EE03285B1 - Immuunsust stimuleerivad monoklonaalsed antikehad - Google Patents

Immuunsust stimuleerivad monoklonaalsed antikehad

Info

Publication number: EE03285B1
Authority: EE; Estonia
Prior art keywords: stimulated; immunity; monoclonal antibodies; tumor; elicts
Prior art date: 1994-01-31

Application number

EE9600107A

Other languages

English (en)

Estonian (et)

Inventor

Hardy Britta

Novogrodsky Avraham

Original Assignee

Mor Research Applications Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-31

Filing date

1995-01-30

Publication date

2000-08-15

1995-01-30 Application filed by Mor Research Applications Ltd. filed Critical Mor Research Applications Ltd.

2000-08-15 Publication of EE03285B1 publication Critical patent/EE03285B1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cell Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Zoology (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Detergent Compositions (AREA)

EE9600107A 1994-01-31 1995-01-30 Immuunsust stimuleerivad monoklonaalsed antikehad EE03285B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IL10850194A IL108501A (en)	1994-01-31	1994-01-31	Antibodies and pharmaceutical compositions containing them
PCT/US1995/001137 WO1995020605A1 (en)	1994-01-31	1995-01-30	Immuno-stimulatory monoclonal antibodies

Publications (1)

Publication Number	Publication Date
EE03285B1 true EE03285B1 (et)	2000-08-15

Family

ID=11065761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9600107A EE03285B1 (et)	1994-01-31	1995-01-30	Immuunsust stimuleerivad monoklonaalsed antikehad

Country Status (20)

Country	Link
US (1)	US5897862A (lt)
EP (1)	EP0742795B1 (lt)
JP (1)	JP3478398B2 (lt)
CN (1)	CN1052733C (lt)
AT (1)	ATE171461T1 (lt)
AU (1)	AU693526B2 (lt)
CA (1)	CA2182289C (lt)
DE (1)	DE69504955T2 (lt)
DK (1)	DK0742795T3 (lt)
EE (1)	EE03285B1 (lt)
ES (1)	ES2124533T3 (lt)
FI (1)	FI963004L (lt)
IL (1)	IL108501A (lt)
LT (1)	LT4225B (lt)
LV (1)	LV11624B (lt)
MD (1)	MD1374G2 (lt)
MX (1)	MX9603080A (lt)
NO (1)	NO317020B1 (lt)
RU (1)	RU2155190C2 (lt)
WO (1)	WO1995020605A1 (lt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2145634C1 (ru) *	1998-03-12	2000-02-20	Булычева Татьяна Ивановна	Штамм культивируемых клеток мышиной гибридомы, используемый для получения моноклональных антител к ядрышковому антигену, ассоциированному с клеточной пролиферацией
IL129299A0 (en) *	1999-03-31	2000-02-17	Mor Research Applic Ltd	Monoclonal antibodies antigens and diagnosis of malignant diseases
RU2192888C1 (ru) *	2001-02-15	2002-11-20	Эпштейн Олег Ильич	Лекарственное средство и способ лечения патологического синдрома
CN1294148C (zh) *	2001-04-11	2007-01-10	中国科学院遗传与发育生物学研究所	环状单链三特异抗体
IL145926A0 (en)	2001-10-15	2002-07-25	Mor Research Applic Ltd	Peptide epitopes of mimotopes useful in immunomodulation
IL149820A0 (en)	2002-05-23	2002-11-10	Curetech Ltd	Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
WO2004004771A1 (ja)	2002-07-03	2004-01-15	Ono Pharmaceutical Co., Ltd.	免疫賦活組成物
DE10311248A1 (de) *	2003-03-14	2004-09-30	Müller-Hermelink, Hans Konrad, Prof. Dr.	Humaner monoklonaler Antikörper
RU2404993C2 (ru) *	2003-07-02	2010-11-27	Иннейт Фарма	Композиции и способы регуляции клеточной активности nk
WO2006021955A2 (en) *	2004-08-23	2006-03-02	Mor Research Applications Ltd.	Use of bat monoclonal antibody for immunotherapy
EP2439273B1 (en) *	2005-05-09	2019-02-27	Ono Pharmaceutical Co., Ltd.	Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
HRP20151102T1 (xx)	2005-07-01	2015-11-20	E. R. Squibb & Sons, L.L.C.	Humana monoklonska antitijela za ligand programirane smrti 1 (pd-l1)
PT2170959E (pt) *	2007-06-18	2014-01-07	Merck Sharp & Dohme	Anticorpos para o receptor humano de morte programada pd-1
ES2639857T3 (es) *	2008-02-11	2017-10-30	Cure Tech Ltd.	Anticuerpos monoclonales para el tratamiento del tumor
MD3972C2 (ro) *	2009-03-11	2010-07-31	Ион МЕРЕУЦЭ	Remediu şi metodă de tratament al stărilor precanceroase
EP2734551B1 (en)	2011-07-24	2018-01-10	Cure Tech Ltd.	Variants of humanized immunomodulatory monoclonal antibodies
WO2015048312A1 (en)	2013-09-26	2015-04-02	Costim Pharmaceuticals Inc.	Methods for treating hematologic cancers
US9580504B1 (en)	2013-11-07	2017-02-28	Curetech Ltd.	Pidilizumab monoclonal antibody therapy following stem cell transplantation
JOP20200094A1 (ar)	2014-01-24	2017-06-16	Dana Farber Cancer Inst Inc	جزيئات جسم مضاد لـ pd-1 واستخداماتها
JOP20200096A1 (ar)	2014-01-31	2017-06-16	Children’S Medical Center Corp	جزيئات جسم مضاد لـ tim-3 واستخداماتها
RS59853B1 (sr)	2014-03-14	2020-02-28	Novartis Ag	Molekuli anti-lag-3 antitela i njihove upotrebe
TWI693232B (zh)	2014-06-26	2020-05-11	美商宏觀基因股份有限公司	與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
KR20170060042A (ko)	2014-09-13	2017-05-31	노파르티스 아게	Alk 억제제의 조합 요법
TWI773646B (zh)	2015-06-08	2022-08-11	美商宏觀基因股份有限公司	結合lag-3的分子和其使用方法
CR20200423A (es)	2015-07-30	2021-01-20	Macrogenics Inc	Moléculas de unión a pd-1 y métodos de uso de las mismas (divisional 2018-0062)
WO2017040790A1 (en)	2015-09-01	2017-03-09	Agenus Inc.	Anti-pd-1 antibodies and methods of use thereof
HK1251158A1 (zh)	2015-09-29	2019-01-25	细胞基因公司	Pd-1结合蛋白及其使用方法
EP3370768B9 (en)	2015-11-03	2022-03-16	Janssen Biotech, Inc.	Antibodies specifically binding pd-1 and their uses
BR112018011781A2 (en)	2015-12-14	2018-12-04	Macrogenics, Inc.	bispecific molecule having one or more epitope binding sites capable of immunospecific binding to (one) pd-1 epitope (s) and one or more epitope binding sites capable of immunospecific binding to (one) epitope (s) -4, and pharmaceutical composition
EP3471754A1 (en)	2016-06-20	2019-04-24	Kymab Limited	Anti-pd-l1 antibodies
KR102257154B1 (ko)	2016-09-19	2021-05-28	셀진 코포레이션	Pd-1 결합 단백질을 사용하는 면역 질환의 치료 방법
US10766958B2 (en)	2016-09-19	2020-09-08	Celgene Corporation	Methods of treating vitiligo using PD-1 binding antibodies
KR102603681B1 (ko)	2016-12-07	2023-11-17	아게누스 인코포레이티드	항체 및 이의 사용방법
US12398209B2 (en)	2018-01-22	2025-08-26	Janssen Biotech, Inc.	Methods of treating cancers with antagonistic anti-PD-1 antibodies
GB202107994D0 (en)	2021-06-04	2021-07-21	Kymab Ltd	Treatment of cancer
KR20250140097A (ko)	2023-01-30	2025-09-24	키맵 리미티드	항체

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5182368A (en) *	1986-06-13	1993-01-26	Ledbetter Jeffrey A	Ligands and methods for augmenting B-cell proliferation

1994
- 1994-01-31 IL IL10850194A patent/IL108501A/en not_active IP Right Cessation
1995
- 1995-01-30 DE DE69504955T patent/DE69504955T2/de not_active Expired - Lifetime
- 1995-01-30 AT AT95910891T patent/ATE171461T1/de active
- 1995-01-30 JP JP52021095A patent/JP3478398B2/ja not_active Expired - Lifetime
- 1995-01-30 AU AU18686/95A patent/AU693526B2/en not_active Expired
- 1995-01-30 WO PCT/US1995/001137 patent/WO1995020605A1/en not_active Ceased
- 1995-01-30 CA CA002182289A patent/CA2182289C/en not_active Expired - Lifetime
- 1995-01-30 DK DK95910891T patent/DK0742795T3/da active
- 1995-01-30 ES ES95910891T patent/ES2124533T3/es not_active Expired - Lifetime
- 1995-01-30 EP EP95910891A patent/EP0742795B1/en not_active Expired - Lifetime
- 1995-01-30 CN CN95192406A patent/CN1052733C/zh not_active Expired - Lifetime
- 1995-01-30 EE EE9600107A patent/EE03285B1/xx unknown
- 1995-01-30 US US08/380,857 patent/US5897862A/en not_active Expired - Lifetime
- 1995-01-30 MD MD96-0296A patent/MD1374G2/ro unknown
- 1995-01-30 RU RU96116984/13A patent/RU2155190C2/ru active
- 1995-01-30 FI FI963004A patent/FI963004L/fi unknown
1996
- 1996-07-29 MX MX9603080A patent/MX9603080A/es not_active IP Right Cessation
- 1996-07-29 NO NO19963168A patent/NO317020B1/no not_active IP Right Cessation
- 1996-07-30 LT LT96-115A patent/LT4225B/lt not_active IP Right Cessation
- 1996-09-06 LV LVP-96-317A patent/LV11624B/en unknown

Also Published As

Publication number	Publication date
FI963004A0 (fi)	1996-07-29
CA2182289C (en)	2003-10-21
EP0742795B1 (en)	1998-09-23
JP3478398B2 (ja)	2003-12-15
ES2124533T3 (es)	1999-02-01
LV11624A (en)	1996-12-20
MD1374F2 (en)	1999-12-31
AU693526B2 (en)	1998-07-02
NO963168D0 (no)	1996-07-29
IL108501A0 (en)	1994-05-30
MD1374G2 (ro)	2000-09-30
CN1052733C (zh)	2000-05-24
US5897862A (en)	1999-04-27
JPH09508390A (ja)	1997-08-26
FI963004A7 (fi)	1996-09-27
LT4225B (en)	1997-10-27
RU2155190C2 (ru)	2000-08-27
LT96115A (en)	1997-05-26
AU1868695A (en)	1995-08-15
DK0742795T3 (da)	1999-06-14
WO1995020605A1 (en)	1995-08-03
NO963168L (no)	1996-09-27
CA2182289A1 (en)	1995-08-03
IL108501A (en)	1998-10-30
LV11624B (en)	1997-06-20
DE69504955D1 (de)	1998-10-29
NO317020B1 (no)	2004-07-26
MX9603080A (es)	1998-01-31
EP0742795A1 (en)	1996-11-20
CN1145077A (zh)	1997-03-12
FI963004L (fi)	1996-09-27
ATE171461T1 (de)	1998-10-15
DE69504955T2 (de)	1999-05-27

Publication	Publication Date	Title
EE03285B1 (et)	2000-08-15	Immuunsust stimuleerivad monoklonaalsed antikehad
FI864037A7 (fi)	1987-04-08	Monoklonaaliset vasta-aineet ihmisen rintasyöpää vastaan.
DE69319662D1 (de)	1998-08-20	Monoklonale Antikörper gegen GP130-Protein
NL300387I1 (nl)	2009-07-01	Antilichaam tegen menselijke interleukine-6-receptor
EP0636029A4 (en)	1996-10-09	AGAINST CARCINOMA-ASSOCIATED ANTIQUE ANTIBODIES.
ZA946767B (en)	1995-04-03	Monocional antibodies having property of causing apoptosis.
ATE71411T1 (de)	1992-01-15	Monoklonale antikoerper mit spezifitaet fuer membran-assoziierte antigene.
IT8622630A0 (it)	1986-12-10	Anticorpi monoclonali crossreattivi e cross-protettivi contro sierotipi di p. aeruginosa.
MY107079A (en)	1995-09-30	Method of reducing immunoglobulin e responses
IT1207589B (it)	1989-05-25	Composizione di anticorpi monoclonali umani cross-protettivi.
DE3586216D1 (de)	1992-07-23	Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
NZ305083A (en)	1999-06-29	Use of cd40 binding proteins (a cd40 ligand or monoclonal antibody that specifically binds to cd40) for stimulating a immune response
DE3884646D1 (de)	1993-11-11	Humanes Karcinom-assoziertes Antigen und an dieses Antigen bindende Antikörper.
DE3854999D1 (de)	1996-03-21	An karzinoma assoziierte antigene und antikörper, die diese antigene erkennen
DK69690D0 (da)	1990-03-16	Humane anti-rh(d) monoklonale antistoffer
FI92716C (fi)	1994-12-27	Uudet monoklonaaliset vasta-aineet IFN-omegalle, niiden valmistusmenetelmät ja niiden käyttö IFN-omegan puhdistamiseen ja osoittamiseen
DE3580482D1 (de)	1990-12-13	Monoklonale antikoerper und immunisierung damit.
DK717888A (da)	1989-06-25	Monoklonale antistoffer
DE3850993D1 (de)	1994-09-15	Monoklonaler Antikörper spezifisch gegen humane Pankreas-Phospholipase-A2.
DE3785795D1 (de)	1993-06-17	Monoklonale anti-menschliche magenkrebs-antikoerper.
DK49291D0 (da)	1991-03-19	Gramnegativ-bakterieendotoxinblokerende, monoklonale antistoffer
EP0585364A4 (en)	1994-11-02	THE ANTIQUE CTAA 81AV78 RECOGNIZED BY THE MONOCLONAL HUMAN ANTIBODY 81AV78.
DE3687542D1 (de)	1993-03-04	Monoklonaler antikoerper gegen humanes protein c.
DK413389A (da)	1990-02-25	Monoklonale antistoffer
FI924278A0 (fi)	1992-09-24	Bcrf1 antagonister foer skoetsel av epstein-barr-virusinfektioner.