DZ2979A1 - Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant. - Google Patents

Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant.

Info

Publication number: DZ2979A1
Authority: DZ; Algeria
Prior art keywords: ccr5; pharmaceutical compositions; compositions containing; modulator compounds; novel chemokine
Prior art date: 1998-12-23

Application number

DZ990279A

Other languages

English (en)

Inventor

Duncan Robert Armour

Blanda Luzia Christa Stammen

Manoussos Perros

David Anthony Price

Anthony Wood

Martin Paul Edwards

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-23

Filing date

1999-12-22

Publication date

2005-01-30

1998-12-23 Priority claimed from GBGB9828420.1A external-priority patent/GB9828420D0/en

1999-09-10 Priority claimed from GBGB9921375.3A external-priority patent/GB9921375D0/en

1999-12-22 Application filed by Pfizer filed Critical Pfizer

2001-11-19 Priority to DZ010081A priority Critical patent/DZ3326A1/fr

2005-01-30 Application granted granted Critical

2005-01-30 Publication of DZ2979A1 publication Critical patent/DZ2979A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

DZ990279A 1998-12-23 1999-12-22 Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant. DZ2979A1 (fr)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DZ010081A DZ3326A1 (fr)	1998-12-23	2001-11-19	Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant.

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9828420.1A GB9828420D0 (en)	1998-12-23	1998-12-23	CCR5 antagonists useful as anti-hiv agents
GBGB9921375.3A GB9921375D0 (en)	1999-09-10	1999-09-10	CCR5 Modulators

Publications (1)

Publication Number	Publication Date
DZ2979A1 true DZ2979A1 (fr)	2005-01-30

Family

ID=26314899

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DZ990279A DZ2979A1 (fr)	1998-12-23	1999-12-22	Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant.
DZ010081A DZ3326A1 (fr)	1998-12-23	2001-11-19	Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DZ010081A DZ3326A1 (fr)	1998-12-23	2001-11-19	Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant.

Country Status (48)

Country	Link
US (1)	US6586430B1 (fr)
EP (1)	EP1140085B1 (fr)
JP (1)	JP3602795B2 (fr)
KR (1)	KR100425612B1 (fr)
CN (1)	CN1331591A (fr)
AP (1)	AP1697A (fr)
AR (1)	AR024233A1 (fr)
AT (1)	ATE505190T1 (fr)
AU (1)	AU763644B2 (fr)
BG (1)	BG65448B1 (fr)
BR (1)	BRPI9917007B8 (fr)
CA (1)	CA2350073C (fr)
CO (1)	CO5300387A1 (fr)
CR (2)	CR9879A (fr)
CU (1)	CU23344A3 (fr)
CY (1)	CY1111504T1 (fr)
CZ (1)	CZ300926B6 (fr)
DE (1)	DE69943352D1 (fr)
DK (1)	DK1140085T3 (fr)
DZ (2)	DZ2979A1 (fr)
EA (1)	EA004988B1 (fr)
EE (1)	EE05170B1 (fr)
EG (1)	EG24400A (fr)
GC (1)	GC0000117A (fr)
GE (1)	GEP20033131B (fr)
HK (1)	HK1039902A1 (fr)
HR (2)	HRP20120132B1 (fr)
HU (1)	HU228754B1 (fr)
ID (1)	ID28965A (fr)
IL (2)	IL143512A0 (fr)
IS (1)	IS5944A (fr)
MA (1)	MA26714A1 (fr)
ME (1)	ME00513B (fr)
NO (1)	NO330677B1 (fr)
NZ (1)	NZ511794A (fr)
OA (1)	OA11735A (fr)
PA (1)	PA8487201A1 (fr)
PE (1)	PE20001420A1 (fr)
PL (1)	PL201875B1 (fr)
PT (1)	PT1140085E (fr)
RS (1)	RS51701B (fr)
SI (1)	SI1140085T1 (fr)
SK (1)	SK287020B6 (fr)
TN (1)	TNSN99252A1 (fr)
TR (1)	TR200101793T2 (fr)
TW (1)	TW577888B (fr)
UA (1)	UA72750C2 (fr)
WO (1)	WO2000038680A1 (fr)

Families Citing this family (70)

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GB2359078A (en)	2000-02-11	2001-08-15	Astrazeneca Uk Ltd	Pharmaceutically active pyrimidine derivatives
GB2359081A (en)	2000-02-11	2001-08-15	Astrazeneca Uk Ltd	Pharmaceutically active thiazolopyrimidines
GB2359551A (en)	2000-02-23	2001-08-29	Astrazeneca Uk Ltd	Pharmaceutically active pyrimidine derivatives
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SE0003828D0 (sv)	2000-10-20	2000-10-20	Astrazeneca Ab	Novel compounds
CA2432527A1 (fr) *	2000-12-22	2002-07-04	Takeda Chemical Industries, Ltd.	Compositions medicinales s'administrant par voie orale
SE0101322D0 (sv)	2001-04-12	2001-04-12	Astrazeneca Ab	Novel compounds
SE0103818D0 (sv) *	2001-11-15	2001-11-15	Astrazeneca Ab	Chemical compounds
TW200305395A (en) *	2002-03-15	2003-11-01	Novartis Ag	Organic compounds
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JP2005533999A (ja) *	2002-05-23	2005-11-10	ファイザー・インク	受容体滞留時間を測定するリガンドの同定方法
GB0221828D0 (en)	2002-09-20	2002-10-30	Astrazeneca Ab	Novel compound
US7202259B2 (en)	2002-11-18	2007-04-10	Euro-Celtique S.A.	Therapeutic agents useful for treating pain
WO2004052862A1 (fr) *	2002-12-10	2004-06-24	Ono Pharmaceutical Co., Ltd.	Composes heterocycliques contenant de l'azote et leur utilisation medicale
AU2003300902A1 (en) *	2002-12-13	2004-07-09	Smithkline Beecham Corporation	Piperidine derivatives as CCR5 antagonists
ATE384724T1 (de)	2002-12-13	2008-02-15	Smithkline Beecham Corp	Cyclopropylverbindungen als ccr5 antagonisten
WO2004080966A1 (fr)	2003-03-14	2004-09-23	Ono Pharmaceutical Co., Ltd.	Derives heterocycliques renfermant de l'azote et medicaments contenant ces derives comme principe actif
WO2004092169A1 (fr)	2003-04-18	2004-10-28	Ono Pharmaceutical Co., Ltd.	Compose de spiropiperidine et son utilisation medicinale
EP1654229B1 (fr) *	2003-07-31	2007-05-09	AstraZeneca AB	Derives de piperidine en tant que modulateurs du recepteur ccr5
US7220772B2 (en)	2003-09-05	2007-05-22	Pfizer, Inc.	Pyrazole derivatives
CA2579609A1 (fr)	2003-09-10	2005-03-17	Virochem Pharma Inc.	Composes de spirohydantoine et procedes de modulation de l'activite des recepteurs de chimiokine
OA13266A (en) *	2003-10-03	2007-01-31	Pfizer	Imidazopyridine substituted tropane derivatives with CCR5 receptor antagonist activity for the treatment of HIV and inflammation.
GB0323236D0 (en) *	2003-10-03	2003-11-05	Pfizer Ltd	Chemical compounds
GB0328243D0 (en)	2003-12-05	2004-01-07	Astrazeneca Ab	Methods
CA2552087C (fr) *	2004-01-30	2011-01-25	Euro-Celtique S.A.	Procedes d'elaboration de composes de 4-tetrazolyl-4-phenylpiperidine
TW200533348A (en)	2004-02-18	2005-10-16	Theravance Inc	Indazole-carboxamide compounds as 5-ht4 receptor agonists
BRPI0509853A (pt) *	2004-04-14	2007-10-09	Pfizer	compostos de imidazol ligados a enxofre para o tratamento de hiv
TW200610761A (en) *	2004-04-23	2006-04-01	Astrazeneca Ab	Chemical compounds
PL1761542T3 (pl)	2004-06-09	2008-06-30	Hoffmann La Roche	Pochodne oktahydropirolo[3,4-c]pirolu i ich zastosowanie jako środków przeciwwirusowych
PE20090123A1 (es)	2004-09-13	2009-03-10	Ono Pharmaceutical Co	Un derivado heterociclico conteniendo nitrogeno y un farmaco conteniendo el mismo como el ingrediente activo
WO2006108790A1 (fr) *	2005-04-08	2006-10-19	Neurosearch A/S	(+) - and (-) -8-alkyle-3-(trifluoralkylsulfonyloxy)-8-azabicycle (3.2.1.)oct-2-ene
EP1879894A1 (fr)	2005-04-14	2008-01-23	F.Hoffmann-La Roche Ag	Derives aminopyrazole, leur fabrication et leur utilisation comme agents pharmaceutiques
WO2006129679A1 (fr)	2005-05-31	2006-12-07	Ono Pharmaceutical Co., Ltd.	Compose de spiropiperidine et son utilisation medicinale
US7665658B2 (en)	2005-06-07	2010-02-23	First Data Corporation	Dynamic aggregation of payment transactions
ES2277745B1 (es) *	2005-06-14	2008-06-01	Laboratorios Almirall S.A.	Derivados n-amida de 8-azabiciclo /3.2.1/oct-3-ilo como antagonistas de ccr1.
ES2427989T3 (es)	2005-10-28	2013-11-05	Ono Pharmaceutical Co., Ltd.	Compuesto que contiene un grupo básico y uso del mismo
ES2407115T3 (es)	2005-11-18	2013-06-11	Ono Pharmaceutical Co., Ltd.	Compuesto que contiene un grupo básico y uso del mismo
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1999
- 1999-11-29 PE PE1999001190A patent/PE20001420A1/es not_active IP Right Cessation
- 1999-11-30 AR ARP990106086A patent/AR024233A1/es active IP Right Grant
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Also Published As

Publication number	Publication date
ID28965A (id)	2001-07-19
HUP0104795A2 (hu)	2002-04-29
SK8752001A3 (en)	2003-02-04
ME00513B (fr)	2011-10-10
BR9917007A (pt)	2001-10-30
CA2350073A1 (fr)	2000-07-06
BG105721A (en)	2002-02-28
HUP0104795A3 (en)	2002-05-28
IL143512A0 (en)	2002-04-21
EA200100589A1 (ru)	2002-02-28
PL201875B1 (pl)	2009-05-29
TNSN99252A1 (fr)	2005-11-10
BRPI9917007B8 (pt)	2021-05-25
HRP20120132A8 (hr)	2017-11-03
OA11735A (en)	2005-05-12
NO330677B1 (no)	2011-06-06
AU1675100A (en)	2000-07-31
HK1039902A1 (zh)	2002-05-17
AR024233A1 (es)	2002-09-25
BRPI9917007B1 (pt)	2016-07-26
WO2000038680A1 (fr)	2000-07-06
RS51701B (sr)	2011-10-31
US6586430B1 (en)	2003-07-01
PL349495A1 (en)	2002-07-29
JP2002533393A (ja)	2002-10-08
CA2350073C (fr)	2007-04-17
CR6392A (es)	2006-08-09
SI1140085T1 (sl)	2011-08-31
TR200101793T2 (tr)	2001-12-21
CU23344A3 (es)	2009-02-20
ATE505190T1 (de)	2011-04-15
AP1697A (en)	2006-12-22
NO20013183L (no)	2001-08-08
DE69943352D1 (de)	2011-05-26
YU38801A (sh)	2005-06-10
DZ3326A1 (fr)	2005-05-29
MA26714A1 (fr)	2004-12-20
EG24400A (en)	2009-04-29
UA72750C2 (en)	2005-04-15
CR9879A (es)	2008-06-20
SK287020B6 (sk)	2009-09-07
PE20001420A1 (es)	2000-12-18
KR20010089701A (ko)	2001-10-08
AU763644B2 (en)	2003-07-31
HRP20120132B1 (hr)	2018-01-26
GEP20033131B (en)	2003-12-25
IL143512A (en)	2013-06-27
HRP20010468B1 (hr)	2012-06-30
EP1140085B1 (fr)	2011-04-13
JP3602795B2 (ja)	2004-12-15
AP2001002186A0 (en)	2001-06-30
NO20013183D0 (no)	2001-06-25
NZ511794A (en)	2003-10-31
PA8487201A1 (es)	2002-02-21
EA004988B1 (ru)	2004-10-28
TW577888B (en)	2004-03-01
PT1140085E (pt)	2011-06-16
KR100425612B1 (ko)	2004-04-01
HU228754B1 (en)	2013-05-28
GC0000117A (en)	2005-06-29
CZ300926B6 (cs)	2009-09-09
BG65448B1 (bg)	2008-08-29
CY1111504T1 (el)	2015-08-05
DK1140085T3 (da)	2011-06-27
CZ20012298A3 (cs)	2002-09-11
EE05170B1 (et)	2009-06-15
EE200100345A (et)	2002-12-16
EP1140085A1 (fr)	2001-10-10
HRP20010468A2 (en)	2003-02-28
CN1331591A (zh)	2002-01-16
IS5944A (is)	2001-05-15
HRP20120132A2 (hr)	2012-03-31
CO5300387A1 (es)	2003-07-31

Publication	Publication Date	Title
DZ3326A1 (fr)	2005-05-29	Composés nouveaux modulateurs de chimiokine ccr5, et compositions pharmaceutiques les contenant.
DZ2978A1 (fr)	2004-07-04	Composés chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant.
DZ2964A1 (fr)	2004-03-15	Diphénylurées substituées nouvelles, et compositions pharmaceutiques les contenant.
DZ2086A1 (fr)	2002-07-22	Benzylaminopipéridines substituées et compositionspharmaceutiques les contenant.
DZ2594A1 (fr)	2003-02-22	Dérivés de 2-aminopyridine nouveaux et compositions pharmaceutiques les contenant.
DZ2887A1 (fr)	2003-12-15	Dérivés d'azétidine, leur préparation et les médicaments les contenant.
MA24529A1 (fr)	1998-12-31	Pyrazolopyrimidinones nouvelles, procede pour leur preparation et compositions les contenant .
FR2715847B1 (fr)	1996-04-12	Composition contenant des acides nucléiques, préparation et utilisations.
MA26490A1 (fr)	2004-12-20	Derives de tetrahydroisoquinoleine nouveaux, procedes pour leur preparation et compositions pharmaceutiques les contenant.
MA26551A1 (fr)	2004-12-20	Agonistes de prostaglandines nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
DZ2890A1 (fr)	2003-12-15	4-Carboxamino-2-substitué-1,2,3,4-tétrahydroquinoléines, procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ2461A1 (fr)	2003-01-18	Dérivés d'arylkylamines nouveaux et composition pharmaceutiques les contenant.
FR2732967B1 (fr)	1997-07-04	1-phenylpyrazole-3-carboxamides substitues, actifs sur la neurotensine, leur preparation, les compositions pharmaceutiques en contenant
DZ2009A1 (fr)	2002-10-23	Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
DZ2745A1 (fr)	2003-09-08	BicycloÄ2.2.1Üheptanes nouveaux procédé pour leur préparation et compositions pharmaceutiques les contenant.
DZ3191A1 (fr)	2001-01-11	Composés d'indazole et compositions pharmaceutiques inhibant les protéines kinases, et procédés d'utilisation de ceux-ci.
MA26472A1 (fr)	2004-12-20	Derives de n-hydroxy-b-sulfonylpropionamide, procede pour leur preparation et compositions pharmaceutiques les contenant.
MA26630A1 (fr)	2004-12-20	4-phenylpyperidines nouvelles, procede pour leur preparation et compositions pharmaceutiques les contenant
DZ2479A1 (fr)	2003-02-01	Composés inhibiteurs sélectifs de cox-2 anti-inflammatoires et compositions pharmaceutiques les contenant.
CH689805A8 (fr)	2000-02-29	Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
DZ2188A1 (fr)	2002-12-02	Dérivés de quinoxalinedone, procédés et intermédiaires pour leur préparation et compositions pharmaceutiques les contenant.
MA26558A1 (fr)	2004-12-20	Derives nouveaux de 6-0-methylerythromycine a, procede pour leur preparation et compositions pharmaceutiques les contenant.
MA26514A1 (fr)	2004-12-20	Agonistes de prostaglandines, procede pour leur preparation et compositions pharmaceutiques les contenant.
MA26707A1 (fr)	2004-12-20	Azalides nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
DZ2155A1 (fr)	2002-10-26	Aazétidines, procédé pour leur préparation, et co mpositions pharmaceutiques les contenant.