EE200000024A - Meetod alküüloksüfuranooni amiinderivaatide valmistamiseks, sel meetodil saadud ühendid ja nende kasutamine - Google Patents

Meetod alküüloksüfuranooni amiinderivaatide valmistamiseks, sel meetodil saadud ühendid ja nende kasutamine

Info

Publication number: EE200000024A
Authority: EE; Estonia
Prior art keywords: alkyloxfuranone; preparation; compounds obtained; amine derivatives; amine
Prior art date: 1997-07-15

Application number

EEP200000024A

Other languages

English (en)

Inventor

Bouchet Rapha�l

Brion Francis

Colladant Colette

Lagouardat Jacques

Original Assignee

Hoechst Marion Roussel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-15

Filing date

1998-07-09

Publication date

2000-10-16

1998-07-09 Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel

2000-10-16 Publication of EE200000024A publication Critical patent/EE200000024A/et

2002-10-15 Publication of EE03873B1 publication Critical patent/EE03873B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/60—Two oxygen atoms, e.g. succinic anhydride
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

EEP200000024A 1997-07-15 1998-07-09 Meetod alküüloksüfuranooni amiinderivaatide valmistamiseks, sel meetodil saadud ühendid ja nende kasutamine EE03873B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9708932A FR2766188B1 (fr)	1997-07-15	1997-07-15	Nouveau procede de preparation de derives amines d'alkyloxy furanone, composes issus de ce procede et utilisation de ces composes
PCT/FR1998/001480 WO1999003852A1 (fr)	1997-07-15	1998-07-09	Procede de preparation de derives amines d'alkyloxyfuranone, composes issus de ce procede et utilisation de ces composes

Publications (2)

Publication Number	Publication Date
EE200000024A true EE200000024A (et)	2000-10-16
EE03873B1 EE03873B1 (et)	2002-10-15

Family

ID=9509210

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200000024A EE03873B1 (et)	1997-07-15	1998-07-09	Meetod alküüloksüfuranooni amiinderivaatide valmistamiseks, sel meetodil saadud ühendid ja nende kasutamine

Country Status (34)

Country	Link
US (1)	US6235899B1 (et)
EP (1)	EP0998470B1 (et)
JP (1)	JP4450987B2 (et)
KR (1)	KR100519691B1 (et)
CN (1)	CN100363355C (et)
AP (1)	AP1071A (et)
AR (1)	AR015924A1 (et)
AT (1)	ATE239713T1 (et)
AU (1)	AU744272B2 (et)
BG (1)	BG64050B1 (et)
BR (1)	BR9810896A (et)
CA (1)	CA2296742C (et)
CZ (1)	CZ295312B6 (et)
DE (1)	DE69814395T2 (et)
DK (1)	DK0998470T3 (et)
EA (1)	EA002883B1 (et)
EE (1)	EE03873B1 (et)
ES (1)	ES2197489T3 (et)
FR (1)	FR2766188B1 (et)
HR (1)	HRP20000027B1 (et)
HU (1)	HU230148B1 (et)
ID (1)	ID23784A (et)
IL (1)	IL134031A (et)
ME (1)	ME01708B (et)
NO (1)	NO324508B1 (et)
NZ (1)	NZ502338A (et)
PL (1)	PL200820B1 (et)
PT (1)	PT998470E (et)
RS (1)	RS49832B (et)
SK (1)	SK284168B6 (et)
TR (1)	TR200000117T2 (et)
UA (1)	UA66364C2 (et)
WO (1)	WO1999003852A1 (et)
ZA (1)	ZA986203B (et)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7053056B2 (en)	1998-07-02	2006-05-30	Idun Pharmaceuticals, Inc.	C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
RU2002135317A (ru) *	2000-04-24	2004-04-10	Вертекс Фармасьютикалз Инкорпорейтед (Us)	Способ и промежуточные соединения для получения замещенных ацеталей аспарагиновой кислоты
PE20011350A1 (es)	2000-05-19	2002-01-15	Vertex Pharma	PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
JP2003327568A (ja) *	2000-09-20	2003-11-19	Kanegafuchi Chem Ind Co Ltd	光学活性β−アミノ酸誘導体の製造方法
JPWO2002055478A1 (ja) *	2001-01-16	2004-05-13	鐘淵化学工業株式会社	光学活性アミノラクトン誘導体の製造法およびその中間体
JP2007525503A (ja)	2004-02-27	2007-09-06	バーテックス　ファーマシューティカルズ　インコーポレイテッド	カスパーゼインヒビターおよびそれらの使用
SI2399915T1 (sl) *	2004-03-12	2015-05-29	Vertex Pharmaceuticals Incorporated	Postopek in intermediati za pripravo inhibitorjev asparagin-acetal-kaspaze

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6204261B1 (en) *	1995-12-20	2001-03-20	Vertex Pharmaceuticals Incorporated	Inhibitors of interleukin-1β Converting enzyme inhibitors
US5716929A (en) *	1994-06-17	1998-02-10	Vertex Pharmaceuticals, Inc.	Inhibitors of interleukin-1β converting enzyme

1997
- 1997-07-15 FR FR9708932A patent/FR2766188B1/fr not_active Expired - Lifetime
1998
- 1998-07-09 ES ES98937591T patent/ES2197489T3/es not_active Expired - Lifetime
- 1998-07-09 HU HU0003857A patent/HU230148B1/hu unknown
- 1998-07-09 US US09/463,014 patent/US6235899B1/en not_active Expired - Lifetime
- 1998-07-09 EP EP98937591A patent/EP0998470B1/fr not_active Expired - Lifetime
- 1998-07-09 AP APAP/P/2000/001732A patent/AP1071A/en active
- 1998-07-09 CN CNB98808967XA patent/CN100363355C/zh not_active Expired - Lifetime
- 1998-07-09 KR KR10-2000-7000398A patent/KR100519691B1/ko not_active Expired - Lifetime
- 1998-07-09 IL IL13403198A patent/IL134031A/en not_active IP Right Cessation
- 1998-07-09 RS YUP-15/00A patent/RS49832B/sr unknown
- 1998-07-09 PT PT98937591T patent/PT998470E/pt unknown
- 1998-07-09 CA CA002296742A patent/CA2296742C/fr not_active Expired - Lifetime
- 1998-07-09 AT AT98937591T patent/ATE239713T1/de active
- 1998-07-09 BR BR9810896-4A patent/BR9810896A/pt not_active Application Discontinuation
- 1998-07-09 PL PL338035A patent/PL200820B1/pl unknown
- 1998-07-09 WO PCT/FR1998/001480 patent/WO1999003852A1/fr not_active Ceased
- 1998-07-09 DE DE69814395T patent/DE69814395T2/de not_active Expired - Lifetime
- 1998-07-09 SK SK30-2000A patent/SK284168B6/sk not_active IP Right Cessation
- 1998-07-09 EA EA200000127A patent/EA002883B1/ru not_active IP Right Cessation
- 1998-07-09 TR TR2000/00117T patent/TR200000117T2/xx unknown
- 1998-07-09 ID IDW20000067A patent/ID23784A/id unknown
- 1998-07-09 HR HR20000027A patent/HRP20000027B1/xx not_active IP Right Cessation
- 1998-07-09 ME MEP-2000-15A patent/ME01708B/me unknown
- 1998-07-09 AU AU86333/98A patent/AU744272B2/en not_active Expired
- 1998-07-09 DK DK98937591T patent/DK0998470T3/da active
- 1998-07-09 JP JP2000503076A patent/JP4450987B2/ja not_active Expired - Lifetime
- 1998-07-09 EE EEP200000024A patent/EE03873B1/et unknown
- 1998-07-09 CZ CZ200065A patent/CZ295312B6/cs not_active IP Right Cessation
- 1998-07-09 NZ NZ502338A patent/NZ502338A/en not_active IP Right Cessation
- 1998-07-13 ZA ZA9806203A patent/ZA986203B/xx unknown
- 1998-07-15 AR ARP980103455A patent/AR015924A1/es not_active Application Discontinuation
- 1998-09-07 UA UA2000020800A patent/UA66364C2/uk unknown
2000
- 2000-01-12 BG BG104073A patent/BG64050B1/bg unknown
- 2000-01-14 NO NO20000182A patent/NO324508B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
ME01708B (me)	2008-08-07
WO1999003852A1 (fr)	1999-01-28
SK284168B6 (sk)	2004-10-05
FR2766188B1 (fr)	2000-02-11
HUP0003857A3 (en)	2002-08-28
US6235899B1 (en)	2001-05-22
HRP20000027A2 (en)	2000-10-31
BR9810896A (pt)	2000-09-26
EP0998470A1 (fr)	2000-05-10
FR2766188A1 (fr)	1999-01-22
CA2296742A1 (fr)	1999-01-28
PL200820B1 (pl)	2009-02-27
PT998470E (pt)	2003-09-30
EE03873B1 (et)	2002-10-15
KR100519691B1 (ko)	2005-10-13
DK0998470T3 (da)	2003-09-01
EP0998470B1 (fr)	2003-05-07
NO20000182D0 (no)	2000-01-14
EA200000127A1 (ru)	2000-08-28
CZ200065A3 (cs)	2000-07-12
AP2000001732A0 (en)	2000-03-31
HRP20000027B1 (en)	2006-07-31
EA002883B1 (ru)	2002-10-31
NO324508B1 (no)	2007-11-05
HU230148B1 (hu)	2015-09-28
JP2001510191A (ja)	2001-07-31
AU8633398A (en)	1999-02-10
DE69814395T2 (de)	2003-12-11
AU744272B2 (en)	2002-02-21
IL134031A0 (en)	2001-04-30
NZ502338A (en)	2001-09-28
KR20010021834A (ko)	2001-03-15
DE69814395D1 (de)	2003-06-12
CN100363355C (zh)	2008-01-23
PL338035A1 (en)	2000-09-25
CZ295312B6 (cs)	2005-07-13
ATE239713T1 (de)	2003-05-15
BG64050B1 (bg)	2003-11-28
NO20000182L (no)	2000-03-07
JP4450987B2 (ja)	2010-04-14
AR015924A1 (es)	2001-05-30
ID23784A (id)	2000-05-11
CN1269795A (zh)	2000-10-11
HUP0003857A2 (hu)	2001-04-28
BG104073A (en)	2001-05-31
ES2197489T3 (es)	2004-01-01
SK302000A3 (en)	2000-11-07
IL134031A (en)	2004-06-01
TR200000117T2 (tr)	2000-07-21
ZA986203B (en)	1999-08-18
UA66364C2 (uk)	2004-05-17
CA2296742C (fr)	2009-12-08
YU1500A (sh)	2002-10-18
RS49832B (sr)	2008-08-07
AP1071A (en)	2002-05-20

Publication	Publication Date	Title
EE200000255A (et)	2000-12-15	Vähivastaste ühendite valmistamise protsess ja vaheühendid
NO904802L (no)	1991-05-07	Fremgangsmaate for fremstilling av aromatiske aminforbindelser.
DE69908230D1 (de)	2003-07-03	Verfahren zum Herstellen von Alpha-Hydroxycarboxylaten
EP1023250A4 (en)	2001-03-21	METHOD FOR PRODUCING 2,6-DIALKYLNAPHTHALINE
DK0946531T3 (da)	2006-02-13	Fremgangsmåde til fremstilling af thiazol-derivater
EE200000024A (et)	2000-10-16	Meetod alküüloksüfuranooni amiinderivaatide valmistamiseks, sel meetodil saadud ühendid ja nende kasutamine
DK0946514T3 (da)	2003-08-25	Fremgangsmåde til fremstilling af n-substituerede 3-hydroxypyrazoler
NO20003454L (no)	2000-07-04	FremgangsmÕte for fremstilling av (-)cis-3-hydroksy-1-metyl-4-
TR199800403A3 (tr)	1998-09-21	a-Bromo-laktam türevlerinin hazirlanmasi için yöntem.
DK1075473T3 (da)	2007-11-05	Fremgangsmåde til fremstilling af 1,3-disubstituerede-4-oxocykliske urinstoffer
FI933755A7 (fi)	1993-08-26	Menetelmä trans-piperidiini-2,5-dikarboksylaattien valmistamiseksi
EE200000537A (et)	2001-06-15	Pürasolo[4,3-d]pürimidiin-7-oon-3-püridüülsulfonüülühendite ja nende vaheühendite valmistamise protsess
NO20020308D0 (no)	2002-01-21	Fremgangsmåte for fremstilling av epothiolon B og derivater, såvel som mellomprodukter for fremgangsmåten
FI964429A7 (fi)	1996-11-04	Menetelmä 1-(3-trialkyylisilyylifenyyli)-2,2,2-trifluorimetyylietanoni n johdannaisten valmistamiseksi
DK1202949T3 (da)	2004-07-19	Fremgangsmåde til fremstilling af acylerede 1,3-dicarbonylforbindelser
FI952287A7 (fi)	1995-11-14	Menetelmä 2-amino-4,6-dikloori-pyrimidiinin valmistamiseksi
PL343629A1 (en)	2001-08-27	Improved process for the manufacture of n-(1-cyanoalkyl)-2-phenoxypropionamide derivatives
DK0782982T3 (da)	2000-10-09	Fremgangsmåde til fremstilling af o-chlormethyl-phenylglyoxylsyrederivater
EE200000369A (et)	2001-12-17	Isopropüülmetüül[2-(3-n-propoksüfenoksü)etüül]amiini valmistamise protsess
FI945414A0 (fi)	1994-11-17	Menetelmä N,N-disubstituoidun aminofenolin valmistamiseksi
NO20012811D0 (no)	2001-06-07	Fremgangsmåte for fremstilling av p-klorfenyl-propanol- derivat
DK1080076T3 (da)	2004-03-22	Forbedret fremgangsmåde til fremstilling af farmaceutisk værdifulde norbenzomorphanderivater
FI971964A7 (fi)	1997-05-07	Menetelmä 1-halo-3-trialkyylisilasnyylibentseenijohdannaisten valmista miseksi
NO20013044L (no)	2001-08-20	Fremgangsmåte for fremstilling av NG-substituerte deaza- adenosinderivater
DK1012143T3 (da)	2004-04-19	Fremgangsmåde til fremstilling af 1-phenylpyrazolin-3-carboxylsyrederivater

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-12-15	GB1A	Change in the ownership or in the address of the owner
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231