EA006608B1 - Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов - Google Patents
Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов Download PDFInfo
- Publication number
- EA006608B1 EA006608B1 EA200301167A EA200301167A EA006608B1 EA 006608 B1 EA006608 B1 EA 006608B1 EA 200301167 A EA200301167 A EA 200301167A EA 200301167 A EA200301167 A EA 200301167A EA 006608 B1 EA006608 B1 EA 006608B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- alkyl
- halogen
- different meanings
- group
- halogen atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123952A DE10123952A1 (de) | 2001-05-17 | 2001-05-17 | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| PCT/EP2002/005338 WO2002100411A1 (en) | 2001-05-17 | 2002-05-15 | Naphtothiazine positive allosteric ampa receptor modulators (paarm) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200301167A1 EA200301167A1 (ru) | 2004-06-24 |
| EA006608B1 true EA006608B1 (ru) | 2006-02-24 |
Family
ID=7685080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200301167A EA006608B1 (ru) | 2001-05-17 | 2002-05-15 | Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1404340A1 (de) |
| JP (1) | JP2004529980A (de) |
| KR (1) | KR20040007572A (de) |
| CN (1) | CN1533278A (de) |
| AR (1) | AR036332A1 (de) |
| BG (1) | BG108324A (de) |
| BR (1) | BR0209796A (de) |
| CA (1) | CA2449189A1 (de) |
| CO (1) | CO5550460A2 (de) |
| CZ (1) | CZ20033112A3 (de) |
| DE (1) | DE10123952A1 (de) |
| EA (1) | EA006608B1 (de) |
| EC (1) | ECSP034852A (de) |
| EE (1) | EE200300566A (de) |
| HR (1) | HRP20030933A2 (de) |
| HU (1) | HUP0401273A3 (de) |
| IL (1) | IL158642A0 (de) |
| MX (1) | MXPA03010373A (de) |
| NO (1) | NO20035088D0 (de) |
| NZ (1) | NZ530154A (de) |
| PL (1) | PL364053A1 (de) |
| SK (1) | SK14222003A3 (de) |
| UY (1) | UY27290A1 (de) |
| WO (1) | WO2002100411A1 (de) |
| YU (1) | YU90403A (de) |
| ZA (1) | ZA200308466B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101600436A (zh) * | 2006-08-31 | 2009-12-09 | 艾伯塔大学校董 | 使用正变构ampa受体调节剂抑制呼吸抑制的方法 |
| CN111518058B (zh) * | 2020-05-29 | 2021-03-09 | 四川大学华西医院 | 一种噁噻嗪类化合物及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998012185A1 (en) * | 1996-09-17 | 1998-03-26 | The Regents Of The University Of California | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
| WO1999067242A1 (en) * | 1998-06-25 | 1999-12-29 | Merck & Co., Inc. | Naphtho[1,8-de]thiasin-2-yl methyl carbapenem antibacterials |
| DE10004572A1 (de) * | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
-
2001
- 2001-05-17 DE DE10123952A patent/DE10123952A1/de not_active Withdrawn
-
2002
- 2002-05-15 EA EA200301167A patent/EA006608B1/ru not_active IP Right Cessation
- 2002-05-15 CA CA002449189A patent/CA2449189A1/en not_active Abandoned
- 2002-05-15 SK SK1422-2003A patent/SK14222003A3/sk unknown
- 2002-05-15 CN CNA028100832A patent/CN1533278A/zh active Pending
- 2002-05-15 EE EEP200300566A patent/EE200300566A/xx unknown
- 2002-05-15 KR KR10-2003-7014965A patent/KR20040007572A/ko not_active Withdrawn
- 2002-05-15 UY UY27290A patent/UY27290A1/es not_active Application Discontinuation
- 2002-05-15 MX MXPA03010373A patent/MXPA03010373A/es unknown
- 2002-05-15 HR HR20030933A patent/HRP20030933A2/xx not_active Application Discontinuation
- 2002-05-15 BR BR0209796-6A patent/BR0209796A/pt not_active IP Right Cessation
- 2002-05-15 IL IL15864202A patent/IL158642A0/xx unknown
- 2002-05-15 YU YU90403A patent/YU90403A/sh unknown
- 2002-05-15 NZ NZ530154A patent/NZ530154A/en unknown
- 2002-05-15 JP JP2003503232A patent/JP2004529980A/ja not_active Abandoned
- 2002-05-15 EP EP02750931A patent/EP1404340A1/de not_active Withdrawn
- 2002-05-15 CZ CZ20033112A patent/CZ20033112A3/cs unknown
- 2002-05-15 HU HU0401273A patent/HUP0401273A3/hu unknown
- 2002-05-15 WO PCT/EP2002/005338 patent/WO2002100411A1/en not_active Ceased
- 2002-05-15 PL PL02364053A patent/PL364053A1/xx not_active Application Discontinuation
- 2002-05-17 AR ARP020101827A patent/AR036332A1/es unknown
-
2003
- 2003-10-30 ZA ZA200308466A patent/ZA200308466B/en unknown
- 2003-11-07 BG BG108324A patent/BG108324A/bg unknown
- 2003-11-14 NO NO20035088A patent/NO20035088D0/no not_active Application Discontinuation
- 2003-11-17 EC EC2003004852A patent/ECSP034852A/es unknown
- 2003-12-01 CO CO03105591A patent/CO5550460A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| UY27290A1 (es) | 2002-12-31 |
| ECSP034852A (es) | 2003-12-24 |
| BR0209796A (pt) | 2004-06-01 |
| KR20040007572A (ko) | 2004-01-24 |
| YU90403A (sh) | 2006-05-25 |
| BG108324A (bg) | 2004-12-30 |
| MXPA03010373A (es) | 2004-03-16 |
| WO2002100411A1 (en) | 2002-12-19 |
| EA200301167A1 (ru) | 2004-06-24 |
| NZ530154A (en) | 2005-09-30 |
| AR036332A1 (es) | 2004-09-01 |
| EE200300566A (et) | 2004-02-16 |
| CN1533278A (zh) | 2004-09-29 |
| CZ20033112A3 (en) | 2004-03-17 |
| SK14222003A3 (sk) | 2004-05-04 |
| DE10123952A1 (de) | 2002-11-21 |
| HUP0401273A3 (en) | 2006-11-28 |
| CA2449189A1 (en) | 2002-12-19 |
| HUP0401273A2 (hu) | 2004-10-28 |
| NO20035088L (no) | 2003-11-14 |
| JP2004529980A (ja) | 2004-09-30 |
| ZA200308466B (en) | 2004-05-24 |
| IL158642A0 (en) | 2004-05-12 |
| PL364053A1 (en) | 2004-12-13 |
| HRP20030933A2 (en) | 2004-04-30 |
| CO5550460A2 (es) | 2005-08-31 |
| EP1404340A1 (de) | 2004-04-07 |
| NO20035088D0 (no) | 2003-11-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |