EA201000213A1 - Method of general anesthesia - Google Patents
Method of general anesthesiaInfo
- Publication number
- EA201000213A1 EA201000213A1 EA201000213A EA201000213A EA201000213A1 EA 201000213 A1 EA201000213 A1 EA 201000213A1 EA 201000213 A EA201000213 A EA 201000213A EA 201000213 A EA201000213 A EA 201000213A EA 201000213 A1 EA201000213 A1 EA 201000213A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- anesthesia
- tramadol
- dose
- recofol
- epidural
- Prior art date
Links
- 238000002695 general anesthesia Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N (R,R)-tramadol Chemical compound COC1=CC=CC([C@]2(O)[C@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-ZBFHGGJFSA-N 0.000 abstract 5
- 206010002091 Anaesthesia Diseases 0.000 abstract 5
- 230000037005 anaesthesia Effects 0.000 abstract 5
- 229960004380 tramadol Drugs 0.000 abstract 5
- TVYLLZQTGLZFBW-GOEBONIOSA-N tramadol Natural products COC1=CC=CC([C@@]2(O)[C@@H](CCCC2)CN(C)C)=C1 TVYLLZQTGLZFBW-GOEBONIOSA-N 0.000 abstract 5
- 238000001990 intravenous administration Methods 0.000 abstract 4
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 abstract 4
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 abstract 2
- 230000036592 analgesia Effects 0.000 abstract 2
- 230000002980 postoperative effect Effects 0.000 abstract 2
- 238000001356 surgical procedure Methods 0.000 abstract 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 abstract 1
- TXWBOBJCRVVBJF-YTGGZNJNSA-L Pipecuronium bromide Chemical compound [Br-].[Br-].N1([C@@H]2[C@@H](OC(C)=O)C[C@@H]3CC[C@H]4[C@@H]5C[C@@H]([C@@H]([C@]5(CC[C@@H]4[C@@]3(C)C2)C)OC(=O)C)N2CC[N+](C)(C)CC2)CC[N+](C)(C)CC1 TXWBOBJCRVVBJF-YTGGZNJNSA-L 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000004 hemodynamic effect Effects 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 229960004194 lidocaine Drugs 0.000 abstract 1
- 239000003589 local anesthetic agent Substances 0.000 abstract 1
- 230000000978 myorelaxation Effects 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 239000002504 physiological saline solution Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение относится к медицине, а именно к анестезиологии-реаниматологии, может использоваться для проведения общего обезболивания. Способ обеспечивает адекватную защиту пациента от хирургической боли, как во время операции, так и в послеоперационном периоде введением анальгетика трамадол внутривенно и в эпидуральное пространство в общей суммарной дозе 100 мг. В операционной предварительно осуществлялась катетеризация эпидурального пространства на уровне Th-Th, после введения тест-дозы (2% лидокаин 50 мг трамадол), проводился вводный наркоз рекофолом в дозе 1,5-2,5 мг/кг массы тела внутривенно болюсно с интервалом 10 с. Основной наркоз рекофол в режиме 20-30 мл/ч вводился внутривенно шприцевым насосом SEP-10S. Миорелаксацию проводили листеноном и ардуаном. Анальгезия поддерживалась внутривенным капельным введением трамадола на физиологическом растворе в дозе 50 мг, с внутривенным введением рекофола, через шприцевой насос, а также перед разрезом кожи вводили 50 мг калипсола в общей суммарной дозе 150 мг за весь период анестезии, для поддержания хирургической стадий наркоза. Анальгезия внутривенным и эпидуральным введением трамадола в комбинации с внутривенным анестетиком рекофол и субнаркотических доз калипсола с эпидуральным блоком стабилизировали лабораторные и гемодинамические показатели. Изобретение позволяет полностью отказаться от применения в большой хирургии морфиноподобных анальгетиков, позволяет повысить эффективность и безопасность общего обезболивания с последующим обезболиванием послеоперационного периода, эпидуральным введением трамадола без использования растворов местных анестетиков, тем самым исключаяThe invention relates to medicine, namely to anesthesiology and intensive care, can be used for general anesthesia. The method provides adequate protection of the patient from surgical pain, both during surgery and in the postoperative period by administering the analgesic tramadol intravenously and into the epidural space in a total total dose of 100 mg. In the operating room, catheterization of the epidural space at the Th-Th level was carried out previously, after administration of the test dose (2% lidocaine 50 mg tramadol), induction anesthesia was performed with recofol at a dose of 1.5-2.5 mg / kg body weight intravenously with an interval of 10 with. The main anesthesia Recofol was administered intravenously with a syringe pump SEP-10S at a rate of 20-30 ml / h. Myorelaxation was performed with leafen and arduan. Analgesia was maintained by intravenous drip of tramadol in physiological saline at a dose of 50 mg, with intravenous administration of recofol, through a syringe pump, and before the skin incision, 50 mg of calypsol was administered in a total total dose of 150 mg for the entire anesthesia period, to maintain the surgical stages of anesthesia. Analgesia by intravenous and epidural administration of tramadol in combination with an intravenous anesthetic of recofol and sub-narcotic doses of calypsol with an epidural block stabilized laboratory and hemodynamic parameters. The invention completely eliminates the use of morphine-like analgesics in large surgery, improves the efficiency and safety of general anesthesia with subsequent postoperative anesthesia, epidural administration of tramadol without using local anesthetic solutions, thereby excluding
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EA201000213A EA017624B1 (en) | 2009-12-24 | 2009-12-24 | Method of general anesthesia |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EA201000213A EA017624B1 (en) | 2009-12-24 | 2009-12-24 | Method of general anesthesia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201000213A1 true EA201000213A1 (en) | 2011-06-30 |
| EA017624B1 EA017624B1 (en) | 2013-01-30 |
Family
ID=44356393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201000213A EA017624B1 (en) | 2009-12-24 | 2009-12-24 | Method of general anesthesia |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA017624B1 (en) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2016586C1 (en) * | 1991-10-15 | 1994-07-30 | Московский научно-исследовательский онкологический институт им.П.А.Герцена | Method of general anesthesia |
-
2009
- 2009-12-24 EA EA201000213A patent/EA017624B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA017624B1 (en) | 2013-01-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Troncy et al. | Results of preemptive epidural administration of morphine with or without bupivacaine in dogs and cats undergoing surgery: 265 cases (1997–1999) | |
| Eroglu et al. | A clinical comparison of equal concentration and volume of ropivacaine and bupivacaine for interscalene brachial plexus anesthesia and analgesia in shoulder surgery | |
| ES2727292T3 (en) | Combined formulations of neosaxitonin for prolonged local anesthesia | |
| BR0314111A (en) | Method and device for painless medication injection | |
| Pal | Can systemic lidocaine be used in controlled hypotension? A double-blinded randomized controlled study in patients undergoing functional endoscopic sinus surgery | |
| Ko et al. | Comparison of the effects of acetaminophen to ketorolac when added to lidocaine for intravenous regional anesthesia | |
| EP3045179B1 (en) | Local anesthesia pain-relieving time-delay agent | |
| Lee et al. | The analgesic effect of single dose of intrathecal magnesium sulfate | |
| Abdelnaim et al. | Comparison between bupivacaine–dexmedetomidine mixture and bupivacaine–magnesium mixture when used for wound infiltration before skin incision in surgeries for hernia repair regarding their intraoperative and postoperative analgesic effects | |
| RU2372107C1 (en) | Method of inter scalariform block brachial plexus in operations of upper extremity and clavicle | |
| EA201000213A1 (en) | Method of general anesthesia | |
| Xu et al. | [Retracted] Analysis of Anesthesia Effect of Dexmedetomidine in Clinical Operation of Replantation of Severed Finger | |
| Lim et al. | Opioid-sparing anesthesia for open total pancreatectomy and splenectomy using the external oblique intercostal (EOI) block: A case report | |
| CN101522180A (en) | Methods for delivering volatile anesthetics for regional anesthesia and/or pain relief | |
| RU2367424C1 (en) | Technique for anesthesia following minimally invasive abdominal surgeries | |
| RU2014154396A (en) | LIQUID MEDICINAL CONTAINING CARBON OXIDE DISSOLVED IN IT AND THE THERAPEUTIC METHOD OF USE | |
| Tulgar et al. | ESRA19-0505 New indication for novel block: sacral erector spinae plane block for inferior cluneal/sacral nerve entrapment syndrome | |
| Robinson et al. | Non-neuraxial analgesia in labour | |
| RU2008121304A (en) | METHOD OF THERAPY BLOCKING AT THE BUTTOMAL SYNDROME | |
| RU2557882C1 (en) | Method of carrying out premedication in planned surgery | |
| RU2493884C2 (en) | Method for combined general anaesthesia in combination with deep and superficial cervical plexus blockade in carotide endaterectomy or internal carotid artery resection after pathological deformation thereof | |
| RU2339367C2 (en) | Method for multi-component and multi-level regional anaesthesia in extremities surgery | |
| Eldaba et al. | Different local anesthetic technique for postoperative analgesia in open cholecystectomy | |
| Vaddi et al. | A comparative study of 0.5% ropivacaine vs 0.25% bupivacaine in transverse abdominis plane block for post operative analgesia in patients undergoing abdominal surgeries | |
| Hasan et al. | Comparison of keorolac with morphine for intraoperative analgesia in patients undergoing total abdominal hysterectomy |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |