EA199700209A1 - ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА - Google Patents

ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА

Info

Publication number: EA199700209A1
Authority: EA; Eurasian Patent Office
Prior art keywords: alkyl; halogen; formula; imidazo; pyridine derivatives
Prior art date: 1995-04-04

Application number

EA199700209A

Other languages

English (en)

Russian (ru)

Inventor

Пол Джон Бесвик

Айан Бэкстер Кэмпбелл

Элан Нейлор

Original Assignee

Глаксо Груп Лимитед

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-04-04

Filing date

1996-04-02

Publication date

1998-04-30

1995-04-04 Priority claimed from GBGB9506965.4A external-priority patent/GB9506965D0/en

1995-06-14 Priority claimed from GBGB9512099.4A external-priority patent/GB9512099D0/en

1995-08-05 Priority claimed from GBGB9516117.0A external-priority patent/GB9516117D0/en

1996-04-02 Application filed by Глаксо Груп Лимитед filed Critical Глаксо Груп Лимитед

1998-04-30 Publication of EA199700209A1 publication Critical patent/EA199700209A1/ru

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pain & Pain Management (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

EA199700209A 1995-04-04 1996-04-02 ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА EA199700209A1 (ru)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9506965.4A GB9506965D0 (en)	1995-04-04	1995-04-04	Chemical compounds
GBGB9512099.4A GB9512099D0 (en)	1995-06-14	1995-06-14	Chemical compounds
GBGB9516117.0A GB9516117D0 (en)	1995-08-05	1995-08-05	Chemical compounds
PCT/EP1996/001438 WO1996031509A1 (en)	1995-04-04	1996-04-02	IMIDAZO[1,2-a]PYRIDINE DERIVATIVES

Publications (1)

Publication Number	Publication Date
EA199700209A1 true EA199700209A1 (ru)	1998-04-30

Family

ID=27267657

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EA199700209A EA199700209A1 (ru)	1995-04-04	1996-04-02	ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА

Country Status (17)

Country	Link
EP (1)	EP0819127A1 (is)
JP (1)	JPH11501049A (is)
KR (1)	KR19980703559A (is)
CN (1)	CN1186492A (is)
AU (1)	AU5276696A (is)
BG (1)	BG101934A (is)
CA (1)	CA2216809A1 (is)
CZ (1)	CZ313397A3 (is)
EA (1)	EA199700209A1 (is)
HU (1)	HUP9801602A3 (is)
IS (1)	IS4570A (is)
NO (1)	NO974595L (is)
NZ (1)	NZ304886A (is)
PL (1)	PL322623A1 (is)
SK (1)	SK133297A3 (is)
TR (1)	TR199701105T1 (is)
WO (1)	WO1996031509A1 (is)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2764292B1 (fr) *	1997-06-10	2000-12-29	Innothera Lab Sa	Utilisation de derives de tetracycles dicetoniques, nouveaux composes obtenus et leur application en therapeutique
US6307047B1 (en)	1997-08-22	2001-10-23	Abbott Laboratories	Prostaglandin endoperoxide H synthase biosynthesis inhibitors
US6525053B1 (en)	1997-08-22	2003-02-25	Abbott Laboratories	Prostaglandin endoperoxide H synthase biosynthesis inhibitors
CA2303152A1 (en)	1997-09-05	1999-03-18	Glaxo Group Limited	2,3-diaryl-pyrazolo[1,5-b]pyridazines derivatives, their preparation and their use as cyclooxygenase 2 (cox-2) inhibitors
FR2770131A1 (fr) *	1997-10-27	1999-04-30	Union Pharma Scient Appl	Nouvelle association pharmaceutique a activite analgesique
FR2771005B1 (fr) *	1997-11-18	2002-06-07	Union Pharma Scient Appl	Nouvelle association pharmaceutique a activite analgesique
GB9810920D0 (en) *	1998-05-21	1998-07-22	Merck Sharp & Dohme	Therapeutic use
ES2140354B1 (es) *	1998-08-03	2000-11-01	S A L V A T Lab Sa	Imidazo (1,2a) azinas sustituidas como inhibidores selectivos de la cox-2.
TW587079B (en) *	1998-09-25	2004-05-11	Almirall Prodesfarma Ag	2-phenylpyran-4-one derivatives
ES2228127T3 (es) *	1998-11-03	2005-04-01	Glaxo Group Limited	Derivados de pirazolopiridina como inhibidores selectivos de cox-2.
ATE261444T1 (de) *	1999-02-27	2004-03-15	Glaxo Group Ltd	Pyrazolopyridine
PT1175214E (pt)	1999-12-08	2005-04-29	Pharmacia Corp	Composicoes de inibidor de ciclo-oxigenase-2 com um inicio rapido do seu efito terapeutico
GB9930358D0 (en)	1999-12-22	2000-02-09	Glaxo Group Ltd	Process for the preparation of chemical compounds
CA2393724A1 (en)	1999-12-23	2001-06-28	Nitromed, Inc.	Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use
GB0002312D0 (en) *	2000-02-01	2000-03-22	Glaxo Group Ltd	Medicaments
PE20011333A1 (es)	2000-03-16	2002-01-16	Almirall Prodesfarma Ag	Derivados de 2-fenilpiran-4-ona como inhibidores de ciclooxigenasa 2
PE20020146A1 (es) *	2000-07-13	2002-03-31	Upjohn Co	Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
HUP0302068A3 (en)	2000-07-20	2005-05-30	Lauras As	Use of cox-2 inhibitors for treating or preventing immunodeficiency and pharmaceutical compositions containing them
PE20020506A1 (es)	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
GB0025449D0 (en) *	2000-10-17	2000-11-29	Glaxo Group Ltd	Chemical compounds
JP2004515550A (ja)	2000-12-15	2004-05-27	グラクソグループリミテッド	治療用化合物
ES2245380T3 (es)	2000-12-15	2006-01-01	Glaxo Group Limited	Pirazolopiridinas.
EP1366048B1 (en)	2001-03-08	2004-08-25	SmithKline Beecham Corporation	Pyrazolopyridine derivatives
WO2002078700A1 (en)	2001-03-30	2002-10-10	Smithkline Beecham Corporation	Pyralopyridines, process for their preparation and use as therapteutic compounds
MY137736A (en)	2001-04-03	2009-03-31	Pharmacia Corp	Reconstitutable parenteral composition
DE60212949T2 (de)	2001-04-10	2007-01-04	Smithkline Beecham Corp.	Antivirale pyrazolopyridin verbindungen
DE60204452T2 (de)	2001-04-27	2005-12-15	Smithkline Beecham Corp.	Pyrazolo[1,5a]Pyridinderivate
US6756498B2 (en)	2001-04-27	2004-06-29	Smithkline Beecham Corporation	Process for the preparation of chemical compounds
PL366827A1 (en)	2001-06-21	2005-02-07	Smithkline Beecham Corporation	Imidazo[1,2-a]pyridine derivatives for the prophylaxis and treatment of herpes viral infections
AR038957A1 (es)	2001-08-15	2005-02-02	Pharmacia Corp	Terapia de combinacion para el tratamiento del cancer
DE60211539T2 (de)	2001-10-05	2006-09-21	Smithkline Beecham Corp.	Imidazopyridinderivate zur verwendung bei der behandlung von herpes-vireninfektion
GB0124938D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124939D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124941D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124933D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124936D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124931D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
GB0124934D0 (en)	2001-10-17	2001-12-05	Glaxo Group Ltd	Chemical compounds
AU2002357740A1 (en)	2001-12-11	2003-06-23	Smithkline Beecham Corporation	Pyrazolo-pyridine derivatives as antiherpes agents
SI1474395T1 (sl)	2002-02-12	2008-02-29	Smithkline Beecham Corp	Nikotinamidni derivati, uporabni kot inhibitorji p38
WO2004002420A2 (en)	2002-06-28	2004-01-08	Nitromed, Inc.	Oxime and/or hydrazone containing nitrosated and/or nitrosylated cyclooxigenase-2 selective inhibitors, compositions and methods of use
GB0217757D0 (en)	2002-07-31	2002-09-11	Glaxo Group Ltd	Novel compounds
WO2004033454A1 (en)	2002-10-03	2004-04-22	Smithkline Beecham Corporation	Therapeutic compounds based on pyrazolopyridine derivatives
KR20040072004A (ko)	2003-02-07	2004-08-16	삼성에스디아이 주식회사	유기 전계 발광 소자용 발광 화합물 및 그를 이용한 유기전계발광 소자
GB0308201D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308185D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
GB0308186D0 (en)	2003-04-09	2003-05-14	Smithkline Beecham Corp	Novel compounds
PL1534305T3 (pl)	2003-05-07	2007-03-30	Osteologix As	Leczenie zaburzeń chrząstek i kości solami strontu rozpuszczalnymi w wodzie
GB0318814D0 (en)	2003-08-11	2003-09-10	Smithkline Beecham Corp	Novel compounds
WO2006041855A2 (en)	2004-10-04	2006-04-20	Nitromed, Inc.	Compositions and methods using apocynin compounds and nitric oxide donors
US20090018091A1 (en)	2005-08-02	2009-01-15	Nitromed, Inc.	Nitric Oxide Enhancing Antimicrobial Compounds, Compositions and Methods of Use
CA2647859C (en)	2006-03-29	2016-01-05	Nitromed, Inc.	Nitric oxide enhancing prostaglandin compounds, compositions and methods of use
AU2007316417B2 (en)	2006-11-06	2013-08-22	Tolero Pharmaceuticals, Inc.	Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors
US9416132B2 (en)	2011-07-21	2016-08-16	Tolero Pharmaceuticals, Inc.	Substituted imidazo[1,2-b]pyridazines as protein kinase inhibitors
EP3292213A1 (en)	2015-05-04	2018-03-14	Academisch Medisch Centrum	Biomarkers for the detection of aspirin insensitivity
EP3924351B1 (en)	2019-02-12	2025-05-21	Sumitomo Pharma America, Inc.	Crystalline form of the hydrochloride salt of 2-((1r,4r)-4-((3-(3-(trifluoromethyl)phenyl) imidazo[1,2-b]pyridazin-6-yl)amino)cyclohexyl)propan-2-ol
IL305573A (en)	2021-03-15	2023-10-01	Saul Yedgar	HYALURONIC ACID-CONJUGATED DIPALMITOYL PHOSPHATIDYL ETHANOLAMINE IN COMBINATION WITH NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) FOR TREATING OR ALLEVIATING INFLAMMATORY DISEASES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3455924A (en) *	1967-02-08	1969-07-15	Upjohn Co	Dianisylimidazoles

1996
- 1996-04-02 CZ CZ973133A patent/CZ313397A3/cs unknown
- 1996-04-02 HU HU9801602A patent/HUP9801602A3/hu unknown
- 1996-04-02 EP EP96909164A patent/EP0819127A1/en not_active Withdrawn
- 1996-04-02 CA CA002216809A patent/CA2216809A1/en not_active Abandoned
- 1996-04-02 AU AU52766/96A patent/AU5276696A/en not_active Abandoned
- 1996-04-02 TR TR97/01105T patent/TR199701105T1/xx unknown
- 1996-04-02 EA EA199700209A patent/EA199700209A1/ru unknown
- 1996-04-02 JP JP8529971A patent/JPH11501049A/ja active Pending
- 1996-04-02 KR KR1019970706963A patent/KR19980703559A/ko not_active Ceased
- 1996-04-02 CN CN96194403A patent/CN1186492A/zh active Pending
- 1996-04-02 PL PL96322623A patent/PL322623A1/xx unknown
- 1996-04-02 NZ NZ304886A patent/NZ304886A/en unknown
- 1996-04-02 SK SK1332-97A patent/SK133297A3/sk unknown
- 1996-04-02 WO PCT/EP1996/001438 patent/WO1996031509A1/en not_active Ceased
1997
- 1997-09-25 IS IS4570A patent/IS4570A/is unknown
- 1997-09-30 BG BG101934A patent/BG101934A/xx unknown
- 1997-10-03 NO NO974595A patent/NO974595L/no unknown

Also Published As

Publication number	Publication date
TR199701105T1 (xx)	1998-02-21
PL322623A1 (en)	1998-02-02
NO974595D0 (no)	1997-10-03
MX9707379A (es)	1997-11-29
WO1996031509A1 (en)	1996-10-10
KR19980703559A (ko)	1998-11-05
JPH11501049A (ja)	1999-01-26
EP0819127A1 (en)	1998-01-21
SK133297A3 (en)	1998-07-08
CA2216809A1 (en)	1996-10-10
NZ304886A (en)	1998-11-25
NO974595L (no)	1997-12-03
HUP9801602A3 (en)	1999-01-28
CZ313397A3 (cs)	1998-03-18
IS4570A (is)	1997-09-25
CN1186492A (zh)	1998-07-01
BG101934A (en)	1999-04-30
HUP9801602A2 (hu)	1998-11-30
AU5276696A (en)	1996-10-23

Publication	Publication Date	Title
EA199700209A1 (ru)	1998-04-30	ПРОИЗВОДНЫЕ ИМИДАЗО[1,2-a]ПИРИДИНА
EA199800907A1 (ru)	1999-04-29	Производные карболина
EA200200873A1 (ru)	2003-04-24	Новые пиперазиновые производные
PL145087B1 (en)	1988-08-31	Method of obtaining novel derivatives of imidazo /1,5-a/ pyridine
EA200001224A1 (ru)	2001-08-27	Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
EA200001223A1 (ru)	2001-10-22	Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
EA200000759A1 (ru)	2001-04-23	Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
EA199900853A1 (ru)	2000-10-30	Замещенные производные бензопирана для лечения воспалительных процессов
ME00768B (me)	2011-10-10	Derivati supstituisanih benzol sulfonamida kao pro-lekovi cox-2 inhibitora
EA200000723A1 (ru)	2001-04-23	Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
CA2238875A1 (en)	1997-06-26	Tri-aryl ethane derivatives as pde iv inhibitors
EA199700160A1 (ru)	1998-02-26	Производные индола в качестве антагонистов eaa
EA200000741A1 (ru)	2001-02-26	Новые производные дигидроксигексановой кислоты
DK0746545T3 (da)	1999-11-08	Nipecotinsyrederivater som antithrombotiske forbindelser
NZ330244A (en)	2000-01-28	Isoxazole derivatives useful in the treatment of inflammatory diseases
EA200200883A1 (ru)	2003-04-24	Производные пирано[2,3-с]имидазо[1,2-а]пиридина для лечения заболеваний желудочно-кишечного тракта
EA199800701A1 (ru)	1999-02-25	БЕНЗО[С]ХИНОЛИЗИНОВЫЕ ПРОИЗВОДНЫЕ, ИХ ПОЛУЧЕНИЕ И ИСПОЛЬЗОВАНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ 5a-РЕДУКТАЗ
EP0842933A4 (en)	2001-04-04	NAPHTHYRIDINE DERIVATIVES.
FR2395998A1 (fr)	1979-01-26	Nouveaux derives de la thiazolidine et leur application dans le traitement de l'hypertension
EA200000448A1 (ru)	2000-10-30	Новые полиморфные формы ципамфиллина
EA200000205A1 (ru)	2000-10-30	Производные пирролопирролона в качестве ингибиторов эластазы нейтрофилов
FR2618436B1 (fr)	1989-10-27	Derives de piperidine, leur preparation et leur application en therapeutique
GR1000887B (el)	1993-03-16	Νεα παραγωγα σπιροφουρανης.
FI884017A0 (fi)	1988-08-31	Pyrrolo /1,2-a/ imidazol- och imidazo /1,2-a/-pyridinderivat och anvaendning daerav som inhibitorer av 5-lipoxigenasstigen.
DE3566263D1 (de)	1988-12-22	Novel cyanoimidazole nucleoside derivatives