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DK406483D0 - METHOD OF PREPARING HEPATITIS B VIRUS VACCINE - Google Patents

METHOD OF PREPARING HEPATITIS B VIRUS VACCINE

Info

Publication number
DK406483D0
DK406483D0 DK4064/83A DK406483A DK406483D0 DK 406483 D0 DK406483 D0 DK 406483D0 DK 4064/83 A DK4064/83 A DK 4064/83A DK 406483 A DK406483 A DK 406483A DK 406483 D0 DK406483 D0 DK 406483D0
Authority
DK
Denmark
Prior art keywords
virus vaccine
yeast
preparing hepatitis
hbsag
gene
Prior art date
Application number
DK4064/83A
Other languages
Danish (da)
Other versions
DK406483A (en
Inventor
Theresa Cabezon
Marjolene Crabeel
Michel De Wilde
Nigel Harford
Original Assignee
Smith Kline Rit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline Rit filed Critical Smith Kline Rit
Publication of DK406483D0 publication Critical patent/DK406483D0/en
Publication of DK406483A publication Critical patent/DK406483A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

A DNA fragment capable of coding for HBsAg and DNA derivatives of Dane particles is fused to the region for controlling the arg3 gene of yeast and cloned in a yeast vector. The recombinant vector is employed for transforming the competent yeast cells in which the HBsAg gene is expressed.
DK406483A 1982-09-08 1983-09-07 METHOD OF PREPARING HEPATITIS B VIRUS VACCINE DK406483A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41578982A 1982-09-08 1982-09-08

Publications (2)

Publication Number Publication Date
DK406483D0 true DK406483D0 (en) 1983-09-07
DK406483A DK406483A (en) 1984-03-09

Family

ID=23647197

Family Applications (1)

Application Number Title Priority Date Filing Date
DK406483A DK406483A (en) 1982-09-08 1983-09-07 METHOD OF PREPARING HEPATITIS B VIRUS VACCINE

Country Status (22)

Country Link
EP (1) EP0106828B1 (en)
JP (5) JPS5971694A (en)
KR (1) KR840006014A (en)
AT (1) ATE91718T1 (en)
AU (4) AU584580B2 (en)
CA (1) CA1222707A (en)
CY (1) CY1932A (en)
DE (1) DE3382704T2 (en)
DK (1) DK406483A (en)
ES (4) ES525439A0 (en)
FI (1) FI833205L (en)
GR (1) GR78982B (en)
HK (1) HK1004570A1 (en)
HU (1) HU196625B (en)
IE (1) IE60387B1 (en)
IL (1) IL69202A (en)
MA (1) MA19895A1 (en)
MY (1) MY102920A (en)
NO (1) NO833198L (en)
NZ (1) NZ204952A (en)
PT (1) PT77265B (en)
ZA (1) ZA836658B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936699A (en) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst Shuttle vector
JPS5931799A (en) * 1982-08-16 1984-02-20 Science & Tech Agency Recombinant plasmid and preparation of transformed yeast and hepatitis virus b surface antigen using the same
WO1986007384A1 (en) * 1985-06-03 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing hapatitis b virus surface antigen p31
WO1986001534A1 (en) * 1984-09-04 1986-03-13 Takeda Chemical Industries, Ltd. Recombinant dna and its use
WO1986003411A1 (en) * 1984-12-12 1986-06-19 Takeda Chemical Industries, Ltd. Process for preparing novel protein
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
DE3677851D1 (en) * 1985-08-05 1991-04-11 Merck & Co Inc METHOD FOR INCREASING THE PRODUCTION OF RECOMBINANT PROTEIN IN YEARS OF THE GENERATION SACCHAROMYCES.
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen
AP56A (en) * 1987-01-30 1989-09-26 Smithkline Biologicals S A Hepatitis B virus surface antigens and hybrid antigehs containing them.
DE3883596T2 (en) * 1987-03-09 1994-02-17 Merck & Co Inc Purification of recombined hepatitis B surface antigen.
NZ229260A (en) * 1988-06-03 1994-02-25 Merck & Co Inc Hepatitis b virus, expression cassette for pre-s domain, host cells and
US4962656A (en) * 1989-06-30 1990-10-16 The United States Of America As Represented By The United States Department Of Energy Control and monitoring method and system for electromagnetic forming process
LT3988B (en) 1992-02-17 1996-06-25 Fermentas Biotech Inst Recombinant plasmides pfs19, pfps2-48 and pjlfds1 codingsynthesis of human hepatite b of surfice virus antigenes, methods fof producing thereof
TW340132B (en) * 1994-10-20 1998-09-11 Ibm Structure for use as an electrical interconnection means and process for preparing the same
JP4028850B2 (en) * 2004-02-04 2007-12-26 株式会社名機製作所 Mold for molding disk substrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU88258I2 (en) * 1978-12-22 1994-02-03
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
GR76274B (en) * 1981-08-04 1984-08-04 Univ California
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides

Also Published As

Publication number Publication date
KR840006014A (en) 1984-11-21
AU3131889A (en) 1989-07-20
ES532730A0 (en) 1985-10-16
DE3382704D1 (en) 1993-08-26
ES8506350A1 (en) 1985-07-01
ES8600939A1 (en) 1985-10-16
EP0106828A3 (en) 1985-11-21
CY1932A (en) 1983-09-06
IE832099L (en) 1984-03-08
JP2522825B2 (en) 1996-08-07
JPH08317796A (en) 1996-12-03
JP2702899B2 (en) 1998-01-26
NZ204952A (en) 1986-05-09
PT77265A (en) 1983-09-01
JPH02116A (en) 1990-01-05
PT77265B (en) 1986-02-04
FI833205A0 (en) 1983-09-07
ES8600938A1 (en) 1985-10-16
AU1675083A (en) 1984-03-15
CA1222707A (en) 1987-06-09
JPH02464A (en) 1990-01-05
ES532732A0 (en) 1985-10-16
ES8602120A1 (en) 1985-11-01
GR78982B (en) 1984-10-02
EP0106828A2 (en) 1984-04-25
FI833205A7 (en) 1984-03-09
FI833205L (en) 1984-03-09
AU1569288A (en) 1988-07-28
IL69202A (en) 1991-08-16
MA19895A1 (en) 1984-04-01
AU584580B2 (en) 1989-06-01
ES532731A0 (en) 1985-11-01
HU196625B (en) 1988-12-28
ATE91718T1 (en) 1993-08-15
MY102920A (en) 1993-03-31
ZA836658B (en) 1984-06-27
EP0106828B1 (en) 1993-07-21
IE60387B1 (en) 1994-07-13
ES525439A0 (en) 1985-07-01
HK1004570A1 (en) 1998-11-27
DE3382704T2 (en) 1994-02-10
DK406483A (en) 1984-03-09
JPS5971694A (en) 1984-04-23
NO833198L (en) 1984-03-09
AU9001491A (en) 1992-02-27
JPH02231084A (en) 1990-09-13

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AHB Application shelved due to non-payment