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NO20000182L - Fremgangsmåte for fremstilling av alkoksyfuranonamin- derivater, forbindelser frembragt ved fremgangsmåten og anvendelse av disse forbindelser - Google Patents

Fremgangsmåte for fremstilling av alkoksyfuranonamin- derivater, forbindelser frembragt ved fremgangsmåten og anvendelse av disse forbindelser

Info

Publication number
NO20000182L
NO20000182L NO20000182A NO20000182A NO20000182L NO 20000182 L NO20000182 L NO 20000182L NO 20000182 A NO20000182 A NO 20000182A NO 20000182 A NO20000182 A NO 20000182A NO 20000182 L NO20000182 L NO 20000182L
Authority
NO
Norway
Prior art keywords
compounds
alkoxyfuranonamine
derivatives
preparation
produced
Prior art date
Application number
NO20000182A
Other languages
English (en)
Other versions
NO20000182D0 (no
NO324508B1 (no
Inventor
Raphaul Bouchet
Francis Brion
Colette Colladant
Jacques Lagouardat
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO20000182D0 publication Critical patent/NO20000182D0/no
Publication of NO20000182L publication Critical patent/NO20000182L/no
Publication of NO324508B1 publication Critical patent/NO324508B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20000182A 1997-07-15 2000-01-14 Fremgangsmate for fremstilling av alkoksyfuranonaminderivater, forbindelser frembrakt ved fremgangsmaten og anvendelse av disse forbindelser NO324508B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9708932A FR2766188B1 (fr) 1997-07-15 1997-07-15 Nouveau procede de preparation de derives amines d'alkyloxy furanone, composes issus de ce procede et utilisation de ces composes
PCT/FR1998/001480 WO1999003852A1 (fr) 1997-07-15 1998-07-09 Procede de preparation de derives amines d'alkyloxyfuranone, composes issus de ce procede et utilisation de ces composes

Publications (3)

Publication Number Publication Date
NO20000182D0 NO20000182D0 (no) 2000-01-14
NO20000182L true NO20000182L (no) 2000-03-07
NO324508B1 NO324508B1 (no) 2007-11-05

Family

ID=9509210

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000182A NO324508B1 (no) 1997-07-15 2000-01-14 Fremgangsmate for fremstilling av alkoksyfuranonaminderivater, forbindelser frembrakt ved fremgangsmaten og anvendelse av disse forbindelser

Country Status (34)

Country Link
US (1) US6235899B1 (no)
EP (1) EP0998470B1 (no)
JP (1) JP4450987B2 (no)
KR (1) KR100519691B1 (no)
CN (1) CN100363355C (no)
AP (1) AP1071A (no)
AR (1) AR015924A1 (no)
AT (1) ATE239713T1 (no)
AU (1) AU744272B2 (no)
BG (1) BG64050B1 (no)
BR (1) BR9810896A (no)
CA (1) CA2296742C (no)
CZ (1) CZ295312B6 (no)
DE (1) DE69814395T2 (no)
DK (1) DK0998470T3 (no)
EA (1) EA002883B1 (no)
EE (1) EE03873B1 (no)
ES (1) ES2197489T3 (no)
FR (1) FR2766188B1 (no)
HR (1) HRP20000027B1 (no)
HU (1) HU230148B1 (no)
ID (1) ID23784A (no)
IL (1) IL134031A (no)
ME (1) ME01708B (no)
NO (1) NO324508B1 (no)
NZ (1) NZ502338A (no)
PL (1) PL200820B1 (no)
PT (1) PT998470E (no)
RS (1) RS49832B (no)
SK (1) SK284168B6 (no)
TR (1) TR200000117T2 (no)
UA (1) UA66364C2 (no)
WO (1) WO1999003852A1 (no)
ZA (1) ZA986203B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7053056B2 (en) 1998-07-02 2006-05-30 Idun Pharmaceuticals, Inc. C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
RU2002135317A (ru) * 2000-04-24 2004-04-10 Вертекс Фармасьютикалз Инкорпорейтед (Us) Способ и промежуточные соединения для получения замещенных ацеталей аспарагиновой кислоты
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
JP2003327568A (ja) * 2000-09-20 2003-11-19 Kanegafuchi Chem Ind Co Ltd 光学活性β−アミノ酸誘導体の製造方法
JPWO2002055478A1 (ja) * 2001-01-16 2004-05-13 鐘淵化学工業株式会社 光学活性アミノラクトン誘導体の製造法およびその中間体
JP2007525503A (ja) 2004-02-27 2007-09-06 バーテックス　ファーマシューティカルズ　インコーポレイテッド カスパーゼインヒビターおよびそれらの使用
SI2399915T1 (sl) * 2004-03-12 2015-05-29 Vertex Pharmaceuticals Incorporated Postopek in intermediati za pripravo inhibitorjev asparagin-acetal-kaspaze

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5716929A (en) * 1994-06-17 1998-02-10 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme

Also Published As

Publication number Publication date
ME01708B (me) 2008-08-07
WO1999003852A1 (fr) 1999-01-28
SK284168B6 (sk) 2004-10-05
FR2766188B1 (fr) 2000-02-11
HUP0003857A3 (en) 2002-08-28
US6235899B1 (en) 2001-05-22
HRP20000027A2 (en) 2000-10-31
BR9810896A (pt) 2000-09-26
EP0998470A1 (fr) 2000-05-10
FR2766188A1 (fr) 1999-01-22
CA2296742A1 (fr) 1999-01-28
PL200820B1 (pl) 2009-02-27
PT998470E (pt) 2003-09-30
EE03873B1 (et) 2002-10-15
KR100519691B1 (ko) 2005-10-13
DK0998470T3 (da) 2003-09-01
EP0998470B1 (fr) 2003-05-07
NO20000182D0 (no) 2000-01-14
EA200000127A1 (ru) 2000-08-28
CZ200065A3 (cs) 2000-07-12
AP2000001732A0 (en) 2000-03-31
HRP20000027B1 (en) 2006-07-31
EA002883B1 (ru) 2002-10-31
NO324508B1 (no) 2007-11-05
HU230148B1 (hu) 2015-09-28
JP2001510191A (ja) 2001-07-31
AU8633398A (en) 1999-02-10
DE69814395T2 (de) 2003-12-11
EE200000024A (et) 2000-10-16
AU744272B2 (en) 2002-02-21
IL134031A0 (en) 2001-04-30
NZ502338A (en) 2001-09-28
KR20010021834A (ko) 2001-03-15
DE69814395D1 (de) 2003-06-12
CN100363355C (zh) 2008-01-23
PL338035A1 (en) 2000-09-25
CZ295312B6 (cs) 2005-07-13
ATE239713T1 (de) 2003-05-15
BG64050B1 (bg) 2003-11-28
JP4450987B2 (ja) 2010-04-14
AR015924A1 (es) 2001-05-30
ID23784A (id) 2000-05-11
CN1269795A (zh) 2000-10-11
HUP0003857A2 (hu) 2001-04-28
BG104073A (en) 2001-05-31
ES2197489T3 (es) 2004-01-01
SK302000A3 (en) 2000-11-07
IL134031A (en) 2004-06-01
TR200000117T2 (tr) 2000-07-21
ZA986203B (en) 1999-08-18
UA66364C2 (uk) 2004-05-17
CA2296742C (fr) 2009-12-08
YU1500A (sh) 2002-10-18
RS49832B (sr) 2008-08-07
AP1071A (en) 2002-05-20

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Legal Events

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