex Corporation	Methods of lowering active TNF-α levels in mammals using tumor necrosis factor receptor
NZ322197A (en) *	1995-11-21	1999-02-25	Yamanouchi Pharma Co Ltd	Pyrido[2,3-d] pyrimidine derivatives and pharmaceutical compositions thereof
CA2265853C (en) *	1996-09-12	2010-08-03	Idun Pharmaceuticals, Inc.	Inhibition of apoptosis using interleukin-1.beta.-converting enzyme (ice)/ced-3 family inhibitors
JP4094066B2 (ja) *	1996-12-06	2008-06-04	バーテックスファーマシューティカルズインコーポレイテッド	インターロイキン−１β変換酵素のインヒビター
WO1998041232A2 (en) *	1997-03-18	1998-09-24	Basf Aktiengesellschaft	Compositions for modulating responsiveness to corticosteroids
IL121860A0 (en) *	1997-08-14	1998-02-22	Yeda Res & Dev	Interleukin-18 binding proteins their preparation and use
DE19743687C1 (de) *	1997-10-06	1998-11-26	Henkel Kgaa	Detergensgemische und deren Verwendung
WO2000000490A2 (en) *	1998-06-26	2000-01-06	Eli Lilly And Company	5-ht1f agonists
CA2340579A1 (en) *	1998-09-01	2000-03-09	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Interleukin 18-binding protein
EP1022027A1 (en) *	1999-01-22	2000-07-26	Applied Research Systems ARS Holding N.V.	Tumor necrosis factor antagonists and their use in endometriosis
ATE336480T1 (de) *	1999-03-16	2006-09-15	Cytovia Inc	Substituierte 2-aminobenzamin caspase inhibitoren und ihre verwendung
JP2002541237A (ja) *	1999-04-09	2002-12-03	サイトビアインコーポレイテッド	カスパーゼインヒビターおよびその使用
WO2001003719A2 (en) *	1999-07-09	2001-01-18	Amgen Inc.	Combination therapy for conditions leading to bone loss
CN102206277A (zh) *	2000-02-10	2011-10-05	雅培制药有限公司	结合人白介素-18的抗体及制备和使用方法
EA007014B1 (ru) *	2000-05-05	2006-06-30	Апплайд Резеч Системз Арс Холдинг Н.В.	Применение il-18 в качестве диагностического маркера
AU2002224417A1 (en) *	2000-10-18	2002-04-29	Immunex Corporation	Methods for treating il-18 mediated disorders

2002
- 2002-01-28 CZ CZ2003-2335A patent/CZ305653B6/cs not_active IP Right Cessation
- 2002-01-28 BR BR0206819-2A patent/BR0206819A/pt not_active Application Discontinuation
- 2002-01-28 UA UA2003088056A patent/UA80676C2/uk unknown
- 2002-01-28 RS YUP-578/03A patent/RS51125B/sr unknown
- 2002-01-28 ME MEP-2008-681A patent/ME00549B/me unknown
- 2002-01-28 US US10/470,303 patent/US20040234523A1/en not_active Abandoned
- 2002-01-28 JP JP2002560670A patent/JP4860897B2/ja not_active Expired - Lifetime
- 2002-01-28 SK SK1089-2003A patent/SK287620B6/sk not_active IP Right Cessation
- 2002-01-28 EP EP02718052A patent/EP1355668B1/en not_active Expired - Lifetime
- 2002-01-28 ZA ZA200305439A patent/ZA200305439B/en unknown
- 2002-01-28 CA CA2435466A patent/CA2435466C/en not_active Expired - Lifetime
- 2002-01-28 EE EEP200300328A patent/EE05534B1/et unknown
- 2002-01-28 DK DK02718052T patent/DK1355668T3/da active
- 2002-01-28 PL PL366802A patent/PL213568B1/pl unknown
- 2002-01-28 EA EA200501549A patent/EA010180B1/ru not_active IP Right Cessation
- 2002-01-28 MX MXPA03006776A patent/MXPA03006776A/es active IP Right Grant
- 2002-01-28 HR HR20030609A patent/HRP20030609A2/xx not_active Application Discontinuation
- 2002-01-28 KR KR1020037009941A patent/KR100857376B1/ko not_active Expired - Lifetime
- 2002-01-28 PT PT02718052T patent/PT1355668E/pt unknown
- 2002-01-28 WO PCT/EP2002/000844 patent/WO2002060479A1/en not_active Ceased
- 2002-01-28 IL IL15702402A patent/IL157024A0/xx unknown
- 2002-01-28 ES ES02718052T patent/ES2295332T3/es not_active Expired - Lifetime
- 2002-01-28 AT AT02718052T patent/ATE380558T1/de active
- 2002-01-28 SI SI200230667T patent/SI1355668T1/sl unknown
- 2002-01-28 DE DE60224004T patent/DE60224004T2/de not_active Expired - Lifetime
- 2002-01-28 HU HU0303306A patent/HU229164B1/hu unknown
- 2002-01-28 EA EA200300844A patent/EA006767B1/ru not_active IP Right Cessation
- 2002-01-28 CN CNB02807503XA patent/CN1326562C/zh not_active Expired - Lifetime
- 2002-01-29 AR ARP020100315A patent/AR032422A1/es unknown
2003
- 2003-07-16 NO NO20033228A patent/NO331083B1/no not_active IP Right Cessation
- 2003-07-20 IL IL157024A patent/IL157024A/en active IP Right Grant
- 2003-08-25 BG BG108128A patent/BG66483B1/bg unknown
2008
- 2008-02-18 CY CY20081100195T patent/CY1107203T1/el unknown
- 2008-12-16 JP JP2008319532A patent/JP2009102354A/ja active Pending

Also Published As

Publication number	Publication date
MXPA03006776A (es)	2003-10-24
KR100857376B1 (ko)	2008-09-05
PL366802A1 (en)	2005-02-07
CZ20032335A3 (en)	2004-07-14
JP2009102354A (ja)	2009-05-14
HK1062810A1 (en)	2004-11-26
IL157024A0 (en)	2004-02-08
PL213568B1 (pl)	2013-03-29
HUP0303306A2 (hu)	2004-01-28
SK287620B6 (sk)	2011-04-05
EA200300844A1 (ru)	2003-12-25
WO2002060479A1 (en)	2002-08-08
BG66483B1 (bg)	2015-03-31
DK1355668T3 (da)	2008-05-05
CN1499982A (zh)	2004-05-26
ES2295332T3 (es)	2008-04-16
CZ305653B6 (cs)	2016-01-27
CY1107203T1 (el)	2012-11-21
DE60224004D1 (de)	2008-01-24
ME00549B (me)	2011-10-10
NO331083B1 (no)	2011-10-03
US20040234523A1 (en)	2004-11-25
EP1355668A1 (en)	2003-10-29
EP1355668B1 (en)	2007-12-12
IL157024A (en)	2014-02-27
RS51125B (sr)	2010-10-31
BR0206819A (pt)	2004-02-03
YU57803A (sh)	2006-05-25
JP2004522748A (ja)	2004-07-29
UA80676C2 (en)	2007-10-25
PT1355668E (pt)	2008-01-04
EA010180B1 (ru)	2008-06-30
DE60224004T2 (de)	2009-07-23
CA2435466A1 (en)	2002-08-08
NO20033228L (no)	2003-09-26
ATE380558T1 (de)	2007-12-15
CN1326562C (zh)	2007-07-18
SK10892003A3 (sk)	2004-02-03
EE05534B1 (et)	2012-04-16
HUP0303306A3 (en)	2005-12-28
HU229164B1 (en)	2013-09-30
EA200501549A1 (ru)	2006-04-28
KR20030070143A (ko)	2003-08-27
BG108128A (bg)	2004-11-30
JP4860897B2 (ja)	2012-01-25
NO20033228D0 (no)	2003-07-16
ZA200305439B (en)	2004-07-15
HRP20030609A2 (en)	2005-06-30
AR032422A1 (es)	2003-11-05
EA006767B1 (ru)	2006-04-28
SI1355668T1 (sl)	2008-06-30
CA2435466C (en)	2012-04-03

Publication	Publication Date	Title
SI1487541T1 (sl)	2009-02-28	Uporaba inhibitorjev il-18 za zdravljenje in /alipreventivo bolezni perifernega oĺ˝ilja
DE60237823D1 (de)	2010-11-11	Medizinisches behandlungsinstrument
HUP0401127A3 (en)	2006-03-28	Treatment and diagnosis of macrophage disease
DE60322451D1 (de)	2008-09-04	4-Tetrazolyl-4-Phenylpiperidinderivate zur Schmerzbehandlung
NO20034590D0 (no)	2003-10-13	Fremgangsmåter for behandling av vaskul¶r sykdom
NO20044195L (no)	2004-10-01	Biofosfoninsyrer for behandling og prevensjon av osteoprose
SI1627639T1 (sl)	2010-04-30	Uporaba inhibitorjev COX-2 za zdravljenje afektivnih motenj
FIU20060389U0 (fi)	2006-09-22	Luusairauksien hoito
EE200300585A (et)	2004-04-15	PDE4 inhibiitori ja antikolinergilise vahendi kombinatsioon obstruktiivsete hingamisteede haiguste raviks
PT1411926E (pt)	2005-10-31	Inibidores de integrina para o tratamento de doencas oftalmicas
NO20050569D0 (no)	2005-02-02	Fremgangsmate for behandling av alvorlig hjertesvikt og medikament for dette
ZA200208228B (en)	2005-07-27	Use of il-18 inhibitors for the treatment and/or prevention of athesclerosis
IS6966A (is)	2003-09-24	Cýanó-tengd díhýdrópýrimídín efnasambönd og notkun þeirra við meðhöndlun sjúkdóma
EE200300328A (et)	2003-10-15	IL-18 inhibiitorite kasutamine südamehaiguse raviks ja/või ennetamiseks
NO20041214L (no)	2004-06-24	Substituerte benzimidazolforbindelser og deres anvendelse for behandling av cancer
IS6967A (is)	2003-09-24	Ný cýanó-tengd díhýdrópýrimídín efnasambönd og notkun þeirra við meðhöndlun sjúkdóma
NO20054913D0 (no)	2005-10-24	Anvendelse av clustein for behandling og/eller forebyggelse av perifere nevrologiske lidelser
DE60222664D1 (de)	2007-11-08	Hautbehandlungsmittel
FI20021617A7 (fi)	2003-07-25	Diagnostisia ja terapeuttisia menetelmiä
EE200300057A (et)	2004-12-15	Koostis vähi profülaktikaks ja raviks
NO20042476L (no)	2004-06-14	Anvendelse av desoxypeganin for behandling av klinisk depresjon
PT1381620E (pt)	2006-06-30	Dissacaridos hipersulfatados e metodos de utilizacao dos mesmos para o tratamento de inflamacoes
EE200300570A (et)	2004-04-15	Imidasotriasinoonide derivaadid ja nende kasutamine põletikuliste protsesside ja/või immuunhaigustevastu
NO20043113L (no)	2004-09-01	Fremgangsmate for behandling av benforstyrrelse
NO20042166L (no)	2004-05-25	Kombinasjonsterapi for behandling av sykdom

Legal Events

Date	Code	Title	Description
2007-10-15	GB1A	Change in the ownership or in the address of the owner
2012-04-16	HC1A	Change of owner name