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EE200000062A - Dibensotiasepiini kristalliline derivaat ja selle kasutamine antipsühhootilise agensina - Google Patents

Dibensotiasepiini kristalliline derivaat ja selle kasutamine antipsühhootilise agensina

Info

Publication number
EE200000062A
EE200000062A EEP200000062A EEP200000062A EE200000062A EE 200000062 A EE200000062 A EE 200000062A EE P200000062 A EEP200000062 A EE P200000062A EE P200000062 A EEP200000062 A EE P200000062A EE 200000062 A EE200000062 A EE 200000062A
Authority
EE
Estonia
Prior art keywords
crystalline
füä1
ethylü
dibenzoäb
hydroxyethoxy
Prior art date
Application number
EEP200000062A
Other languages
English (en)
Inventor
William Snape Evan
Original Assignee
Zeneca Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeneca Limited filed Critical Zeneca Limited
Publication of EE200000062A publication Critical patent/EE200000062A/et
Publication of EE04550B1 publication Critical patent/EE04550B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Liquid Crystal Substances (AREA)
EEP200000062A 1997-08-01 1998-07-28 Dibensotiasepiini kristalliline derivaat, selle saamise protsess, selle kasutamine ravimitootmiseks ja seda sisaldav farmatseutiline kompositsioon EE04550B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9716161.6A GB9716161D0 (en) 1997-08-01 1997-08-01 Process
PCT/GB1998/002260 WO1999006381A1 (en) 1997-08-01 1998-07-28 A crystalline dibenzothiazepine derivative and its use as an antipsychotic agent

Publications (2)

Publication Number Publication Date
EE200000062A true EE200000062A (et) 2000-10-16
EE04550B1 EE04550B1 (et) 2005-10-17

Family

ID=10816746

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000062A EE04550B1 (et) 1997-08-01 1998-07-28 Dibensotiasepiini kristalliline derivaat, selle saamise protsess, selle kasutamine ravimitootmiseks ja seda sisaldav farmatseutiline kompositsioon

Country Status (31)

Country Link
US (2) US6372734B1 (et)
EP (2) EP1000043B1 (et)
JP (2) JP2001512109A (et)
KR (1) KR20010022241A (et)
CN (1) CN1125058C (et)
AT (2) ATE444959T1 (et)
AU (1) AU739255B2 (et)
BG (1) BG64796B1 (et)
BR (1) BR9811061A (et)
CA (1) CA2295792C (et)
CY (2) CY2200162T2 (et)
CZ (1) CZ299225B6 (et)
DE (4) DE05011169T1 (et)
EE (1) EE04550B1 (et)
ES (2) ES2296575T3 (et)
GB (2) GB9716161D0 (et)
HU (1) HU228620B1 (et)
ID (1) ID24219A (et)
IL (1) IL133618A (et)
MY (1) MY120999A (et)
NO (1) NO20000484L (et)
NZ (1) NZ501914A (et)
PL (1) PL338384A1 (et)
PT (2) PT1000043E (et)
RU (1) RU2224754C2 (et)
SI (2) SI1589008T1 (et)
SK (1) SK287145B6 (et)
TR (1) TR200000848T2 (et)
TW (1) TW533207B (et)
WO (1) WO1999006381A1 (et)
ZA (1) ZA986904B (et)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2000141A1 (en) * 2002-03-20 2008-12-10 Teva Pharmaceutical Industries Ltd. Methods for preparing crystalline quetiapine hemifumarate
WO2004076431A1 (en) * 2003-02-22 2004-09-10 Teva Pharmaceutical Industries Ltd. Synthesis of quetiapine and pharmaceutically acceptable salts thereof
AU2003216705A1 (en) * 2003-03-03 2004-09-28 Hetero Drugs Limited Novel polymorphs of quetiapine fumarate
WO2004089957A1 (en) * 2003-04-07 2004-10-21 Hetero Drugs Limited A novel crystalline form of dorzolamide hydrochloride
ES2223294B2 (es) 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
US20060081361A1 (en) * 2004-09-13 2006-04-20 Gabbey Lawrence W Oil cooler with integral filter
WO2006035293A1 (en) * 2004-09-27 2006-04-06 Ranbaxy Laboratories Limited Polymorphic forms of quetiapine hemifumarate
GB0425729D0 (en) * 2004-11-23 2004-12-22 Pliva Res & Dev Ltd Heterocyclic compounds
WO2006056772A2 (en) * 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Salts of quetiapine
ES2234447B1 (es) * 2005-03-07 2006-03-01 Union Quimico-Farmaceutica S.A. Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
EP1869007A1 (en) 2005-04-14 2007-12-26 Teva Pharmaceutical Industries Ltd Process for preparing quetiapine fumarate
US20070072840A1 (en) * 2005-05-30 2007-03-29 Pandya Bhargav Polymorphic forms of quetiapine
US8044038B2 (en) * 2005-09-30 2011-10-25 Fermion Oy Crystallization process of quetiapine hemifumarate
US8044039B2 (en) 2005-10-28 2011-10-25 Fermion Oy Quetiapine hemifumarate purification by crystallization
JP2009516705A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 塩の形態
US8389510B2 (en) * 2005-11-18 2013-03-05 Astrazeneca Ab Crystalline forms
JP2009516708A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 液体製剤
JP2009516706A (ja) * 2005-11-18 2009-04-23 アストラゼネカ・アクチエボラーグ 結晶形
EP1951693A4 (en) * 2005-11-18 2012-05-30 Astrazeneca Ab SOLID FORMULATIONS
CZ300451B6 (cs) * 2006-07-03 2009-05-20 Farmak, A. S. Zpusob prípravy solí 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolu (quetiapinu) a jejich cištení
WO2008066620A2 (en) * 2006-10-20 2008-06-05 Concert Pharmaceuticals Inc. Dibenzothiazepine derivatives
DE602007009036D1 (de) 2007-02-14 2010-10-21 Lesvi Laboratorios Sl Pharmazeutische Zusammensetzungen mit Quetiapinfumarat
JP2009529062A (ja) * 2007-03-29 2009-08-13 テバ ファーマシューティカル インダストリーズ リミティド フマル酸クエチアピンを調製するための改良法
WO2009004480A2 (en) * 2007-05-07 2009-01-08 Actavis Group Ptc Ehf Quetiapine salts and their polymorphs
US20090082334A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched quetiapine
CA2706903C (en) * 2007-12-05 2015-11-17 Henricus Jacobus Maria Gijsen Dibenzoazepine and dibenzooxazepine trpa1 agonists
DE202009018024U1 (de) 2008-08-01 2010-12-09 Krka Tovarna Zdravil, D.D., Novo Mesto Quetiapin-Zusammensetzung
WO2010033270A1 (en) * 2008-09-17 2010-03-25 Auspex Pharmaceuticals, Inc. Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
EP2403841A1 (en) 2009-03-04 2012-01-11 Ranbaxy Laboratories Limited Process for the preparation of quetiapine fumarate
WO2013024072A1 (en) 2011-08-12 2013-02-21 Qiagen Gmbh Method for isolating nucleic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787249A (fr) 1971-08-05 1973-02-05 Squibb & Sons Inc Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
GB8705574D0 (en) 1987-03-10 1987-04-15 Ici Plc Preparation of thiazepine compound

Also Published As

Publication number Publication date
EP1589008B1 (en) 2011-01-19
GB9716161D0 (en) 1997-10-08
TW533207B (en) 2003-05-21
US20020147186A1 (en) 2002-10-10
HUP0002663A2 (hu) 2001-09-28
EP1589008A1 (en) 2005-10-26
JP2001512109A (ja) 2001-08-21
RU2224754C2 (ru) 2004-02-27
ID24219A (id) 2000-07-13
NZ501914A (en) 2001-09-28
NO20000484D0 (no) 2000-01-31
ATE496037T1 (de) 2011-02-15
CY2200162T2 (el) 2010-07-28
HK1029992A1 (en) 2001-04-20
IL133618A (en) 2004-02-08
IL133618A0 (en) 2001-04-30
GB9814882D0 (en) 1998-09-09
TR200000848T2 (tr) 2000-08-21
BR9811061A (pt) 2000-09-19
CA2295792C (en) 2007-04-17
DE69842104D1 (de) 2011-03-03
PT1000043E (pt) 2009-11-30
ZA986904B (en) 1999-02-01
HUP0002663A3 (en) 2001-10-29
HK1081962A1 (en) 2006-05-26
NO20000484L (no) 2000-03-16
SK287145B6 (sk) 2010-01-07
JP2009102345A (ja) 2009-05-14
CZ299225B6 (cs) 2008-05-21
CN1125058C (zh) 2003-10-22
DE98936529T1 (de) 2008-11-20
EP1000043A1 (en) 2000-05-17
SK1302000A3 (en) 2000-06-12
ES2296568T1 (es) 2008-05-01
AU739255B2 (en) 2001-10-04
ES2296575T1 (es) 2008-05-01
BG104176A (en) 2000-08-31
ATE444959T1 (de) 2009-10-15
PL338384A1 (en) 2000-10-23
CA2295792A1 (en) 1999-02-11
ES2296568T3 (es) 2011-05-06
WO1999006381A1 (en) 1999-02-11
PT1589008E (pt) 2011-03-23
KR20010022241A (ko) 2001-03-15
EE04550B1 (et) 2005-10-17
DE05011169T1 (de) 2008-11-06
BG64796B1 (bg) 2006-04-28
CN1265101A (zh) 2000-08-30
EP1000043B1 (en) 2009-10-07
DE69841216D1 (de) 2009-11-19
AU8549898A (en) 1999-02-22
MY120999A (en) 2005-12-30
US6372734B1 (en) 2002-04-16
CY2200161T2 (el) 2010-07-28
SI1589008T1 (sl) 2011-04-29
CZ2000341A3 (cs) 2000-05-17
ES2296575T3 (es) 2010-02-05
HU228620B1 (en) 2013-04-29
SI1000043T1 (sl) 2010-01-29

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KB4A Valid patent at the end of a year

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Effective date: 20160728