DK421183D0 - Fremgangsmade til fremstilling af alfa-aryl-alfa-pyridylalkansyrer - Google Patents
Fremgangsmade til fremstilling af alfa-aryl-alfa-pyridylalkansyrerInfo
- Publication number
- DK421183D0 DK421183D0 DK4211/83A DK421183A DK421183D0 DK 421183 D0 DK421183 D0 DK 421183D0 DK 4211/83 A DK4211/83 A DK 4211/83A DK 421183 A DK421183 A DK 421183A DK 421183 D0 DK421183 D0 DK 421183D0
- Authority
- DK
- Denmark
- Prior art keywords
- sup
- lower alkyl
- alfa
- hydrogen
- aryl
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000007513 acids Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17293682 | 1982-09-30 | ||
| JP57172936A JPS5980664A (ja) | 1982-09-30 | 1982-09-30 | α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK421183D0 true DK421183D0 (da) | 1983-09-15 |
| DK421183A DK421183A (da) | 1984-03-31 |
| DK157854B DK157854B (da) | 1990-02-26 |
| DK157854C DK157854C (da) | 1990-07-23 |
Family
ID=15951089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK421183A DK157854C (da) | 1982-09-30 | 1983-09-15 | Analogifremgangsmaade til fremstilling af alfa-aryl-alfa-(2-pyridyl)-alkansyrederivater |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4564621A (da) |
| EP (1) | EP0105458B1 (da) |
| JP (1) | JPS5980664A (da) |
| KR (1) | KR900004694B1 (da) |
| AT (1) | ATE48130T1 (da) |
| CA (1) | CA1246573A (da) |
| DE (1) | DE3380876D1 (da) |
| DK (1) | DK157854C (da) |
| ES (1) | ES8603421A1 (da) |
| FI (1) | FI80878C (da) |
| GR (1) | GR78525B (da) |
| HU (1) | HU193046B (da) |
| NO (1) | NO162017C (da) |
| ZA (1) | ZA837069B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60112762A (ja) * | 1983-11-21 | 1985-06-19 | Fujisawa Pharmaceut Co Ltd | α−アリ−ル−α−ピリジル脂肪酸誘導体およびその製法 |
| US4810703A (en) * | 1984-10-19 | 1989-03-07 | A. H. Robins Company, Incorporated | 1-((aminoalkyl and aminoalkylamino)carbonyl and thiocarbonyl)-alpha, alpha-diarylpyrrolidine, piperidine and homopiperidineacetamides and acetonitriles |
| US4783537A (en) * | 1985-11-13 | 1988-11-08 | Pennwalt Corporation | α-(aminoalkyl)-arylacetic acid derivatives |
| US5202331A (en) * | 1990-04-18 | 1993-04-13 | Fujisawa Pharmaceutical Co., Ltd. | Therapeutic agent for dysuria comprising alpha-phenyl-alpha-pyridylalkanoic acid derivatives |
| JP5000841B2 (ja) * | 2001-01-24 | 2012-08-15 | カディラ ヘルスケア リミティド | クロピドグレルの製造方法 |
| AU2011245499B2 (en) | 2010-04-30 | 2014-09-25 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA501690A (en) * | 1954-04-20 | Schering Corporation | Pyridyl substituted alkanes | |
| NL70757C (da) * | 1947-10-13 | |||
| FR1235903A (fr) * | 1954-06-04 | 1960-11-10 | Pharmacia Ab | Procédé de préparation d'amides butyriles |
| US2991289A (en) * | 1958-02-05 | 1961-07-04 | Merck Ag E | Derivatives of 1-aminopropane |
| GB915804A (en) * | 1958-04-12 | 1963-01-16 | Degussa | Process for the production of basically substituted carboxylic acid amides |
| FR2485M (fr) * | 1961-05-17 | 1964-04-27 | Searle & Co | Nouveaux régulateurs cardiaques. |
| US3225054A (en) * | 1962-07-03 | 1965-12-21 | Searle & Co | 4-dipropylamino-2-aryl-2-pyridylalkanamides |
| JPS5248862B2 (da) * | 1971-08-16 | 1977-12-13 |
-
1982
- 1982-09-30 JP JP57172936A patent/JPS5980664A/ja active Granted
-
1983
- 1983-09-08 GR GR72407A patent/GR78525B/el unknown
- 1983-09-15 DK DK421183A patent/DK157854C/da not_active IP Right Cessation
- 1983-09-19 KR KR1019830004386A patent/KR900004694B1/ko not_active Expired
- 1983-09-21 FI FI833369A patent/FI80878C/fi not_active IP Right Cessation
- 1983-09-22 ZA ZA837069A patent/ZA837069B/xx unknown
- 1983-09-23 US US06/535,298 patent/US4564621A/en not_active Expired - Lifetime
- 1983-09-28 AT AT83109659T patent/ATE48130T1/de not_active IP Right Cessation
- 1983-09-28 EP EP83109659A patent/EP0105458B1/en not_active Expired
- 1983-09-28 ES ES526026A patent/ES8603421A1/es not_active Expired
- 1983-09-28 DE DE8383109659T patent/DE3380876D1/de not_active Expired
- 1983-09-29 HU HU833400A patent/HU193046B/hu not_active IP Right Cessation
- 1983-09-29 CA CA000437939A patent/CA1246573A/en not_active Expired
- 1983-09-29 NO NO833529A patent/NO162017C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK157854C (da) | 1990-07-23 |
| NO833529L (no) | 1984-04-02 |
| ES526026A0 (es) | 1985-12-16 |
| JPS5980664A (ja) | 1984-05-10 |
| US4564621A (en) | 1986-01-14 |
| FI80878C (fi) | 1990-08-10 |
| FI833369A0 (fi) | 1983-09-21 |
| HU193046B (en) | 1987-08-28 |
| GR78525B (da) | 1984-09-27 |
| DK157854B (da) | 1990-02-26 |
| EP0105458A2 (en) | 1984-04-18 |
| KR900004694B1 (ko) | 1990-07-02 |
| JPS635025B2 (da) | 1988-02-01 |
| EP0105458A3 (en) | 1985-11-27 |
| ATE48130T1 (de) | 1989-12-15 |
| FI80878B (fi) | 1990-04-30 |
| DE3380876D1 (en) | 1989-12-28 |
| EP0105458B1 (en) | 1989-11-23 |
| NO162017B (no) | 1989-07-17 |
| DK421183A (da) | 1984-03-31 |
| NO162017C (no) | 1989-10-25 |
| ZA837069B (en) | 1984-05-30 |
| KR840006238A (ko) | 1984-11-22 |
| FI833369A7 (fi) | 1984-03-31 |
| CA1246573A (en) | 1988-12-13 |
| ES8603421A1 (es) | 1985-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |