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EE05432B1 - Prroloprimidiinid kui valgukinaasi inhibiitorid - Google Patents

Prroloprimidiinid kui valgukinaasi inhibiitorid

Info

Publication number
EE05432B1
EE05432B1 EEP200400003A EEP200400003A EE05432B1 EE 05432 B1 EE05432 B1 EE 05432B1 EE P200400003 A EEP200400003 A EE P200400003A EE P200400003 A EEP200400003 A EE P200400003A EE 05432 B1 EE05432 B1 EE 05432B1
Authority
EE
Estonia
Prior art keywords
rrolop
rimidines
protein kinase
kinase inhibitors
inhibitors
Prior art date
Application number
EEP200400003A
Other languages
English (en)
Inventor
Joseph Cox Paul
Nadeem Majid Tahir
Amendola Shelley
Daniele Deprets Stephanie
Edlin Chris
Leslie Pedgrift Brian
Halley Frank
Edwards Michael
Baudoin Bernard
Mcfarlane Mclay Lain
John Aldous David
Original Assignee
Aventis Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.
Publication of EE200400003A publication Critical patent/EE200400003A/et
Publication of EE05432B1 publication Critical patent/EE05432B1/et

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EEP200400003A 2001-06-23 2002-06-21 Prroloprimidiinid kui valgukinaasi inhibiitorid EE05432B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0115393.1A GB0115393D0 (en) 2001-06-23 2001-06-23 Chemical compounds
US30167801P 2001-06-28 2001-06-28
PCT/GB2002/002835 WO2003000695A1 (en) 2001-06-23 2002-06-21 Pyrrolopyrimidines as protein kinase inhibitors

Publications (2)

Publication Number Publication Date
EE200400003A EE200400003A (et) 2004-02-16
EE05432B1 true EE05432B1 (et) 2011-06-15

Family

ID=9917225

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200400003A EE05432B1 (et) 2001-06-23 2002-06-21 Prroloprimidiinid kui valgukinaasi inhibiitorid

Country Status (22)

Country Link
EP (1) EP1404676A1 (et)
JP (1) JP4344607B2 (et)
CN (1) CN1294135C (et)
AU (1) AU2002314325B8 (et)
BR (1) BR0210652A (et)
CA (1) CA2451932C (et)
CZ (1) CZ20033443A3 (et)
EA (1) EA007415B1 (et)
EC (1) ECSP034922A (et)
EE (1) EE05432B1 (et)
GB (1) GB0115393D0 (et)
HU (1) HUP0400300A3 (et)
ME (1) MEP19308A (et)
NZ (1) NZ529766A (et)
OA (1) OA12632A (et)
PL (1) PL374096A1 (et)
RS (1) RS51698B (et)
SK (1) SK15882003A3 (et)
TN (1) TNSN03144A1 (et)
TR (1) TR200302242T2 (et)
UA (1) UA76760C2 (et)
WO (1) WO2003000695A1 (et)

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US7550598B2 (en) 2004-08-18 2009-06-23 Takeda Pharmaceutical Company Limited Kinase inhibitors
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EP1812439B2 (en) 2004-10-15 2017-12-06 Takeda Pharmaceutical Company Limited Kinase inhibitors
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TW201313721A (zh) 2011-08-18 2013-04-01 Incyte Corp 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
WO2013157022A1 (en) 2012-04-20 2013-10-24 Advinus Therapeutics Limited Substituted hetero-bicyclic compounds, compositions and medicinal applications thereof
AR091079A1 (es) 2012-05-18 2014-12-30 Incyte Corp Derivados de pirrolopirimidina y pirrolopiridina sustituida con piperidinilciclobutilo como inhibidores de jak
HRP20161530T1 (hr) 2012-07-26 2017-02-10 Glaxo Group Limited 2-(azaindol-2-il)benzimidazoli kao pad4 inhibitori
MX2015002887A (es) 2012-09-06 2015-07-06 Plexxikon Inc Compuestos y metodos para la modulacion de cinasas, e indicaciones para ello.
PL2919766T3 (pl) 2012-11-15 2021-10-04 Incyte Holdings Corporation Postacie dawkowania ruksolitynibu o przedłużonym uwalnianiu
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Also Published As

Publication number Publication date
JP4344607B2 (ja) 2009-10-14
WO2003000695A1 (en) 2003-01-03
EP1404676A1 (en) 2004-04-07
UA76760C2 (uk) 2006-09-15
CN1294135C (zh) 2007-01-10
EA007415B1 (ru) 2006-10-27
TR200302242T2 (tr) 2004-12-21
BR0210652A (pt) 2004-08-10
NZ529766A (en) 2008-11-28
JP2005508300A (ja) 2005-03-31
WO2003000695A8 (en) 2004-03-11
ECSP034922A (es) 2004-04-28
OA12632A (en) 2006-06-14
CA2451932C (en) 2009-12-29
CA2451932A1 (en) 2003-01-03
RS51698B (sr) 2011-10-31
PL374096A1 (en) 2005-09-19
MEP19308A (en) 2010-06-10
HUP0400300A2 (en) 2007-08-28
RS99203A (sr) 2006-12-15
SK15882003A3 (sk) 2004-07-07
CZ20033443A3 (en) 2004-03-17
CN1518552A (zh) 2004-08-04
AU2002314325B2 (en) 2009-01-08
AU2002314325B8 (en) 2009-01-29
GB0115393D0 (en) 2001-08-15
TNSN03144A1 (en) 2005-12-23
EA200400073A1 (ru) 2004-08-26
EE200400003A (et) 2004-02-16
HUP0400300A3 (en) 2010-12-28

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