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DK164408C - Vaeksthormonfrigivende faktorforbindelser, forbindelserne til anvendelse som terapeutikum, fremgangsmaade til fremstilling af forbindelserne, farmaceutiske praeparater, der indeholder en effektiv maengde af en saadan forbindelse samt anvendelse af forbindelsen - Google Patents

Vaeksthormonfrigivende faktorforbindelser, forbindelserne til anvendelse som terapeutikum, fremgangsmaade til fremstilling af forbindelserne, farmaceutiske praeparater, der indeholder en effektiv maengde af en saadan forbindelse samt anvendelse af forbindelsen

Info

Publication number
DK164408C
DK164408C DK433485A DK433485A DK164408C DK 164408 C DK164408 C DK 164408C DK 433485 A DK433485 A DK 433485A DK 433485 A DK433485 A DK 433485A DK 164408 C DK164408 C DK 164408C
Authority
DK
Denmark
Prior art keywords
relationships
effective
therapeutic
procedure
preparation
Prior art date
Application number
DK433485A
Other languages
English (en)
Other versions
DK164408B (da
DK433485A (da
DK433485D0 (da
Inventor
Arthur Martin Felix
Edgar P Heimer
Thomas F Mowles
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/653,163 external-priority patent/US4622312A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK433485D0 publication Critical patent/DK433485D0/da
Publication of DK433485A publication Critical patent/DK433485A/da
Publication of DK164408B publication Critical patent/DK164408B/da
Application granted granted Critical
Publication of DK164408C publication Critical patent/DK164408C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK433485A 1984-09-24 1985-09-24 Vaeksthormonfrigivende faktorforbindelser, forbindelserne til anvendelse som terapeutikum, fremgangsmaade til fremstilling af forbindelserne, farmaceutiske praeparater, der indeholder en effektiv maengde af en saadan forbindelse samt anvendelse af forbindelsen DK164408C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/653,163 US4622312A (en) 1984-09-24 1984-09-24 Growth hormone releasing factor analogs
US65316384 1984-09-24
US76289185 1985-08-06
US06/762,891 US4649131A (en) 1984-09-24 1985-08-06 Growth hormone releasing factor analogs

Publications (4)

Publication Number Publication Date
DK433485D0 DK433485D0 (da) 1985-09-24
DK433485A DK433485A (da) 1986-03-25
DK164408B DK164408B (da) 1992-06-22
DK164408C true DK164408C (da) 1992-11-09

Family

ID=27096450

Family Applications (1)

Application Number Title Priority Date Filing Date
DK433485A DK164408C (da) 1984-09-24 1985-09-24 Vaeksthormonfrigivende faktorforbindelser, forbindelserne til anvendelse som terapeutikum, fremgangsmaade til fremstilling af forbindelserne, farmaceutiske praeparater, der indeholder en effektiv maengde af en saadan forbindelse samt anvendelse af forbindelsen

Country Status (11)

Country Link
US (1) US4649131A (da)
EP (1) EP0177819B1 (da)
JP (1) JPH0674279B2 (da)
AU (1) AU589373B2 (da)
CA (1) CA1270598A (da)
DE (1) DE3585867D1 (da)
DK (1) DK164408C (da)
IE (1) IE59240B1 (da)
IL (1) IL76440A (da)
NZ (1) NZ213566A (da)
PH (1) PH23324A (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1271600A (en) * 1985-01-07 1990-07-10 David Howard Coy Growth hormone-releasing peptides and method of treating mammals therewith
US4734399A (en) * 1985-08-06 1988-03-29 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4880778A (en) * 1986-05-12 1989-11-14 Eastman Kodak Company Combinations having synergistic growth hormone releasing activity and methods for use thereof
JPS63243096A (ja) * 1987-03-27 1988-10-07 Sumitomo Pharmaceut Co Ltd ポリペプチドの製造法
US5001223A (en) * 1987-05-26 1991-03-19 Merck & Co., Inc. Parathyroid hormone antagonists with enhanced metabolic properties
US4839344A (en) * 1987-06-12 1989-06-13 Eastman Kodak Company Polypeptide compounds having growth hormone releasing activity
US4801456A (en) * 1987-07-09 1989-01-31 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
USRE33699E (en) * 1987-07-09 1991-09-24 International Minerals & Chemical Corp. Growth hormone-releasing factor analogs
US4880777A (en) * 1987-09-01 1989-11-14 Eastman Kodak Company Synthetic peptides having growth hormone releasing activity
ATE122357T1 (de) * 1988-01-28 1995-05-15 Polygen Holding Corp Polypeptide mit hormonwachstumsbefreiender wirkung.
JPH03502324A (ja) * 1988-01-29 1991-05-30 ジ・アップジョン・カンパニー Ｇｒｆ同族体
US5168102A (en) * 1988-03-18 1992-12-01 University Of Delaware Endocrine manipulation to improve body composition of poultry
US4929600A (en) * 1988-03-18 1990-05-29 University Of Deleware Endocrine manipulation to improve body composition of poultry
US5023322A (en) * 1988-08-31 1991-06-11 Mta Kutatas-Es Szervezetelemzo Intezete Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5756458A (en) * 1989-06-16 1998-05-26 Pharmacia & Upjohn Company Stabilized potent GRF analogs
US5132401A (en) * 1989-09-19 1992-07-21 George Washington University, Office Of Sponsored Research MB-35 a peptide enhancing the production of growth hormone and prolactin from the anterior pituitary
CA2082059A1 (en) * 1990-05-04 1991-11-05 David H. Coy Synthetic grf analogs
NZ238748A (en) * 1990-06-29 1993-09-27 Hoffmann La Roche Growth hormone releasing factor (grf) analogues
ATE119916T1 (de) * 1990-12-10 1995-04-15 Hoffmann La Roche Verfahren zur enzymatischen herstellung von grf(1-44)nh2.
AU662731B2 (en) * 1991-04-09 1995-09-14 F. Hoffmann-La Roche Ag Growth hormone releasing factor analogs
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI
US5246920A (en) * 1992-06-15 1993-09-21 University Of South Florida Treatment of hyperprolactinemia
US5811074A (en) * 1992-06-29 1998-09-22 University Of South Florida Method of diagnosing pituitary dependent growth hormone deficiency
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
JPH11503454A (ja) * 1995-04-14 1999-03-26 ジ アドミニストレイターズ オブ ザ チューレン エデュケイショナル ファンド 成長ホルモン放出因子の類似体
US5990084A (en) * 1996-04-19 1999-11-23 Novo Nordisk A/S Compounds with growth hormone releasing properties
JP2000510453A (ja) * 1996-04-19 2000-08-15 ノボ ノルディスク アクティーゼルスカブ 成長ホルモン遊離特性を有する化合物
US8980249B2 (en) 2010-06-03 2015-03-17 University Of Miami Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets
US9079974B2 (en) 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
EP2934565B1 (en) 2012-12-21 2019-03-13 University of Miami Ghrh agonists for the treatment of ischemic disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4529595A (en) * 1983-01-13 1985-07-16 The Salk Institute For Biological Studies GRF Analogs
US4563352A (en) * 1982-10-04 1986-01-07 The Salk Institute For Biological Studies Human pancreatic GRF
IL70530A (en) * 1983-01-13 1986-09-30 Salk Inst For Biological Studi Synthetic peptides having growth hormone releasing factor activity and compositions containing them
US4518586A (en) * 1983-01-13 1985-05-21 The Salk Institute For Biological Studies GRF Analogs III
US4617149A (en) * 1983-09-21 1986-10-14 Eli Lilly And Company Growth hormone release factor analogs
US4528190A (en) * 1983-10-25 1985-07-09 The Salk Institute For Biological Studies GRF Analogs IV
US4562175A (en) * 1984-02-03 1985-12-31 Ding Chang Synthetic peptides

Also Published As

Publication number Publication date
NZ213566A (en) 1989-01-06
EP0177819B1 (en) 1992-04-15
DK164408B (da) 1992-06-22
IE59240B1 (en) 1994-01-26
IL76440A (en) 1989-08-15
JPH0674279B2 (ja) 1994-09-21
DE3585867D1 (de) 1992-05-21
DK433485A (da) 1986-03-25
CA1270598A (en) 1990-06-19
IE852341L (en) 1986-03-24
DK433485D0 (da) 1985-09-24
AU589373B2 (en) 1989-10-12
EP0177819A3 (en) 1989-02-08
EP0177819A2 (en) 1986-04-16
US4649131A (en) 1987-03-10
PH23324A (en) 1989-07-14
JPS61118400A (ja) 1986-06-05
IL76440A0 (en) 1986-01-31
AU4768385A (en) 1986-04-10

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