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DK4058148T3 - Doseringsregime for anti-bcma-midler - Google Patents

Doseringsregime for anti-bcma-midler Download PDF

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Publication number
DK4058148T3
DK4058148T3 DK20729951.2T DK20729951T DK4058148T3 DK 4058148 T3 DK4058148 T3 DK 4058148T3 DK 20729951 T DK20729951 T DK 20729951T DK 4058148 T3 DK4058148 T3 DK 4058148T3
Authority
DK
Denmark
Prior art keywords
bcma
agents
dosage regime
regime
dosage
Prior art date
Application number
DK20729951.2T
Other languages
English (en)
Other versions
DK4058148T5 (da
Inventor
Julia Stieglmaier
Birgit Huber
Vijay Upreti
Alexander Minella
Original Assignee
Amgen Res Munich Gmbh
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=68581157&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK4058148(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Res Munich Gmbh, Amgen Inc filed Critical Amgen Res Munich Gmbh
Application granted granted Critical
Publication of DK4058148T3 publication Critical patent/DK4058148T3/da
Publication of DK4058148T5 publication Critical patent/DK4058148T5/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK20729951.2T 2019-11-11 2020-05-08 Doseringsregime for anti-bcma-midler DK4058148T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19208417.6A EP3819007B1 (en) 2019-11-11 2019-11-11 Dosing regimen for anti-bcma agents
PCT/EP2020/062876 WO2021094000A1 (en) 2019-11-11 2020-05-08 Dosing regimen for anti-bcma agents

Publications (2)

Publication Number Publication Date
DK4058148T3 true DK4058148T3 (da) 2024-05-06
DK4058148T5 DK4058148T5 (da) 2024-07-22

Family

ID=68581157

Family Applications (2)

Application Number Title Priority Date Filing Date
DK19208417.6T DK3819007T3 (da) 2019-11-11 2019-11-11 Doseringsplan for anti-bcma-midler
DK20729951.2T DK4058148T5 (da) 2019-11-11 2020-05-08 Doseringsregime for anti-bcma-midler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK19208417.6T DK3819007T3 (da) 2019-11-11 2019-11-11 Doseringsplan for anti-bcma-midler

Country Status (20)

Country Link
US (1) US20210139584A1 (da)
EP (3) EP3819007B1 (da)
JP (2) JP2022554362A (da)
AU (1) AU2020381671A1 (da)
CA (1) CA3155069A1 (da)
DK (2) DK3819007T3 (da)
ES (2) ES2987783T3 (da)
FI (2) FI3819007T3 (da)
HR (2) HRP20241281T1 (da)
HU (2) HUE068401T2 (da)
LT (2) LT3819007T (da)
MA (1) MA47888B1 (da)
MX (1) MX2022005628A (da)
PL (2) PL3819007T3 (da)
PT (2) PT3819007T (da)
RS (2) RS65943B1 (da)
SI (2) SI3819007T1 (da)
SM (2) SMT202400373T1 (da)
TW (1) TW202118784A (da)
WO (1) WO2021094000A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112019012354A2 (pt) 2016-12-21 2019-11-26 Teneobio Inc anticorpos apenas de cadeia pesada anti-bcma
WO2022103781A1 (en) * 2020-11-10 2022-05-19 Amgen Inc. Methods for administering a bcma x cd3 binding molecule
WO2023098846A1 (zh) * 2021-12-03 2023-06-08 江苏先声药业有限公司 抗bcma纳米抗体及其应用

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Also Published As

Publication number Publication date
JP2025170264A (ja) 2025-11-18
DK4058148T5 (da) 2024-07-22
EP4424709A2 (en) 2024-09-04
HRP20240553T1 (hr) 2024-07-05
PT3819007T (pt) 2024-09-20
FI4058148T3 (fi) 2024-05-06
ES2987070T3 (es) 2024-11-13
FI3819007T3 (fi) 2024-09-25
EP4424709A3 (en) 2024-12-11
EP4058148A1 (en) 2022-09-21
EP4058148B1 (en) 2024-03-13
MA47888B1 (fr) 2024-10-31
EP3819007A1 (en) 2021-05-12
HUE068401T2 (hu) 2024-12-28
PL3819007T3 (pl) 2024-11-18
AU2020381671A1 (en) 2022-03-31
DK3819007T3 (da) 2024-09-30
WO2021094000A1 (en) 2021-05-20
PT4058148T (pt) 2024-05-03
SI4058148T1 (sl) 2024-06-28
RS65943B1 (sr) 2024-10-31
SMT202400165T1 (it) 2024-05-14
TW202118784A (zh) 2021-05-16
JP2022554362A (ja) 2022-12-28
MX2022005628A (es) 2022-06-14
US20210139584A1 (en) 2021-05-13
RS65581B1 (sr) 2024-06-28
HUE066166T2 (hu) 2024-07-28
SI3819007T1 (sl) 2024-10-30
LT3819007T (lt) 2024-10-10
PL4058148T3 (pl) 2024-09-16
SMT202400373T1 (it) 2024-11-15
CA3155069A1 (en) 2021-05-20
HRP20241281T1 (hr) 2024-12-06
EP3819007B1 (en) 2024-07-10
ES2987783T3 (es) 2024-11-18
LT4058148T (lt) 2024-05-27

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