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EE03997B1 - Albuterooli doseeriv inhalaator - Google Patents

Albuterooli doseeriv inhalaator

Info

Publication number
EE03997B1
EE03997B1 EE9700280A EE9700280A EE03997B1 EE 03997 B1 EE03997 B1 EE 03997B1 EE 9700280 A EE9700280 A EE 9700280A EE 9700280 A EE9700280 A EE 9700280A EE 03997 B1 EE03997 B1 EE 03997B1
Authority
EE
Estonia
Prior art keywords
albuterol
metered dose
dose inhaler
inhaler
metered
Prior art date
Application number
EE9700280A
Other languages
English (en)
Other versions
EE9700280A (et
Inventor
Loy Britto Ignatius
Original Assignee
Glaxo Wellcome Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27025574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03997(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Wellcome Inc. filed Critical Glaxo Wellcome Inc.
Publication of EE9700280A publication Critical patent/EE9700280A/et
Publication of EE03997B1 publication Critical patent/EE03997B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/44Valves specially adapted for the discharge of contents; Regulating devices
    • B65D83/52Metering valves; Metering devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0222Materials for reducing friction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Laminated Bodies (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EE9700280A 1995-04-14 1996-04-10 Albuterooli doseeriv inhalaator EE03997B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42237195A 1995-04-14 1995-04-14
US58486096A 1996-01-05 1996-01-05
PCT/US1996/005002 WO1996032099A1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for albuterol

Publications (2)

Publication Number Publication Date
EE9700280A EE9700280A (et) 1998-04-15
EE03997B1 true EE03997B1 (et) 2003-04-15

Family

ID=27025574

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700280A EE03997B1 (et) 1995-04-14 1996-04-10 Albuterooli doseeriv inhalaator

Country Status (32)

Country Link
US (2) US6131566A (et)
EP (3) EP0820279B1 (et)
JP (1) JPH11509433A (et)
KR (1) KR100496836B1 (et)
CN (1) CN1217654C (et)
AP (1) AP791A (et)
AT (2) ATE219934T1 (et)
AU (1) AU710382B2 (et)
BG (1) BG64075B1 (et)
BR (1) BR9604976A (et)
CA (3) CA2217950C (et)
CY (1) CY2402B1 (et)
CZ (1) CZ292578B6 (et)
DE (2) DE69622166T2 (et)
DK (1) DK0820279T3 (et)
EA (1) EA000890B1 (et)
EE (1) EE03997B1 (et)
ES (2) ES2292526T3 (et)
GE (1) GEP20002254B (et)
HU (1) HU219900B (et)
IS (1) IS4577A (et)
NO (1) NO316588B1 (et)
NZ (1) NZ306278A (et)
OA (1) OA10627A (et)
PL (1) PL180900B1 (et)
PT (1) PT820279E (et)
RO (1) RO119118B1 (et)
SI (1) SI0820279T1 (et)
SK (1) SK281746B6 (et)
TR (1) TR199701167T1 (et)
UA (1) UA50734C2 (et)
WO (1) WO1996032099A1 (et)

Families Citing this family (180)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1547636A1 (en) * 1995-04-14 2005-06-29 SmithKline Beecham Corporation Metered dose inhaler for salmeterol
CA2217950C (en) * 1995-04-14 2001-12-25 Glaxo Wellcome Inc. Metered dose inhaler for albuterol
CA2218179A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for beclomethasone dipropionate
ES2276736T3 (es) * 1995-04-14 2007-07-01 Smithkline Beecham Corporation Inhalador medidor de dosis para propionato de flucticasona.
GB9526392D0 (en) 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
TW533865U (en) * 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2338951B (en) * 1997-09-03 2000-06-21 Bespak Plc Improvements in or relating to metering valves for pressuriseddispensing containers
US20030103906A1 (en) * 1997-10-14 2003-06-05 Smithkline Beecham Corporation Metered dose inhaler having internal surfaces coated with fluorocarbon polymer
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
DE69901813T3 (de) 1998-02-23 2008-08-28 Glaxo Group Ltd., Greenford Unter Druck gesetzte Spenderbehälter
GB9814717D0 (en) * 1998-02-23 1998-09-02 Bespak Plc Improvements in drug delivery devices
GB9805938D0 (en) * 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
DK1102579T3 (da) * 1998-08-04 2003-07-14 Jago Res Ag Medicinske aerosolformuleringer
GB2340759B (en) * 1998-08-26 2003-05-07 Bespak Plc Improvements in drug delivery devices
GB9820937D0 (en) * 1998-09-26 1998-11-18 Glaxo Group Ltd Inhalation device
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
IT1303788B1 (it) * 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
US6315112B1 (en) 1998-12-18 2001-11-13 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6390291B1 (en) 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6352152B1 (en) 1998-12-18 2002-03-05 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
GB9918573D0 (en) 1999-08-07 1999-10-06 Glaxo Group Ltd Valve
PE20010720A1 (es) * 1999-12-11 2001-07-26 Glaxo Group Ltd Distribuidor de medicamento
EP1235606A1 (en) * 1999-12-11 2002-09-04 Glaxo Group Limited Medicament dispenser
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
US7089934B2 (en) 2000-02-28 2006-08-15 Vectura Limited Delivery of oral drugs
JP2003525090A (ja) * 2000-03-01 2003-08-26 グラクソ グループ リミテッド 定量噴霧式吸入器
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
UA73986C2 (uk) * 2000-05-22 2005-10-17 К'Єзі Фармачеутічі С.П.А. АЕРОЗОЛЬНА КОМПОЗИЦІЯ, ЩО МІСТИТЬ <font face="Symbol">b</font>2-АДРЕНЕРГІЧНИЙ АГОНІСТ ТРИВАЛОЇ ДІЇ, ДОЗУЮЧИЙ ІНГАЛЯТОР ПІД ТИСКОМ ТА СПОСІБ ЙОГО ЗАПОВНЕННЯ
GB0015043D0 (en) 2000-06-21 2000-08-09 Glaxo Group Ltd Medicament dispenser
AU2001270074A1 (en) 2000-06-22 2002-01-02 Glaxo Group Limited Method and package for storing a pressurized container containing a drug
GB0021024D0 (en) * 2000-08-29 2000-10-11 Glaxo Group Ltd Inhalation device
US20030207057A1 (en) * 2000-09-18 2003-11-06 Britto Ignatius Loy Metered dose inhaler can coated two or more times with fluorocarbon polymers
GB2367756B (en) 2000-10-12 2003-01-08 Bespak Plc Dispensing apparatus
US7247704B2 (en) * 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease
HU229899B1 (en) * 2000-12-22 2014-12-29 Glaxo Group Ltd Brentford Metered dose inhaler for salmeterol xinafoate
EP1241113A1 (en) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein
GB0106046D0 (en) * 2001-03-12 2001-05-02 Glaxo Group Ltd Canister
US6455028B1 (en) 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
GB2375098B (en) 2001-04-30 2003-08-27 Bespak Plc Improvements in valves for pressurised dispensing containers
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
DE60103527T2 (de) 2001-07-02 2005-06-16 Chiesi Farmaceutici S.P.A. Optimierte Tobramycin-Formulierung zur Aerosolbildung
GB2377694A (en) * 2001-07-17 2003-01-22 Bespak Plc Dispensing apparatus
US7767872B2 (en) * 2001-09-06 2010-08-03 Mpg Biotechnologies, Llc Thimerosal removal device
US8440791B2 (en) * 2001-09-06 2013-05-14 Mgp Biotechnologies, Llc Thimerosal removal device
GB0122725D0 (en) * 2001-09-21 2001-11-14 Glaxo Group Ltd Drug dispensing components
GB0130703D0 (en) * 2001-12-21 2002-02-06 Glaxo Group Ltd Particles
GB2384190A (en) * 2002-01-22 2003-07-23 Bespak Plc Dispensing device for a powdered product
AU2003205860A1 (en) 2002-02-13 2003-09-04 Glaxo Group Limited Carboxylic acid compounds for use as surfactants
ATE465712T1 (de) * 2002-03-01 2010-05-15 Chiesi Farma Spa Ultrafeine zusammensetzungen von formoterol
GB0205327D0 (en) 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
GB0207906D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
GB0207899D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and cielesonide aerosol formulations
US6830046B2 (en) 2002-04-29 2004-12-14 Hewlett-Packard Development Company, L.P. Metered dose inhaler
US20070139442A1 (en) * 2002-09-13 2007-06-21 Robinson Karl E Coated blending system
US20030051727A1 (en) * 2002-11-04 2003-03-20 Haan Richard J Aerosol mdi overcap containing desiccant
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
CA2507572C (en) 2002-12-10 2011-04-19 Sepracor Inc. Levalbuterol salt
EP1575648A4 (en) * 2002-12-18 2007-07-04 Glaxo Group Ltd DRUG DELIVERY SYSTEM WITH A VENTILATED MOUTHPIECE
WO2004104493A2 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Methods of controlling uniformity of substrate temperature and self-contained heating unit and drug-supply unit employing same
JP4607112B2 (ja) 2003-08-11 2011-01-05 グラクソ グループ リミテッド 医薬定量噴霧式吸入器及び前記吸引器に関連する方法
US20050172958A1 (en) * 2003-08-20 2005-08-11 The Brigham And Women's Hospital, Inc. Inhalation device and system for the remote monitoring of drug administration
ES2668780T3 (es) 2003-08-29 2018-05-22 Glaxo Group Limited Inhalador de dosificación farmacéutica medida y procedimientos relacionados con el mismo
US20070053843A1 (en) * 2003-10-28 2007-03-08 Dawson Michelle L Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
US7481213B2 (en) * 2004-02-11 2009-01-27 Hewlett-Packard Development Company, L.P. Medicament dispenser
US7467630B2 (en) * 2004-02-11 2008-12-23 Hewlett-Packard Development Company, L.P. Medicament dispenser
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
IL177103A0 (en) * 2004-02-27 2006-12-10 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurized metered dose inhalers
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
CA2576961A1 (en) 2004-08-12 2006-03-02 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
GB0418045D0 (en) 2004-08-12 2004-09-15 Glaxo Group Ltd Compounds
ES2417491T3 (es) * 2004-12-17 2013-08-08 Glenmark Pharmaceuticals S.A. Novedosos compuestos heterocíclicos útiles para el tratamiento de trastornos inflamatorios y alérgicos
AR066386A1 (es) * 2004-12-17 2009-08-19 Glenmark Pharmaceuticals Sa Compuestos heterociclicos condensados, metodos e intermediarios para su preparacion, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por la inhibicion de la pde-4
US9365905B2 (en) 2005-02-10 2016-06-14 Dmv-Fonterra Excipients Technology Gmbh Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
WO2006086130A2 (en) * 2005-02-10 2006-08-17 Glaxo Group Limited Process for crystallizing lactose particles for use in pharmaceutical formulations
RU2008108476A (ru) * 2005-08-08 2009-09-20 Новартис АГ (CH) Изолированная емкость для дозирующих ингаляторов
US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
BRPI0710240A2 (pt) 2006-04-20 2011-08-09 Glaxo Group Ltd composto, uso de um composto, método para o tratamento de um paciente humano ou animal com uma condição ou doença, composição farmacêutica, combinação, e, processo para a preparação de um composto
US20070272768A1 (en) * 2006-05-26 2007-11-29 Williams Donald R Water-Based Airless Adhesive Application Container
GB0611587D0 (en) 2006-06-12 2006-07-19 Glaxo Group Ltd Novel compounds
US20070286814A1 (en) * 2006-06-12 2007-12-13 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
WO2008112353A2 (en) * 2007-02-05 2008-09-18 The Brigham And Women's Hospital, Inc. Instrumented metered-dose inhaler and methods for predicting disease exacerbations
JP5825757B2 (ja) 2007-02-11 2015-12-02 マップ・ファーマシューティカルズ・インコーポレイテッド 副作用プロファイルを最小限にしながら片頭痛の迅速な緩和を可能にするdheの治療上の投与方法
EP2121088B1 (en) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
WO2009006137A1 (en) * 2007-07-03 2009-01-08 Glaxo Group Limited Aerosol canister employing a polymeric film having improved moisture barrier properties
EP2205302A4 (en) 2007-11-06 2010-12-29 3M Innovative Properties Co MEDICAL INHALATION DEVICES AND COMPONENTS THEREOF
GB0721739D0 (en) 2007-11-06 2007-12-19 3M Innovative Properties Co medicinal inhalation devices and components thereof
GB0721737D0 (en) 2007-11-06 2007-12-19 3M Innovative Properties Co Medicinal inhalation devices and components thereof
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US8163743B2 (en) 2008-06-05 2012-04-24 GlaxoGroupLimited 4-carboxamide indazole derivatives useful as inhibitors of PI3-kinases
WO2009147190A1 (en) 2008-06-05 2009-12-10 Glaxo Group Limited Novel compounds
GB2467758A (en) * 2009-02-12 2010-08-18 Consort Medical Plc Metered dose inhaler with internal coating of siloxane and/or silazane
US8524751B2 (en) 2009-03-09 2013-09-03 GlaxoSmithKline Intellecutual Property Development 4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases
US8354539B2 (en) 2009-03-10 2013-01-15 Glaxo Group Limited Indole derivatives as IKK2 inhibitors
JP2012520845A (ja) 2009-03-17 2012-09-10 グラクソ グループ リミテッド Itk阻害剤として使用されるピリミジン誘導体
WO2010107958A1 (en) 2009-03-19 2010-09-23 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 6 (STAT6) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP2408915A2 (en) 2009-03-19 2012-01-25 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF GATA BINDING PROTEIN 3 (GATA3) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
JP2012520683A (ja) 2009-03-19 2012-09-10 メルク・シャープ・エンド・ドーム・コーポレイション 低分子干渉核酸(siNA)を用いた結合組織増殖因子(CTGF)遺伝子発現のRNA干渉媒介性阻害
AU2010226604A1 (en) 2009-03-19 2011-10-13 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of BTB and CNC homology 1, basic leucine zipper transcription factor 1 (Bach 1) gene expression using short interfering nucleic acid (siNA) sequence listing
EP2411019A2 (en) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1 (STAT1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2010111468A2 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF THE NERVE GROWTH FACTOR BETA CHAIN (NGFß) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA)
EP2411517A2 (en) 2009-03-27 2012-02-01 Merck Sharp&Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF THE INTERCELLULAR ADHESION MOLECULE 1 (ICAM-1)GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2010111490A2 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF THE THYMIC STROMAL LYMPHOPOIETIN (TSLP) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2010111464A1 (en) 2009-03-27 2010-09-30 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
ES2876933T3 (es) 2009-04-30 2021-11-15 Glaxo Group Ltd Indazoles sustituidos con oxazol como inhibidores de PI3-cinasas
EP2427278B1 (en) 2009-05-06 2015-09-23 3M Innovative Properties Company Medicinal inhalation devices and components thereof
US10410838B2 (en) 2009-05-06 2019-09-10 3M Innovative Properties Company Apparatus and method for plasma treatment of containers
EP2427591A1 (en) 2009-05-06 2012-03-14 3M Innovative Properties Company Medicinal inhalation device
WO2010133294A2 (de) 2009-05-18 2010-11-25 Boehringer Ingelheim International Gmbh Adapter, inhalationseinrichtung und zerstäuber
US20110070555A1 (en) * 2009-09-21 2011-03-24 Garrison Dental Solutions Matrix band for dental applications
PH12012500631A1 (en) 2009-09-29 2012-11-12 Glaxo Group Ltd Improvements to pressurised metered dose inhalers
GB0918150D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
MX2012005711A (es) 2009-11-17 2012-10-05 Cipla Ltd Soluciones de inhalacion.
US10016568B2 (en) * 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504051B1 (en) 2009-11-25 2019-09-04 Boehringer Ingelheim International GmbH Nebulizer
JP5715640B2 (ja) 2009-11-25 2015-05-13 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
JP2013512879A (ja) 2009-12-03 2013-04-18 グラクソ グループ リミテッド Pi3キナーゼの阻害剤としてのベンズピラゾール誘導体
JP2013512880A (ja) 2009-12-03 2013-04-18 グラクソ グループ リミテッド Pi3−キナーゼ阻害剤としてのインダゾール誘導体
EP2507226A1 (en) 2009-12-03 2012-10-10 Glaxo Group Limited Novel compounds
WO2011110575A1 (en) 2010-03-11 2011-09-15 Glaxo Group Limited Derivatives of 2-[2-(benzo- or pyrido-) thiazolylamino]-6-aminopyridine, useful in the treatment of respiratoric, allergic or inflammatory diseases
WO2011160932A1 (en) 2010-06-24 2011-12-29 Boehringer Ingelheim International Gmbh Nebulizer
EP2601293B1 (en) 2010-08-02 2017-12-06 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2012024170A2 (en) 2010-08-17 2012-02-23 Merck Sharp & Dohme Corp. RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
US9233997B2 (en) 2010-08-26 2016-01-12 Sirna Therapeutics, Inc. RNA interference mediated inhibition of prolyl hydroxylase domain 2 (PHD2) gene expression using short interfering nucleic acid (siNA)
SI2614058T1 (sl) 2010-09-08 2015-10-30 Glaxosmithkline Intellectual Property Development Limited Polimorfi in soli N-(5-(4-(5-(((2R,6S)-2,6-dimetil-4-morfolinil)metil)-1,3-oksazol-2-il)- 1H-indazol-6-il)-2-(metiloksi)-3-piridinil)metansulfonamida
US9326987B2 (en) 2010-09-08 2016-05-03 Glaxo Group Limited Indazole derivatives for use in the treatment of influenza virus infection
WO2012035055A1 (en) 2010-09-17 2012-03-22 Glaxo Group Limited Novel compounds
GB201018124D0 (en) 2010-10-27 2010-12-08 Glaxo Group Ltd Polymorphs and salts
EP3766975A1 (en) 2010-10-29 2021-01-20 Sirna Therapeutics, Inc. Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
USD666097S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666493S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666096S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666099S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666098S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666492S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
KR20140129120A (ko) 2012-02-06 2014-11-06 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 기침 치료용 pi3k 저해제
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
EP3919620A1 (en) 2012-05-02 2021-12-08 Sirna Therapeutics, Inc. Short interfering nucleic acid (sina) compositions
CA2879341C (en) 2012-07-26 2019-06-11 Glaxo Group Limited 2- (azaindol-2-yl) benzimidazoles as pad4 inhibitors
RU2015122218A (ru) 2012-11-30 2017-01-10 Ф. Хоффманн-Ля Рош Аг Ингибиторы тирозинкиназы брутона
US9884886B2 (en) 2012-12-06 2018-02-06 Merck Sharp & Dohme Disulfide masked prodrug compositions and methods
WO2015018904A1 (en) 2013-08-09 2015-02-12 Boehringer Ingelheim International Gmbh Nebulizer
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
AU2014321420B2 (en) 2013-09-22 2017-06-15 Sunshine Lake Pharma Co., Ltd. Substituted aminopyrimidine compounds and methods of use
KR20160062178A (ko) 2013-10-17 2016-06-01 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 호흡기 질병의 치료를 위한 pi3k 억제제
AU2014336250A1 (en) 2013-10-17 2016-04-14 Glaxosmithkline Intellectual Property Development Limited PI3K inhibitor for treatment of respiratory disease
BR112016023983B1 (pt) 2014-05-07 2022-10-18 Boehringer Ingelheim International Gmbh Contentor para um nebulizador, nebulizador para um fluido e método para conectar um contentor a um dispositivo indicador
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
KR102730574B1 (ko) 2014-05-07 2024-11-15 베링거 인겔하임 인터내셔날 게엠베하 분무기, 표시 디바이스 및 컨테이너
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
PT3236967T (pt) 2014-12-22 2020-01-06 Suda Pharmaceuticals Ltd Prevenção e tratamento de doença metastática em pacientes com cancro trombocitóticos
US10407407B2 (en) 2015-05-21 2019-09-10 Glaxosmithkline Intellectual Property Development Limited Benzoimidazole derivatives as PAD4 inhibitors
CN108348470A (zh) 2015-11-18 2018-07-31 葛兰素史克知识产权第二有限公司 利巴韦林的药物组合物
GB201602527D0 (en) 2016-02-12 2016-03-30 Glaxosmithkline Ip Dev Ltd Chemical compounds
WO2018029126A1 (en) 2016-08-08 2018-02-15 Glaxosmithkline Intellectual Property Development Limited Chemical compounds
WO2018149472A1 (en) 2017-02-14 2018-08-23 Presspart Gmbh & Co. Kg Method for sealingly joining a canister and a top cover
GB201706102D0 (en) 2017-04-18 2017-05-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
GB201712081D0 (en) 2017-07-27 2017-09-13 Glaxosmithkline Ip Dev Ltd Chemical compounds
GB201717996D0 (en) * 2017-10-31 2017-12-13 Portal Medical Ltd Medicament dispenser device
US11649238B2 (en) 2018-01-17 2023-05-16 Glaxosmithkline Intellectual Property Development Limited Substituted pyrazolo[1,5-a]pyrimidines as PI4K inhibitors
KR102737185B1 (ko) 2018-01-20 2024-12-05 선샤인 레이크 파르마 컴퍼니 리미티드 치환된 아미노피리미딘 화합물 및 이의 사용 방법
WO2019152873A1 (en) 2018-02-02 2019-08-08 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device
AU2019285374A1 (en) * 2018-06-13 2021-01-28 Puff-Ah Pty Ltd Apparatus for use in delivering respiratory drugs
CN110840864B (zh) * 2019-12-20 2022-02-22 广州健康元呼吸药物工程技术有限公司 一种β2受体激动剂吸入气雾剂及包含该吸入气雾剂的产品
US12514995B2 (en) 2021-02-15 2026-01-06 Glenmark Pharmaceuticals Limited Metered dose inhalers of fluticasone or an ester thereof
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject

Family Cites Families (118)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2562118A (en) * 1950-02-09 1951-07-24 Du Pont Polytetrafluoroethylene coating compositions
US2968427A (en) * 1955-06-28 1961-01-17 Meshberg Philip Valve for aerosol container
CA598388A (en) * 1954-09-20 1960-05-24 Meshberg Philip Aerosol containers and valves therefor
GB878409A (en) * 1957-03-26 1961-09-27 United Drug And Chemical Compa Improvements in or relating to dispensing devices
US2886217A (en) * 1957-05-20 1959-05-12 Riker Laboratories Inc Dispensing device
US2892576A (en) * 1957-11-14 1959-06-30 Lawrence T Ward Metering button valve assembly
US2980301A (en) * 1958-09-02 1961-04-18 Riker Laboratories Inc Metering valve for aerosol container
GB864392A (en) * 1958-11-10 1961-04-06 Rexall Drug Company Ltd Improvements in or relating to dispensing devices for aerosols
US3506737A (en) * 1965-10-23 1970-04-14 Owens Illinois Inc Glass aerosol bottles and method for making same
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
GB1191700A (en) * 1967-02-27 1970-05-13 Ekco Prod Inc Coated Metalware
FR1584784A (et) * 1968-08-13 1970-01-02
BE755555A (fr) 1969-09-02 1971-03-01 Richardson Merrell Inc Derives de quinoxaline
FR2082593A5 (en) * 1970-03-20 1971-12-10 Oreal Aerosol can prodn
US3739950A (en) * 1971-04-05 1973-06-19 J Gorman Aerosol inhalation apparatus
NO134730L (et) 1971-07-19 1900-01-01
LU63737A1 (et) * 1971-08-17 1972-01-04
US3896602A (en) * 1971-09-15 1975-07-29 Tor H Petterson Method of manufacturing of a barrier package
US4087026A (en) * 1971-09-15 1978-05-02 Petterson Tor H Barrier package
FR2159593A5 (fr) * 1971-11-04 1973-06-22 Skm Sa Installation de peinture par pulverisation
US4143204A (en) * 1971-12-27 1979-03-06 E. I. Du Pont De Nemours And Company Articles coated with fluorocarbon resins
DE2227142A1 (de) * 1972-06-03 1973-12-13 Pampus Kg Rohre und behaelter aus glasfaserverstaerktem kunststoff und einer auskleidung, zum beispiel aus ptfe
US3962171A (en) * 1973-03-02 1976-06-08 Mcgarry & Waters Composition for protecting surfaces
US3929537A (en) * 1973-07-19 1975-12-30 Austral Erwin Engineering Co Preparation of plastic-metal laminates
GB1426342A (en) * 1973-11-19 1976-02-25 Ici Ltd Coating compositions
FR2267496A1 (en) 1974-04-11 1975-11-07 Sidel Sa Method of sealing valve on aerosol container - uses internally ribbed sleeve over ribbed valve and sleeve
US4180609A (en) * 1975-07-11 1979-12-25 E. I. Du Pont De Nemours And Company Article coated with fluoropolymer finish with improved scratch resistance
US4167605A (en) * 1975-07-29 1979-09-11 Imperial Chemical Industries Limited Article with antistick coating and composition
DE2738382A1 (de) * 1976-08-26 1978-03-02 Union Carbide Corp Verbesserter kunststoffbehaelter und verfahren zu seiner herstellung
GB2003415A (en) * 1977-09-02 1979-03-14 American Can Co Improvements relating to the manufacture of containers
US4125152A (en) * 1977-09-19 1978-11-14 Borg-Warner Corporation Scale resistant heat transfer surfaces and a method for their preparation
JPS5920547B2 (ja) * 1979-07-04 1984-05-14 東洋製罐株式会社 溶接缶
DE2947025A1 (de) * 1979-11-22 1981-06-04 Glyco-Metall-Werke Daelen & Loos Gmbh, 6200 Wiesbaden Zwei- oder mehrschicht-verbundwerkstoff
ZA807387B (en) * 1979-12-08 1981-11-25 Metal Box Co Ltd Containers
JPS56138200A (en) * 1980-02-15 1981-10-28 Glaxo Group Ltd Androstane carbothioate compound
GB2077229B (en) * 1980-05-16 1983-08-03 Neotechnic Eng Ltd Valve assembly for a pressurized aerosoldispensing container
GB2105189B (en) 1981-07-24 1985-03-20 Fisons Plc Inhalation drugs
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
NZ212911A (en) * 1984-07-31 1988-06-30 Glaxo Group Ltd Aerosol dispensing device; actuator lever acts when cover in open position
DE3677811D1 (de) * 1985-04-19 1991-04-11 Nippon Steel Corp Buechse und verfahren zur herstellung von buechsen.
NL8501767A (nl) * 1985-06-19 1987-01-16 Euro Technical Oilservices Bv Inrichting voor het behandelen van een verontreinigingen bevattende vloeistof.
DE3778727D1 (de) * 1986-02-27 1992-06-11 Nippon Kokan Kk Grundbeschichtete metallplatte.
JPS6312445A (ja) * 1986-06-24 1988-01-19 東洋製罐株式会社 イ−ジイオ−プン蓋付缶体及びその製法
US5536583A (en) * 1986-07-01 1996-07-16 Edlon Products, Inc. Polymer metal bonded composite and method of producing same
US4897439A (en) * 1986-07-01 1990-01-30 Edlon Products, Inc. Polymer-metal bonded composite and method of producing same
EP0260084B1 (en) * 1986-09-08 1992-12-30 Asia Can Company Limited Metal container and method of manufacturing the same
US4819834A (en) * 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
EP0327777A1 (fr) 1988-02-12 1989-08-16 S.A. DES ETABLISSEMENTS STAUBLI (France) Capteur de déplacement pour machines automatiques
GB2205297B (en) * 1987-06-05 1991-06-19 Lin Pac Mouldings A container assembly
BR8807106A (pt) * 1987-06-26 1989-10-31 Werding Winfried J Dispositivo para armazenagens e fornecimento controlado de produtos que se encontram sob pressao
DE8709978U1 (de) * 1987-07-21 1987-10-08 A. u. K. Müller GmbH & Co KG, 4000 Düsseldorf Elektromagnetventil, insbesondere Auslaufventil für Brühwasser
GB8724243D0 (en) * 1987-10-15 1987-11-18 Metal Box Plc Laminates of polyolefin-based film
GB8724242D0 (en) * 1987-10-15 1987-11-18 Metal Box Plc Laminated metal sheet
IT1223451B (it) * 1987-11-24 1990-09-19 Coster Tecnologie Speciali Spa Procedimento per ottenere fondelli metallici protetti per valvole per aerosol e simili
GB2214891A (en) * 1988-02-05 1989-09-13 Fibrenyle Ltd Containers for pressurized material
JP2562343B2 (ja) * 1988-02-23 1996-12-11 北海製罐株式会社 エアゾール容器及びエアゾール製品
EP0338670B1 (en) * 1988-03-22 1994-05-11 FISONS plc Pharmaceutical Compositions
FI94342C (fi) 1988-03-29 1995-08-25 Ciba Geigy Ag Menetelmä uusien alkanofenonien valmistamiseksi
JPH0289633A (ja) * 1988-05-20 1990-03-29 Sumitomo Electric Ind Ltd フッ素樹脂被覆物
US4961966A (en) * 1988-05-25 1990-10-09 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Fluorocarbon coating method
US4902318A (en) * 1988-05-25 1990-02-20 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Inlet apparatus for gas-aerosol sampling
JPH0267374A (ja) * 1988-08-31 1990-03-07 Takeuchi Press Ind Co Ltd エアゾール缶容器
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8903629D0 (en) * 1989-02-17 1989-04-05 Metal Box Plc Metal/polymer laminates
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5006383A (en) * 1989-06-28 1991-04-09 The Dow Chemical Company Polymeric blend and laminated structures prepared therefrom
FR2650219B1 (fr) * 1989-07-06 1991-10-04 Pechiney Rhenalu Procede d'obtention de materiaux multicouches aptes a etre transformes par emboutissage ou emboutissage-etirage en corps creux
FR2649359B1 (fr) * 1989-07-06 1993-02-12 Cebal Bande ou portion de bande pour emboutissage ou emboutissage-etirage, et son utilisation
JP2600387B2 (ja) * 1989-09-06 1997-04-16 東洋紡績株式会社 金属貼合せ用ポリエステルフィルム
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
GB8921222D0 (en) * 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
US5345980A (en) 1989-09-21 1994-09-13 Glaxo Group Limited Method and apparatus an aerosol container
JPH03199699A (ja) * 1989-12-27 1991-08-30 Ntn Corp ターボ分子ポンプ
GB9000984D0 (en) * 1990-01-16 1990-03-14 Hoechst U K Limited Polymers D Aerosol container
US5043191A (en) * 1990-02-27 1991-08-27 Miles Inc. Method of protecting hard surfaces
DE4009397A1 (de) * 1990-03-23 1991-09-26 Weidenhammer Packungen Dosenartige verpackung fuer fliessfaehige produkte
AU614234B1 (en) * 1990-06-28 1991-08-22 Kabushiki Gaisha Tokai Vessel for aerosol
GB9015522D0 (en) * 1990-07-13 1990-08-29 Braithwaite Philip W Inhaler
DE4023909A1 (de) * 1990-07-27 1992-01-30 Wild Rudolf Gmbh & Co Wiederverwendbarer behaelter aus kunststoff sowie seine herstellung und verwendung
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
EP0487200B1 (en) * 1990-11-14 2000-06-21 Titeflex Corporation Fluoropolymer aluminium laminate
BR9107221A (pt) * 1990-12-12 1993-11-16 Du Pont Sistema de revestimento nao aderente com ptfe de viscosidades de fusao diferentes para gradiente de concentracao
BR9107220A (pt) * 1990-12-12 1993-11-03 Du Pont Sistema de revestimento nao-aderente com ptfe e pfa ou fep para gradiente de concentracao
US5168107A (en) * 1990-12-12 1992-12-01 E. I. Du Pont De Nemours And Company Non-stick coating system with PTFE of two low melt viscosities for concentration gradient
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
US5290539A (en) * 1990-12-21 1994-03-01 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
EP0499142A3 (en) 1991-02-09 1993-05-05 Hoechst Aktiengesellschaft Potentiation of the antireactive-antiasthmatic effect of inhaled loop diuretics by inhaled non steroidal anti-flammatory drugs
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
RU2027448C1 (ru) 1991-04-25 1995-01-27 Государственное предприятие "ВЭЛТ" Ингалятор
JPH089215B2 (ja) * 1991-05-30 1996-01-31 新日本製鐵株式会社 容器用樹脂複合鋼板の製造方法
RU2008939C1 (ru) 1991-06-10 1994-03-15 Вячеслав Николаевич Поздняков Физиотерапевтический ингалятор
RU2012362C1 (ru) 1991-06-24 1994-05-15 Юрий Алексеевич Волгин Ингалятор
DE4124730C3 (de) * 1991-07-25 2001-09-06 Ahc Oberflaechentechnik Gmbh Anodisierte Gegenstände aus Aluminium oder Magnesium mit in die Oxidschicht eingelagerten Fluorpolymeren und Verfahren zu deren Herstellung
ATE128350T1 (de) * 1991-12-12 1995-10-15 Glaxo Group Ltd Pharmazeutische aerosolformulierung.
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
US5202110A (en) * 1992-01-22 1993-04-13 Virginia Commonwealth University Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants
US5261538A (en) * 1992-04-21 1993-11-16 Glaxo Inc. Aerosol testing method
EP0609453B1 (en) * 1992-06-25 2002-10-23 Denso Corporation Mobile object identification device
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
JP2863389B2 (ja) * 1992-11-13 1999-03-03 三菱樹脂株式会社 エアゾール缶用容器及びエアゾール缶
DE69324161T2 (de) * 1992-12-09 1999-10-28 Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield Stabilisierte medizinische aerosollösungen
GB9306292D0 (en) 1993-03-26 1993-05-19 Glaxo Group Ltd Method
US5437267A (en) * 1993-08-03 1995-08-01 Weinstein; Allan Device for delivering aerosol to the nasal membranes and method of use
US6596260B1 (en) * 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
US5468798A (en) * 1994-02-18 1995-11-21 Whitford Corporation Basecoat for a coating system
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
US5597433A (en) * 1994-05-27 1997-01-28 Panoramic, Inc. Method and apparatus for manufacturing plastic canisters
EP1547636A1 (en) * 1995-04-14 2005-06-29 SmithKline Beecham Corporation Metered dose inhaler for salmeterol
CA2217950C (en) * 1995-04-14 2001-12-25 Glaxo Wellcome Inc. Metered dose inhaler for albuterol
ES2276736T3 (es) * 1995-04-14 2007-07-01 Smithkline Beecham Corporation Inhalador medidor de dosis para propionato de flucticasona.
US5674592A (en) * 1995-05-04 1997-10-07 Minnesota Mining And Manufacturing Company Functionalized nanostructured films
JP3199699B2 (ja) 1999-04-14 2001-08-20 核燃料サイクル開発機構 弁座面の平坦度測定装置

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NO316588B1 (no) 2004-03-01
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CA2361954A1 (en) 1996-10-17
WO1996032099A1 (en) 1996-10-17
AU710382B2 (en) 1999-09-16
HUP9801526A2 (hu) 1998-10-28
DK0820279T3 (da) 2002-10-07
UA50734C2 (uk) 2002-11-15
SK138897A3 (en) 1998-05-06
NO974737D0 (no) 1997-10-13
CA2361954C (en) 2003-07-08
ATE219934T1 (de) 2002-07-15
EP0820279B1 (en) 2002-07-03
DE69637257D1 (de) 2007-10-31
GEP20002254B (en) 2000-10-25
CA2217950C (en) 2001-12-25
PT820279E (pt) 2002-11-29
ATE373613T1 (de) 2007-10-15
CZ325997A3 (cs) 1998-03-18
EA000890B1 (ru) 2000-06-26
EP1157749A3 (en) 2003-11-26
NO974737L (no) 1997-12-11
TR199701167T1 (xx) 1998-03-21
IS4577A (is) 1997-10-03
KR100496836B1 (ko) 2005-10-21
KR19980703847A (ko) 1998-12-05
CZ292578B6 (cs) 2003-10-15
EP1870122A2 (en) 2007-12-26
HK1009398A1 (en) 1999-09-17
AP791A (en) 1999-12-17
JPH11509433A (ja) 1999-08-24
EP1157749A2 (en) 2001-11-28
BG64075B1 (bg) 2003-12-31
ES2179192T3 (es) 2003-01-16
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DE69622166D1 (de) 2002-08-08
AU5480996A (en) 1996-10-30
PL180900B1 (pl) 2001-04-30
BG102021A (en) 1998-07-31
EE9700280A (et) 1998-04-15
US6532955B1 (en) 2003-03-18
PL322778A1 (en) 1998-02-16
CN1217654C (zh) 2005-09-07
OA10627A (en) 2001-04-24
AP9701114A0 (en) 1997-10-31
SK281746B6 (sk) 2001-07-10
CA2217950A1 (en) 1996-10-17
DE69622166T2 (de) 2003-04-03
CY2402B1 (en) 2004-09-10
EP1870122A3 (en) 2008-03-12
EA199700231A1 (ru) 1998-02-26
EP0820279A1 (en) 1998-01-28
SI0820279T1 (en) 2002-12-31
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HUP9801526A3 (en) 2000-03-28
ES2292526T3 (es) 2008-03-16
RO119118B1 (ro) 2004-04-30
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DE69637257T2 (de) 2008-06-12
US6131566A (en) 2000-10-17
MX9707863A (es) 1997-11-29
CA2391617A1 (en) 1996-10-17

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