EE05644B1 - Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG - Google Patents

Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

Info

Publication number: EE05644B1
Authority: EE; Estonia
Prior art keywords: hcg; recombinant; purifying; purified; purification
Prior art date: 2000-02-22

Application number

EEP200200469A

Other languages

English (en)

Estonian (et)

Inventor

Paradisi Gianfranco

Rossi Mara

Scaglia Laura

Original Assignee

Applied Research Systems Ars Holding N.V.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-22

Filing date

2001-01-22

Publication date

2013-04-15

2001-01-22 Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.

2004-04-15 Publication of EE200200469A publication Critical patent/EE200200469A/xx

2013-04-15 Publication of EE05644B1 publication Critical patent/EE05644B1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Endocrinology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Reproductive Health (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Analytical Chemistry (AREA)
Gynecology & Obstetrics (AREA)
Diabetes (AREA)
Pregnancy & Childbirth (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Detergent Compositions (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)

EEP200200469A 2000-02-22 2001-01-22 Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG EE05644B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00103690		2000-02-22
PCT/EP2001/000665 WO2001062773A1 (en)	2000-02-22	2001-01-22	PROCESS OF PURIFICATION OF hCG AND RECOMBINANT hCG PURIFIED BY THAT METHOD

Publications (2)

Publication Number	Publication Date
EE200200469A EE200200469A (et)	2004-04-15
EE05644B1 true EE05644B1 (et)	2013-04-15

Family

ID=8167925

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200200469A EE05644B1 (et)	2000-02-22	2001-01-22	Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

Country Status (31)

Country	Link
US (2)	US7297777B2 (no)
EP (2)	EP1257564B1 (no)
JP (1)	JP4588960B2 (no)
KR (1)	KR100806911B1 (no)
CN (1)	CN100482679C (no)
AT (1)	ATE406378T1 (no)
AU (2)	AU783320B2 (no)
BG (1)	BG65807B1 (no)
BR (1)	BRPI0108556B8 (no)
CA (1)	CA2399020A1 (no)
CY (1)	CY1108460T1 (no)
CZ (1)	CZ303144B6 (no)
DE (1)	DE60135541D1 (no)
DK (1)	DK1257564T3 (no)
EA (1)	EA006605B1 (no)
EE (1)	EE05644B1 (no)
ES (1)	ES2307585T3 (no)
HR (1)	HRP20020650B1 (no)
HU (2)	HU228935B1 (no)
IL (2)	IL151308A0 (no)
ME (1)	ME00296B (no)
MX (1)	MXPA02007871A (no)
NO (1)	NO328694B1 (no)
PL (1)	PL205149B1 (no)
PT (1)	PT1257564E (no)
RS (1)	RS50741B (no)
SI (1)	SI1257564T1 (no)
SK (1)	SK287146B6 (no)
UA (2)	UA78488C2 (no)
WO (1)	WO2001062773A1 (no)
ZA (1)	ZA200206109B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EE05644B1 (et) *	2000-02-22	2013-04-15	Applied Research Systems Ars Holding N.V.	Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG
EP1709065B1 (en) *	2004-10-04	2010-06-02	Novetide Ltd.	A counterion exchange process for peptides
CN1958603B (zh) *	2005-11-04	2010-05-05	上海天伟生物制药有限公司	一种人绒毛膜促性腺素的纯化方法
EA200802426A1 (ru) *	2006-07-11	2009-04-28	Коваль, Антон Александрович	Применение хорионического или лютеинизирующего гормона для профилактики или лечения возрастного гипогонадизма
CN101397339B (zh) *	2008-09-24	2012-07-25	上海天伟生物制药有限公司	糖蛋白中去除/灭活病毒的方法
TWI532495B (zh)	2009-10-05	2016-05-11	菲瑞茵國際中心股份有限公司	藥學製劑
CN101792481B (zh) *	2010-03-12	2012-05-30	丽珠医药集团股份有限公司	一种绒毛膜促性腺激素的纯化方法
WO2012120535A2 (en) *	2011-02-03	2012-09-13	Sanzyme Limited	A composition comprising highly purified chorionic gonadotropin, it's formulation and uses of the same
CN103619358B (zh)	2011-03-31	2017-02-15	辉凌公司	药物制剂
WO2013102921A2 (en) *	2011-11-17	2013-07-11	Sanzyme Limited	Hcg - newer treatment modality for type 2 diabetes mellitus (t2dm)
CN103288950A (zh) *	2012-12-28	2013-09-11	青岛九龙生物医药有限公司	改进柱分离工序洗涤液和洗脱液配比去除杂质的方法
CN104101656A (zh) *	2013-04-01	2014-10-15	上海天伟生物制药有限公司	一种促性腺激素的纯度测定方法
US20150065426A1 (en) *	2013-08-27	2015-03-05	Professional Compounding Centers Of America	Testosterone Booster Transdermal Compositions
CN105968185A (zh) *	2016-07-20	2016-09-28	宁波人健药业集团股份有限公司	一种绒促性素纯化方法
CN111233999B (zh) *	2020-03-21	2024-02-23	上海浦东明炎生物技术有限公司	一种从人尿中提取人绒毛膜促性腺激素的方法
CN113398251B (zh) *	2021-07-30	2022-08-05	宁波人健药业集团股份有限公司	一种重组人绒毛膜促性腺激素冻干粉针剂及其制备方法
CN116063452A (zh) *	2023-01-03	2023-05-05	杭州浦泰生物科技有限公司	一种人绒毛膜促性腺激素高效纯化方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3045539B2 (ja) *	1989-02-21	2000-05-29	ワシントンユニバーシティ	改変型生殖ホルモン
IT1250075B (it) *	1991-12-18	1995-03-30	Serono Cesare Ist Ricerca	Composizioni farmaceutiche contenenti gonadotropine.
IT1254370B (it)	1992-05-22	1995-09-14	Sorin Biomedica Spa	Procedimento per la purificazione di proteine da sistemi cellulari.
EP0814841B1 (en)	1995-03-21	2001-12-05	Applied Research Systems ARS Holding N.V.	Hcg liquid formulations
CN1082368C (zh) *	1995-03-21	2002-04-10	应用研究系统Ars股份公司	人绒毛膜促性腺激素液体制剂
PL187400B1 (pl) *	1996-02-20	2004-06-30	Applied Research Systems	Białka hybrydowe tworzące heterodimery
IT1287138B1 (it) *	1996-11-07	1998-08-04	Ibsa Inst Biochimique Sa	Procedimento per la separazione e purificazione di fsh e lh
AU8142198A (en)	1997-06-12	1998-12-30	Regents Of The University Of California, The	A transcription factor coactivator protein, p/cip
EP0998486B2 (en) *	1997-06-13	2012-02-01	Genentech, Inc.	Protein recovery by chromatography followed by filtration upon a charged layer
US6583109B1 (en) *	1997-06-24	2003-06-24	Robert C. Gallo	Therapeutic polypeptides from β-hCG and derivatives
EE05644B1 (et) *	2000-02-22	2013-04-15	Applied Research Systems Ars Holding N.V.	Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

2001
- 2001-01-22 EE EEP200200469A patent/EE05644B1/xx unknown
- 2001-01-22 EP EP01901188A patent/EP1257564B1/en not_active Expired - Lifetime
- 2001-01-22 AU AU26804/01A patent/AU783320B2/en not_active Expired
- 2001-01-22 WO PCT/EP2001/000665 patent/WO2001062773A1/en not_active Ceased
- 2001-01-22 SI SI200130858T patent/SI1257564T1/sl unknown
- 2001-01-22 RS YUP-602/02A patent/RS50741B/sr unknown
- 2001-01-22 HU HU0204231A patent/HU228935B1/hu unknown
- 2001-01-22 BR BRPI0108556A patent/BRPI0108556B8/pt not_active IP Right Cessation
- 2001-01-22 CA CA002399020A patent/CA2399020A1/en not_active Abandoned
- 2001-01-22 PL PL357508A patent/PL205149B1/pl unknown
- 2001-01-22 DE DE60135541T patent/DE60135541D1/de not_active Expired - Lifetime
- 2001-01-22 US US10/204,630 patent/US7297777B2/en not_active Expired - Lifetime
- 2001-01-22 HU HUP1300063 patent/HU1300063D0/hu unknown
- 2001-01-22 JP JP2001562554A patent/JP4588960B2/ja not_active Expired - Lifetime
- 2001-01-22 UA UA2002086890A patent/UA78488C2/uk unknown
- 2001-01-22 SK SK1206-2002A patent/SK287146B6/sk not_active IP Right Cessation
- 2001-01-22 EP EP06024050A patent/EP1752466A3/en not_active Withdrawn
- 2001-01-22 MX MXPA02007871A patent/MXPA02007871A/es active IP Right Grant
- 2001-01-22 EA EA200200892A patent/EA006605B1/ru not_active IP Right Cessation
- 2001-01-22 KR KR1020027010625A patent/KR100806911B1/ko not_active Expired - Lifetime
- 2001-01-22 IL IL15130801A patent/IL151308A0/xx unknown
- 2001-01-22 CN CNB018053637A patent/CN100482679C/zh not_active Expired - Lifetime
- 2001-01-22 DK DK01901188T patent/DK1257564T3/da active
- 2001-01-22 AT AT01901188T patent/ATE406378T1/de active
- 2001-01-22 ME MEP-2008-389A patent/ME00296B/me unknown
- 2001-01-22 PT PT01901188T patent/PT1257564E/pt unknown
- 2001-01-22 CZ CZ20022855A patent/CZ303144B6/cs not_active IP Right Cessation
- 2001-01-22 ES ES01901188T patent/ES2307585T3/es not_active Expired - Lifetime
- 2001-01-22 UA UAA200511832A patent/UA86938C2/uk unknown
- 2001-01-22 HR HR20020650A patent/HRP20020650B1/xx not_active IP Right Cessation
2002
- 2002-07-31 ZA ZA200206109A patent/ZA200206109B/en unknown
- 2002-08-14 BG BG107000A patent/BG65807B1/bg unknown
- 2002-08-18 IL IL151308A patent/IL151308A/en active IP Right Grant
- 2002-08-21 NO NO20023985A patent/NO328694B1/no not_active IP Right Cessation
2006
- 2006-01-06 AU AU2006200059A patent/AU2006200059A1/en not_active Abandoned
2007
- 2007-08-28 US US11/846,118 patent/US20070299001A1/en not_active Abandoned
2008
- 2008-10-27 CY CY20081101218T patent/CY1108460T1/el unknown

Also Published As

Publication number	Publication date
JP4588960B2 (ja)	2010-12-01
HU1300063D0 (hu)	2003-03-28
NO20023985D0 (no)	2002-08-21
SK287146B6 (sk)	2010-01-07
HRP20020650A2 (en)	2004-12-31
EA006605B1 (ru)	2006-02-24
BG65807B1 (bg)	2009-12-31
US20070299001A1 (en)	2007-12-27
UA78488C2 (en)	2007-04-10
SI1257564T1 (sl)	2008-12-31
EP1752466A3 (en)	2012-10-10
EP1752466A2 (en)	2007-02-14
YU60202A (sh)	2005-09-19
ES2307585T3 (es)	2008-12-01
AU2680401A (en)	2001-09-03
HRP20020650B1 (en)	2011-02-28
MXPA02007871A (es)	2003-02-10
NO20023985L (no)	2002-08-21
HU228935B1 (en)	2013-06-28
PL357508A1 (en)	2004-07-26
EE200200469A (et)	2004-04-15
HUP0204231A3 (en)	2005-09-28
CN100482679C (zh)	2009-04-29
HK1052016A1 (zh)	2003-08-29
CZ303144B6 (cs)	2012-05-02
AU2006200059A1 (en)	2006-02-02
CY1108460T1 (el)	2014-04-09
DK1257564T3 (da)	2008-10-06
PL205149B1 (pl)	2010-03-31
BRPI0108556B1 (pt)	2015-04-14
RS50741B (sr)	2010-08-31
ME00296B (me)	2011-05-10
SK12062002A3 (sk)	2002-12-03
US20030104553A1 (en)	2003-06-05
UA86938C2 (uk)	2009-06-10
CZ20022855A3 (cs)	2002-11-13
WO2001062773A1 (en)	2001-08-30
HUP0204231A2 (hu)	2003-03-28
DE60135541D1 (de)	2008-10-09
BR0108556A (pt)	2003-01-28
AU783320B2 (en)	2005-10-13
PT1257564E (pt)	2008-09-10
IL151308A0 (en)	2003-04-10
ZA200206109B (en)	2003-07-31
CN1404485A (zh)	2003-03-19
IL151308A (en)	2009-11-18
ATE406378T1 (de)	2008-09-15
CA2399020A1 (en)	2001-08-30
BG107000A (en)	2003-04-30
NO328694B1 (no)	2010-04-26
EA200200892A1 (ru)	2003-02-27
MEP38908A (en)	2011-02-10
EP1257564A1 (en)	2002-11-20
KR100806911B1 (ko)	2008-02-22
US7297777B2 (en)	2007-11-20
BRPI0108556B8 (pt)	2021-05-25
KR20030001359A (ko)	2003-01-06
EP1257564B1 (en)	2008-08-27
JP2003524015A (ja)	2003-08-12

Publication	Publication Date	Title
EE200200469A (et)	2004-04-15	Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG
EE200200464A (et)	2003-12-15	Meetod LH puhastamiseks
PL366364A1 (en)	2005-01-24	Process for producing peptides by using in vitrotranscription/translation system
CY1107666T1 (el)	2013-04-18	Διαδικασια για την παρασκευη συνθεσεων γοναδοτροπινης
FI913058A0 (fi)	1991-06-20	Foerfarande foer behandling av blaoscancerceller.
BR9301641A (pt)	1993-10-26	Processo para produzir uma preparacao de fator viii,altamente purificada e uso
ES2161790T3 (es)	2001-12-16	Procedimiento de separacion y de purificacion de proteinas dependientes de la vitamina k.
EP0301314A3 (en)	1990-05-30	A method for the purification of interferon
Hearn et al.	1979	The Analysis of Insulin-Related Peptides by Reversed-Phase High-Performance Liquid Chromatography
WOMEN	2002	Human chorionic gonadotropine (hCG) is used as a medicinein several diseases like infertility of men and women. This hormone is excreted by urine. At the present time, isolation of hCG from urine is the only way for preparation of this hormone. The highest concentration of hCG in urine and serum is in the early second trimester of pregnancy.

Legal Events

Date	Code	Title	Description
2007-10-15	GB1A	Change in the ownership or in the address of the owner
2012-04-16	HC1A	Change of owner name