EE03121B1 - 4-(4'-tert-butüülfenüül)-1-(4'-karboksüfenoksü)-2-butanooli modifikatsioon II, selle valmistamismeetod ja nimetatud modifikatsiooni sisaldav farmatseutiline preparaat - Google Patents
4-(4'-tert-butüülfenüül)-1-(4'-karboksüfenoksü)-2-butanooli modifikatsioon II, selle valmistamismeetod ja nimetatud modifikatsiooni sisaldav farmatseutiline preparaatInfo
- Publication number
- EE03121B1 EE03121B1 EE9400219A EE9400219A EE03121B1 EE 03121 B1 EE03121 B1 EE 03121B1 EE 9400219 A EE9400219 A EE 9400219A EE 9400219 A EE9400219 A EE 9400219A EE 03121 B1 EE03121 B1 EE 03121B1
- Authority
- EE
- Estonia
- Prior art keywords
- modification
- carboxyphenoxy
- butylphenyl
- butanol
- tert
- Prior art date
Links
- 230000004048 modification Effects 0.000 title abstract 5
- 238000012986 modification Methods 0.000 title abstract 5
- LNXBEIZREVRNTF-UHFFFAOYSA-N Lifibrol Chemical compound C1=CC(C(C)(C)C)=CC=C1CCC(O)COC1=CC=C(C(O)=O)C=C1 LNXBEIZREVRNTF-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 229950000716 lifibrol Drugs 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000002329 infrared spectrum Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4314175A DE4314175C2 (de) | 1993-04-29 | 1993-04-29 | Modifikation II von Lifibrol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE03121B1 true EE03121B1 (et) | 1998-10-15 |
Family
ID=6486761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EE9400219A EE03121B1 (et) | 1993-04-29 | 1994-11-18 | 4-(4'-tert-butüülfenüül)-1-(4'-karboksüfenoksü)-2-butanooli modifikatsioon II, selle valmistamismeetod ja nimetatud modifikatsiooni sisaldav farmatseutiline preparaat |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5493051A (et) |
| EP (1) | EP0622351B1 (et) |
| JP (1) | JPH06340527A (et) |
| CN (1) | CN1045083C (et) |
| AT (1) | ATE154586T1 (et) |
| AU (1) | AU667260B2 (et) |
| CA (1) | CA2122193A1 (et) |
| DE (2) | DE4314175C2 (et) |
| DK (1) | DK0622351T3 (et) |
| EE (1) | EE03121B1 (et) |
| ES (1) | ES2102714T3 (et) |
| GR (1) | GR3024579T3 (et) |
| SI (1) | SI0622351T1 (et) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5140958A (en) * | 1990-06-27 | 1992-08-25 | Toyota Jidosha Kabushiki Kaisha | Two-stroke engine |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3326164A1 (de) * | 1983-07-20 | 1985-01-31 | Klinge Pharma GmbH, 8000 München | Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE4032037A1 (de) * | 1990-10-09 | 1992-04-16 | Klinge Co Chem Pharm Fab | Neue p-oxibenzoesaeurederivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE4119055A1 (de) * | 1991-06-10 | 1992-12-17 | Klinge Co Chem Pharm Fab | Verfahren zur herstellung der reinen enantiomere des lifibrol und seiner alkylester |
-
1993
- 1993-04-29 DE DE4314175A patent/DE4314175C2/de not_active Expired - Fee Related
-
1994
- 1994-03-22 DE DE69403854T patent/DE69403854T2/de not_active Expired - Fee Related
- 1994-03-22 EP EP94104512A patent/EP0622351B1/en not_active Expired - Lifetime
- 1994-03-22 ES ES94104512T patent/ES2102714T3/es not_active Expired - Lifetime
- 1994-03-22 AT AT94104512T patent/ATE154586T1/de active
- 1994-03-22 SI SI9430076T patent/SI0622351T1/xx unknown
- 1994-03-22 DK DK94104512.2T patent/DK0622351T3/da active
- 1994-03-28 AU AU59086/94A patent/AU667260B2/en not_active Ceased
- 1994-04-26 CA CA002122193A patent/CA2122193A1/en not_active Abandoned
- 1994-04-28 JP JP6091366A patent/JPH06340527A/ja active Pending
- 1994-04-28 CN CN94104925A patent/CN1045083C/zh not_active Expired - Fee Related
- 1994-04-29 US US08/235,525 patent/US5493051A/en not_active Expired - Fee Related
- 1994-11-18 EE EE9400219A patent/EE03121B1/et unknown
-
1997
- 1997-08-29 GR GR970402221T patent/GR3024579T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0622351B1 (en) | 1997-06-18 |
| GR3024579T3 (en) | 1997-12-31 |
| AU5908694A (en) | 1994-11-03 |
| DK0622351T3 (da) | 1997-07-07 |
| DE4314175C2 (de) | 1995-03-30 |
| CA2122193A1 (en) | 1994-10-30 |
| CN1104203A (zh) | 1995-06-28 |
| SI0622351T1 (en) | 1997-12-31 |
| EP0622351A1 (en) | 1994-11-02 |
| CN1045083C (zh) | 1999-09-15 |
| DE69403854T2 (de) | 1997-11-27 |
| DE69403854D1 (de) | 1997-07-24 |
| US5493051A (en) | 1996-02-20 |
| JPH06340527A (ja) | 1994-12-13 |
| ATE154586T1 (de) | 1997-07-15 |
| DE4314175A1 (de) | 1994-11-03 |
| ES2102714T3 (es) | 1997-08-01 |
| AU667260B2 (en) | 1996-03-14 |
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