[go: up one dir, main page]

ECSP12012251A - Inhibición de efectos sensoriales no deseados a través del compuesto de alcanfor - Google Patents

Inhibición de efectos sensoriales no deseados a través del compuesto de alcanfor

Info

Publication number
ECSP12012251A
ECSP12012251A ECSP12012251A ECSP12012251A EC SP12012251 A ECSP12012251 A EC SP12012251A EC SP12012251 A ECSP12012251 A EC SP12012251A EC SP12012251 A ECSP12012251 A EC SP12012251A
Authority
EC
Ecuador
Prior art keywords
alcanfor
inhibition
composite
sensory effects
camphor
Prior art date
Application number
Other languages
English (en)
Inventor
Gerd Kobal
María Gogova
Prasad Polur
Diana Mckinney
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of ECSP12012251A publication Critical patent/ECSP12012251A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/186—Treatment of tobacco products or tobacco substitutes by coating with a coating composition, encapsulation of tobacco particles
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/34—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring
    • A24B15/345—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring containing condensed rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009—Sachets, pouches characterised by the material or function of the envelope
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacture Of Tobacco Products (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Un producto de tabaco sin humo (10, 100) o un producto de nicotina medicinal comprenden nicotina y alcanfor disuelto en un vehículo oleoso sin sabor. Preferentemente, el alcanfor está presente en una concentración que varía de aproximadamente 600 a aproximadamente 1300 ppm. También, se describen métodos para elaborar dichos productos
ECSP12012251 2010-03-26 2012-10-11 Inhibición de efectos sensoriales no deseados a través del compuesto de alcanfor ECSP12012251A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31825310P 2010-03-26 2010-03-26

Publications (1)

Publication Number Publication Date
ECSP12012251A true ECSP12012251A (es) 2012-11-30

Family

ID=44486992

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP12012251 ECSP12012251A (es) 2010-03-26 2012-10-11 Inhibición de efectos sensoriales no deseados a través del compuesto de alcanfor

Country Status (14)

Country Link
US (4) US8952038B2 (es)
EP (1) EP2552244B1 (es)
JP (1) JP5886823B2 (es)
KR (1) KR101760972B1 (es)
BR (1) BR112012024364A2 (es)
CA (1) CA2794638C (es)
DK (1) DK2552244T3 (es)
EC (1) ECSP12012251A (es)
MX (1) MX340620B (es)
MY (1) MY165804A (es)
PL (1) PL2552244T3 (es)
RU (1) RU2012145537A (es)
UA (1) UA110029C2 (es)
WO (1) WO2011117735A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8952038B2 (en) 2010-03-26 2015-02-10 Philip Morris Usa Inc. Inhibition of undesired sensory effects by the compound camphor
PL2552245T3 (pl) 2010-03-26 2019-05-31 Philip Morris Products Sa Inhibicja podrażnienia sensorycznego podczas konsumpcji produktów tytoniowych niepalnych
US8646461B2 (en) 2011-12-14 2014-02-11 Sentiens, Llc Device and method for simulating chemosensation of smoking
SE536491C2 (sv) * 2012-03-26 2013-12-27 Bionicotine Ab Påse innehållande nikotin och en tuggummikomposition
US10335378B2 (en) * 2013-03-15 2019-07-02 Altria Client Services Llc Inhibition of central nervous system effects from smoking and sensory effects from smoking
US9538782B2 (en) * 2013-03-15 2017-01-10 Altria Client Services Llc Inhibition of sensory irritation during consumption of smokeless tobacco products using a combinatorial approach
US10130120B2 (en) 2013-03-15 2018-11-20 Altria Client Services Llc Use of pectin or other anionic polymers in the stabilization and controlled release of nicotine in oral sensorial tobacco products or nicotine containing non-tobacco oral sensorial products
EP3129491A1 (en) 2014-04-08 2017-02-15 Altria Client Services LLC Tobacco having altered leaf properties and methods of making and using
US11672862B2 (en) 2019-12-09 2023-06-13 Nicoventures Trading Limited Oral products with reduced irritation
US20220087997A1 (en) * 2020-09-22 2022-03-24 Fertin Pharma A/S Oral Antagonist Compositions For Nicotine Burning Relief
EP4144230B1 (en) 2021-09-03 2024-08-07 JT International SA Chilled pouch material for nicotine pouch

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211242A (en) * 1977-11-15 1980-07-08 International Flavors & Fragrances Inc. Composition of matter comprising more than 50% trans, trans-Δ-damascone for augmenting or enhancing the aroma and taste of a smoking tobacco
US4198309A (en) * 1977-11-15 1980-04-15 International Flavors & Fragrances Inc. Use of trans, trans-Δ-damascone and mixtures containing 80% or more of trans, trans-Δ-damascone in augmenting or enhancing the aroma of a detergent
US4275251A (en) * 1980-04-29 1981-06-23 International Flavors & Fragrances Inc. Substituted tricyclodecane derivatives, processes for producing same and organoleptic uses thereof
US4378380A (en) 1980-10-10 1983-03-29 General Foods Corporation Method for producing products enhanced with synthetic coffee grinder gas flavor
US4351347A (en) * 1981-03-25 1982-09-28 International Flavors & Fragrances Inc. Organoleptic uses of norbornyl ethers and esters
US5820876A (en) 1986-08-28 1998-10-13 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system
USRE37934E1 (en) 1986-08-28 2002-12-10 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system
US6126963A (en) 1986-08-28 2000-10-03 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system, its use and production process
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
DE3827561C1 (es) 1988-08-13 1989-12-28 Lts Lohmann Therapie-Systeme Gmbh & Co Kg, 5450 Neuwied, De
US4959380A (en) 1988-12-19 1990-09-25 Wilson Jordan E Method of treating people to stop smoking and composition
US5167244A (en) * 1990-01-19 1992-12-01 Kjerstad Randy E Tobacco substitute
CA2053462A1 (en) 1990-10-22 1992-04-23 Yoshiaki Yano Sticky composition for medical use
DE4301782C1 (de) 1993-01-23 1994-08-25 Lohmann Therapie Syst Lts Verwendung von Galanthamin zur Behandlung der Nicotinabhängigkeit
JPH0782588A (ja) * 1993-09-14 1995-03-28 Sanei Gen F F I Inc 香気放出調整法
DE4341444C2 (de) 1993-12-04 1996-03-14 Lohmann Therapie Syst Lts Wirkstoffhaltiges Pflaster und Verfahren zu seiner Herstellung
US5505958A (en) 1994-10-31 1996-04-09 Algos Pharmaceutical Corporation Transdermal drug delivery device and method for its manufacture
US5716621A (en) 1996-07-03 1998-02-10 Pharmadyn, Inc. Nonocclusive drug delivery device and process for its manufacture
DE19635676A1 (de) 1996-09-03 1998-03-05 Basf Ag Feste geschäumte Wirkstoffzubereitungen
US6949264B1 (en) 1996-11-27 2005-09-27 Wm. Wrigley Jr. Company Nutraceuticals or nutritional supplements and method of making
CA2216215A1 (en) 1997-04-05 1998-10-05 Isa Odidi Controlled release formulations using intelligent polymers having opposing wettability characteristics of hydrophobicity and hydrophilicity
WO1999015210A2 (en) 1997-09-26 1999-04-01 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US20020017295A1 (en) 2000-07-07 2002-02-14 Weers Jeffry G. Phospholipid-based powders for inhalation
CN1044314C (zh) 1997-12-01 1999-07-28 蒲邯名 健身香烟
WO1999039595A1 (en) 1998-02-09 1999-08-12 Rousseau Research, Inc. Tobacco products with vitamin e
JPH11313634A (ja) 1998-03-12 1999-11-16 Internatl Flavors & Fragrances Inc <Iff> 呈味剤とその製造方法
US6270804B1 (en) 1998-04-03 2001-08-07 Biovail Technologies Ltd. Sachet formulations
US6103266A (en) 1998-04-22 2000-08-15 Tapolsky; Gilles H. Pharmaceutical gel preparation applicable to mucosal surfaces and body tissues
WO2000007603A2 (en) 1998-08-04 2000-02-17 Madash Llp End modified thermal responsive hydrogels
DE19843904A1 (de) 1998-09-24 2000-03-30 Basf Ag Feste Dosierungsform mit polymerem Bindemittel
US6165512A (en) 1998-10-30 2000-12-26 Fuisz Technologies Ltd. Dosage forms containing taste masked active agents
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US7163705B2 (en) 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
DE19906979B4 (de) 1999-02-19 2004-07-08 Lts Lohmann Therapie-Systeme Ag Verwendung von Desoxypeganin zur Behandlung der Nikotinabhängigkeit
TWI233810B (en) 1999-02-19 2005-06-11 Hisamitsu Pharmaceutical Co A paster sheet
US6183770B1 (en) 1999-04-15 2001-02-06 Acutek International Carrier patch for the delivery of agents to the skin
US7063859B1 (en) 1999-04-28 2006-06-20 Noven Pharmaceuticals, Inc. Barrier film lined backing layer composition and method for topical administration of active agents
US6277401B1 (en) 1999-05-07 2001-08-21 U.S. Dermatologics, Inc. Drug delivery device
DE19923427A1 (de) 1999-05-21 2000-11-23 Lohmann Therapie Syst Lts Vorrichtung und Verfahren zur Steigerung der transdermalen Permeation von Arzneistoffen
DE19932603A1 (de) 1999-07-13 2001-01-25 Gruenenthal Gmbh Wirkstoffhaltiger Mehrschichtfilm aus in situ vernetzten hydrophilen Polymeren
US6821953B1 (en) 1999-12-16 2004-11-23 University Of Southern California Methods for treating and preventing damage to mucosal tissue
US6582724B2 (en) 1999-12-16 2003-06-24 Dermatrends, Inc. Dual enhancer composition for topical and transdermal drug delivery
WO2001052823A2 (en) 2000-01-20 2001-07-26 Noven Pharmaceuticals, Inc. Compositions to effect the release profile in the transdermal administration of drugs
US6953593B2 (en) 2000-02-01 2005-10-11 Lipoprotein Technologies, Inc. Sustained-release microencapsulated delivery system
WO2001089476A1 (en) * 2000-05-19 2001-11-29 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
AU2000256373A1 (en) * 2000-06-26 2002-03-28 Cerami Consulting Corp. Methods, agents and devices for removing nucleophilic toxins from tobacco and tobacco smoke
DE10032456A1 (de) 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Schnell zerfallende Darreichungsform zur Freisetzung von Wirkstoffen im Mundraum oder in Körperhöhlen
DE10053375C1 (de) 2000-10-27 2002-01-24 Lohmann Therapie Syst Lts Transdermale therapeutische Systeme mit lichtempfindlichen Wirkstoffen
US6682757B1 (en) 2000-11-16 2004-01-27 Euro-Celtique, S.A. Titratable dosage transdermal delivery system
EP1366762B1 (en) 2001-03-07 2015-12-30 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
US6668839B2 (en) 2001-05-01 2003-12-30 Jonnie R. Williams Smokeless tobacco product
CA2445761C (en) * 2001-05-01 2009-10-20 Jonnie R. Williams Smokeless tobacco product
WO2002100384A1 (en) 2001-06-12 2002-12-19 Hisamitsu Pharmaceutical Co., Inc. Sheet-like patch agent
US6789546B2 (en) 2001-06-26 2004-09-14 Technion Research & Development Foundation Ltd. Filters for preventing or reducing tobacco smoke-associated injury in the aerodigestive tract of a subject
US20040224012A1 (en) 2001-10-05 2004-11-11 Pichit Suvanprakorn Topical application and methods for administration of active agents using liposome macro-beads
US6893655B2 (en) 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
EP1304048B1 (en) 2001-10-22 2004-09-22 Ivo Pera Composition to reduce or quit smoking addiction
WO2003041521A2 (en) * 2001-11-09 2003-05-22 Vector Tobacco Inc. Method and composition for mentholation of charcoal filtered cigarettes
GB0130518D0 (en) 2001-12-21 2002-02-06 Univ Gent Pulsed bio-agent delivery systems based on degradable polymer solutions or hydrogels
US6750291B2 (en) 2002-04-12 2004-06-15 Pacific Corporation Film-forming agent for drug delivery and preparation for percutaneous administration containing the same
AR033748A1 (es) 2002-05-15 2004-01-07 Thalas Group Inc Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo
JP4199485B2 (ja) 2002-06-07 2008-12-17 久光製薬株式会社 貼付剤
EP1513532B1 (en) 2002-06-10 2007-02-28 Euro-Celtique S.A. Disposal systems of transdermal delivery devices to prevent misuse of the active agents contained therein
JP4792193B2 (ja) 2002-08-28 2011-10-12 久光製薬株式会社 貼付剤
SE0302947D0 (sv) 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
WO2004064811A1 (en) * 2003-01-24 2004-08-05 Magle Holding Ab A composition material for transmucosal delivery
JP2004229627A (ja) * 2003-01-29 2004-08-19 Yoshiaki Fujiyama 鼻で吸うタバコ代用物
US20040151771A1 (en) * 2003-02-04 2004-08-05 Gin Jerry B. Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth
US20040202708A1 (en) 2003-04-14 2004-10-14 3M Innovative Properties Company Transdermal drug delivery device with translucent inorganic barrier layer
US20040219198A1 (en) 2003-05-01 2004-11-04 3M Innovative Properties Company Transdermal drug delivery device with multilayer backing
EP1652523A4 (en) 2003-08-04 2008-11-19 Kyorin Seiyaku Kk TRANSDERMALES ABSORPTION PREPARATION
WO2005041151A2 (en) 2003-10-02 2005-05-06 Vector Tobacco Ltd. Tobacco product labeling system
US20050118246A1 (en) 2003-10-31 2005-06-02 Wong Patrick S. Dosage forms and layered deposition processes for fabricating dosage forms
CN1878528A (zh) 2003-11-12 2006-12-13 西姆莱斯有限责任两合公司 具有冬青气味和风味的混合物
DE10356925B4 (de) 2003-12-05 2006-05-11 Lts Lohmann Therapie-Systeme Ag Inhalator für basische pharmazeutische Wirkstoffe sowie Verfahren für dessen Herstellung
US20050136112A1 (en) 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
CN1579258A (zh) 2004-05-18 2005-02-16 王自勇 一种新型鼻烟及其制作方法
US7923585B2 (en) 2004-05-31 2011-04-12 Takasago International Corporation Menthol derivative and cooling agent composition comprising the same
TW200628175A (en) 2004-10-08 2006-08-16 Noven Pharma Transdermal drug delivert device including an occlusive backing
JP2008517938A (ja) 2004-10-25 2008-05-29 シェーリング コーポレイション 呼吸器障害を処置するために他の活性剤と組み合わせたｍ１レセプターアンタゴニストおよび／またはｍ３レセプターアンタゴニスト
US20060110415A1 (en) 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
MX2007007328A (es) 2004-12-22 2007-07-25 Memory Pharm Corp Ligandos del receptor alfa-7 nicotinico y preparacion y sus usos.
RU2007127999A (ru) 2004-12-23 2009-01-27 МакНЕЙЛ-ППС, ИНК. (US) Орально распадающееся фармацевтические композиции с сенсорными сигнальными агентами
US7534454B2 (en) 2004-12-28 2009-05-19 Arun Kumar Karerat Anti-cigarette herbal formulation as an antidote to tobacco
US20060228418A1 (en) 2005-04-12 2006-10-12 Aquegel Cosmetics, Llc Topical ointment and method for making and using same
US20070026025A1 (en) 2005-04-12 2007-02-01 Aquegel Cosmetics, Llc Topical ointment and method for making and using same
WO2006120570A2 (en) 2005-04-29 2006-11-16 Philip Morris Products S.A. Tobacco pouch product
US9044049B2 (en) 2005-04-29 2015-06-02 Philip Morris Usa Inc. Tobacco pouch product
US20090175982A1 (en) 2005-05-23 2009-07-09 Cadbury Adams Usa Llc., Methods for managing release of one or more ingredients in an edible composition
US7186958B1 (en) 2005-09-01 2007-03-06 Zhao Wei, Llc Inhaler
US20070074733A1 (en) 2005-10-04 2007-04-05 Philip Morris Usa Inc. Cigarettes having hollow fibers
JP2009529561A (ja) 2006-03-16 2009-08-20 ニコノヴァム エービー ニコチンの速やかな放出をもたらす安定なロゼンジ組成物
US20080063748A1 (en) 2006-09-08 2008-03-13 Cadbury Adams Usa Llc. Center-fill confectionery and chewing gum compositions containing suspended saccharide particles
US20080102157A1 (en) 2006-10-25 2008-05-01 Steffen Hofacker Flavored chewable foams and a process for their production
US9032971B2 (en) 2006-11-15 2015-05-19 Philip Morris Usa Inc. Moist tobacco product and method of making
US20080131467A1 (en) 2006-11-30 2008-06-05 Dennis Nelson Film-coated solid dosage form
WO2008069970A2 (en) * 2006-12-01 2008-06-12 Aradigm Corporation Nicotine formulations, kits and systems and methods for their use
US20080247957A1 (en) * 2007-02-16 2008-10-09 Drexel University Advanced drug delivery strategy and platform for minimally-invasive treatment of liver cancer
US8616221B2 (en) 2007-02-28 2013-12-31 Philip Morris Usa Inc. Oral pouch product with flavored wrapper
WO2008112124A2 (en) * 2007-03-07 2008-09-18 Novartis Ag Orally administrable films
US20090032040A1 (en) 2007-03-30 2009-02-05 Luzenberg Jr Robert S Porous plastic smokeless tobacco substitutes
AU2008259951B2 (en) 2007-06-01 2011-10-06 Intercontinental Great Brands Llc Center-fill gum compositions incorporating triacetin
US8901024B2 (en) 2007-08-02 2014-12-02 The Trustees Of Columbia University In The City Of New York Ozone-treated carbon electrodes
US8312886B2 (en) 2007-08-09 2012-11-20 Philip Morris Usa Inc. Oral tobacco product having a hydrated membrane coating and a high surface area
JP2009148233A (ja) * 2007-12-21 2009-07-09 Japan Tobacco Inc 喫煙物品
US8469037B2 (en) 2008-02-08 2013-06-25 Philip Morris Usa Inc. Pre-portioned moist product and method of making
CN102905566A (zh) * 2008-07-28 2013-01-30 R.J.雷诺兹烟草公司 无烟烟草产品和工艺
US20100018883A1 (en) * 2008-07-28 2010-01-28 Pankaj Patel Smokeless tobacco products and processes
PL2552245T3 (pl) * 2010-03-26 2019-05-31 Philip Morris Products Sa Inhibicja podrażnienia sensorycznego podczas konsumpcji produktów tytoniowych niepalnych
US8952038B2 (en) 2010-03-26 2015-02-10 Philip Morris Usa Inc. Inhibition of undesired sensory effects by the compound camphor
US9474303B2 (en) * 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
KR20140116531A (ko) * 2012-01-25 2014-10-02 니뽄 다바코 산교 가부시키가이샤 담배 취구취 개선 향료 조성물

Also Published As

Publication number Publication date
KR101760972B1 (ko) 2017-07-24
US20120052021A1 (en) 2012-03-01
UA110029C2 (uk) 2015-11-10
MY165804A (en) 2018-04-27
WO2011117735A8 (en) 2011-11-10
CA2794638C (en) 2018-05-29
US11388923B2 (en) 2022-07-19
WO2011117735A2 (en) 2011-09-29
EP2552244B1 (en) 2018-02-21
EP2552244A2 (en) 2013-02-06
JP2013523090A (ja) 2013-06-17
US10201180B2 (en) 2019-02-12
DK2552244T3 (en) 2018-03-19
CA2794638A1 (en) 2011-09-29
US20150126561A1 (en) 2015-05-07
US20190133175A1 (en) 2019-05-09
WO2011117735A3 (en) 2012-05-18
KR20130029067A (ko) 2013-03-21
BR112012024364A2 (pt) 2020-08-11
JP5886823B2 (ja) 2016-03-16
US8952038B2 (en) 2015-02-10
MX340620B (es) 2016-07-18
PL2552244T3 (pl) 2018-07-31
RU2012145537A (ru) 2014-05-10
US20220361555A1 (en) 2022-11-17
MX2012011150A (es) 2013-03-05

Similar Documents

Publication Publication Date Title
ECSP12012251A (es) Inhibición de efectos sensoriales no deseados a través del compuesto de alcanfor
Gadkari et al. Catechins: Sources, extraction and encapsulation: A review
MY184353A (en) Flavor capsules for smoking articles
MX350636B (es) Inhibicion de irritacion sensorial durante el consumo de productos de tabaco no fumables.
ES2722948T3 (es) Filtro con dureza y eficacia de filtración mejoradas
CL2015000486A1 (es) Composición de nicotina
AR095612A1 (es) Modificación del gusto e irritación sensorial del tabaco sin humo y los productos no-tabaco
EA201290809A1 (ru) Аэрозоль-генерирующий субстрат для курительных изделий
MY186135A (en) Tobacco composition
UA113765C2 (xx) Ароматизовані прутки, призначені для використання у аерозолеутворювальних виробах
WO2012158915A3 (en) Molecularly imprinted polymers for treating tobacco material and filtering smoke from smoking articles
MY188956A (en) Processes for producing lipids
MX2017005196A (es) Envoltura hidrofoba.
MY191357A (en) Sustained-release dosage forms of ruxolitinib
BR112014010912A2 (pt) artigo de fumar compreendendo mentol
AR076532A1 (es) Filtro para un articulo para fumar
WO2012005885A3 (en) Nutraceutical product containing anatabine and yerba maté
MX2013004712A (es) Articulo para fumar ventilado.
CL2017000536A1 (es) Una composición modificadora del sabor, usos de la misma y productos que comprenden la misma
ATE526015T1 (de) Arzneimittel sowie deren herstellung und verwendung bei der behandlung von schmerzhaften neuropathien
PH12017500563A1 (en) Stabilized adrenomedullin derivatives and use thereof
CL2015002375A1 (es) Proceso para la fabricación de productos a partir de fibra de madera acetilada.
PE20151878A1 (es) Fibra de madera acetilada
MX2014004218A (es) Articulo para fumar de segmentos multiples.
UA117544C2 (uk) Назальна композиція із вмістом морської води як ексципієнтом, що покращує стабільність