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ECSP13012920A - Moduladores de los receptores de hormonas nucleares - Google Patents

Moduladores de los receptores de hormonas nucleares

Info

Publication number
ECSP13012920A
ECSP13012920A ECSP13012920A ECSP13012920A EC SP13012920 A ECSP13012920 A EC SP13012920A EC SP13012920 A ECSP13012920 A EC SP13012920A EC SP13012920 A ECSP13012920 A EC SP13012920A
Authority
EC
Ecuador
Prior art keywords
modulators
hormone receptors
nuclear hormone
prodrugs
stereoisomers
Prior art date
Application number
Other languages
English (en)
Inventor
Martin E Hayes
Eric C Breinlinger
Thomas D Gordon
Anna M Ericsson
Kevin P Cusack
David C Ihle
Bin Li
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46828945&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012920(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of ECSP13012920A publication Critical patent/ECSP13012920A/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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    • C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
    • C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
    • C07C49/643—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having three rings
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Abstract

La invención proporcional una Fórmula (I), sales farmacéuticamente aceptables, prodrogas, metabolitos biológicamente activos, isómeros, y estereoisómeros donde la variable se define en este documento. Los compuestos de la invención son útiles para el tratamiento en condiciones inmunolçogicas y oncológicas.
ECSP13012920 2011-03-15 2013-10-03 Moduladores de los receptores de hormonas nucleares ECSP13012920A (es)

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