DK385586A - Fremgangsmaade til fremstilling af en stabil modifikation af torasemid saavel som farmaceutisk praeparat, der indeholder torasemid - Google Patents

Fremgangsmaade til fremstilling af en stabil modifikation af torasemid saavel som farmaceutisk praeparat, der indeholder torasemid Download PDF

Info

Publication number: DK385586A
Authority: DK; Denmark
Prior art keywords: torasemid; preparing; software; procedure; pharmaceutical preparation
Prior art date: 1985-08-17

Application number

DK385586A

Other languages

English (en)

Other versions

DK162518C (da

DK162518B (da

DK385586D0 (da

Inventor

Fritz Topfmeier

Gustav Lettenbauer

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-17

Filing date

1986-08-13

Publication date

1987-02-18

1986-08-13 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1986-08-13 Publication of DK385586D0 publication Critical patent/DK385586D0/da

1987-02-18 Publication of DK385586A publication Critical patent/DK385586A/da

1991-11-11 Publication of DK162518B publication Critical patent/DK162518B/da

1992-03-30 Application granted granted Critical

1992-03-30 Publication of DK162518C publication Critical patent/DK162518C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Compounds Of Unknown Constitution (AREA)

DK385586A 1985-08-17 1986-08-13 Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne DK162518C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19853529529 DE3529529A1 (de)	1985-08-17	1985-08-17	Verfahren zur herstellung einer stabilen modifikation von torasemid
DE3529529		1985-08-17

Publications (4)

Publication Number	Publication Date
DK385586D0 DK385586D0 (da)	1986-08-13
DK385586A true DK385586A (da)	1987-02-18
DK162518B DK162518B (da)	1991-11-11
DK162518C DK162518C (da)	1992-03-30

Family

ID=6278766

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK385586A DK162518C (da)	1985-08-17	1986-08-13	Fremgangsmaade til fremstilling af en stabil modifikation af torasemid, samt et farmaceutisk praeparat indeholdende denne

Country Status (25)

Country	Link
US (4)	US4743693A (da)
EP (1)	EP0212537B1 (da)
JP (2)	JPS6245576A (da)
KR (1)	KR930009818B1 (da)
AU (1)	AU573454B2 (da)
CA (1)	CA1307277C (da)
CS (2)	CS259891B2 (da)
DD (1)	DD259858A5 (da)
DE (2)	DE3529529A1 (da)
DK (1)	DK162518C (da)
ES (1)	ES2001522A6 (da)
FI (1)	FI82189C (da)
GR (1)	GR862139B (da)
HK (1)	HK59994A (da)
HU (1)	HU195778B (da)
IE (1)	IE59237B1 (da)
IL (1)	IL79672A (da)
LT (1)	LT3596B (da)
NO (1)	NO170079C (da)
NZ (1)	NZ217172A (da)
PL (1)	PL146086B1 (da)
PT (1)	PT83186B (da)
SU (1)	SU1480766A3 (da)
UA (1)	UA7080A1 (da)
ZA (1)	ZA866151B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3623620A1 (de) *	1986-07-12	1988-01-21	Boehringer Mannheim Gmbh	Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung
US5166162A (en) *	1990-03-02	1992-11-24	Adir Et Compagnie	Pyridylsulfonylurea and pyridylsulfonylthiourea compounds
JP3586471B2 (ja) *	1991-06-25	2004-11-10	三菱ウェルファーマ株式会社	トラセミド含有医薬組成物
TW257757B (da) *	1993-03-03	1995-09-21	Boehringer Mannheim Gmbh
HRP980532B1 (en) *	1998-10-02	2005-06-30	Pliva	Novel crystalline torasemide modification
US5914336A (en)	1998-06-02	1999-06-22	Boehringer Mannheim Gmbh	Method of controlling the serum solubility of orally administered torasemide and composition relating thereto
US6166045A (en)	1998-06-02	2000-12-26	Roche Diagnostics Gmbh	Torasemide of modification III
US20030026835A1 (en) *	1999-02-15	2003-02-06	Sumitomo Pharmaceuticals Company Limited	Tablets disintegrating rapidly in the oral cavity
SI20816A (sl) *	1999-08-11	2002-08-31	Teva Pharmaceutical Industries Ltd.	Polimorfi torsemid-a
MXPA03007908A (es) *	2000-02-17	2004-12-06	Teva Pharma	Una formulacion farmaceutica estable que comprende una modificacion de torsemida ii.
US6635765B2 (en)	2000-03-20	2003-10-21	Teva Pharmaceutical Industries, Ltd.	Processes for preparing torsemide intermediate
HRP20000162B1 (en) *	2000-03-20	2004-06-30	Pliva D D	Amorphous torasemide modification
HRP20000765A2 (en) *	2000-11-10	2002-06-30	Pliva D D	Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
US20030022921A1 (en) *	2001-02-21	2003-01-30	Minutza Leibovici	Stable pharmaceutical formulation comprising torsemide modification II
IN192178B (da) *	2001-08-03	2004-03-06	Ranbaxy Lab
CA2477088A1 (en)	2002-02-22	2003-10-02	New River Pharmaceuticals Inc.	Active agent delivery systems and methods for protecting and administering active agents
ITMI20020639A1 (it) *	2002-03-27	2003-09-29	Cosma S P A	Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea
HRP20020603B1 (en) *	2002-07-19	2008-11-30	Pliva D.D.	New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide
ATE358675T1 (de) *	2002-11-18	2007-04-15	Teva Pharma	Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol
US7678816B2 (en) *	2003-02-05	2010-03-16	Teva Pharmaceutical Industries Ltd.	Method of stabilizing lansoprazole
ES2244324B1 (es) *	2004-03-25	2006-11-16	Ferrer Internacional, S.A.	Composiciones diureticas de liberacion prolongada.
AT500576B1 (de) *	2004-07-28	2006-11-15	Sanochemia Pharmazeutika Ag	Verfahren zur reindarstellung von kristallformen von torsemid
US10178893B1 (en) *	2013-06-14	2019-01-15	Scott Bradley Baker	Shoe
FR3018688A1 (fr) *	2014-03-19	2015-09-25	Virbac	Utilisation de torasemide a faible dose dans une composition veterinaire
US12048677B2 (en)	2014-12-12	2024-07-30	Ceva Sante Animale	Compositions and uses thereof for the treatment of heart failure in domestic animals
EP3031471A1 (en) *	2014-12-12	2016-06-15	Ceva Sante Animale	Veterinary composition for the treatment of pulmonary edema associated with heart failure in domestic animals
SI3173075T1 (sl) *	2015-11-27	2019-02-28	Accupharma Spolka Z Ograniczona Odpowiedzialnoscia	Farmacevtski kombinacijski pripravek inhibitorja ACE in diuretika zanke
CN115417810B (zh) *	2022-09-22	2023-10-10	南京正科医药股份有限公司	一种托拉塞米晶型ⅰ的精制方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US30633A (en) *		1860-11-13		Improvement in fire-escapes
GB1477664A (en)	1974-04-17	1977-06-22	Christiaens Sa A	Pyridine derivatives
GB1593609A (en) *	1978-01-31	1981-07-22	Christiaens Sa A	Pyridine sulfonamides
LU85193A1 (fr) *	1984-01-31	1985-09-12	Christiaens Sa A	Nouveaux derives de la 4-phenylaminopyridine,leur utilisation et leur preparation

1985
- 1985-08-17 DE DE19853529529 patent/DE3529529A1/de active Granted
1986
- 1986-08-10 IL IL79672A patent/IL79672A/xx not_active IP Right Cessation
- 1986-08-11 CS CS865945A patent/CS259891B2/cs not_active IP Right Cessation
- 1986-08-11 US US06/895,355 patent/US4743693A/en not_active Ceased
- 1986-08-11 CA CA000515676A patent/CA1307277C/en not_active Expired - Lifetime
- 1986-08-11 AU AU61055/86A patent/AU573454B2/en not_active Expired
- 1986-08-12 PT PT83186A patent/PT83186B/pt unknown
- 1986-08-12 EP EP86111118A patent/EP0212537B1/de not_active Expired - Lifetime
- 1986-08-12 NZ NZ217172A patent/NZ217172A/xx unknown
- 1986-08-12 DE DE8686111118T patent/DE3667970D1/de not_active Expired - Lifetime
- 1986-08-13 DK DK385586A patent/DK162518C/da not_active IP Right Cessation
- 1986-08-13 IE IE217986A patent/IE59237B1/en not_active IP Right Cessation
- 1986-08-14 KR KR1019860006689A patent/KR930009818B1/ko not_active Expired - Lifetime
- 1986-08-14 GR GR862139A patent/GR862139B/el unknown
- 1986-08-14 ES ES8601131A patent/ES2001522A6/es not_active Expired
- 1986-08-14 DD DD86293655A patent/DD259858A5/de not_active IP Right Cessation
- 1986-08-15 ZA ZA866151A patent/ZA866151B/xx unknown
- 1986-08-15 HU HU863598A patent/HU195778B/hu unknown
- 1986-08-15 PL PL1986261052A patent/PL146086B1/pl unknown
- 1986-08-15 FI FI863305A patent/FI82189C/fi not_active IP Right Cessation
- 1986-08-15 UA UA4027953A patent/UA7080A1/uk unknown
- 1986-08-15 SU SU864027953A patent/SU1480766A3/ru active
- 1986-08-15 NO NO863305A patent/NO170079C/no not_active IP Right Cessation
- 1986-08-18 JP JP61191789A patent/JPS6245576A/ja active Granted
1987
- 1987-10-20 US US07/111,439 patent/US4822807A/en not_active Ceased
1989
- 1989-10-27 JP JP1278800A patent/JPH0643400B2/ja not_active Expired - Lifetime
1991
- 1991-12-31 CS CS914199A patent/CS419991A3/cs unknown
1992
- 1992-12-03 US US07/985,053 patent/USRE34580E/en not_active Expired - Lifetime
1993
- 1993-04-08 US US08/043,631 patent/USRE34672E/en not_active Expired - Lifetime
- 1993-08-27 LT LTIP898A patent/LT3596B/lt not_active IP Right Cessation
1994
- 1994-06-23 HK HK59994A patent/HK59994A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
LT3596B (en)	1995-12-27
FI863305A0 (fi)	1986-08-15
HUT42069A (en)	1987-06-29
JPH0643400B2 (ja)	1994-06-08
DK162518C (da)	1992-03-30
EP0212537A1 (de)	1987-03-04
CA1307277C (en)	1992-09-08
DK162518B (da)	1991-11-11
US4743693A (en)	1988-05-10
GR862139B (en)	1986-12-30
SU1480766A3 (ru)	1989-05-15
PL146086B1 (en)	1988-12-31
PT83186A (de)	1986-09-01
DE3529529A1 (de)	1987-02-19
EP0212537B1 (de)	1990-01-03
AU573454B2 (en)	1988-06-09
DK385586D0 (da)	1986-08-13
FI863305L (fi)	1987-02-18
PL261052A1 (en)	1987-11-02
US4822807A (en)	1989-04-18
CS419991A3 (en)	1992-06-17
NO170079B (no)	1992-06-01
DE3529529C2 (da)	1987-05-27
LTIP898A (en)	1995-03-27
NO863305D0 (no)	1986-08-15
JPH0415205B2 (da)	1992-03-17
ES2001522A6 (es)	1988-06-01
USRE34580E (en)	1994-04-05
FI82189B (fi)	1990-10-31
PT83186B (pt)	1988-07-01
DE3667970D1 (de)	1990-02-08
JPS6245576A (ja)	1987-02-27
IE862179L (en)	1987-02-17
NO863305L (no)	1987-02-18
HU195778B (en)	1988-07-28
IL79672A (en)	1990-01-18
CS594586A2 (en)	1988-03-15
HK59994A (en)	1994-07-08
ZA866151B (en)	1987-04-29
IE59237B1 (en)	1994-01-26
FI82189C (fi)	1991-02-11
UA7080A1 (uk)	1995-06-30
KR870002076A (ko)	1987-03-30
JPH02191255A (ja)	1990-07-27
AU6105586A (en)	1987-02-19
KR930009818B1 (ko)	1993-10-11
USRE34672E (en)	1994-07-26
DD259858A5 (de)	1988-09-07
IL79672A0 (en)	1986-11-30
CS259891B2 (en)	1988-11-15
NZ217172A (en)	1989-02-24
NO170079C (no)	1992-09-09

Similar Documents

Publication	Publication Date	Title
DK385586D0 (da)	1986-08-13	Fremgangsmaade til fremstilling af en stabil modifikation af torasemid saavel som farmaceutisk praeparat, der indeholder torasemid
DK164408C (da)	1992-11-09	Vaeksthormonfrigivende faktorforbindelser, forbindelserne til anvendelse som terapeutikum, fremgangsmaade til fremstilling af forbindelserne, farmaceutiske praeparater, der indeholder en effektiv maengde af en saadan forbindelse samt anvendelse af forbindelsen
DK380986A (da)	1987-02-11	Fremgangsmaade til fremstilling af piperidinderivater
FI870155L (fi)	1987-07-19	Menetelmä ksantaanikumia sisältävän, kiinteän lääkevalmisteen valmistamiseksi
DK204587A (da)	1987-10-23	Fremgangsmaade til fremstilling af et opbevaringsstabilt koncentrat, til fremstilling af et desinficeringsmiddel
FI871913L (fi)	1987-10-31	Menetelmä oraalisen, farmaseuttisen valmisteen valmistamiseksi, joka on pysyvä värin muuttumista vastaan
FI871914L (fi)	1987-10-31	Menetelmä oraalisen farmaseuttisen valmisteen valmistamiseksi, joka on pysyvä värin muuttumista vastaan
DK340785A (da)	1986-02-02	Quinonderivater, fremgangsmaade til fremstilling af dem og farmaceutisk praeparat indeholdende dem
DK110886D0 (da)	1986-03-11	Hidtil ukendte sulfonylaminoforbindelser, fremgangsmaader til deres fremstilling, og farmaceutiske praeparater, der indeholder forbindelserne
DK345081A (da)	1982-02-05	Fremgangsmaade til fremstilling af et stabilt vandigt praeparat indeholdende invermectin
FI871492A0 (fi)	1987-04-06	Menetelmä lääkeaineina käyttökelpoisten 2-tiometyyli-substituoitujen 1,4-dihydropyridiinien valmistamiseksi
FI880163L (fi)	1988-01-14	Menetelmä lääkeaineena käytettävän liuoksen valmistamiseksi
DK583385A (da)	1986-06-18	Fremgangsmaade til fremstilling af et stabilt nicorandilpraeparat
NO883054L (no)	1989-01-11	Fremgangsmaate for fremstilling av farmasoeytisk preparat inneholdende somatostatinanaloger.
DK58688D0 (da)	1988-02-05	Alkyl(heterocyclymethyl)phenethylamin-forbindelser, farmaceutiske praeparater indeholdende de alkylsulfonylaminosubstituerede forbindelser og anvendelse af disse til fremstilling af et laegemiddel til forhindring eller reduktion af hjertearrytmier
DK349387A (da)	1988-01-09	Nitrofuranderivater samt fremgangsmaade til fremstilling deraf og anvendelse af forbindelserne som laegemiddel
DK528879A (da)	1980-12-14	Fremgangsmaade til fremstilling af et farmaceutisk praeparat indeholdende isosorbiddinitrat
DK220986D0 (da)	1986-05-13	Fremgangsmaade til fremstilling af piperidyliden-dihydrodibenzo(a,d)cycloheptener og aza-derivater deraf, forbindelser vundet ved fremgangsmaaden og disses anvendelse til fremstilling af farmaceutiske kompositioner
DK218985D0 (da)	1985-05-17	Aminocyklopentylaetere, farmaceutiske praeparater indeholdende dem ogfremgangsmaade til fremstilling af dem
DK601785A (da)	1986-06-29	Fremgangsmaade til fremstilling af en hydrothermisk stabil zeolitkatalysator
DK680787D0 (da)	1987-12-22	Farmaceutisk praeparat indeholdende en pyranoquinolinforbindelse
DK343386A (da)	1987-01-21	Fremgangsmaade til fremstilling af 2-cyanamino-pyrimidin-derivater
DK249083D0 (da)	1983-06-01	Fremgangsmade til fremstilling af et pharmaceutisk praeparat til indgivelse af anti-androgent aktive forbindelser
DK163058C (da)	1992-06-09	Triazolethanolderivat, farmaceutiske praeparater indeholdende forbindelsen, forbindelsen til anvendelse som laegemiddel samt fremgangsmaade til fremstilling af forbindelsen
DK164771C (da)	1992-12-28	Fremgangsmaade til fremstilling af et nasalt farmaceutisk praeparat indeholdende ergot-cycliske peptidalkaloider

Legal Events

Date	Code	Title	Description
2006-08-28	PUP	Patent expired