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EE04041B1 - Nimesuliidi geelsüsteemid paikseks kasutamiseks - Google Patents

Nimesuliidi geelsüsteemid paikseks kasutamiseks

Info

Publication number
EE04041B1
EE04041B1 EEP199900355A EEP9900355A EE04041B1 EE 04041 B1 EE04041 B1 EE 04041B1 EE P199900355 A EEP199900355 A EE P199900355A EE P9900355 A EEP9900355 A EE P9900355A EE 04041 B1 EE04041 B1 EE 04041B1
Authority
EE
Estonia
Prior art keywords
nimesulite
topical use
gel systems
gel
formulations
Prior art date
Application number
EEP199900355A
Other languages
English (en)
Estonian (et)
Inventor
Bader Stefano
H�usermann Enrique
Monti Tiziana
Original Assignee
Helsinn Healthcare S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinn Healthcare S.A. filed Critical Helsinn Healthcare S.A.
Publication of EE9900355A publication Critical patent/EE9900355A/xx
Publication of EE04041B1 publication Critical patent/EE04041B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
EEP199900355A 1997-02-25 1998-02-20 Nimesuliidi geelsüsteemid paikseks kasutamiseks EE04041B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI000408A IT1289973B1 (it) 1997-02-25 1997-02-25 Sistemi gelificati di nimesulide per uso topico
PCT/EP1998/000990 WO1998037879A1 (en) 1997-02-25 1998-02-20 Nimesulide gel systems for topical use

Publications (2)

Publication Number Publication Date
EE9900355A EE9900355A (et) 2000-02-15
EE04041B1 true EE04041B1 (et) 2003-06-16

Family

ID=11376173

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP199900355A EE04041B1 (et) 1997-02-25 1998-02-20 Nimesuliidi geelsüsteemid paikseks kasutamiseks

Country Status (32)

Country Link
US (2) US20020119997A1 (zh)
EP (1) EP0971708B1 (zh)
JP (1) JP2001513093A (zh)
KR (1) KR100413143B1 (zh)
CN (1) CN1148174C (zh)
AT (1) ATE210437T1 (zh)
AU (1) AU723843B2 (zh)
BG (1) BG64664B1 (zh)
BR (1) BR9807729A (zh)
CA (1) CA2279277A1 (zh)
CU (1) CU22836A3 (zh)
CZ (1) CZ293665B6 (zh)
DE (2) DE69802913T2 (zh)
DK (1) DK0971708T3 (zh)
EE (1) EE04041B1 (zh)
ES (1) ES2169506T3 (zh)
GE (1) GEP20022628B (zh)
HU (1) HU226122B1 (zh)
ID (1) ID22668A (zh)
IL (1) IL131128A (zh)
IS (1) IS2090B (zh)
IT (1) IT1289973B1 (zh)
MX (1) MXPA99007468A (zh)
NO (1) NO994040L (zh)
PL (1) PL190603B1 (zh)
PT (1) PT971708E (zh)
RS (1) RS49700B (zh)
RU (1) RU2181285C2 (zh)
SK (1) SK284809B6 (zh)
TR (1) TR199902034T2 (zh)
UA (1) UA50807C2 (zh)
WO (1) WO1998037879A1 (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU718356B2 (en) * 1998-01-12 2000-04-13 Panacea Biotec Limited A parenteral water-miscible non-intensely coloured injectable composition of non-steroidal anit-inflammatory drugs
GB2340751B (en) * 1998-08-12 2003-11-05 Edko Trading Representation Pharmaceutical compositions
AU1888900A (en) * 1999-05-31 2000-12-18 Shashikant Prabhudas Kurani A novel formulation of n-(4-nitro-2-phenoxyphenyl)methanesulfonamide
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
DE60143360D1 (de) 2000-08-03 2010-12-09 Antares Pharma Ipl Ag Zusammensetzung zur transdermalen und/oder transmukosalen Verabreichung von Wirkstoffen, die ausreichende therapeutische Spiegel garantiert
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
ES2222817B1 (es) * 2003-07-25 2007-03-01 Luis Ucelay Sanz Gel frio.
MXPA06003316A (es) 2003-10-10 2006-06-08 Antares Pharma Ipl Ag Formulacion farmaceutica transdermica para minimizar los residuos en la piel.
US7425340B2 (en) 2004-05-07 2008-09-16 Antares Pharma Ipl Ag Permeation enhancing compositions for anticholinergic agents
WO2007124250A2 (en) 2006-04-21 2007-11-01 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
US8067399B2 (en) 2005-05-27 2011-11-29 Antares Pharma Ipl Ag Method and apparatus for transdermal or transmucosal application of testosterone
TR200906775A1 (tr) * 2009-09-02 2011-03-21 Sanovel İlaç San.Ve Ti̇c.A.Ş. Nimesulid ve kas gevşetici kombinasyonları
CN102068404A (zh) * 2009-11-25 2011-05-25 中国人民武装警察部队医学院 一种尼美舒利温度敏感水凝胶及其制备方法
WO2016116909A2 (en) * 2015-01-23 2016-07-28 Dr. Reddy's Laboratories Limited Non-staining topical gel compositions of nimesulide
RU2593777C1 (ru) * 2015-04-20 2016-08-10 Общество с ограниченной ответственностью "Трейдсервис" Гелевая форма нимесулида, обладающая противовоспалительным и анальгетическим действием
CN108158993A (zh) * 2018-01-12 2018-06-15 连云港本草美汇医药科技有限公司 一种祛痘控油微乳凝胶剂及其制备方法与应用
WO2022066803A1 (en) 2020-09-22 2022-03-31 Alphyn Biologics, Llc Topical croton lechleri compositions and their use in the treatment of a bacterial colonization or primary or secondary bacterial infection of an underlying skin disorder
JP2024508454A (ja) 2021-02-25 2024-02-27 アルフィン バイオロジックス、エルエルシー 局所皮膚細菌性皮膚疾患治療用組成物
PL244577B1 (pl) 2021-12-16 2024-02-12 Univ Gdanski Sole nimesulidu i sposób otrzymywania kryształów soli nimesulidu
PL444224A1 (pl) 2023-03-28 2024-09-30 Uniwersytet Gdański Sól potasowa nimesulidu oraz sposób otrzymywania kryształów soli potasowych nimesulidu

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1251838B (it) * 1991-09-20 1995-05-26 Lpb Ist Farm Uso della nimesulide nel trattamento della cataratta
BE1008307A3 (fr) * 1994-06-16 1996-04-02 Europharmaceuticals Sa Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation.
DE782855T1 (de) * 1994-10-05 1998-05-28 Helsinn Healthcare Sa Antiinflammatorische wirkstoffe zur aüsserlichen anwendung
HUP9601442A3 (en) * 1995-07-25 1999-03-29 Panacea Biotec Ltd Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them
CZ288398B6 (en) * 1995-10-05 2001-06-13 Helsinn Healthcare Sa Pharmaceutical preparation exhibiting antiphlogistic activity
HUP9601443A3 (en) * 1996-05-29 1999-03-29 Panacea Biotec Ltd Injectable analgetic pharmaceutical compositions for intramuscular use containing nimesulid, and process for producing them
IT1291278B1 (it) * 1996-07-05 1999-01-07 Errekappa Euroterapici S P A Preparazione farmaceutica a base di nimesulide per uso topico

Also Published As

Publication number Publication date
CA2279277A1 (en) 1998-09-03
CZ298699A3 (cs) 2000-02-16
EP0971708B1 (en) 2001-12-12
SK284809B6 (sk) 2005-11-03
RS49700B (sr) 2007-12-31
HUP0001486A3 (en) 2002-11-28
ITMI970408A1 (it) 1998-08-25
IS2090B (is) 2006-03-15
ATE210437T1 (de) 2001-12-15
IL131128A (en) 2003-11-23
TR199902034T2 (xx) 1999-11-22
AU6499298A (en) 1998-09-18
NO994040D0 (no) 1999-08-20
MXPA99007468A (es) 2004-05-05
US7186755B2 (en) 2007-03-06
KR20000075561A (ko) 2000-12-15
IL131128A0 (en) 2001-01-28
IT1289973B1 (it) 1998-10-19
US20020119997A1 (en) 2002-08-29
KR100413143B1 (ko) 2003-12-31
ES2169506T3 (es) 2002-07-01
DK0971708T3 (da) 2002-03-25
ID22668A (id) 1999-12-02
GEP20022628B (en) 2002-02-25
EP0971708A1 (en) 2000-01-19
YU38599A (sh) 2002-06-19
DE69802913T2 (de) 2002-07-04
JP2001513093A (ja) 2001-08-28
HUP0001486A2 (hu) 2000-10-28
SK114199A3 (en) 2000-11-07
US20030036563A1 (en) 2003-02-20
PL335141A1 (en) 2000-04-10
UA50807C2 (uk) 2002-11-15
RU2181285C2 (ru) 2002-04-20
AU723843B2 (en) 2000-09-07
CN1148174C (zh) 2004-05-05
EE9900355A (et) 2000-02-15
CN1248165A (zh) 2000-03-22
CU22836A3 (es) 2003-01-29
DE971708T1 (de) 2000-08-17
WO1998037879A1 (en) 1998-09-03
PL190603B1 (pl) 2005-12-30
HK1025265A1 (zh) 2000-11-10
BG103645A (en) 2000-04-28
IS5143A (is) 1999-07-30
PT971708E (pt) 2002-05-31
BG64664B1 (bg) 2005-11-30
DE69802913D1 (de) 2002-01-24
HU226122B1 (en) 2008-04-28
BR9807729A (pt) 2000-02-15
CZ293665B6 (cs) 2004-06-16
NO994040L (no) 1999-10-20

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Legal Events

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KB4A Valid patent at the end of a year

Effective date: 20031231

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Effective date: 20051231

KB4A Valid patent at the end of a year

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Effective date: 20071231

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Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20091231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20110220