DZ2642A1 - Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ. - Google Patents

Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ.

Info

Publication number: DZ2642A1
Authority: DZ; Algeria
Prior art keywords: spiroäisobenzufuran; piperidineü; butylü; 3ylü; fluorphenyl
Prior art date: 1997-11-07

Application number

DZ980252A

Other languages

English (en)

Inventor

Niels Mark

Heidi Lopez De Diego

Ole Nielsen

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-07

Filing date

1998-11-04

Publication date

2004-12-28

1998-11-04 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2004-12-28 Application granted granted Critical

2004-12-28 Publication of DZ2642A1 publication Critical patent/DZ2642A1/fr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Psychology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DZ980252A 1997-11-07 1998-11-04 Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ. DZ2642A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK126797		1997-11-07

Publications (1)

Publication Number	Publication Date
DZ2642A1 true DZ2642A1 (fr)	2004-12-28

Family

ID=8102935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ980252A DZ2642A1 (fr)	1997-11-07	1998-11-04	Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ.

Country Status (38)

Country	Link
US (2)	US6844352B2 (fr)
EP (1)	EP1044202B1 (fr)
JP (1)	JP3605358B2 (fr)
KR (1)	KR100399274B1 (fr)
CN (1)	CN1105115C (fr)
AR (1)	AR023010A1 (fr)
AT (1)	ATE288918T1 (fr)
AU (1)	AU749094B2 (fr)
BG (1)	BG64906B1 (fr)
BR (1)	BR9813949A (fr)
CA (1)	CA2308745C (fr)
CZ (1)	CZ288666B6 (fr)
DE (1)	DE69828999T2 (fr)
DZ (1)	DZ2642A1 (fr)
EA (1)	EA002092B1 (fr)
EG (1)	EG23791A (fr)
ES (1)	ES2234162T3 (fr)
HR (1)	HRP20000261B1 (fr)
HU (1)	HUP0100991A3 (fr)
ID (1)	ID25776A (fr)
IL (1)	IL135723A (fr)
IS (1)	IS2342B (fr)
JO (1)	JO2052B1 (fr)
MA (1)	MA25585A1 (fr)
NO (1)	NO325920B1 (fr)
NZ (1)	NZ504065A (fr)
PE (1)	PE130299A1 (fr)
PL (1)	PL190538B1 (fr)
PT (1)	PT1044202E (fr)
RS (1)	RS49777B (fr)
SK (1)	SK285245B6 (fr)
TN (1)	TNSN98201A1 (fr)
TR (1)	TR200001267T2 (fr)
TW (1)	TW483894B (fr)
UA (1)	UA64769C2 (fr)
UY (1)	UY25236A1 (fr)
WO (1)	WO1999024436A1 (fr)
ZA (1)	ZA9810116B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR030453A1 (es) *	2000-08-15	2003-08-20	Lundbeck & Co As H	Composicion farmaceutica con contenido de 1' [4-[1-(4-fluorofenil)-1h-indol-3-il]-1-butil] espiro [isobenzofuran-1 (3h), 4'-piperidina]
AU2003263155A1 (en) *	2002-09-20	2004-04-08	H. Lundbeck A/S	Method for manufacture of dihydroisobenzofuran derivatives
US7863272B2 (en)	2003-06-12	2011-01-04	M's Science Corporation	Sigma ligands for neuronal regeneration and functional recovery
WO2007012319A1 (fr) *	2005-07-29	2007-02-01	Sigma-Aldrich Production Gmbh	Melanges lc/ms contenant des additifs ionisants
JP2009512711A (ja)	2005-10-21	2009-03-26	ブレインセルス，インコーポレイティド	Ｐｄｅ阻害による神経新生の調節
JP2009513672A (ja)	2005-10-31	2009-04-02	ブレインセルス，インコーポレイティド	神経発生のｇａｂａ受容体媒介調節
US20070244143A1 (en) *	2006-03-08	2007-10-18	Braincells, Inc	Modulation of neurogenesis by nootropic agents
US20100216734A1 (en) *	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
WO2007134077A2 (fr) *	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenèse induite par le récepteur 5ht
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
AU2007249399A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
MX2009002496A (es) *	2006-09-08	2009-07-10	Braincells Inc	Combinaciones que contienen un derivado de 4-acilaminopiridina.
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
AU2007299920A1 (en) *	2006-09-19	2008-03-27	Braincells, Inc.	PPAR Mediated Modulation of Neurogenesis
WO2010099217A1 (fr)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5109002A (en) *	1989-09-08	1992-04-28	Du Pont Merck Pharmaceutical Company	Antipsychotic 1-cycloalkylpiperidines
NZ243065A (en) *	1991-06-13	1995-07-26	Lundbeck & Co As H	Piperidine derivatives and pharmaceutical compositions

1998
- 1998-06-11 UA UA2000052828A patent/UA64769C2/uk unknown
- 1998-10-20 TW TW087117299A patent/TW483894B/zh not_active IP Right Cessation
- 1998-10-27 MA MA25316A patent/MA25585A1/fr unknown
- 1998-11-03 EG EG136298A patent/EG23791A/xx active
- 1998-11-04 TN TNTNSN98201A patent/TNSN98201A1/fr unknown
- 1998-11-04 DZ DZ980252A patent/DZ2642A1/fr active
- 1998-11-05 PE PE1998001067A patent/PE130299A1/es not_active Application Discontinuation
- 1998-11-05 AR ARP980105596A patent/AR023010A1/es active IP Right Grant
- 1998-11-05 JO JO19982052A patent/JO2052B1/en active
- 1998-11-05 ZA ZA9810116A patent/ZA9810116B/xx unknown
- 1998-11-06 EA EA200000502A patent/EA002092B1/ru not_active IP Right Cessation
- 1998-11-06 CN CN98810910A patent/CN1105115C/zh not_active Expired - Fee Related
- 1998-11-06 BR BR9813949-5A patent/BR9813949A/pt not_active Application Discontinuation
- 1998-11-06 HR HR20000261A patent/HRP20000261B1/xx not_active IP Right Cessation
- 1998-11-06 AT AT98952580T patent/ATE288918T1/de not_active IP Right Cessation
- 1998-11-06 ES ES98952580T patent/ES2234162T3/es not_active Expired - Lifetime
- 1998-11-06 SK SK646-2000A patent/SK285245B6/sk not_active IP Right Cessation
- 1998-11-06 RS YUP-235/00A patent/RS49777B/sr unknown
- 1998-11-06 PT PT98952580T patent/PT1044202E/pt unknown
- 1998-11-06 NZ NZ504065A patent/NZ504065A/en unknown
- 1998-11-06 IL IL13572398A patent/IL135723A/xx not_active IP Right Cessation
- 1998-11-06 KR KR10-2000-7004858A patent/KR100399274B1/ko not_active Expired - Fee Related
- 1998-11-06 DE DE69828999T patent/DE69828999T2/de not_active Expired - Fee Related
- 1998-11-06 CZ CZ20001663A patent/CZ288666B6/cs not_active IP Right Cessation
- 1998-11-06 AU AU10226/99A patent/AU749094B2/en not_active Ceased
- 1998-11-06 EP EP98952580A patent/EP1044202B1/fr not_active Expired - Lifetime
- 1998-11-06 UY UY25236A patent/UY25236A1/es not_active IP Right Cessation
- 1998-11-06 HU HU0100991A patent/HUP0100991A3/hu unknown
- 1998-11-06 WO PCT/DK1998/000480 patent/WO1999024436A1/fr not_active Ceased
- 1998-11-06 JP JP2000520446A patent/JP3605358B2/ja not_active Expired - Fee Related
- 1998-11-06 ID IDW20000997D patent/ID25776A/id unknown
- 1998-11-06 CA CA002308745A patent/CA2308745C/fr not_active Expired - Fee Related
- 1998-11-06 TR TR2000/01267T patent/TR200001267T2/xx unknown
- 1998-11-06 PL PL98340220A patent/PL190538B1/pl not_active IP Right Cessation
2000
- 2000-04-18 IS IS5460A patent/IS2342B/is unknown
- 2000-04-27 NO NO20002188A patent/NO325920B1/no not_active IP Right Cessation
- 2000-05-29 BG BG104485A patent/BG64906B1/bg unknown
2002
- 2002-10-15 US US10/272,403 patent/US6844352B2/en not_active Expired - Fee Related
2004
- 2004-12-13 US US11/012,084 patent/US20050171135A1/en not_active Abandoned

Also Published As

Publication number	Publication date
IL135723A (en)	2005-11-20
JP2001522852A (ja)	2001-11-20
RS49777B (sr)	2008-06-05
EA200000502A1 (ru)	2000-10-30
JO2052B1 (en)	1999-05-15
DE69828999D1 (de)	2005-03-17
KR20010031791A (ko)	2001-04-16
ID25776A (id)	2000-11-02
EP1044202B1 (fr)	2005-02-09
KR100399274B1 (ko)	2003-09-26
HRP20000261B1 (en)	2009-04-30
HUP0100991A3 (en)	2003-03-28
UY25236A1 (es)	2000-12-29
CN1105115C (zh)	2003-04-09
CN1278823A (zh)	2001-01-03
DE69828999T2 (de)	2005-07-21
SK6462000A3 (en)	2000-10-09
CZ288666B6 (cs)	2001-08-15
HRP20000261A2 (en)	2001-04-30
EP1044202A1 (fr)	2000-10-18
US6844352B2 (en)	2005-01-18
YU23500A (sh)	2003-12-31
PL190538B1 (pl)	2005-12-30
TW483894B (en)	2002-04-21
ATE288918T1 (de)	2005-02-15
EA002092B1 (ru)	2001-12-24
PT1044202E (pt)	2005-04-29
ES2234162T3 (es)	2005-06-16
IS5460A (is)	2000-04-18
TR200001267T2 (tr)	2000-09-21
UA64769C2 (uk)	2004-03-15
IS2342B (is)	2008-02-15
BR9813949A (pt)	2000-09-26
NO20002188L (no)	2000-06-14
BG64906B1 (bg)	2006-08-31
EG23791A (en)	2007-08-13
TNSN98201A1 (fr)	2005-03-15
AU1022699A (en)	1999-05-31
PL340220A1 (en)	2001-01-15
SK285245B6 (sk)	2006-09-07
ZA9810116B (en)	1999-05-07
IL135723A0 (en)	2001-05-20
MA25585A1 (fr)	2002-12-31
CA2308745A1 (fr)	1999-05-20
AU749094B2 (en)	2002-06-20
BG104485A (en)	2001-01-31
PE130299A1 (es)	1999-12-16
NZ504065A (en)	2002-05-31
WO1999024436A1 (fr)	1999-05-20
HUP0100991A2 (hu)	2001-09-28
JP3605358B2 (ja)	2004-12-22
NO325920B1 (no)	2008-08-18
CZ20001663A3 (cs)	2000-10-11
HK1034075A1 (en)	2001-10-12
CA2308745C (fr)	2004-01-20
NO20002188D0 (no)	2000-04-27
US20050171135A1 (en)	2005-08-04
US20030055074A1 (en)	2003-03-20
AR023010A1 (es)	2002-09-04

Publication	Publication Date	Title
SV1996000005A (es)	1997-03-11	Quinazolinonas bisustituidas en 2,8
IS4963A (is)	1999-01-29	Setnar 6,5-heteró-bísýklískar afleiður
TR199800444A3 (tr)	1998-10-21	Hipolipidemik 1,4-benzotiazepin-1,1-diyoksitler.
NO2006016I1 (no)	2006-11-27	7,8,9,10-tetrahydro-6H-6,10-metanoazepinoÄ4,5-gÜkinoksalintartrat
PT993456E (pt)	2005-01-31	4,5-diaril-imidazoles 2-substituidos
PT901487E (pt)	2003-08-29	4(3h)-quinazolinonas 2,3,6-trissubstituidas
NL300150I2 (nl)	2004-09-01	4 "-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten.
TR199800815A3 (tr)	1998-11-23	Sülfonilaminokarbonasitler.
TR199601002A1 (tr)	1997-08-21	2-Okzo- ve 2-thio-1, 2-dihidrokinolinil-oksazolidinonlar.
TR28098A (tr)	1996-01-08	1,2,4-okzadiazol türevleri.
TR27961A (tr)	1995-11-06	Sübstitüe edilmis 1,2,3,4 -tetrahidro-5-nitro-pirimidinler.
ID21413A (id)	1999-06-10	Turunan-turunan 1,3,8,-triaza-spiro (4,5) dekan-4-on
DK1015467T3 (da)	2004-05-03	6,9-brobundne erythromycinderivater
TR199800988A3 (tr)	1998-12-21	5' Deoksi-Sitidin türevleri.
DZ2642A1 (fr)	2004-12-28	Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ.
DE69814441D1 (de)	2003-06-12	6,11-verbrückte erythromycinderivate
CY2425B1 (en)	2004-11-12	2,4-Diaminopyrimidine derivatives.
ID26909A (id)	2001-02-15	Turunan-turunan 1,3,4-oksadiazolon
ZA982327B (en)	1999-09-20	Substituted 2-benz(O)ylpyridines.
DE69906149D1 (de)	2003-04-24	4,5-azolo-oxindole
TR199501562A2 (tr)	1996-07-21	Tiyenopiridon'lar.
ZA986160B (en)	2000-01-10	2,4,4-trisubstituted-1,3-dioxolone antifungals.
ID26368A (id)	2000-12-14	Turunan-turunan 2 deoksi higromisin
TR199700219A3 (tr)	1997-10-21	1,25-Dihidroksi-16, 22, 23-Trisdihidro-kolkalsiferol türevleri.
ZA984592B (en)	1999-11-29	Herbicidal 3,5-difluoropyridines.