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DK51092D0 - Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf - Google Patents

Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf

Info

Publication number
DK51092D0
DK51092D0 DK92510A DK51092A DK51092D0 DK 51092 D0 DK51092 D0 DK 51092D0 DK 92510 A DK92510 A DK 92510A DK 51092 A DK51092 A DK 51092A DK 51092 D0 DK51092 D0 DK 51092D0
Authority
DK
Denmark
Prior art keywords
synthones
monomeric
pen
procedures
preparing
Prior art date
Application number
DK92510A
Other languages
English (en)
Inventor
Ole Buchardt
Michael Egholm
Peter Eigil Nielsen
Rolf Henrik Berg
Original Assignee
Ole Buchardt
Michael Egholm
Peter Eigil Nielsen
Berg Rolf H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27220741&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK51092(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK98791A external-priority patent/DK98791D0/da
Priority claimed from DK98691A external-priority patent/DK98691D0/da
Application filed by Ole Buchardt, Michael Egholm, Peter Eigil Nielsen, Berg Rolf H filed Critical Ole Buchardt
Priority to DK92510A priority Critical patent/DK51092D0/da
Publication of DK51092D0 publication Critical patent/DK51092D0/da
Priority to BR9206049A priority patent/BR9206049A/pt
Priority to CA002109805A priority patent/CA2109805A1/en
Priority to DE69220946T priority patent/DE69220946T2/de
Priority to PCT/EP1992/001219 priority patent/WO1992020702A1/en
Priority to EP92923579A priority patent/EP0586618B1/en
Priority to AT92923579T priority patent/ATE155483T1/de
Priority to AT00203148T priority patent/ATE515569T1/de
Priority to EP92911165A priority patent/EP0586474B1/en
Priority to JP4510434A priority patent/JP2758988B2/ja
Priority to EP01203303A priority patent/EP1162206A3/en
Priority to CA002109320A priority patent/CA2109320C/en
Priority to PCT/EP1992/001220 priority patent/WO1992020703A1/en
Priority to ES92911165T priority patent/ES2164052T3/es
Priority to JP51013992A priority patent/JP3982828B2/ja
Priority to DE69232055T priority patent/DE69232055T2/de
Priority to EP00203148A priority patent/EP1074559B1/en
Priority to EP03077836A priority patent/EP1411063B1/en
Priority to ES92923579T priority patent/ES2107552T3/es
Priority to US08/108,591 priority patent/US6395474B1/en
Priority to DK92911165T priority patent/DK0586474T3/da
Priority to HU9303023A priority patent/HU221003B1/hu
Priority to AU18806/92A priority patent/AU666480B2/en
Priority to AT92911165T priority patent/ATE205504T1/de
Priority to US08/150,156 priority patent/US6357163B1/en
Priority to AU18843/92A priority patent/AU1884392A/en
Priority to DK92923579.4T priority patent/DK0586618T3/da
Priority to NO19934122A priority patent/NO312516B1/no
Priority to KR93703558A priority patent/KR0133131B1/ko
Priority to NO19934235A priority patent/NO313201B1/no
Priority to FI935208A priority patent/FI118424B/fi
Priority to US08/275,951 priority patent/US6451968B1/en
Priority to US08/319,411 priority patent/US7223833B1/en
Priority to US08/366,231 priority patent/US5977296A/en
Priority to US08/462,977 priority patent/US6713602B1/en
Priority to US08/468,719 priority patent/US6710163B1/en
Priority to US08/765,798 priority patent/US6441130B1/en
Priority to US08/595,387 priority patent/US5773571A/en
Priority to US08/686,114 priority patent/US6414112B1/en
Priority to US08/686,116 priority patent/US5714331A/en
Priority to US08/686,113 priority patent/US5766855A/en
Priority to US08/847,095 priority patent/US5786461A/en
Priority to US08/847,108 priority patent/US5736336A/en
Priority to GR970402663T priority patent/GR3025018T3/el
Priority to US09/209,149 priority patent/US6201103B1/en
Priority to US09/337,304 priority patent/US6613873B1/en
Priority to US09/955,410 priority patent/US20020146718A1/en
Priority to US09/983,210 priority patent/US20020160383A1/en
Priority to US10/154,890 priority patent/US7378485B2/en
Priority to US10/188,404 priority patent/US20030105286A1/en
Priority to JP2003015384A priority patent/JP2003235590A/ja
Priority to US10/657,600 priority patent/US20040059087A1/en
Priority to US10/691,012 priority patent/US20060160731A1/en
Priority to US10/755,118 priority patent/US20050009041A1/en
Priority to US11/029,005 priority patent/US20060046255A1/en
Priority to JP2007147536A priority patent/JP2007306926A/ja
Priority to JP2008060342A priority patent/JP2008253251A/ja
Priority to JP2008258890A priority patent/JP2009069158A/ja
Priority to US13/190,164 priority patent/US20120115136A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C07K14/003Peptide-nucleic acids (PNAs)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6832Enhancement of hybridisation reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK92510A 1991-05-24 1992-04-15 Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf DK51092D0 (da)

Priority Applications (59)

Application Number Priority Date Filing Date Title
DK92510A DK51092D0 (da) 1991-05-24 1992-04-15 Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
BR9206049A BR9206049A (pt) 1991-05-24 1992-05-22 Composto, processos para preparar o composto, para o reconhecimento específico por sequência de um polinucleotídio de filamento duplo, para modular a expressão de um gene em um organismo, para tratar as condições associadas com produção de proteínas indesejada em um organismo, para induzir a degradação de DNA ou RNA em células de um organismo e para exterminar células ou vírus e composição farmacêutica
CA002109805A CA2109805A1 (en) 1991-05-24 1992-05-22 The use of nucleic acid analogues in diagnostics and analytical procedures
DE69220946T DE69220946T2 (de) 1991-05-24 1992-05-22 Verwendung von nukleinsäureanaloga in diagnostischen und analytischen verfahren
PCT/EP1992/001219 WO1992020702A1 (en) 1991-05-24 1992-05-22 Peptide nucleic acids
EP92923579A EP0586618B1 (en) 1991-05-24 1992-05-22 The use of nucleic acid analogues in diagnostics and analytical procedures
AT92923579T ATE155483T1 (de) 1991-05-24 1992-05-22 Verwendung von nukleinsäureanaloga in diagnostischen und analytischen verfahren
AT00203148T ATE515569T1 (de) 1991-05-24 1992-05-22 Peptidnucleinsäuren
EP92911165A EP0586474B1 (en) 1991-05-24 1992-05-22 Peptide nucleic acids
JP4510434A JP2758988B2 (ja) 1991-05-24 1992-05-22 ペプチド核酸
EP01203303A EP1162206A3 (en) 1991-05-24 1992-05-22 Peptide nucleic acids
CA002109320A CA2109320C (en) 1991-05-24 1992-05-22 Peptide nucleic acids
PCT/EP1992/001220 WO1992020703A1 (en) 1991-05-24 1992-05-22 The use of nucleic acid analogues in diagnostics and analytical procedures
ES92911165T ES2164052T3 (es) 1991-05-24 1992-05-22 Acidos nucleicos de peptidos.
JP51013992A JP3982828B2 (ja) 1991-05-24 1992-05-22 診断薬および分析方法における核酸類縁体の使用方法
DE69232055T DE69232055T2 (de) 1991-05-24 1992-05-22 Peptidnukleinsäuren
EP00203148A EP1074559B1 (en) 1991-05-24 1992-05-22 Peptide nucleic acids
EP03077836A EP1411063B1 (en) 1991-05-24 1992-05-22 Peptide nucleic acids
ES92923579T ES2107552T3 (es) 1991-05-24 1992-05-22 Uso de analogos de acido nucleico en diagnosticos y procedimientos analiticos.
US08/108,591 US6395474B1 (en) 1991-05-24 1992-05-22 Peptide nucleic acids
DK92911165T DK0586474T3 (da) 1991-05-24 1992-05-22 Peptionukleinsyrer
HU9303023A HU221003B1 (hu) 1991-05-24 1992-05-22 Peptid-nukleinsavak
AU18806/92A AU666480B2 (en) 1991-05-24 1992-05-22 The use of nucleic acid analogues in diagnostics and analytical procedures
AT92911165T ATE205504T1 (de) 1991-05-24 1992-05-22 Peptidnukleinsäuren
US08/150,156 US6357163B1 (en) 1991-05-24 1992-05-22 Use of nucleic acid analogues in diagnostics and analytical procedures
AU18843/92A AU1884392A (en) 1991-05-24 1992-05-22 Peptide nucleic acids
DK92923579.4T DK0586618T3 (da) 1991-05-24 1992-05-22 Anvendelse af nuklainsyreanaloger i diagnostiske og analytiske fremgangsmåder
NO19934122A NO312516B1 (no) 1991-05-24 1993-11-15 Peptid-nukleinsyrer
KR93703558A KR0133131B1 (en) 1991-05-24 1993-11-20 Peptide nucleic acids
NO19934235A NO313201B1 (no) 1991-05-24 1993-11-23 Nukleinsyreanalog, anvendelse derav, in vitro-fremgangsmåte og kit
FI935208A FI118424B (fi) 1991-05-24 1993-11-23 Nukleiinihappoanalogit ja niiden käyttö diagnostisissa ja analyyttisissä toimenpiteissä
US08/275,951 US6451968B1 (en) 1991-05-24 1994-07-15 Peptide nucleic acids
US08/319,411 US7223833B1 (en) 1991-05-24 1994-10-06 Peptide nucleic acid conjugates
US08/366,231 US5977296A (en) 1991-05-24 1994-12-28 Chiral peptide nucleic acid monomers and oligomers
US08/462,977 US6713602B1 (en) 1991-05-24 1995-06-05 Synthetic procedures for peptide nucleic acids
US08/468,719 US6710163B1 (en) 1991-05-24 1995-06-06 Peptide nucleic acid synthons
US08/765,798 US6441130B1 (en) 1991-05-24 1995-07-13 Linked peptide nucleic acids
US08/595,387 US5773571A (en) 1991-05-24 1996-02-01 Peptide nucleic acids
US08/686,114 US6414112B1 (en) 1991-05-24 1996-07-24 Peptide nucleic acids having 2,6-diaminopurine nucleobases
US08/686,116 US5714331A (en) 1991-05-24 1996-07-24 Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US08/686,113 US5766855A (en) 1991-05-24 1996-07-24 Peptide nucleic acids having enhanced binding affinity and sequence specificity
US08/847,095 US5786461A (en) 1991-05-24 1997-05-01 Peptide nucleic acids having amino acid side chains
US08/847,108 US5736336A (en) 1991-05-24 1997-05-01 Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
GR970402663T GR3025018T3 (en) 1991-05-24 1997-10-14 The use of nucleic acid analogues in diagnostics and analytical procedures
US09/209,149 US6201103B1 (en) 1991-05-24 1998-12-10 Peptide nucleic acid incorporating a chiral backbone
US09/337,304 US6613873B1 (en) 1991-05-24 1999-06-21 Peptide nucleic acids having 2,6-diaminopurine nucleobases
US09/955,410 US20020146718A1 (en) 1991-05-24 2001-09-18 Peptide nucleic acids having 2,6-diaminopurine nucleobases
US09/983,210 US20020160383A1 (en) 1991-05-24 2001-10-23 Use of nucleic acid analogues in diagnostics and analytical procedures
US10/154,890 US7378485B2 (en) 1991-05-24 2002-05-23 Peptide nucleic acids with polyamide-containing backbones
US10/188,404 US20030105286A1 (en) 1991-05-24 2002-07-01 Linked peptide nucleic acids
JP2003015384A JP2003235590A (ja) 1991-05-24 2003-01-23 核酸類縁体並びに診断薬および分析方法におけるその使用方法
US10/657,600 US20040059087A1 (en) 1991-05-24 2003-09-08 Peptide nucleic acids
US10/691,012 US20060160731A1 (en) 1991-05-24 2003-10-22 Peptide nucleic acids
US10/755,118 US20050009041A1 (en) 1991-05-24 2004-01-09 Peptide nucleic acids and synthetic procedures therefor
US11/029,005 US20060046255A1 (en) 1991-05-24 2005-01-05 Use of nucleic acid analogues in diagnostics and analytical procedures
JP2007147536A JP2007306926A (ja) 1991-05-24 2007-06-01 核酸類縁体並びに診断薬および分析方法におけるその使用方法
JP2008060342A JP2008253251A (ja) 1991-05-24 2008-03-10 核酸類縁体並びに診断薬および分析方法におけるその使用方法
JP2008258890A JP2009069158A (ja) 1991-05-24 2008-10-03 核酸類縁体並びに診断薬および分析方法におけるその使用方法
US13/190,164 US20120115136A1 (en) 1991-05-24 2011-07-25 Pna diagnostic use

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK98791A DK98791D0 (da) 1991-05-24 1991-05-24 Fremgangsmaade til sekvensspecifik genkendelse af et dobbeltstrenget polynucleotid
DK98691A DK98691D0 (da) 1991-05-24 1991-05-24 Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
DK92510A DK51092D0 (da) 1991-05-24 1992-04-15 Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf

Publications (1)

Publication Number Publication Date
DK51092D0 true DK51092D0 (da) 1992-04-15

Family

ID=27220741

Family Applications (3)

Application Number Title Priority Date Filing Date
DK92510A DK51092D0 (da) 1991-05-24 1992-04-15 Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
DK92923579.4T DK0586618T3 (da) 1991-05-24 1992-05-22 Anvendelse af nuklainsyreanaloger i diagnostiske og analytiske fremgangsmåder
DK92911165T DK0586474T3 (da) 1991-05-24 1992-05-22 Peptionukleinsyrer

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK92923579.4T DK0586618T3 (da) 1991-05-24 1992-05-22 Anvendelse af nuklainsyreanaloger i diagnostiske og analytiske fremgangsmåder
DK92911165T DK0586474T3 (da) 1991-05-24 1992-05-22 Peptionukleinsyrer

Country Status (16)

Country Link
US (11) US6395474B1 (da)
EP (5) EP1162206A3 (da)
JP (6) JP3982828B2 (da)
KR (1) KR0133131B1 (da)
AT (3) ATE515569T1 (da)
AU (2) AU1884392A (da)
BR (1) BR9206049A (da)
CA (2) CA2109320C (da)
DE (2) DE69232055T2 (da)
DK (3) DK51092D0 (da)
ES (2) ES2164052T3 (da)
FI (1) FI118424B (da)
GR (1) GR3025018T3 (da)
HU (1) HU221003B1 (da)
NO (2) NO312516B1 (da)
WO (2) WO1992020703A1 (da)

Families Citing this family (374)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5852182A (en) * 1990-01-11 1998-12-22 Isis Pharmaceuticals Inc. Thiol-derivatized oligonucleosides
US5783682A (en) * 1990-07-27 1998-07-21 Isis Pharmaceuticals, Inc. Oligonucleotide mimics having nitrogen-containing linkages
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
US5766855A (en) * 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
US6228982B1 (en) * 1992-05-22 2001-05-08 Benget Norden Double-stranded peptide nucleic acids
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US7223833B1 (en) * 1991-05-24 2007-05-29 Isis Pharmaceuticals, Inc. Peptide nucleic acid conjugates
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
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DE69220946D1 (de) 1997-08-21
FI935208A7 (fi) 1993-11-23
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