DK360888D0 - 3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater - Google Patents

3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater

Info

Publication number: DK360888D0
Authority: DK; Denmark
Prior art keywords: epipodophyllotoxing; lucoside; derivatives; dinitrogen; substituted
Prior art date: 1987-07-01

Application number

DK360888A

Other languages

English (en)

Other versions

DK360888A (da

Inventor

Dolatrai Mohanla Vyas

Mark George Saulnier

John F Kadow

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-01

Filing date

1988-06-30

Publication date

1988-06-30

1988-06-30 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1988-06-30 Publication of DK360888D0 publication Critical patent/DK360888D0/da

1989-01-02 Publication of DK360888A publication Critical patent/DK360888A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK360888A 1987-07-01 1988-06-30 3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater DK360888A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/068,376 US4874851A (en)	1987-07-01	1987-07-01	3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives

Publications (2)

Publication Number	Publication Date
DK360888D0 true DK360888D0 (da)	1988-06-30
DK360888A DK360888A (da)	1989-01-02

Family

ID=22082167

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK360888A DK360888A (da)	1987-07-01	1988-06-30	3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater

Country Status (13)

Country	Link
US (1)	US4874851A (da)
EP (1)	EP0297594A3 (da)
JP (1)	JPS6426592A (da)
KR (1)	KR900006234B1 (da)
AU (1)	AU618536B2 (da)
CA (1)	CA1306250C (da)
DK (1)	DK360888A (da)
FI (1)	FI87357C (da)
IL (1)	IL86888A0 (da)
NO (1)	NO167807C (da)
NZ (1)	NZ225089A (da)
PT (1)	PT87893A (da)
ZA (1)	ZA883762B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4853467A (en) *	1987-05-19	1989-08-01	Bristol-Myers Company	Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4904768A (en) *	1987-08-04	1990-02-27	Bristol-Myers Company	Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4888419A (en) *	1987-08-31	1989-12-19	Bristol-Myers Company	3'-demethoxyepipodophyllotoxin glucoside derivatives
US4965348A (en) *	1989-05-19	1990-10-23	Bristol-Myers Company	Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) *	1989-06-07	1991-07-30	Bristol-Myers Company	Acylated derivatives of etoposide
US6207673B1 (en)	1997-03-12	2001-03-27	The University Of North Carolina At Chapel Hill	Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) *	1997-10-02	2000-04-18	The Board Of Regents Of The University Of Nebraska	Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
KR100377556B1 (ko) *	1999-01-27	2003-03-26	주식회사 엘지생명과학	세픽심 제조에 유용한 중간체의 제조방법
EP1229934B1 (en)	1999-10-01	2014-03-05	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL6613143A (da) *	1965-09-21	1967-03-22
EP0111058B1 (en) *	1982-11-26	1987-11-04	Nippon Kayaku Kabushiki Kaisha	Process for producing 4'-demethyl-epipodophyllotoxin-beta-d-ethylidene-glucoside and acyl-derivative thereof
JPS6032799A (ja) *	1983-07-29	1985-02-19	Microbial Chem Res Found	新規４′−デメチル−４−エピポドフィロトキシン誘導体
JPS60246393A (ja) *	1984-05-22	1985-12-06	Nippon Kayaku Co Ltd	エトポシドの新規製造法
US4609644A (en) *	1984-06-15	1986-09-02	St. Jude Children's Research Hospital	Epipodophyllotoxinquinone glucoside derivatives, method of production and use
JPS61227590A (ja) *	1985-04-02	1986-10-09	Microbial Chem Res Found	新規４′−デメチル−４−エピポドフイロトキシン誘導体
US4853467A (en) *	1987-05-19	1989-08-01	Bristol-Myers Company	Nitrogen containing derivatives of epipodophyllotoxin glucosides

1987
- 1987-07-01 US US07/068,376 patent/US4874851A/en not_active Expired - Fee Related
1988
- 1988-05-26 ZA ZA883762A patent/ZA883762B/xx unknown
- 1988-06-20 NZ NZ225089A patent/NZ225089A/en unknown
- 1988-06-23 KR KR1019880007624A patent/KR900006234B1/ko not_active Expired
- 1988-06-28 IL IL86888A patent/IL86888A0/xx unknown
- 1988-06-28 NO NO882849A patent/NO167807C/no unknown
- 1988-06-28 AU AU18446/88A patent/AU618536B2/en not_active Ceased
- 1988-06-28 FI FI883088A patent/FI87357C/fi not_active IP Right Cessation
- 1988-06-30 DK DK360888A patent/DK360888A/da not_active Application Discontinuation
- 1988-06-30 EP EP88110502A patent/EP0297594A3/en not_active Ceased
- 1988-06-30 CA CA000570935A patent/CA1306250C/en not_active Expired - Fee Related
- 1988-06-30 JP JP63164102A patent/JPS6426592A/ja active Pending
- 1988-07-01 PT PT87893A patent/PT87893A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU618536B2 (en)	1992-01-02
FI883088A7 (fi)	1989-01-02
FI883088A0 (fi)	1988-06-28
DK360888A (da)	1989-01-02
FI87357B (fi)	1992-09-15
NO882849L (no)	1989-01-02
NO167807B (no)	1991-09-02
FI87357C (fi)	1992-12-28
US4874851A (en)	1989-10-17
KR900006234B1 (ko)	1990-08-27
AU1844688A (en)	1989-01-19
EP0297594A3 (en)	1990-07-25
NO167807C (no)	1991-12-11
JPS6426592A (en)	1989-01-27
CA1306250C (en)	1992-08-11
NO882849D0 (no)	1988-06-28
ZA883762B (en)	1989-03-29
KR890002215A (ko)	1989-04-10
NZ225089A (en)	1991-06-25
IL86888A0 (en)	1988-11-30
PT87893A (pt)	1989-06-30
EP0297594A2 (en)	1989-01-04

Publication	Publication Date	Title
NO883299D0 (no)	1988-07-26	Epipodofyllotoksinglukosid-4'-fosfatderivater.
FI884305A7 (fi)	1989-03-22	Uudet amidino-trisyklijohdokset.
DK615186D0 (da)	1986-12-18	Substituerede 5,6-dialkoxyquinazolinderivater
DE3872153D1 (de)	1992-07-23	25-hydroxy-vitamin-d3-derivate.
FI883963A7 (fi)	1989-03-01	Isoxazol- -karbolinderivat.
ATA320788A (de)	1992-12-15	5,5-dimethyl-3-phenylvinyl-1-aminoalkoxy-iminocyclohex-2-enderivate
DK360888D0 (da)	1988-06-30	3',4'-dinitrogen-substituerede epipodophyllotoxinglucosidderivater
DK382788A (da)	1989-01-11	4-amino-substituerede 1,2-dihydroxy-naphthalen-derivater
DK10190D0 (da)	1990-01-12	1,1-dioxo-cephem-4-carbothiolsyrederivater
DE3887281D1 (de)	1994-03-03	1,2,3,4-Tetrahydro-5-nitro-pyrimidin-Derivate.
FI883959A7 (fi)	1989-03-01	3'-demetoxiepipodofyllotoxin -glukosidderivat.
DK702688D0 (da)	1988-12-16	Epipodophyllotoxin-glucosid 4'-acylderivater
DE69122555D1 (de)	1996-11-14	2,4-Dihydroxyadipinsäurederivate
FI880814A7 (fi)	1988-09-11	Imidazodiazepin-derivat.
FI901277A7 (fi)	1990-09-15	2,5,6,7-tetranor-4,8-inter-m-fenyleeni PG1z-johdannaisia
DE3888097D1 (de)	1994-04-07	1,2,3,4-Tetrahydro-5-nitro-pyrimidin-Derivate.
FI893041L (fi)	1989-06-21	Substituerade azacyklohexylderivat.
DE3861208D1 (de)	1991-01-17	Hydroxyalkyl-triazolyl-derivate.
FI881802L (fi)	1988-10-18	Tiadiazolylacetamidocefemderivat.
FI885920L (fi)	1989-06-23	Piperidinylcyklopentylheptensyra -derivat innehaollande vattenhaltiga sammansaettningar.
DK9588A (da)	1988-07-13	2,1-benzothiazepin-2,2-dioxid-5-carboxylsyrederivater
KR880001629A (ko)	1988-04-25	1,3,5-트리티안 유도체
DE3866371D1 (de)	1992-01-09	Diphenylaethylen-derivate.
DK161888A (da)	1988-09-27	Trioxabicyclo (2.2.2) octanderivater
DE3874027D1 (de)	1992-10-01	1,3-dithiol-2-yliden-derivate.

Legal Events

Date	Code	Title	Description
1994-07-11	AHS	Application shelved for other reasons than non-payment