ECSP003694A - Kit combinado para el tratamiento de la malaria - Google Patents
Kit combinado para el tratamiento de la malariaInfo
- Publication number
- ECSP003694A ECSP003694A EC2000003694A ECSP003694A ECSP003694A EC SP003694 A ECSP003694 A EC SP003694A EC 2000003694 A EC2000003694 A EC 2000003694A EC SP003694 A ECSP003694 A EC SP003694A EC SP003694 A ECSP003694 A EC SP003694A
- Authority
- EC
- Ecuador
- Prior art keywords
- treatment
- amino
- day
- malaria
- furanone
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 201000004792 malaria Diseases 0.000 title abstract 2
- 239000003430 antimalarial agent Substances 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- -1 6-methoxy-8-quinolinyl Chemical group 0.000 abstract 2
- 241000223810 Plasmodium vivax Species 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 2
- 230000003203 everyday effect Effects 0.000 abstract 2
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 abstract 2
- WHTVZRBIWZFKQO-AWEZNQCLSA-N (S)-chloroquine Chemical compound ClC1=CC=C2C(N[C@@H](C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-AWEZNQCLSA-N 0.000 abstract 1
- AEUAEICGCMSYCQ-UHFFFAOYSA-N 4-n-(7-chloroquinolin-1-ium-4-yl)-1-n,1-n-diethylpentane-1,4-diamine;dihydrogen phosphate Chemical compound OP(O)(O)=O.ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 AEUAEICGCMSYCQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010035503 Plasmodium vivax infection Diseases 0.000 abstract 1
- 229960003677 chloroquine Drugs 0.000 abstract 1
- WHTVZRBIWZFKQO-UHFFFAOYSA-N chloroquine Natural products ClC1=CC=C2C(NC(C)CCCN(CC)CC)=CC=NC2=C1 WHTVZRBIWZFKQO-UHFFFAOYSA-N 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000011269 treatment regimen Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Un estuche de combinación para el tratamiento del paludismo producido por Plasmodium vivax (p.vivax), que tiene dosis individuales de un agente antipalúdico, 3-[1-[[4-[(6-metoxi-8-quinolinil)amino]pentil}amino}etilideno]-dihidro-2-(3H)furanona (I) en forma de cápsulas; dosis individuales del agente antipalúdico cloroquina en forma de comprimidos; y material de instrucciones para la administración de los dos fármacos antipalúdicos. El estuche de combinación es particularmente adecuado para un régimen de tratamiento de 6 días, en el que el tratamiento se consigue mediante cinco comprimidos que contienen 500 mg de fosfato de cloroquinina (equivalentes a 300 mg de base), debiendo tomarse tres el d{ia uno y uno cada uno de los días dos y tres; y cinco cápsulas que contienen 25 mg de 3-[1-[[4-[(6-metoxi-8-quinolinil) amino]pentil]amino}etilideno]-dihidro-2(3H)furanona (I), debiendo tomarse una cada uno de los dias dos a seis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN501MU2000 | 2000-05-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003694A true ECSP003694A (es) | 2002-01-25 |
Family
ID=11097250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2000003694A ECSP003694A (es) | 2000-05-31 | 2000-10-05 | Kit combinado para el tratamiento de la malaria |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US7404962B1 (es) |
| EP (1) | EP1292306B1 (es) |
| JP (1) | JP2004505017A (es) |
| KR (1) | KR20030025926A (es) |
| AP (1) | AP1435A (es) |
| AR (1) | AR028458A1 (es) |
| AT (1) | ATE314848T1 (es) |
| AU (2) | AU2001228790B2 (es) |
| BR (1) | BR0005247A (es) |
| CA (1) | CA2413775C (es) |
| CR (1) | CR6835A (es) |
| CZ (1) | CZ296875B6 (es) |
| DE (2) | DE60025403T2 (es) |
| DK (1) | DK1292306T3 (es) |
| EC (1) | ECSP003694A (es) |
| ES (1) | ES2200729T3 (es) |
| GT (1) | GT200000187A (es) |
| HK (1) | HK1052467B (es) |
| HN (1) | HN2001000118A (es) |
| HU (1) | HUP0301925A3 (es) |
| MX (1) | MXPA02011883A (es) |
| NO (1) | NO324774B1 (es) |
| OA (1) | OA12276A (es) |
| PE (1) | PE20011319A1 (es) |
| PL (1) | PL200748B1 (es) |
| SV (1) | SV2002000201A (es) |
| WO (1) | WO2001091535A2 (es) |
| ZA (1) | ZA200209726B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009527478A (ja) * | 2006-02-16 | 2009-07-30 | ザ マクレーン ホスピタル コーポレーション | パーキンソン病の治療のための方法と組成物 |
| WO2010065932A1 (en) * | 2008-12-05 | 2010-06-10 | Designmedix, Inc. | Modified chloroquines with single ring moiety or fused ring moiety |
| WO2010144102A1 (en) * | 2009-06-09 | 2010-12-16 | The United States Of America, As Represented By The Secretary Of The Army, On Behalf Of U.S. Army Medical Research And Material Command | Pentafluorosulfanyl analogs of mefloquine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431807A (en) * | 1980-06-12 | 1984-02-14 | The United States Of America As Represented By The Secretary Of The Army | 4-Methyl-5-(unsubstituted and substituted phenoxy)-6-methoxy-8-(aminoalkylamino)quinolines |
| US5219865A (en) * | 1987-05-08 | 1993-06-15 | Hoechst Aktiengesellschaft | Pharmaceutical combination for the prophylaxis and therapy of malaria |
| US5373005A (en) * | 1988-04-20 | 1994-12-13 | Merrell Dow Pharmaceuticals Inc. | Despiramine in the treatment of drug-resistant malarial infections |
| US5270037A (en) * | 1990-07-12 | 1993-12-14 | Boehringer Ingelheim Gmbh | Use of interferon and a substance with an antimalarial activity for the treatment of malaria infections |
| SG45193A1 (en) * | 1992-02-07 | 1998-01-16 | Ciba Geigy Ag | Antimalarial synergistic compositions containing benflumetol |
-
2000
- 2000-08-30 MX MXPA02011883A patent/MXPA02011883A/es active IP Right Grant
- 2000-08-30 AU AU2001228790A patent/AU2001228790B2/en not_active Ceased
- 2000-08-30 HU HU0301925A patent/HUP0301925A3/hu unknown
- 2000-08-30 HK HK03104811.6A patent/HK1052467B/en not_active IP Right Cessation
- 2000-08-30 CZ CZ20024071A patent/CZ296875B6/cs not_active IP Right Cessation
- 2000-08-30 JP JP2001587559A patent/JP2004505017A/ja active Pending
- 2000-08-30 US US10/296,215 patent/US7404962B1/en not_active Expired - Fee Related
- 2000-08-30 WO PCT/IN2000/000081 patent/WO2001091535A2/en not_active Ceased
- 2000-08-30 AT AT00993875T patent/ATE314848T1/de active
- 2000-08-30 DE DE60025403T patent/DE60025403T2/de not_active Expired - Lifetime
- 2000-08-30 DE DE0001292306T patent/DE00993875T1/de active Pending
- 2000-08-30 ES ES00993875T patent/ES2200729T3/es not_active Expired - Lifetime
- 2000-08-30 EP EP00993875A patent/EP1292306B1/en not_active Expired - Lifetime
- 2000-08-30 DK DK00993875T patent/DK1292306T3/da active
- 2000-08-30 PL PL372718A patent/PL200748B1/pl not_active IP Right Cessation
- 2000-08-30 OA OA1200200359A patent/OA12276A/en unknown
- 2000-08-30 AP APAP/P/2002/002672A patent/AP1435A/en active
- 2000-08-30 KR KR1020027016169A patent/KR20030025926A/ko not_active Ceased
- 2000-08-30 CA CA002413775A patent/CA2413775C/en not_active Expired - Fee Related
- 2000-08-30 AU AU2879001A patent/AU2879001A/xx active Pending
- 2000-10-05 EC EC2000003694A patent/ECSP003694A/es unknown
- 2000-10-13 SV SV2000000201A patent/SV2002000201A/es unknown
- 2000-10-25 GT GT200000187A patent/GT200000187A/es unknown
- 2000-11-06 BR BR0005247-7A patent/BR0005247A/pt not_active Application Discontinuation
-
2001
- 2001-05-14 AR ARP010102288A patent/AR028458A1/es unknown
- 2001-05-23 PE PE2001000469A patent/PE20011319A1/es not_active Application Discontinuation
- 2001-05-30 HN HN2001000118A patent/HN2001000118A/es unknown
-
2002
- 2002-11-28 CR CR6835A patent/CR6835A/es not_active Application Discontinuation
- 2002-11-29 ZA ZA200209726A patent/ZA200209726B/en unknown
- 2002-11-29 NO NO20025765A patent/NO324774B1/no not_active IP Right Cessation
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