DK395689D0 - Pharmaceutisk tilberedning til behandling af diabetes mellitus - Google Patents

Pharmaceutisk tilberedning til behandling af diabetes mellitus

Info

Publication number: DK395689D0
Authority: DK; Denmark
Prior art keywords: treatment; diabetes mellitus; arg; insulin; pharmaceutical preparation
Prior art date: 1988-08-13

Application number

DK395689A

Other languages

English (en)

Other versions

DK395689A (da

Inventor

Michael Doerschug

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-13

Filing date

1989-08-11

Publication date

1989-08-11

1989-08-11 Application filed by Hoechst Ag filed Critical Hoechst Ag

1989-08-11 Publication of DK395689D0 publication Critical patent/DK395689D0/da

1990-02-14 Publication of DK395689A publication Critical patent/DK395689A/da

Links

206010012601 diabetes mellitus Diseases 0.000 title abstract 3
239000000825 pharmaceutical preparation Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 abstract 3
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical class N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
239000004026 insulin derivative Substances 0.000 abstract 2
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 abstract 1
230000002349 favourable effect Effects 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000011701 zinc Substances 0.000 abstract 1
229910052725 zinc Inorganic materials 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Obesity (AREA)
Hematology (AREA)
Organic Chemistry (AREA)
Emergency Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK395689A 1988-08-13 1989-08-11 Pharmaceutisk tilberedning til behandling af diabetes mellitus DK395689A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3827533A DE3827533A1 (de)	1988-08-13	1988-08-13	Pharmazeutische zubereitung zur behandlung des diabetes mellitus

Publications (2)

Publication Number	Publication Date
DK395689D0 true DK395689D0 (da)	1989-08-11
DK395689A DK395689A (da)	1990-02-14

Family

ID=6360797

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK395689A DK395689A (da)	1988-08-13	1989-08-11	Pharmaceutisk tilberedning til behandling af diabetes mellitus

Country Status (18)

Country	Link
US (1)	US5177058A (da)
EP (1)	EP0357978B1 (da)
JP (1)	JPH02101022A (da)
KR (1)	KR900002801A (da)
AT (1)	ATE75945T1 (da)
AU (1)	AU621648B2 (da)
CA (1)	CA1332354C (da)
DE (2)	DE3827533A1 (da)
DK (1)	DK395689A (da)
ES (1)	ES2039773T3 (da)
FI (1)	FI95202C (da)
GR (1)	GR3005326T3 (da)
HU (1)	HU203670B (da)
IE (1)	IE61266B1 (da)
NO (1)	NO178914C (da)
NZ (1)	NZ230280A (da)
PT (1)	PT91420B (da)
ZA (1)	ZA896149B (da)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6875589B1 (en) *	1988-06-23	2005-04-05	Hoechst Aktiengesellschaft	Mini-proinsulin, its preparation and use
DE4024434A1 (de) *	1990-08-01	1992-02-13	Fresenius Ag	Vorrichtung zur ultrafiltrationskontrolle bzw. ultrafiltrationsregelung bei blutreinigungsverfahren
HU225496B1 (en) *	1993-04-07	2007-01-29	Scios Inc	Pharmaceutical compositions of prolonged delivery, containing peptides
US5534488A (en) *	1993-08-13	1996-07-09	Eli Lilly And Company	Insulin formulation
YU18596A (sh) *	1995-03-31	1998-07-10	Eli Lilly And Company	Analogne formulacije monomernog insulina
ATE264871T1 (de) *	1996-07-26	2004-05-15	Aventis Pharma Gmbh	Insulinderivate mit erhöhter zinkbindung
EP1044016B1 (en) *	1998-01-09	2005-03-16	Novo Nordisk A/S	Stabilised insulin compositions
DE19825447A1 (de)	1998-06-06	1999-12-09	Hoechst Marion Roussel De Gmbh	Neue Insulinanaloga mit erhöhter Zinkbildung
DE10114178A1 (de) *	2001-03-23	2002-10-10	Aventis Pharma Gmbh	Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
SK2432004A3 (sk) *	2001-12-20	2005-04-01	Eli Lilly And Company	Inzulínová zlúčenina s protrahovaným účinkom
DE10227232A1 (de) *	2002-06-18	2004-01-15	Aventis Pharma Deutschland Gmbh	Saure Insulinzubereitungen mit verbesserter Stabilität
CA2518776A1 (en) *	2003-04-29	2004-11-11	Eli Lilly And Company	Insulin analogs having protracted time action
EP2107069B1 (en) *	2003-08-05	2013-01-16	Novo Nordisk A/S	Novel insulin derivatives
US7872095B2 (en)	2004-07-19	2011-01-18	Biocon Limited	Insulin-oligomer conjugates, formulations and uses thereof
PL1969004T3 (pl) *	2005-12-28	2012-01-31	Novo Nordisk As	Kompozycje zawierające acylowaną insulinę i cynk oraz sposób wytwarzania tych kompozycji
WO2008152106A1 (en) *	2007-06-13	2008-12-18	Novo Nordisk A/S	Pharmaceutical formulation comprising an insulin derivative
CN101939023B (zh) *	2007-10-16	2016-08-03	百康有限公司	可经口给药的固体药物组合物及其方法
PT2349324T (pt)	2008-10-17	2017-12-06	Sanofi Aventis Deutschland	Combinação de uma insulina e de um agonista do glp-1
KR20110085985A (ko) *	2008-10-30	2011-07-27	노보 노르디스크 에이/에스	하루 한번 주사 빈도보다 적은 인슐린 주사를 사용한 진성 당뇨병의 치료
SG10201500871TA (en)	2009-11-13	2015-04-29	Sanofi Aventis Deutschland	Pharmaceutical composition comprising a glp-1 agonist and methionine
WO2011058083A1 (de)	2009-11-13	2011-05-19	Sanofi-Aventis Deutschland Gmbh	Pharmazeutische zusammensetzung umfassend einen glp-1-agonisten, ein insulin und methionin
RS55378B1 (sr)	2010-08-30	2017-03-31	Sanofi Aventis Deutschland	Upotreba ave0010 za proizvodnju leka za tretman diabetes mellitus tipa 2
DK2632478T3 (da)	2010-10-27	2019-10-07	Novo Nordisk As	Behandling af diabetes melitus under anvendelse af insulinindsprøjtninger indgivet med varierende indsprøjtningsintervaller
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
HRP20151068T1 (hr)	2011-08-29	2016-01-01	Sanofi-Aventis Deutschland Gmbh	Farmaceutska kombinacija za upotrebu za glikemijsku kontrolu kod pacijenata s dijabetesom tipa 2
AR087744A1 (es)	2011-09-01	2014-04-16	Sanofi Aventis Deutschland	Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
EP2991672A1 (en)	2013-04-30	2016-03-09	Novo Nordisk A/S	Novel administration regime
TWI758239B (zh)	2014-12-12	2022-03-21	德商賽諾菲阿凡提斯德意志有限公司	甘精胰島素/利司那肽固定比率配製劑
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療
US10335464B1 (en)	2018-06-26	2019-07-02	Novo Nordisk A/S	Device for titrating basal insulin
US12343383B2 (en)	2019-07-12	2025-07-01	Novo Nordisk A/S	High concentration insulin formulation

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2143591A (en) *	1936-09-26	1939-01-10	Univ Alberta	Therapeutic preparation and process of making and using it
US2354211A (en) *	1940-07-02	1944-07-25	Burroughs Wellcome Co	Insulin preparation
DOP1982004086A (es) *	1981-08-27	1988-03-22	Lilly Co Eli	Formula farmaceutica que comprende insulina humana y proinsulina humana
DE3326473A1 (de) *	1983-07-22	1985-01-31	Hoechst Ag, 6230 Frankfurt	Pharmazeutisches mittel zur behandlung des diabetes mellitus
DE3326472A1 (de) *	1983-07-22	1985-02-14	Hoechst Ag, 6230 Frankfurt	Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3333640A1 (de) *	1983-09-17	1985-04-25	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DE3334407A1 (de) *	1983-09-23	1985-04-04	Hoechst Ag, 6230 Frankfurt	In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DK347086D0 (da) *	1986-07-21	1986-07-21	Novo Industri As	Novel peptides
DK113585D0 (da) *	1985-03-12	1985-03-12	Novo Industri As	Nye peptider

1988
- 1988-08-13 DE DE3827533A patent/DE3827533A1/de not_active Withdrawn
1989
- 1989-08-08 DE DE8989114617T patent/DE58901401D1/de not_active Expired - Lifetime
- 1989-08-08 ES ES89114617T patent/ES2039773T3/es not_active Expired - Lifetime
- 1989-08-08 AT AT89114617T patent/ATE75945T1/de not_active IP Right Cessation
- 1989-08-08 EP EP89114617A patent/EP0357978B1/de not_active Expired - Lifetime
- 1989-08-10 FI FI893783A patent/FI95202C/fi not_active IP Right Cessation
- 1989-08-10 PT PT91420A patent/PT91420B/pt not_active IP Right Cessation
- 1989-08-11 HU HU894148A patent/HU203670B/hu unknown
- 1989-08-11 NO NO893239A patent/NO178914C/no unknown
- 1989-08-11 JP JP1207057A patent/JPH02101022A/ja active Pending
- 1989-08-11 US US07/392,559 patent/US5177058A/en not_active Expired - Lifetime
- 1989-08-11 IE IE259489A patent/IE61266B1/en not_active IP Right Cessation
- 1989-08-11 ZA ZA896149A patent/ZA896149B/xx unknown
- 1989-08-11 AU AU39514/89A patent/AU621648B2/en not_active Expired
- 1989-08-11 DK DK395689A patent/DK395689A/da not_active Application Discontinuation
- 1989-08-11 NZ NZ230280A patent/NZ230280A/xx unknown
- 1989-08-11 CA CA000608115A patent/CA1332354C/en not_active Expired - Lifetime
- 1989-08-11 KR KR1019890011430A patent/KR900002801A/ko not_active Withdrawn
1992
- 1992-07-31 GR GR920401367T patent/GR3005326T3/el unknown

Also Published As

Publication number	Publication date
FI893783L (fi)	1990-02-14
PT91420A (pt)	1990-03-08
ZA896149B (en)	1990-04-25
DE3827533A1 (de)	1990-02-15
NO178914B (no)	1996-03-25
ES2039773T3 (es)	1996-07-16
ATE75945T1 (de)	1992-05-15
GR3005326T3 (da)	1993-05-24
US5177058A (en)	1993-01-05
DE58901401D1 (de)	1992-06-17
EP0357978B1 (de)	1992-05-13
FI95202B (fi)	1995-09-29
EP0357978A1 (de)	1990-03-14
FI893783A0 (fi)	1989-08-10
DK395689A (da)	1990-02-14
IE61266B1 (en)	1994-10-19
NO178914C (no)	1996-07-03
AU621648B2 (en)	1992-03-19
FI95202C (fi)	1996-01-10
KR900002801A (ko)	1990-03-23
AU3951489A (en)	1990-02-15
PT91420B (pt)	1995-05-04
NO893239D0 (no)	1989-08-11
HU203670B (en)	1991-09-30
NZ230280A (en)	1991-09-25
JPH02101022A (ja)	1990-04-12
IE892594L (en)	1990-02-13
CA1332354C (en)	1994-10-11
HUT50443A (en)	1990-02-28
NO893239L (no)	1990-02-14

Publication	Publication Date	Title
DK395689A (da)	1990-02-14	Pharmaceutisk tilberedning til behandling af diabetes mellitus
CA2093806A1 (en)	1992-04-11	Method of treating or preventing type 1 diabetes by oral administration of insulin
DK642587A (da)	1987-12-08	Insulinpraeparat
IL85523A (en)	1992-11-15	Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it
ATE33503T1 (de)	1988-04-15	Pharmazeutische und tiermedizinische praeparate von interleukin-2, in dem cystein-125 ausgetauscht worden ist (muteine), sowie deren herstellung.
BR9709845B1 (pt)	2008-11-18	preparaÇço aquosa de insulina, formulaÇço farmacÊutica parenteral, e, processso para aumentar a estabilidade quÍmica de uma preparaÇço de insulina.
BR9401199A (pt)	1994-10-18	Preparados de medicamentos, processo para a preparação de um preparado de medicamento, processo para a preparação de uma formulação de medicamento.
DE3875108D1 (de)	1992-11-05	Physiologisch aktives polypeptid und pharmazeutische komposition.
ATE97572T1 (de)	1993-12-15	Azelastin enthaltende arzneimittel mit kontrollierter wirkstoffabgabe.
AU8687391A (en)	1992-05-07	Lithium treatment
PH27446A (en)	1993-07-02	Compound with gastric acid inhibitory effect
EP0230264A3 (en)	1988-12-14	Pharmaceutical composition for nasal application, process for its preparation and its use
GR3002765T3 (en)	1993-01-25	New pharmaceutical compositions for parenteral use containing a calcitonin as the active ingredient
NO810480L (no)	1981-08-14	Anologifremgangsmaate for fremstilling av terapeutisk aktive 1,3,4-oksadiazolylfenol-derivater
ES512748A0 (es)	1983-03-01	"procedimiento para la preparacion de comprimidos a base del antibiotico fosfomicina".
DK0560207T3 (da)	2000-02-07	Præparat til oral anvendelse baseret på ibuprofen
DK493887A (da)	1987-09-21	Buccal formulering

Legal Events

Date	Code	Title	Description
1996-07-29	ATS	Application withdrawn